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12 条记录 (耗时 0.03 秒)

    Belactosin derivatives as therapeutic agents/biological probes and their synthesis
    1.
    发明授权
    Belactosin derivatives as therapeutic agents/biological probes and their synthesis 失效
    贝米松星衍生物作为治疗剂/生物探针及其合成

    公开(公告)号：US08119653B2

    公开(公告)日：2012-02-21

    申请号：US11775154

    申请日：2007-07-09

    申请人： Daniel Romo ,  Sung Wook Cho ,  Jeffrey W. Smith ,  Robyn D. Richardson

    发明人： Daniel Romo ,  Sung Wook Cho ,  Jeffrey W. Smith ,  Robyn D. Richardson

    IPC分类号： A61K31/436 ,  C07D221/18

    CPC分类号： C07D407/12 ,  C07D305/12

    摘要： Derivatives of belactosin and their synthesis are disclosed. In certain embodiments, compounds of the present invention exhibit anti-cancer, antiviral, antibiotic, and/or auto-immune therapeutic abilities. In general, methods of synthesis disclosed herein allow for introduction of a variety of substituents at numerous positions as well as the facile introduction of a beta-lactone ring moiety. The synthetic steps comprise, in preferred embodiments, a tandem Mukaiyama aldol lactonization reaction. Data demonstrating the utility of some of the derivatives as proteasome inhibitors is also disclosed.

    摘要翻译： 披露了双乳糖蛋白衍生物及其合成。 在某些实施方案中，本发明的化合物表现出抗癌，抗病毒，抗生素和/或自身免疫治疗能力。 通常，本文公开的合成方法允许在多个位置引入各种取代基以及容易地引入β-内酯环部分。 在优选实施方案中，合成步骤包括串联的Mukaiyama醛醇内酯反应。 还公开了证明一些衍生物作为蛋白酶体抑制剂的效用的数据。

    NOVEL BELACTOSIN DERIVATIVES AS THERAPEUTIC AGENTS/BIOLOGICAL PROBES AND THEIR SYNTHESIS
    2.
    发明申请
    NOVEL BELACTOSIN DERIVATIVES AS THERAPEUTIC AGENTS/BIOLOGICAL PROBES AND THEIR SYNTHESIS 失效
    新型BELACTOSIN衍生物作为治疗药物/生物探针及其合成

    公开(公告)号：US20090042922A1

    公开(公告)日：2009-02-12

    申请号：US11775154

    申请日：2007-07-09

    申请人： Daniel Romo ,  Sung Wook Cho ,  Jeffrey W. Smith ,  Robyn D. Richardson

    发明人： Daniel Romo ,  Sung Wook Cho ,  Jeffrey W. Smith ,  Robyn D. Richardson

    IPC分类号： A61K31/365 ,  C07D305/08 ,  A61K31/4375 ,  A61P35/00 ,  C07D491/16

    CPC分类号： C07D407/12 ,  C07D305/12

    摘要： Derivatives of belactosin and their synthesis are disclosed. In certain embodiments, compounds of the present invention exhibit anti-cancer, antiviral, antibiotic, and/or auto-immune therapeutic abilities. In general, methods of synthesis disclosed herein allow for introduction of a variety of substituents at numerous positions as well as the facile introduction of a beta-lactone ring moiety. The synthetic steps comprise, in preferred embodiments, a tandem Mukaiyama aldol lactonization reaction. Data demonstrating the utility of some of the derivatives as proteasome inhibitors is also disclosed.

