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公开(公告)号：US20110134420A1
公开(公告)日：2011-06-09
申请号：US13055240
申请日：2009-07-22
申请人： Daisuke Matsumoto , Yasunori Shiraki , Michio Naka
发明人： Daisuke Matsumoto , Yasunori Shiraki , Michio Naka
IPC分类号： G01N21/05
CPC分类号： G01N21/05 , B01L3/502715 , B01L2300/0654 , B01L2300/0822 , B01L2300/0877 , G01N21/0303 , G01N27/44791 , G01N2021/0346 , G01N2021/056 , G01N2201/0642
摘要： The present invention relates to a microchip 1 having a translucent member 11, a flow channel 10 or a cell formed at a side of the translucent member 11 where light enters, and an aperture 16 formed at a position corresponding to the flow channel 10 or the cell at a side of a translucent member 10 where light goes out. The aperture 16 has a light go-through surface 17 which causes light flux being emitted from the flow channel 10 or the cell to go through and a light reflective surface 18 that totally reflects the incident light flux. A width size W1 of the light go-through surface 17 is smaller than a width size W2 of the flow channel 10 or the cell.
摘要翻译： 本发明涉及一种微芯片1，其具有半透明部件11，流路10或形成在透光部件11的光入射侧的单元，以及形成在对应于流路10或 电池在光出射的半透明构件10的一侧。 孔16具有光通过表面17，其使得从流动通道10或单元发射的光束通过;以及全反射入射光通量的光反射表面18。 光透过表面17的宽度尺寸W1小于流路10或单元的宽度尺寸W2。
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公开(公告)号：US08436990B2
公开(公告)日：2013-05-07
申请号：US13055240
申请日：2009-07-22
申请人： Daisuke Matsumoto , Yasunori Shiraki , Michio Naka
发明人： Daisuke Matsumoto , Yasunori Shiraki , Michio Naka
IPC分类号： G01N21/05
CPC分类号： G01N21/05 , B01L3/502715 , B01L2300/0654 , B01L2300/0822 , B01L2300/0877 , G01N21/0303 , G01N27/44791 , G01N2021/0346 , G01N2021/056 , G01N2201/0642
摘要： The present invention relates to a microchip 1 having a translucent member 11, a flow channel 10 or a cell formed at a side of the translucent member 11 where light enters, and an aperture 16 formed at a position corresponding to the flow channel 10 or the cell at a side of a translucent member 10 where light goes out. The aperture 16 has a light go-through surface 17 which causes light flux being emitted from the flow channel 10 or the cell to go through and a light reflective surface 18 that totally reflects the incident light flux. A width size W1 of the light go-through surface 17 is smaller than a width size W2 of the flow channel 10 or the cell.
摘要翻译： 本发明涉及一种微芯片1，其具有半透明部件11，流路10或形成在透光部件11的光入射侧的单元，以及形成在对应于流路10或 电池在光出射的半透明构件10的一侧。 孔16具有光通过表面17，其使得从流动通道10或单元发射的光束通过;以及全反射入射光通量的光反射表面18。 光透过表面17的宽度尺寸W1小于流路10或单元的宽度尺寸W2。
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公开(公告)号：US08654323B2
公开(公告)日：2014-02-18
申请号：US13241960
申请日：2011-09-23
IPC分类号： G01J1/00
CPC分类号： G01N27/44721 , B01L3/502715 , B01L9/527 , B01L2300/0654 , G01N21/0303 , G01N21/05 , G01N2021/0346 , G01N2201/0245
摘要： An analyzing apparatus includes a microchip, a detecting unit and an analyzing-measuring unit. The microchip is formed of a light transmissive material formed with a separation fluid channel that is a light measuring part. The detecting unit includes an emitted-light guiding unit that emits light to the separation fluid channel, and a received-light guiding unit that receives light through the separation fluid channel. The emitted-light guiding unit or the received-light guiding unit placed at a position facing a microchip support table via the microchip abuts the microchip, and pushes the microchip in a direction toward the microchip support table. The analyzing-measuring unit includes the detecting unit, the emitted-light guiding unit and the received-light guiding unit, and detects a constituent of a sample filled in the separation fluid channel.
摘要翻译： 分析装置包括微芯片，检测单元和分析测量单元。 微芯片由形成有作为光测量部分的分离流体通道形成的透光材料形成。 检测单元包括向分离流体通道发射光的发射光引导单元和通过分离流体通道接收光的接收光引导单元。 经由微芯片放置在面向微芯片支撑台的位置处的发射光引导单元或接收光引导单元抵靠微芯片，并且朝向微芯片支撑台的方向推动微芯片。 分析测量单元包括检测单元，发射光引导单元和接收光引导单元，并且检测填充在分离流体通道中的样品的成分。
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公开(公告)号：US20120048734A1
公开(公告)日：2012-03-01
申请号：US13217790
申请日：2011-08-25
IPC分类号： G01N27/447 , G01N27/453
CPC分类号： G01N27/44756 , B01L3/502753 , G01N27/44721 , G01N27/44743 , G01N30/18 , G01N35/1095
摘要： An analysis apparatus is provided with a storage tank, an injection nozzle, a syringe, a collection nozzle, a test sample tank, a microchip having two or more separation channels, detectors, a waste liquid tank, a controller, and a power supply. The collection nozzle collects a specimen which becomes a test sample from a test sample container housing the specimen, and transfers the specimen to the test sample tank. The separation channels separate characteristic components contained in the test sample. The injection nozzle is distanced from the collection nozzle and injects the test sample from the test sample tank into the separation channels. The detectors detect the separated characteristic components in the separation channels.
