公开(公告)号：US20170058286A1

公开(公告)日：2017-03-02

申请号：US15352229

申请日：2016-11-15

Applicant: Dow AgroSciences LLC

Inventor： Justin M. Lira ,  Robert Cicchillo ,  Carla N. Yerkes ,  Andrew E. Robinson

IPC: C12N15/82 ,  C07K14/415 ,  C12N9/10

Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.

Abstract translation: 本公开涉及将肽，多肽和蛋白质靶向含质体细胞的质体的组合物和方法。 在一些实施方案中，本公开涉及可将多肽引导至质体的叶绿体转运肽以及编码其的核酸分子。 在一些实施方案中，本公开涉及用于生产包含叶绿体转运肽的转基因植物材料（例如，转基因植物）的方法以及由这些方法生产的植物材料以及由其生产的植物商品。

公开(公告)号：US20160122399A1

公开(公告)日：2016-05-05

申请号：US14928106

申请日：2015-10-30

Applicant: DOW AGROSCIENCES LLC

Inventor： Meghan L.F. Frey ,  Justin M. Lira ,  Xiaoping Xu ,  Ignacio Mario Larrinua ,  Kenneth Narva ,  Timothy D Hey

IPC: C07K14/325 ,  A01N37/46 ,  C12N15/82

CPC classification number: C07K14/325 ,  A01N37/46 ,  C12N15/8286 ,  Y02A40/162

Abstract: DIG-303 insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.

Abstract translation: 公开了DIG-303杀虫毒素，编码这种毒素的多核苷酸，使用这些毒素来控制害虫，以及产生这种毒素的转基因植物。

公开(公告)号：US20160060306A1

公开(公告)日：2016-03-03

申请号：US14830997

申请日：2015-08-20

Applicant: DOW AGROSCIENCES LLC

Inventor： Justin M. Lira ,  Holly Jean Butler ,  Doug A. Smith ,  Kenneth Narva ,  Aaron T. Woosley

IPC: C07K14/325 ,  A01N37/18 ,  C12N15/82

CPC classification number: C07K14/325 ,  A01N37/46 ,  A01N63/02 ,  C12N15/8286 ,  Y02A40/162

Abstract: DIG-14 insecticidal toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.

Abstract translation: 公开了DIG-14杀虫毒素，编码这种毒素的多核苷酸，使用这些毒素来控制害虫，以及产生这种毒素的转基因植物。

公开(公告)号：US08916752B2

公开(公告)日：2014-12-23

申请号：US13647081

申请日：2012-10-08

Applicant: Dow AgroSciences LLC

Inventor： Terry R. Wright ,  Justin M. Lira ,  Terence Anthony Walsh ,  Donald Merlo ,  Jayakumar P. Samuel ,  Gaofeng Lin

IPC: C12N15/82

CPC classification number: C12N15/8274 ,  C12N9/0071 ,  C12N15/8275

Abstract: The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention “stacked” together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.

Abstract translation: 本发明提供了不仅对2,4-D有抗性的新型植物，而且还提供了对吡啶氧基乙酸酯除草剂的抗性。 迄今为止，没有任何期望或建议，通过引入单一基因可以产生具有这两种有利性质的植物。 本发明还包括与一种或多种其它除草剂抗性基因一起产生本发明一种或多种酶“堆叠”的植物。 本发明能够以新的方式使用除草剂的新型组合。 此外，本发明提供了防止对一种或多种除草剂如草甘膦具有抗性的杂草的发育和控制菌株的新方法。 根据本发明使用的优选酶和基因在本文中称为AAD-12（丙烯酰氧基烷酸酯加氧酶）。 这种高度新颖的发现是显着的除草剂耐受性作物性状和选择性标记机会的基础。

公开(公告)号：US10913955B2

公开(公告)日：2021-02-09

申请号：US16150592

申请日：2018-10-03

Applicant: Dow AgroSciences LLC

Inventor： Javier A. Delgado ,  Justin M. Lira ,  Michael T. Sullenberger ,  Robert Cicchillo

IPC: C12N15/82 ,  C07K14/415

Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.

公开(公告)号：US20190127754A1

公开(公告)日：2019-05-02

申请号：US16150592

申请日：2018-10-03

Applicant: Dow AgroSciences LLC

Inventor： Javier A. Delgado ,  Justin M. Lira ,  Michael T. Sullenberger ,  Robert Cicchillo

IPC: C12N15/82 ,  C07K14/415

Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.