    摘要翻译： 披露了双乳糖蛋白衍生物及其合成。 在某些实施方案中，本发明的化合物表现出抗癌，抗病毒，抗生素和/或自身免疫治疗能力。 通常，本文公开的合成方法允许在多个位置引入各种取代基以及容易地引入β-内酯环部分。 在优选实施方案中，合成步骤包括串联的Mukaiyama醛醇内酯反应。 还公开了证明一些衍生物作为蛋白酶体抑制剂的效用的数据。

    Non contact measuring method for three dimensional micro pattern in measuring object
    5.
    发明授权
    Non contact measuring method for three dimensional micro pattern in measuring object 失效
    测量对象中三维微图案的非接触式测量方法

    公开(公告)号：US06005669A

    公开(公告)日：1999-12-21

    申请号：US65493

    申请日：1998-04-24

    申请人： Heui Jae Pahk ,  Sung Wook Cho ,  Woo Jung Ahn

    发明人： Heui Jae Pahk ,  Sung Wook Cho ,  Woo Jung Ahn

    IPC分类号： G01B11/30 ,  G01B11/02 ,  G01B11/06 ,  G01B11/24 ,  G01B11/00

    CPC分类号： G01B11/0608 ,  G01B11/02

    摘要： A non-contacting measuring method for three dimensional micro pattern in a measuring object is disclosed. Three dimensional micro pattern of the surface of the measuring object is measured using blur of light. For measurement, a mechanism of an optical window with a slit is inserted between light source and the measuring object. The blurred image is captured by charge coupled device sensor based image frame grabber, and is analyzed in personal computers. All the values of the relative height differences are obtained in overall scanning measurement area of the measuring object. The relative height differences are the distances from the reference position to the other positions. The reference position is selected when its image is sharp in focus on the screen. At this time, images of the other positions except the reference position are blurred out of focus on the screen. Also, from the law of geometric optics and the geometric similarity of triangles, the relation equation between the height difference and the ratio of blurred image size to sharp image size can be constructed. When the size of the image of the reference position and the sizes of the images with the blurred image of the other positions are measured, all the height differences between the reference position and the other position can be calculated if the coefficients of the relation equation are evaluated.

    摘要翻译： 公开了一种用于测量对象中的三维微图案的非接触测量方法。 使用模糊的光来测量测量对象的表面的三维微图案。 为了测量，在光源和测量对象之间插入具有狭缝的光学窗口的机构。 模糊图像通过基于电荷耦合器件传感器的图像帧获取器捕获，并在个人计算机中进行分析。 在测量对象的整个扫描测量区域中获得相对高差的所有值。 相对高度差是从参考位置到其他位置的距离。 当其图像在屏幕上焦点清晰时，选择参考点。 此时，除了参考位置之外的其他位置的图像在屏幕上失焦。 另外，从几何光学定律和三角形的几何相似度可以看出，高差与模糊图像尺寸与图像大小之间的关系方程可以被构建。 当测量参考位置的图像的大小和具有其他位置的模糊图像的图像的尺寸时，如果关系式的系数为 评估。

    Reverse modeling method using mesh data as feature
    6.
    发明申请
    Reverse modeling method using mesh data as feature 审中-公开
    使用网格数据作为特征的反向建模方法

    公开(公告)号：US20070285425A1

    公开(公告)日：2007-12-13

    申请号：US11595136

    申请日：2006-11-10

    申请人： Seock Hoon Bae ,  Dong Hoon Lee ,  Sung Wook Cho ,  Dong Hwa Kang ,  Joon Ho Seo

    发明人： Seock Hoon Bae ,  Dong Hoon Lee ,  Sung Wook Cho ,  Dong Hwa Kang ,  Joon Ho Seo

    IPC分类号： G06T15/20

    CPC分类号： G06F17/50

    摘要： A reverse modeling method using mesh data as a feature to allow reverse modeling to be conducted by following a procedure of an original designer includes the steps of detecting optional model data, setting the model data as a feature, and establishing a reference coordinate system of set mesh data; establishing a work plane on which a sketch of the set mesh data can be projected; projecting section data of the mesh data on the work plane; dividing data projected on the work plane into feature segments depending upon curvature distributions, and producing divided segments as sketch data; and producing a three dimensional feature from the sketch data which corresponds to a shape of the mesh data, and storing the produced three dimensional feature as model data, wherein the produced sketch data and three dimensional feature are parametrically connected with each other.