摘要翻译： 分析装置设置有储罐，注射喷嘴，注射器，收集喷嘴，试样罐，具有两个或更多个分离通道的微芯片，检测器，废液罐，控制器和电源。 收集喷嘴从容纳样品的试样容器收集成为试样的样品，并将试样转移到试样罐中。 分离通道分离测试样品中包含的特征成分。 注射喷嘴与收集喷嘴间隔开，并将测试样品从测试样品槽注入分离通道。 检测器检测分离通道中分离的特征成分。
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公开(公告)号：US20090123337A1
公开(公告)日：2009-05-14
申请号：US11922520
申请日：2006-06-21
IPC分类号： G01N33/50
CPC分类号： G01N1/38 , G01N2001/1056 , G01N2015/0073 , G01N2015/008 , G01N2015/0084 , G01N2035/00544
摘要： A cartridge A to be mounted to a separate apparatus is provided. The cartridge includes a liquid introduction port 3 for introducing a sample liquid, and a diluter 4 including a diluent tank 41 for storing a diluent 40 for diluting the sample liquid, a sample liquid measurer 43 for separating a predetermined amount of sample liquid from the sample liquid introduced from the liquid introduction port 3, and a dilution tank 42A for mixing at least part of the sample liquid and at least part of the diluent. The sample liquid measurer 4 includes an introduction flow path 43a extending from the liquid introduction port 3, and a measurement flow path 43c and, an overflow path 43d which are connected to the introduction flow path 43a via a branch portion 43b. The measurement flow path 43c extends toward the dilution tank 42A.
摘要翻译： 提供了要安装到单独设备的盒A。 墨盒包括用于引入样品液体的液体引入口3和稀释剂4，稀释剂4包括用于储存用于稀释样品液体的稀释剂40的稀释剂罐41，用于从样品中分离预定量的样品液体的样品液体测量器43 从液体导入口3引入的液体，以及用于混合至少一部分样品液体和至少部分稀释剂的稀释罐42A。 样品液体测量器4包括从液体引入口3延伸的引入流动路径43a和经由分支部分43b连接到引入流动路径43a的测量流动路径43c和溢出路径43d。 测量流路43c朝向稀释槽42A延伸。
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6.发明申请Method of Sampling Specimen, Test Method and Dropping Pipette and Specimen Sampler to be Used Therein 审中-公开样品取样方法，测试方法和滴管移液器及样品采样器公开(公告)号：US20120132015A1
公开(公告)日：2012-05-31
申请号：US13359841
申请日：2012-01-27
IPC分类号： G01N1/22
CPC分类号： B01L3/0272 , B01L3/0282 , B01L3/50825 , B01L3/5635 , B01L2200/026 , B01L2400/0481 , G01N35/1079
摘要： A method for taking a sample includes drawing blood into a vacuum blood collection tube and transferring at least part of the blood from the vacuum blood collection tube to a sample storage space of a dropper. The vacuum blood collection tube includes a sample storage portion and a stopper sealing the sample storage portion, and the drawing is performed by stabbing a hollow needle into the stopper. The dropper includes and internal space at least part of which is the sample storage space for storing a sample and which includes a volume changeable space defined by an elastically deformable portion having flexibility. The dropper further includes an insertion portion including a through-hole connected to the internal space, and the transfer of the sample is performed by inserting the insertion portion into a through-hole formed in the stopper by the stabbing of the hollow needl into the stopper.
摘要翻译： 采集样品的方法包括将血液抽吸到真空采血管中并将至少部分血液从真空采血管转移到滴管的样品储存空间。 真空采血管包括样品收集部分和密封样品收集部分的止动件，并且通过将中空针刺入塞子中来进行拉伸。 滴管包括内部空间，其至少一部分是用于存储样品的样品存储空间，并且其包括由具有柔性的可弹性变形部分限定的体积可变空间。 该滴管还包括插入部分，该插入部分包括连接到内部空间的通孔，并且通过将中空针头刺入塞子中而将插入部分插入形成在止动件中的通孔中来进行样品的转移 。
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公开(公告)号：US08721859B2
公开(公告)日：2014-05-13
申请号：US13427037
申请日：2012-03-22
IPC分类号： G01N27/447 , B01D57/02 , C07K1/26 , G01N27/403
CPC分类号： G01N27/44708 , B01D57/02 , G01N27/44713 , G01N27/44721 , G01N27/44791
摘要： An analysis apparatus is an apparatus that performs electrophoresis using a microchip provided with a channel. The analysis apparatus includes a cooling unit (an electron cooling element and a driving circuit) that cools the microchip, a voltage application unit (electrodes and a power supply circuit) that applies voltage to a buffer solution filled in the channel of the microchip, an optical analysis unit (a light source, a light receiving element, and an analysis unit) that conducts, through the microchip, optical analysis of a sample introduced in the channel, and a control unit that controls the cooling unit, the voltage application unit, and the optical analysis unit. The control unit causes the cooling unit to start cooling the microchip, and after the microchip has been cooled, causes the voltage application unit and the optical analysis unit to operate.
