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公开(公告)号：US10683513B2
公开(公告)日：2020-06-16
申请号：US14577887
申请日：2014-12-19
Applicant: Dow AgroSciences LLC
Inventor： Sandeep Kumar , Marcelo Ariel German , Tristan Coram , Terry R. Wright
IPC: C12N15/82
Abstract: This disclosure concerns the use of endogenous plant RNAi machinery to preferentially or specifically reduce transgene expression. In some embodiments, the disclosure concerns specific reduction of transgene expression in male plant tissues, for example, to provide an economical male sterility system of hybrid seed production.
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公开(公告)号：US10030247B2
公开(公告)日：2018-07-24
申请号：US14587750
申请日：2014-12-31
Applicant: Dow AgroSciences LLC
Inventor： Sandeep Kumar , Manju Gupta , Terry R. Wright , Susan M. Jayne , Doug A. Smith , Diaa Alabed
IPC: C12N15/82
CPC classification number: C12N15/8216
Abstract: The Zea mays c.v. B73 Ubiquitin-1 (Z. mays c.v. B73 Ubi-1) promoter drives high levels of constitutive transgene expression in plants. Repeated use of the same Z. mays c.v. B73 Ubi-1 promoter in multi-gene constructs may also lead to gene silencing, thereby making transgenic products less efficacious. Provided are gene regulatory promoter elements, constructs, and methods for expressing a transgene in plant cells and/or plant tissues using gene regulatory elements from the Ubi-1 promoter of a different Z. mays genotype, Z. mays c.v. Hi-II.
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公开(公告)号：US20170191076A1
公开(公告)日：2017-07-06
申请号：US15452422
申请日：2017-03-07
Applicant: Dow AgroSciences LLC
Inventor： Yunxing C. Cui , Raina King , Tina M. Kaiser , Andrew E. Robinson , Dayakar Pareddy , Sandra G. Toledo , Leon B. Braxton , David M. Anderson , Terry R. Wright
CPC classification number: C12N15/8274 , A01H1/02 , A01N37/38 , A01N39/04 , A01N43/40 , A01N57/20 , C12N9/0069 , C12N9/0071 , C12Q1/6876 , C12Q1/6895 , C12Q2600/13 , C12Q2600/156 , C12Q2600/158 , C12Q2600/16
Abstract: Cotton event pDAB4468.19.10.3 comprises genes encoding AAD-12 and PAT, affording herbicide tolerance to cotton crops containing the event, and enabling methods for crop protection.
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4.发明授权公开(公告)号：US09624505B2
公开(公告)日：2017-04-18
申请号：US14725328
申请日：2015-05-29
Applicant: DOW AGROSCIENCES LLC
Inventor： Justin M. Lira , Erika Snodderley , Andrew E. Robinson , Terry R. Wright , Donald Merlo
CPC classification number: C12N15/8274 , C12N9/0004 , C12N15/8275
Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to a pyridyloxyacetate herbicide. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-13 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
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公开(公告)号：US20170009214A9
公开(公告)日：2017-01-12
申请号：US14491197
申请日：2014-09-19
Applicant: Dow AgroSciences LLC
Inventor： Terry R. Wright , Justin M. Lira , Terence Anthony Walsh , Donald Merlo , Jayakumar Pon Samuel , Gaofeng Lin
CPC classification number: C12N15/8274 , C12N9/0071 , C12N15/8275
Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
Abstract translation: 本发明提供了不仅对2,4-D有抗性的新型植物，而且还提供了对吡啶氧基乙酸酯除草剂的抗性。 迄今为止，没有任何期望或建议，通过引入单一基因可以产生具有这两种有利性质的植物。 本发明还包括与一种或多种其它除草剂抗性基因一起产生本发明一种或多种酶“堆叠”的植物。 本发明能够以新的方式使用除草剂的新型组合。 此外，本发明提供了防止对一种或多种除草剂如草甘膦具有抗性的杂草的发育和控制菌株的新方法。 根据本发明使用的优选酶和基因在本文中称为AAD-12（丙烯酰氧基烷酸酯加氧酶）。 这种高度新颖的发现是显着的除草剂耐受性作物性状和选择性标记机会的基础。
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Patent Agency Ranking
公开(公告)号：US20150184178A1
公开(公告)日：2015-07-02
申请号：US14577887
申请日：2014-12-19
Applicant: Dow AgroSciences LLC
Inventor： Sandeep Kumar , Marcelo Ariel German , Tristan Coram , Terry R. Wright
IPC: C12N15/82
Abstract: This disclosure concerns the use of endogenous plant RNAi machinery to preferentially or specifically reduce transgene expression. In some embodiments, the disclosure concerns specific reduction of transgene expression in male plant tissues, for example, to provide an economical male sterility system of hybrid seed production.