    摘要翻译： 使用网格数据作为特征的反向建模方法，通过遵循原始设计者的过程来进行反向建模，包括检测可选模型数据，将模型数据设置为特征并建立参考坐标系的集合 网格数据; 建立一个工作平面，在其上可以投影设置的网格数据的草图; 在工作平面上投影网格数据的部分数据; 将投影在工作平面上的数据根据​​曲率分布划分为特征段，并将划分的段作为草图数据; 并且从对应于网格数据的形状的草图数据生成三维特征，并将生成的三维特征存储为模型数据，其中所生成的草图数据和三维特征彼此参数连接。

    Wall-mounted microwave oven
    7.
    发明授权
    Wall-mounted microwave oven 有权
    壁挂式微波炉

    公开(公告)号：US07129452B2

    公开(公告)日：2006-10-31

    申请号：US10917447

    申请日：2004-08-13

    申请人： Sung Wook Cho

    发明人： Sung Wook Cho

    IPC分类号： H05B6/80

    CPC分类号： H05B6/6429

    摘要： A wall-mounted microwave oven including a fixing member having an improved structure for fixing an oven body to a vertical wall. The wall-mounted microwave oven achieves a reduction in manufacturing costs and convenient and simple manufacturing, transporting and installing processes. The wall-mounted microwave oven also includes a sheet adapted to set an accurate mounting position for the fixing member, in which the sheet has a size corresponding to that of the oven body and is made of paper or a similar material. The fixing member is provided with fixing holes. The sheet is provided with fixing position marks indicating fixing positions where screws have to be fastened to the wall through respective fixing holes. The fixing member is also provided with hooks respectively engaged with hook holes formed at a lower end of the oven body.

    摘要翻译： 一种壁挂式微波炉，包括具有改进的结构的固定构件，用于将烤箱本体固定到垂直壁。 壁挂式微波炉降低了制造成本，方便简单的制造，运输和安装过程。 壁挂式微波炉还包括适于为固定构件设置精确安装位置的片材，其中片材具有与烤箱本体相对应的尺寸并且由纸或类似材料制成。 固定构件设有固定孔。 该片材具有固定位置标记，指示固定位置，其中螺钉必须通过相应的固定孔紧固到壁上。 固定构件还设置有分别与形成在炉体下端的钩孔接合的钩。

    METHOD FOR PREPARING MICROTUBULAR HALLOYSITE NANOPOWDERS
    8.
    发明申请
    METHOD FOR PREPARING MICROTUBULAR HALLOYSITE NANOPOWDERS 有权
    制备微球纳米ZnO纳米粒子的方法

    公开(公告)号：US20120107214A1

    公开(公告)日：2012-05-03

    申请号：US12954878

    申请日：2010-11-28

    申请人： Yong Jae SUH ,  Young Mi Heo ,  Dae Sup Kil ,  Sung Wook Cho

    发明人： Yong Jae SUH ,  Young Mi Heo ,  Dae Sup Kil ,  Sung Wook Cho

    IPC分类号： C01B33/26 ,  B82Y40/00 ,  B82Y30/00

    CPC分类号： C01B33/26 ,  A61K8/0245 ,  A61K8/26 ,  A61K2800/10 ,  A61K2800/413 ,  A61Q19/00 ,  B82Y30/00 ,  C01P2004/13

    摘要： The present invention provides a method for preparing microtubular halloysite nanopowders by cutting halloysite nanotubes at a high pressure, microtubular halloysite nanopowders prepared by the method, and a cosmetic composition comprising the microtubular halloysite nanopowders. According to the method of the present invention, it is possible to prepare the halloysite nanopowders with a tubular shape using natural halloysite and effectively select a halloysite nanopowder having a desired shape. The microtubular halloysite nanopowders can be used in many industrial fields and used as a container or a carrier for nanoparticles or organic materials such as drugs, air fresheners, cosmetics, agricultural chemical materials, etc.

