公开(公告)号：US20190314269A1

公开(公告)日：2019-10-17

申请号：US16343126

申请日：2017-10-26

Applicant: DSM IP ASSETS B.V.

Inventor： Dominik IMFELD ,  Rolf SCHUETZ ,  Eliane Ursula WANDELER

IPC: A61K8/9706 ,  A61K8/73 ,  A61K8/55 ,  A61K8/06 ,  A61Q17/00

Abstract: The present application relates to a method of protecting keratinocytes against the effects of air pollution caused by introduction of dust particles, fumes or smoke into the atmosphere such as in particular against the harmful effects of diesel and urban dust particular matter, said method including applying to the skin a cosmetic composition containing an effective amount of an active selected from the group consisting of pullulan and a nannochloropsis occulata extract as well as mixtures thereof.

公开(公告)号：US20180353563A1

公开(公告)日：2018-12-13

申请号：US16060096

申请日：2016-12-09

Applicant: DSM IP ASSETS B.V.

Inventor： Remo CAMPICHE ,  Dominik IMFELD ,  Eileen JACKSON ,  Eliane Ursula WANDELER

IPC: A61K38/05 ,  A61K8/06 ,  A61K8/64 ,  A61K8/55 ,  A61K9/107 ,  A61K47/24 ,  A61P17/08 ,  A61P17/10 ,  A61Q19/00

CPC classification number: A61K38/05 ,  A61K8/062 ,  A61K8/55 ,  A61K8/64 ,  A61K9/107 ,  A61K47/24 ,  A61P17/08 ,  A61P17/10 ,  A61Q19/00 ,  A61Q19/008 ,  A61Q19/02

Abstract: The present invention relates to a novel use of proline containing dipeptides for the prevention and/or treatment of skin conditions associated with altered, damaged or malfunctioning sebaceous glands.

公开(公告)号：US20180319829A1

公开(公告)日：2018-11-08

申请号：US15774649

申请日：2016-11-23

Applicant: DSM IP ASSETS B.V.

Inventor： Stéphanie BOUDON ,  Eileen JACKSON ,  Rolf SCHUETZ ,  Jürgen Herbert VOLLHARDT ,  Peter WIKSTROEM ,  Eliane Ursula WANDELER

IPC: C07F9/6553 ,  A61K8/55 ,  A61K31/67 ,  A61Q19/00 ,  A61Q19/08 ,  C07F9/30 ,  A61K31/662 ,  C07F9/572 ,  A61K31/675 ,  C07C53/18

CPC classification number: C07F9/655354 ,  A61K8/55 ,  A61K8/64 ,  A61K31/662 ,  A61K31/67 ,  A61K31/675 ,  A61Q19/00 ,  A61Q19/08 ,  C07C53/18 ,  C07F9/306 ,  C07F9/5728

Abstract: This invention relates to compounds that are selective inhibitors of Matrix Metalloprotease-12 (MMP-12), to cosmetic and pharmaceutical compositions containing them, and to their use in the prevention and/or treatment of ailments associated with MMP-12. Formula (I).