Abstract translation: 本公开涉及使用内源植物RNAi机制来优先或特异性地降低转基因表达。 在一些实施方案中，本公开涉及在雄性植物组织中特异性降低转基因表达，例如提供杂交种子生产的经济雄性不育系统。
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公开(公告)号：US20150080218A1
公开(公告)日：2015-03-19
申请号：US14491197
申请日：2014-09-19
Applicant: Dow AgroSciences LLC
Inventor： Terry R. Wright , Justin M. Lira , Terence Anthony Walsh , Donald Merlo , Pon Samuel Jayakumar , Gaofeng Lin
CPC classification number: C12N15/8274 , C12N9/0071 , C12N15/8275
Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
Abstract translation: 本发明提供了不仅对2,4-D有抗性的新型植物，而且还提供了对吡啶氧基乙酸酯除草剂的抗性。 迄今为止，没有任何期望或建议，通过引入单一基因可以产生具有这两种有利性质的植物。 本发明还包括与一种或多种其它除草剂抗性基因一起产生本发明一种或多种酶“堆叠”的植物。 本发明能够以新的方式使用除草剂的新型组合。 此外，本发明提供了防止对一种或多种除草剂如草甘膦具有抗性的杂草的发育和控制菌株的新方法。 根据本发明使用的优选酶和基因在本文中称为AAD-12（丙烯酰氧基烷酸酯加氧酶）。 这种高度新颖的发现是显着的除草剂耐受性作物性状和选择性标记机会的基础。
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8.发明申请USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES 审中-公开使用和检测抗药性杀草剂的抗药性基因公开(公告)号：US20130040815A1
公开(公告)日：2013-02-14
申请号：US13633515
申请日：2012-10-02
Applicant: Dow AgroSciences LLC
Inventor： Justin M. Lira , Erika Snodderley , Andrew E. Robinson , Terry R. Wright , Donald Merlo
CPC classification number: C12N15/8274 , C12N9/0004 , C12N15/8275
Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to a pyridyloxyacetate herbicide. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-13 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
Abstract translation: 本发明提供了不仅对2,4-D有抗性的新型植物，而且还涉及吡啶氧基乙酸酯除草剂。 本发明还包括产生本发明一种或多种与一种或多种除草剂抗性基因堆叠在一起的酶的植物。 本发明能够以新的方式使用除草剂的新型组合。 此外，本发明提供了防止对一种或多种除草剂如草甘膦具有抗性的杂草的发育和控制菌株的新方法。 根据本发明使用的优选酶和基因在本文中称为AAD-13（丙烯酰氧基烷酸酯加氧酶）。 这种高度新颖的发现是显着的除草剂耐受性作物性状和选择性标记机会的基础。
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9.发明公开公开(公告)号：US20230143169A1
公开(公告)日：2023-05-11
申请号：US17897988
申请日：2022-08-29
Applicant: Dow AgroSciences LLC , M.S. Technologies, L.L.C.
Inventor： Yunxing C. CUI , Thomas Hoffman , Ning Zhou , Stephen N. Novak , Julissa Colon , Dawn M. Parkhursl , Sandra G. Toledo , Terry R. Wright , Sean M. Russell , Bruce Held , Vaithilingam Sekar
CPC classification number: A01N39/04 , C12N9/1092 , C12Y205/01019 , C12N15/8274 , C12Q1/6895 , C12N15/8275 , A01H1/02 , C12N9/93 , C12N15/8241 , C12Y604/01002 , C12Q2600/16 , C12Q2600/13 , C12Q2600/156
Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
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10.发明授权公开(公告)号：US10400250B2
公开(公告)日：2019-09-03
申请号：US15399674
申请日：2017-01-05
Applicant: Dow AgroSciences LLC , M.S. Technologies, L.L.C.
Inventor： Yunxing C. Cui , Thomas Hoffman , Ning Zhou , Stephen N. Novak , Julissa Colon , Dawn M. Parkhurst , Sandra G. Toledo , Terry R. Wright , Sean M. Russell , Bruce Held , Vaithilingam Sekar
Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
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