摘要翻译： 分析装置是使用设置有通道的微芯片进行电泳的装置。 分析装置包括冷却微芯片的冷却单元（电子冷却元件和驱动电路），向填充在微芯片的通道中的缓冲溶液施加电压的电压施加单元（电极和电源电路）， 光学分析单元（光源，光接收元件和分析单元），其通过微芯片对通道中引入的样品进行光学分析;以及控制单元，其控制冷却单元，电压施加单元， 和光学分析单元。 控制单元使冷却单元开始冷却微芯片，并且在微芯片冷却之后，使电压施加单元和光学分析单元工作。
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公开(公告)号：US08506785B2
公开(公告)日：2013-08-13
申请号：US13196578
申请日：2011-08-02
IPC分类号： G01N27/453
CPC分类号： B01L3/502715 , B01L2300/0816 , B01L2400/0421 , G01N27/44713
摘要： An analysis apparatus enables a plurality of analysis processes to be accurately and efficiently performed. The analysis apparatus includes a detention tank in which a specimen is stored, and a voltage applier. The voltage applier includes a power source and a contact tip to be brought into contact with the specimen for applying a voltage necessary for analyzing the specimen. The voltage applier renews the contact tip from a used state to an unused state after completing an analysis and before starting the subsequent analysis.
摘要翻译： 分析装置能够准确且有效地执行多个分析处理。 分析装置包括其中存储有试样的滞留罐和施压器。 电压施加器包括电源和与样品接触的接触尖端以施加分析样品所需的电压。 电压施加器在完成分析之后和开始后续分析之前将接触尖端从使用状态更新为未使用状态。
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公开(公告)号：US20120031761A1
公开(公告)日：2012-02-09
申请号：US13196578
申请日：2011-08-02
IPC分类号： G01N27/447
CPC分类号： B01L3/502715 , B01L2300/0816 , B01L2400/0421 , G01N27/44713
摘要： An analysis apparatus enables a plurality of analysis processes to be accurately and efficiently performed. The analysis apparatus includes a detention tank in which a specimen is stored, and a voltage applier. The voltage applier includes a power source and a contact tip to be brought into contact with the specimen for applying a voltage necessary for analyzing the specimen. The voltage applier renews the contact tip from a used state to an unused state after completing an analysis and before starting the subsequent analysis.
摘要翻译： 分析装置能够准确且有效地执行多个分析处理。 分析装置包括其中存储有试样的滞留罐和施压器。 电压施加器包括电源和与样品接触的接触尖端以施加分析样品所需的电压。 电压施加器在完成分析之后和开始后续分析之前将接触尖端从使用状态更新为未使用状态。
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公开(公告)号：US20080101991A1
公开(公告)日：2008-05-01
申请号：US11884849
申请日：2006-06-16
IPC分类号： B01J19/00
CPC分类号： G01N35/08 , B01F13/0059 , B01F13/0818 , G01N2035/00524
摘要： The present invention provides an analysis tool that can achieve excellent stirring efficiency and can yield highly accurate and reliable analytical values. An analysis tool 1 for analyzing a component in a sample by reacting it with a reagent includes: the reagent, a magnetic material for stirring the sample and the reagent to mix them together; and a reagent arrangement portion 13. In the reagent arrangement portion 13, the reagent and the magnetic material are provided separately (the reagent parts 17 and the magnetic material part 18), and the magnetic material is fixed to the reagent arrangement portion 13 (the magnetic material part 18) with a water-soluble paste. As the water-soluble paste, it is possible to use carboxymethyl cellulose, for example. As the magnetic material, it is possible to use magnetic beads, for example.
摘要翻译： 本发明提供一种分析工具，其可以获得优异的搅拌效率并且可以产生高精度和可靠的分析值。 用于通过与样品反应来分析样品中的组分的分析工具1包括：试剂，用于搅拌样品的磁性材料和试剂混合在一起; 和试剂配置部13。 在试剂配置部13中，分别设置试剂和磁性体（试剂部17和磁性体部18），将磁性体固定于试剂配置部13（磁性体18） 水溶性糊剂。 作为水溶性糊剂，例如可以使用羧甲基纤维素。 作为磁性材料，例如可以使用磁珠。
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