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公开(公告)号:US20180371478A1
公开(公告)日:2018-12-27
申请号:US16123326
申请日:2018-09-06
Applicant: DOW AGROSCIENCES LLC
Inventor: Lakshmi Sastry-Dent , Zehui Cao , Shreedharan Sriram , Steven R. Webb , Debra L. Camper , W. Michael Ainley
Abstract: As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.
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公开(公告)号:US20180100162A1
公开(公告)日:2018-04-12
申请号:US15705312
申请日:2017-09-15
Applicant: Dow AgroSciences LLC
Inventor: Sandeep Kumar , Marcelo Ariel German , Pohao Wang , Todd P. Glancy , Shreedharan Sriram , Carla N. Yerkes , Andrew J. Bowling , Heather Pence , Andrew E. Robinson
IPC: C12N15/82
CPC classification number: C12N15/8218 , C12N15/8223 , C12N15/8234 , C12N15/8274
Abstract: This disclosure concerns the use of endogenous plant RNAi machinery to preferentially or specifically reduce transgene expression. In some embodiments, the disclosure concerns specific reduction of transgene expression in seed tissues of a dicot plant.
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公开(公告)号:US10273493B2
公开(公告)日:2019-04-30
申请号:US14531705
申请日:2014-11-03
Applicant: Dow AgroSciences LLC
Inventor: Lakshmi Sastry-Dent , Zehui Cao , Shreedharan Sriram , Steven R. Webb , Debra L. Camper , Navin Elango
Abstract: As disclosed herein, optimal native genomic loci have been identified in monocot plants, such as maize plants, that represent best sites for targeted insertion of exogenous sequences.
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公开(公告)号:US20170130266A1
公开(公告)日:2017-05-11
申请号:US15333574
申请日:2016-10-25
Applicant: Dow AgroSciences LLC
Inventor: Pohao Wang , Shreedharan Sriram , Lakshmi Sastry-Dent
CPC classification number: C12Q1/6876 , C12N15/82 , C12Q1/6895 , C12Q2600/154 , C12Q2600/158 , G16B20/00 , G16B25/00
Abstract: The present invention is based on the use of the H3K9me2 methylation levels in plant genomes to predict transgene silencing, transgene stability, and/or transgene expression level. Provided are methods and/or systems for generating whole-genome H3K9me2 maps and its use with an assigned threshold value for predicting gene silencing. The methods and/or systems provided herein can be used in high-throughput setting for screening large number of transformed event in a relatively short period of time as compared to existing technologies.
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公开(公告)号:US20200347395A1
公开(公告)日:2020-11-05
申请号:US16758649
申请日:2018-10-29
Applicant: DOW AGROSCIENCES LLC , PIONEER HI-BRED INTERNATIONAL, INC.
Inventor: Lyudmila Sidorenko , Cory M. Larsen , Geny Anthony , Shreedharan Sriram , Holly Jean Butler , Lynne E. Sims , Scott H. Diehn , Gilda M. Rauscher , Kevin G. Ripp , Knut Meyer
IPC: C12N15/82 , C07K14/415
Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmCAB2 gene. Some embodiments relate to a promoter or a 5′ UTR from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3′ UTR or a terminator from a GmCAB2 gene that functions in plants to promote transcription of operably linked nucleotide sequences.
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公开(公告)号:US20200248197A1
公开(公告)日:2020-08-06
申请号:US16856536
申请日:2020-04-23
Applicant: Dow AgroSciences LLC
Inventor: Sandeep Kumar , Marcelo Ariel German , Pahao Wang , Todd P. Glancy , Shreedharan Sriram , Carla N. Yerkes , Andrew J. Bowling , Heather Pence , Andrew E. Robinson
IPC: C12N15/82
Abstract: This disclosure concerns the use of endogenous plant RNAi machinery to preferentially or specifically reduce transgene expression. In some embodiments, the disclosure concerns specific reduction of transgene expression in seed tissues of a dicot plant.
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公开(公告)号:US20190024100A1
公开(公告)日:2019-01-24
申请号:US16112200
申请日:2018-08-24
Applicant: Dow AgroSciences LLC
Inventor: Lakshmi Sastry-Dent , Zehui Cao , Shreedharan Sriram , Steven R. Webb , Debra L. Camper
Abstract: As disclosed herein, optimal native genomic loci from maize plants have been identified that represent best sites for targeted insertion of exogenous sequences.
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公开(公告)号:US09909131B2
公开(公告)日:2018-03-06
申请号:US14531748
申请日:2014-11-03
Applicant: Dow AgroSciences LLC
Inventor: Lakshmi Sastry-Dent , Zehui Cao , Shreedharan Sriram , Steven R. Webb , Debra L. Camper , W. Michael Ainley
CPC classification number: C12N15/8213 , A01H5/10 , C12N15/8243 , C12N15/8273 , C12N15/8274 , C12N15/8286
Abstract: As disclosed herein, optimal native genomic loci of soybean plants have been identified that represent best sites for targeted insertion of exogenous sequences.
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公开(公告)号:US20200318127A1
公开(公告)日:2020-10-08
申请号:US16763406
申请日:2018-10-31
Applicant: Dow AgroSciences LLC
Inventor: Lyudmila Sidorenko , Cory M. Larsen , Geny Anthony , Shreedharan Sriram , Holly Jean Butler
IPC: C12N15/82
Abstract: This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmTEFs1 gene. Some embodiments relate to a promoter or a 5′ UTR from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3′ UTR or a terminator from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences.
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公开(公告)号:US10093940B2
公开(公告)日:2018-10-09
申请号:US14531739
申请日:2014-11-03
Applicant: Dow AgroSciences LLC
Inventor: Lakshmi Sastry-Dent , Zehui Cao , Shreedharan Sriram , Steven R. Webb , Debra L. Camper
Abstract: As disclosed herein, optimal native genomic loci from maize plants have been identified that represent best sites for targeted insertion of exogenous sequences.
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