公开(公告)号：US20180127760A1

公开(公告)日：2018-05-10

申请号：US15800153

申请日：2017-11-01

Applicant: Dow AgroSciences LLC

Inventor： Javier A. Delgado ,  Justin M. Lira ,  Chaoxian Geng ,  Meghan L. Frey

IPC: C12N15/113 ,  A01N57/16 ,  C12N15/82

CPC classification number: C12N15/1138 ,  A01N57/16 ,  C12N15/8218 ,  C12N15/8282 ,  C12N2310/14

Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of pathogens through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in pathogens. The disclosure also concerns methods for applying dsRNA through formulations and/or transgenic plants that express nucleic acid molecules useful for the control of pathogens, and the plant cells and plants obtained thereby.

公开(公告)号：US09873883B2

公开(公告)日：2018-01-23

申请号：US13757474

申请日：2013-02-01

Applicant: Dow AgroSciences LLC

Inventor： Justin M. Lira ,  Robert M. Cicchillo ,  Carla N. Yerkes ,  Andrew E. Robinson

IPC: C12N15/82 ,  A01H5/00 ,  A01H5/10 ,  C07K14/195 ,  C07K14/415 ,  C12N9/96 ,  C12N9/10 ,  A01N57/20 ,  C12N9/02

CPC classification number: C12N9/1092 ,  A01N57/20 ,  C07K14/415 ,  C07K2319/08 ,  C12N9/0069 ,  C12N9/0071 ,  C12N9/1085 ,  C12N9/96 ,  C12N15/62 ,  C12N15/8205 ,  C12N15/8209 ,  C12N15/8214 ,  C12N15/8221 ,  C12N15/8241 ,  C12N15/8245 ,  C12N15/8247 ,  C12N15/8274 ,  C12N15/8275 ,  C12N15/8281 ,  C12N15/8283 ,  C12N15/8286 ,  C12Y113/00 ,  C12Y114/11 ,  C12Y205/01019 ,  Y02A40/162

Abstract: Provided are plants having glyphosate resistance comprising a nucleic acid encoding a polypeptide having at least 90% identity with SEQ ID NO:1, and parts, organs, seeds, and/or cells of such plants. Also provided are methods for making and growing such a plant, and methods of controlling weeds in a field or area under cultivation containing such plants. For example, some methods comprise the application of multiple herbicides to such plants.

公开(公告)号：US20170022517A1

公开(公告)日：2017-01-26

申请号：US15152305

申请日：2016-05-11

Applicant: Dow AgroSciences LLC

Inventor： Justin M. Lira ,  Robert M. Cicchillo ,  Satish K. Nair

IPC: C12N15/82 ,  C12N9/02 ,  C12N9/10

Abstract: The present disclosure relates to a novel class of EPSPS enzymes, and nucleic acids useful in encoding the same.

Abstract translation: 本公开涉及一类新颖的EPSPS酶和用于编码它们的核酸。

公开(公告)号：US09540654B2

公开(公告)日：2017-01-10

申请号：US13757435

申请日：2013-02-01

Applicant: Dow AgroSciences LLC

Inventor： Justin M. Lira ,  Robert M. Cicchillo ,  Carla N. Yerkes ,  Andrew E. Robinson

IPC: C12N15/82 ,  C12N15/29 ,  C07K14/415 ,  C12N9/96 ,  C12N9/10

CPC classification number: C12N9/1092 ,  A01N57/20 ,  C07K14/415 ,  C07K2319/08 ,  C12N9/0069 ,  C12N9/0071 ,  C12N9/1085 ,  C12N9/96 ,  C12N15/62 ,  C12N15/8205 ,  C12N15/8209 ,  C12N15/8214 ,  C12N15/8221 ,  C12N15/8241 ,  C12N15/8245 ,  C12N15/8247 ,  C12N15/8274 ,  C12N15/8275 ,  C12N15/8281 ,  C12N15/8283 ,  C12N15/8286 ,  C12Y113/00 ,  C12Y114/11 ,  C12Y205/01019 ,  Y02A40/162

Abstract: This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.

Abstract translation: 本公开涉及将肽，多肽和蛋白质靶向含质体细胞的质体的组合物和方法。 在一些实施方案中，本公开涉及可将多肽引导至质体的叶绿体转运肽以及编码其的核酸分子。 在一些实施方案中，本公开涉及用于生产包含叶绿体转运肽的转基因植物材料（例如，转基因植物）的方法以及由这些方法生产的植物材料以及由其生产的植物商品。