公开(公告)号：US20180319829A1

公开(公告)日：2018-11-08

申请号：US15774649

申请日：2016-11-23

Applicant: DSM IP ASSETS B.V.

Inventor： Stéphanie BOUDON ,  Eileen JACKSON ,  Rolf SCHUETZ ,  Jürgen Herbert VOLLHARDT ,  Peter WIKSTROEM ,  Eliane Ursula WANDELER

IPC: C07F9/6553 ,  A61K8/55 ,  A61K31/67 ,  A61Q19/00 ,  A61Q19/08 ,  C07F9/30 ,  A61K31/662 ,  C07F9/572 ,  A61K31/675 ,  C07C53/18

CPC classification number: C07F9/655354 ,  A61K8/55 ,  A61K8/64 ,  A61K31/662 ,  A61K31/67 ,  A61K31/675 ,  A61Q19/00 ,  A61Q19/08 ,  C07C53/18 ,  C07F9/306 ,  C07F9/5728

Abstract: This invention relates to compounds that are selective inhibitors of Matrix Metalloprotease-12 (MMP-12), to cosmetic and pharmaceutical compositions containing them, and to their use in the prevention and/or treatment of ailments associated with MMP-12. Formula (I).

公开(公告)号：US20170304169A1

公开(公告)日：2017-10-26

申请号：US15517256

申请日：2015-10-15

Applicant: DSM IP ASSETS B.V.

Inventor： Dominik IMFELD ,  Alexander RADSPIELER ,  Rolf SCHUETZ

IPC: A61K8/365 ,  A61Q19/02 ,  A61Q19/00 ,  A61Q17/04 ,  A61Q7/00 ,  A61Q19/08 ,  A61K8/67

CPC classification number: A61K8/365 ,  A61K8/671 ,  A61Q7/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08

Abstract: The present invention relates to the cosmetic use of topical compositions comprising 10-hydroxystearic acid, a salt or ester thereof, for application to human skin for improving the condition and appearance of skin more particularly as an anti-wrinkle, for promoting a homogenous skin tone, for reduction of skin pore size, as a photo-protecting agent, and/or for improvement of the skin barrier function.

公开(公告)号：US20250161329A1

公开(公告)日：2025-05-22

申请号：US18873493

申请日：2023-06-07

Applicant: DSM IP ASSETS B.V.

Inventor： Rolf SCHUETZ ,  Jürgen Herbert VOLLHARDT

IPC: A61K31/60 ,  A61K8/35 ,  A61K8/365 ,  A61K8/40 ,  A61K31/12 ,  A61K31/275 ,  A61P17/10 ,  A61Q17/04

Abstract: The present invention relates to the use of selected UV filters selected from the group consisting of octocrylene, ethylhexyl salicylate and butyl methoxydibenzoylmethane to reduce the abundance of C. acnes strains in a skin microbiome after UV radiation. Said use is suitable to prevent and or treat the progression of acne, in particular the progression of acne exacerbated by sunscreen application.

公开(公告)号：US20240009102A1

公开(公告)日：2024-01-11

申请号：US18254537

申请日：2021-11-26

Applicant: DSM IP Assets B.V.

Inventor： Anne JANSSEN ,  Gernot Ulrich KUNZE ,  Karina RADOMSKY ,  Rolf SCHUETZ ,  Jürgen Herbert VOLLHARDT

IPC: A61K8/49 ,  A61K8/37 ,  A61K8/27 ,  A61K8/29 ,  A61K8/06 ,  A61Q17/04

CPC classification number: A61K8/4966 ,  A61K8/37 ,  A61K8/27 ,  A61K8/29 ,  A61K8/062 ,  A61Q17/04 ,  A61K2800/30 ,  A61K2800/621 ,  A61K2800/624 ,  A61K2800/63

Abstract: The present invention relates to specific topical compositions comprising bis-ethylhexyloxyphenol methoxyphenyl triazine (BEMT), butyloctyl salicylate and at least one inorganic UV-filter selected from titanium dioxide and zinc oxide. Said compositions exhibit an appealing skin feel and look.

公开(公告)号：US20240130944A1

公开(公告)日：2024-04-25

申请号：US18277048

申请日：2022-02-08

Applicant: DSM IP Assets B.V.

Inventor： Dominik IMFELD ,  Rolf SCHUETZ ,  Anthony RAWLINGS

IPC: A61K8/49 ,  A61K8/46 ,  A61Q19/08

CPC classification number: A61K8/494 ,  A61K8/466 ,  A61K8/4946 ,  A61Q19/08

Abstract: The present invention relates to use of certain amidino substituted amino acid derivatives as lecithin retinol acyltransferase inhibitors (LRAT inhibitors), to cosmetic compositions comprising said amino acid derivatives as well as the use thereof for the treatment of skin ageing.

公开(公告)号：US20210222144A1

公开(公告)日：2021-07-22

申请号：US15734370

申请日：2019-06-04

Applicant: DSM IP Assets B.V.

Inventor： Harald PICHLER ,  Martin SCHÜRMANN ,  Rolf SCHUETZ ,  Matthias ENGLEDER ,  Gernot STROHMEIER

IPC: C12N9/88 ,  C11C3/00

Abstract: The present invention relates to regio- and stereoselective hydration of oleic acid derivatives, including esters of oleic acid, by action of modified oleate hydratase.

公开(公告)号：US20190314269A1

公开(公告)日：2019-10-17

申请号：US16343126

申请日：2017-10-26

Applicant: DSM IP ASSETS B.V.

Inventor： Dominik IMFELD ,  Rolf SCHUETZ ,  Eliane Ursula WANDELER

IPC: A61K8/9706 ,  A61K8/73 ,  A61K8/55 ,  A61K8/06 ,  A61Q17/00

Abstract: The present application relates to a method of protecting keratinocytes against the effects of air pollution caused by introduction of dust particles, fumes or smoke into the atmosphere such as in particular against the harmful effects of diesel and urban dust particular matter, said method including applying to the skin a cosmetic composition containing an effective amount of an active selected from the group consisting of pullulan and a nannochloropsis occulata extract as well as mixtures thereof.