利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

36 条记录 (耗时 0.041 秒)

    Planar recording head having formed yokes
    1.
    发明授权
    Planar recording head having formed yokes 失效
    具有形成磁轭的平面记录头

    公开(公告)号：US6008969A

    公开(公告)日：1999-12-28

    申请号：US993719

    申请日：1997-12-18

    申请人： Darren T. Imai ,  David D. Roberts ,  Dimitre A. Latev ,  William C. Cain

    发明人： Darren T. Imai ,  David D. Roberts ,  Dimitre A. Latev ,  William C. Cain

    IPC分类号： G11B5/31 ,  G11B5/60

    CPC分类号： G11B5/3183 ,  G11B5/3163

    摘要： A planar thin film magnetic head comprises an insulating substrate, a pair of insulating pedestals formed on the substrate, a top magnetic yoke having a central portion disposed over the substrate and having opposite ends supported on each of the pedestals. A conductor is provided over the top yoke central portion, and an insulating layer is disposed between the conductor and the top magnetic yoke. A bottom magnetic yoke is disposed over the conductor and has a gap in a central portion and opposite ends in contact with the top yoke ends.

    摘要翻译： 平面薄膜磁头包括绝缘基板，形成在基板上的一对绝缘基座，顶部磁轭，其中心部分设置在基板上并具有支撑在每个基座上的相对端部。 导体设置在顶部磁轭中心部分之上，绝缘层设置在导体和顶部磁轭之间。 底部磁轭设置在导体上方，并且在中心部分具有间隙，并且相对端部与顶部磁轭端部接触。

    Planar magnetic ring head for contact recording with a rigid disk
    2.
    发明授权
    Planar magnetic ring head for contact recording with a rigid disk 失效
    平面磁环头，用于与刚性盘接触记录

    公开(公告)号：US06493191B1

    公开(公告)日：2002-12-10

    申请号：US08528890

    申请日：1995-09-15

    申请人： William C. Cain ,  Richard D. Anderson ,  Michael A. Baldwinson ,  Keith R. Berding ,  Michael E. Devillier ,  Garrett A. Garrettson ,  Randolph S. Gluck ,  Harold J. Hamilton ,  Robert D. Hempstead ,  Darren T. Imai ,  Kwang K. Kim ,  Dimitre A. Latev ,  Alexander P. Payne ,  David D. Roberts

    发明人： William C. Cain ,  Richard D. Anderson ,  Michael A. Baldwinson ,  Keith R. Berding ,  Michael E. Devillier ,  Garrett A. Garrettson ,  Randolph S. Gluck ,  Harold J. Hamilton ,  Robert D. Hempstead ,  Darren T. Imai ,  Kwang K. Kim ,  Dimitre A. Latev ,  Alexander P. Payne ,  David D. Roberts

    IPC分类号： G11B5187

    CPC分类号： G11B5/3163 ,  G11B5/3106 ,  G11B5/3183

    摘要： A transducer for a hard disk drive system has a planar magnetic core and a pair of poletips that project transversely from the core for sliding contact with the disk during reading and writing. The transducer is formed entirely of thin films in the shape of a low profile table having three legs that slide on the disk, the poletips being exposed at a bottom of one of the legs for high resolution communication with the disk, the throat height of the poletips affording sufficient tolerance to allow for wear. The legs elevate the transducer from the disk sufficiently to minimize lifting by a thin air layer that moves with the spinning disk which, in combination with the small size of the thin film head allows a low load and a flexible beam and gimbal to hold the transducer to the disk. The transducer includes a loop shaped core of magnetic material that ends at the poletips, the core extending further parallel than perpendicular to the disk surface and preferably being formed of a plurality of slightly spaced ribbons of magnetic material in order to increase high frequency permeance. A high magnetic saturation layer may be formed adjoining the gap in at least the trailing poletip, in order to avoid saturation at the poletips during writing. The dimensions of the yoke adjacent to the poletips are also designed to avoid saturation at the poletips by saturating at a lower flux in the yoke than the poletips. The close relationship between the transducer and the media of the disk affords high density magnetic data storage and retrieval.

