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公开(公告)号：US08901489B2
公开(公告)日：2014-12-02
申请号：US14126259
申请日：2012-06-15
申请人： Daniel Levin , Vlad Sergeyev , Volodimir Bondarenko , Bohdan Atamanchuk , Qunzhou Bian , Henryk Zaleski , Mark Piniarski , Simon Feldberg , Ronald Jackson
发明人： Daniel Levin , Vlad Sergeyev , Volodimir Bondarenko , Bohdan Atamanchuk , Qunzhou Bian , Henryk Zaleski , Mark Piniarski , Simon Feldberg , Ronald Jackson
CPC分类号： G01N27/622 , H01J49/12 , H01J49/168
摘要： Looped ionization sources for ion mobility spectrometers are described. The ionization sources can be used to ionize molecules from a sample of interest in order to identify the molecules based on the ions. In an implementation, an electrical ionization source includes a wire that is looped between electrical contacts. The wire is used to form a corona responsive to application of voltage between the wire and the walls of an ionization chamber. The corona can form when a sufficient voltage is applied between the wire and the walls. A difference in electrical potential between the wire and a wall forming an ionization chamber, in which wire is contained, can be used to draw the ions away from the wire. In embodiments, the wire can be heated to reduce the voltage used to strike the corona. The ions, subsequently, may ionize the molecules from the sample of interest. The looped corona source can also be used in mass spectrometers (MS).
摘要翻译： 描述了用于离子迁移率光谱仪的环形电离源。 电离源可以用于从感兴趣的样品中离子化分子，以便基于离子鉴定分子。 在一个实施方案中，电离电离源包括在电触头之间环绕的导线。 导线用于响应于在电线和电离室的壁之间施加电压而形成电晕。 当电线和墙壁之间施加足够的电压时，可以形成电晕。 电线和形成电离室的壁之间的电位差可以用于将离子从电线中吸出。 在实施例中，可以加热导线以降低用于击打电晕的电压。 离子，随后可能离开目标样品的分子。 环形电晕源也可用于质谱仪（MS）。
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公开(公告)号：US20140246581A1
公开(公告)日：2014-09-04
申请号：US14126259
申请日：2012-06-15
申请人： Daniel Levin , Vlad Sergeyev , Volodimir Bondarenko , Bohdan Atamanchuk , Qunzhou Bian , Henryk Zaleski , Mark Piniarski , Simon Feldberg , Ronald Jackson
发明人： Daniel Levin , Vlad Sergeyev , Volodimir Bondarenko , Bohdan Atamanchuk , Qunzhou Bian , Henryk Zaleski , Mark Piniarski , Simon Feldberg , Ronald Jackson
CPC分类号： G01N27/622 , H01J49/12 , H01J49/168
摘要： Looped ionization sources for ion mobility spectrometers are described. The ionization sources can be used to ionize molecules from a sample of interest in order to identify the molecules based on the ions. In an implementation, an electrical ionization source includes a wire that is looped between electrical contacts. The wire is used to form a corona responsive to application of voltage between the wire and the walls of an ionization chamber. The corona can form when a sufficient voltage is applied between the wire and the walls. A difference in electrical potential between the wire and a wall forming an ionization chamber, in which wire is contained, can be used to draw the ions away from the wire. In embodiments, the wire can be heated to reduce the voltage used to strike the corona. The ions, subsequently, may ionize the molecules from the sample of interest. The looped corona source can also be used in mass spectrometers (MS).
摘要翻译： 描述了用于离子迁移率光谱仪的环形电离源。 电离源可以用于从感兴趣的样品中离子化分子，以便基于离子鉴定分子。 在一个实施方案中，电离电离源包括在电触头之间环绕的导线。 导线用于响应于在电线和电离室的壁之间施加电压而形成电晕。 当电线和墙壁之间施加足够的电压时，可以形成电晕。 电线和形成电离室的壁之间的电位差可以用于将离子从电线中吸出。 在实施例中，可以加热导线以降低用于击打电晕的电压。 离子，随后可能离开目标样品的分子。 环形电晕源也可用于质谱仪（MS）。
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3.发明授权公开(公告)号：US09983099B2
公开(公告)日：2018-05-29
申请号：US12997358
申请日：2009-06-10
CPC分类号： G01N1/02 , G01N27/62 , G01N27/622 , G01N35/00584 , G01N2001/028 , G01N2001/4038 , G01N2035/0097 , Y10T436/115831
摘要： An ion mobility spectrometer analytical instrument, including an ion mobility spectrometer, a swab interface, and a desorber assembly. The desorber assembly includes a heat transfer device configured to heat a desorber, as well as a supply configured to direct gas through the desorber. The instrument further includes a drift tube, high voltage device arrayed, at least in part, proximate to the drift tube, wherein the high voltage device is configured to change a polarity of a voltage applied to the drift tube and have an absolute voltage of about 500 to 1500 volts. The instrument further includes a reactant supply unit adapted to supply reactant during a sample substance analysis, and a control unit.
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公开(公告)号：US20110223674A1
公开(公告)日：2011-09-15
申请号：US12997358
申请日：2009-06-10
IPC分类号： G01N35/00
CPC分类号： G01N1/02 , G01N27/62 , G01N27/622 , G01N35/00584 , G01N2001/028 , G01N2001/4038 , G01N2035/0097 , Y10T436/115831
摘要： An ion mobility spectrometer analytical instrument, including an ion mobility spectrometer, a swab interface, and a desorber assembly. The desorber assembly includes a heat transfer device configured to heat a desorber, as well as a supply configured to direct gas through the desorber. The instrument further includes a drift tube, high voltage device arrayed, at least in part, proximate to the drift tube, wherein the high voltage device is configured to change a polarity of a voltage applied to the drift tube and have an absolute voltage of about 500 to 1500 volts. The instrument further includes a reactant supply unit adapted to supply reactant during a sample substance analysis, and a control unit.
摘要翻译： 离子迁移谱仪分析仪器，包括离子迁移谱仪，拭子界面和解吸器组件。 解吸器组件包括被配置为加热解吸器的热传递装置，以及被构造成引导气体通过解吸器的供应源。 所述仪器还包括漂移管，至少部分地靠近所述漂移管排列的高压装置，其中所述高电压装置被配置为改变施加到所述漂移管的电压的极性，并且具有约 500至1500伏。 仪器还包括适于在样品物质分析期间供应反应物的反应物供应单元和控制单元。
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