    摘要翻译： 本发明提供了一种通过高压切割多水高岭土纳米管制备微管多水高岭土纳米粉末的方法，该方法制备的微管多水高岭土纳米粉末和包含微管多水高岭土纳米粉末的化妆品组合物。 根据本发明的方法，可以使用天然多水高岭土制备具有管状形状的多水高岭土纳米粉末，并有效地选择具有所需形状的多水高岭土纳米粉末。 微管多壁高岭土纳米粉末可用于许多工业领域，用作纳米颗粒或有机材料如药物，空气清新剂，化妆品，农药等的容器或载体。

    Method for preparing microtubular halloysite nanopowders
    9.
    发明授权
    Method for preparing microtubular halloysite nanopowders 有权
    制备微管多水高岭土纳米粉体的方法

    公开(公告)号：US08540957B2

    公开(公告)日：2013-09-24

    申请号：US12954878

    申请日：2010-11-28

    申请人： Yong Jae Suh ,  Young Mi Heo ,  Dae Sup Kil ,  Sung Wook Cho

    发明人： Yong Jae Suh ,  Young Mi Heo ,  Dae Sup Kil ,  Sung Wook Cho

    IPC分类号： C01B33/26

    CPC分类号： C01B33/26 ,  A61K8/0245 ,  A61K8/26 ,  A61K2800/10 ,  A61K2800/413 ,  A61Q19/00 ,  B82Y30/00 ,  C01P2004/13

    摘要： The present invention provides a method for preparing microtubular halloysite nanopowders by cutting halloysite nanotubes at a high pressure, microtubular halloysite nanopowders prepared by the method, and a cosmetic composition comprising the microtubular halloysite nanopowders. According to the method of the present invention, it is possible to prepare the halloysite nanopowders with a tubular shape using natural halloysite and effectively select a halloysite nanopowder having a desired shape. The microtubular halloysite nanopowders can be used in many industrial fields and used as a container or a carrier for nanoparticles or organic materials such as drugs, air fresheners, cosmetics, agricultural chemical materials, etc.

    摘要翻译： 本发明提供了一种通过高压切割多水高岭土纳米管制备微管多水高岭土纳米粉末的方法，该方法制备的微管多水高岭土纳米粉末和包含微管多水高岭土纳米粉末的化妆品组合物。 根据本发明的方法，可以使用天然多水高岭土制备具有管状形状的多水高岭土纳米粉末，并有效地选择具有所需形状的多水高岭土纳米粉末。 微管多壁高岭土纳米粉末可用于许多工业领域，用作纳米颗粒或有机材料如药物，空气清新剂，化妆品，农药等的容器或载体。

    Microwave oven
    10.
    发明授权
    Microwave oven 有权
    微波炉

    公开(公告)号：US07271373B2

    公开(公告)日：2007-09-18

    申请号：US11108649

    申请日：2005-04-19

    申请人： Keun Seuk Oh ,  Sung Wook Cho

    发明人： Keun Seuk Oh ,  Sung Wook Cho

    IPC分类号： H05B6/72

    CPC分类号： H05B6/6473

    摘要： A microwave oven having a cooking chamber, at least one heat outlet provided in a sidewall of the cooking chamber, at least one heat inlet provided in the center of the sidewall of the cooking chamber, and a convection assembly. The convection assembly is disposed on an external side of the sidewall of the cooking chamber, and includes a fan, a heating element, and at least one guide bracket which guides heat from the heating element through the at least one heat outlet and into the cooking chamber. According to this configuration, a microwave oven heats food more evenly and efficiently.

    摘要翻译： 一种具有烹饪室的微波炉，设置在烹饪室的侧壁中的至少一个热出口，设置在烹饪室的侧壁中心的至少一个热入口和对流组件。 对流组件设置在烹饪室的侧壁的外侧，并且包括风扇，加热元件和至少一个引导支架，其引导来自加热元件的热​​量通过至少一个热出口并进入烹饪 房间。 根据该结构，微波炉能够均匀且高效地加热食物。