    摘要翻译： 用于硬盘驱动系统的换能器具有平面磁芯和一对从芯体横向突出的小纸片，用于在读写期间与盘滑动接触。 传感器完全由薄板形成，其具有在盘上滑动的三条腿的小型表，其中一条腿露出在一条腿的底部，用于与盘的高分辨率通信，喉部的高度 小腿提供足够的耐受性以允许磨损。 这些腿将传感器从盘上提升到足以最小化由旋转盘移动的薄空气层的提升，其与小尺寸的薄膜头允许低负载并且柔性梁和万向节保持换能器 到磁盘。 换能器包括磁性材料的环形磁芯，其在端部终止，芯体比垂直于磁盘表面进一步平行延伸，并且优选地由多个稍微间隔的磁性材料带形成，以便增加高频磁导率。 至少可以在至少尾部poletip中形成邻接间隙的高磁饱和层，以避免写入期间在poletips处的饱和。 靠近小翼片的轭的尺寸也被设计成通过在轭中的低通量饱和而不是poletips饱和。 传感器与磁盘介质之间的紧密关系提供了高密度的磁数据存储和检索。

    PEPTIDES AND THEIR UTILITY IN MODULATION OF BEHAVIOR OF CELLS EXPRESSING alpha3beta1 INTEGRINS
    7.
    发明申请
    PEPTIDES AND THEIR UTILITY IN MODULATION OF BEHAVIOR OF CELLS EXPRESSING alpha3beta1 INTEGRINS 有权
    肽及其在表达α3β1整合的细胞行为调节中的应用

    公开(公告)号：US20080249026A1

    公开(公告)日：2008-10-09

    申请号：US11466718

    申请日：2006-08-23

    申请人： David D. Roberts ,  Henry C. Krutzsch

    发明人： David D. Roberts ,  Henry C. Krutzsch

    IPC分类号： A61K38/10 ,  C07K5/00 ,  C07K7/06 ,  C07K7/08 ,  A61P35/00 ,  C12N5/00 ,  A61P9/00 ,  A61K38/07 ,  A61K38/08

    CPC分类号： C07K7/06 ,  A61K38/00

    摘要： The present invention relates to a peptide comprising the sequence R1-X1-X2-X3-X4-R2, wherein X1 is selected from the group consisting of N, Q, D and S; X2 is selected from the group consisting of V, I and L; X1 is selected from the group consisting of R and K; and X4 is selected from the group consisting of V, I, L and F; R1 is a hydrogen or a peptide of 1 to 6 amino acids, and acyl or an aryl group; and R2 is a peptide of 1 to 3 amino acids, a hydroxide or an amide. The invention also relates to partial or full retro-inverso peptides comprising the above sequences. The invention also relates to peptide-substrate combination comprising a substrate suitable for cell growth and the peptide of the invention, and to a vascular graft and an artificial blood vessel comprising the peptide-substrate combination. The invention also relates to a pharmaceutical composition and a peptide conjugate comprising the peptide of the invention. The invention also relates to a method of inhibiting adhesion of a cell expressing α3β1 integrin to an extracellular matrix, inhibiting α3β1-integrin-mediated cell motility, inhibiting α3β1-integrin mediated cell proliferation, promoting α3β1-integrin mediated cell proliferation and inhibiting angiogenesis utilizing the peptides of the invention.

    摘要翻译： 本发明涉及包含序列R 1 -X 1 -X 2 -X 3 -X 3的肽， X 4 -R 2，其中X 1选自N，Q，D和S; X 2选自V，I和L; X 1选自R和K; 并且X 4选自V，I，L和F; R 1是氢或1至6个氨基酸的肽，酰基或芳基; R 2是1至3个氨基酸的肽，氢氧化物或酰胺。 本发明还涉及包含上述序列的部分或全部逆转肽。 本发明还涉及包含适合于细胞生长的底物和本发明的肽的肽 - 底物组合以及包含肽 - 底物组合的血管移植物和人造血管。 本发明还涉及包含本发明的肽的药物组合物和肽缀合物。 本发明还涉及一种抑制细胞外基质表达α3β1整联蛋白的细胞粘附的方法，抑制α3β1， 整合素介导的细胞运动，抑制α3-β1整联蛋白介导的细胞增殖，促进α3β - 整合素介导的细胞增殖并利用本发明的肽抑制血管生成。