利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

12 条记录 (耗时 0.03 秒)

    CLINICIAN-CONTROLLED SEMI-AUTOMATED MEDICATION MANAGEMENT
    1.
    发明申请
    CLINICIAN-CONTROLLED SEMI-AUTOMATED MEDICATION MANAGEMENT 审中-公开
    临床控制的半自动药物管理

    公开(公告)号：US20090054754A1

    公开(公告)日：2009-02-26

    申请号：US12188205

    申请日：2008-08-08

    申请人： Dave McMahon ,  Mark Ries Robinson ,  Mike Borrello ,  Richard Thompson ,  Shonn Hendee

    发明人： Dave McMahon ,  Mark Ries Robinson ,  Mike Borrello ,  Richard Thompson ,  Shonn Hendee

    IPC分类号： A61B5/145 ,  A61M5/00

    CPC分类号： A61M5/1723 ,  A61M2005/14296 ,  A61M2230/201 ,  G06F19/3468

    摘要： The present invention is directed to methods and apparatuses of medication management based upon active authorization of medication infusion by a clinician that can provide for effective management of an analyte in a patient's blood, reducing the opportunities for human error common with current manual systems while still placing final control of the medication management with the human clinician. For example, a semi-automated glucose management system can measure the glucose level in a patient's blood, recommend infusion parameters to a clinician who can authorize an infusion of glucose or insulin, and infuse the glucose or insulin into the patient.

    摘要翻译： 本发明涉及药物治疗方法和装置，其基于临床医生的药物输注的主动授权，其可以提供对患者血液中的分析物的有效管理，减少与当前手动系统共同的人为错误的机会，同时仍然放置 最终控制用药管理与人体临床医师。 例如，半自动葡萄糖管理系统可以测量患者血液中的葡萄糖水平，向可以授权输注葡萄糖或胰岛素的临床医生推荐输注参数，并将葡萄糖或胰岛素注入患者体内。

    DETERMINATION OF BLOOD PUMP SYSTEM PERFORMANCE AND SAMPLE DILUTION USING A PROPERTY OF FLUID BEING TRANSPORTED
    3.
    发明申请
    DETERMINATION OF BLOOD PUMP SYSTEM PERFORMANCE AND SAMPLE DILUTION USING A PROPERTY OF FLUID BEING TRANSPORTED 审中-公开
    使用流体输送物质确定血液泵系统性能和样品浓度

    公开(公告)号：US20110060199A1

    公开(公告)日：2011-03-10

    申请号：US12884175

    申请日：2010-09-16

    申请人： Mark Ries Robinson ,  Mike Borrello ,  Richard P. Thompson ,  Stephen Vanslyke ,  Shonn Hendee ,  Greg Knipstein ,  Dan Welsh

    发明人： Mark Ries Robinson ,  Mike Borrello ,  Richard P. Thompson ,  Stephen Vanslyke ,  Shonn Hendee ,  Greg Knipstein ,  Dan Welsh

    IPC分类号： A61B5/157

    CPC分类号： A61B5/14557 ,  A61B5/14532 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150946 ,  A61B5/150961 ,  A61B5/150992 ,  A61B5/153 ,  A61B5/155 ,  A61B5/157 ,  A61M1/1692 ,  A61M1/34 ,  A61M1/341 ,  A61M1/3621 ,  A61M1/3639 ,  A61M1/3663 ,  A61M5/16831 ,  A61M2005/1404 ,  A61M2205/3306 ,  A61M2205/331 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3368 ,  A61M2230/201

    摘要： The use of an optical or other measurement in a blood access system enables the determination of a fluid sample appropriate for measurement on a real time basis. This information can be used to control the blood access system and related measurement processes. The determination can be based on, for example, at least one of: optical density, optical scatter, analyte level, temperature, the absolute level of any of the preceding, the stability of any of the preceding, the rate of change of any of the preceding, or the value of any of the preceding relative to another determination. The determination can be made using, for example, at least one of: electrochemical sensor, ion specific electrode, capacitance measurement, impedance measurement, inductance measurement, conductivity measurement, optical measurement, and ultrasound measurement. The present invention relates to determination of the quality of a biological sample in which determination of an analyte concentration is to be made, and various methods and apparatuses related thereto. An evaluation of sample quality can be made by monitoring the temporal changes in the sample properties or characteristics as the biological sample is procured or measured. The methods and apparatuses described herein can be used to evaluate the temporal characteristics of a sample during sample acquisition and/or during determination of the sample analyte or parameter of interest. The sample quality assurance methods and apparatuses described herein can thus be used to ensure that a valid sample has been procured by or presented to an instrument or measurement system for analyte determination, thereby preventing the measurement and reporting of analyte values for a sample that is unstable or otherwise non-representative of the biological system from which the sample was obtained.

    摘要翻译： 在血液存取系统中使用光学或其他测量能够实时地确定适于测量的流体样品。 该信息可用于控制血液存取系统和相关测量过程。 该测定可以基于例如光密度，光学散度，分析物水平，温度，前述任一项的绝对水平，前述任一项的稳定性，任何变化率 前一个或前一个相对于另一个确定的任何值的值。 可以使用例如电化学传感器，离子专用电极，电容测量，阻抗测量，电感测量，电导率测量，光学测量和超声测量中的至少一个来进行确定。 本发明涉及要进行测定分析物浓度的生物样品的质量的确定以及与其相关的各种方法和装置。 通过监测采购或测量生物样品的样品性质或特性的时间变化，可以对样品质量进行评估。 本文描述的方法和装置可以用于在样品获取期间和/或在样品分析物或感兴趣的参数的确定期间评估样品的时间特征。 因此，本文所述的样品质量保证方法和装置可以用于确保有效样品已经由用于分析物测定的仪器或测量系统获得或呈现给样品，从而防止对不稳定的样品的分析物值的测量和报告 或以其他方式代表获得样品的生物系统。

    Variable Sampling Interval for Blood Analyte Determinations
    4.
    发明申请
    Variable Sampling Interval for Blood Analyte Determinations 审中-公开
    血液分析物测定的可变取样间隔

    公开(公告)号：US20090054753A1

    公开(公告)日：2009-02-26

    申请号：US11842624

    申请日：2007-08-21

    申请人： Mark Ries Robinson ,  Mike Borrello ,  Dave McMahon

    发明人： Mark Ries Robinson ,  Mike Borrello ,  Dave McMahon

    IPC分类号： A61B5/00 ,  G01N33/50

    CPC分类号： A61B5/14503 ,  A61B5/14532 ,  G06F19/3456 ,  G16H40/63 ,  G16H50/20 ,  G16H50/50

    摘要： The present invention provides methods and apparatuses that can provide measurement of glucose with variable intervals between measurements, allowing more efficient measurement with greater patient safety. A method according to the present invention can comprise measuring the value of an analyte such as glucose at a first time; determining a second time from a patient condition, an environmental condition, or a combination thereof; then measuring the value of the analyte at the second time (where the second time can be expressed as an interval after the first time, an absolute time, or a time indicated when certain patient or environmental conditions, or both, are reached or detected). The second time can be determined, as an example, from a comparison of the analyte value at the first time with a threshold. The interval between the first time and the second time can be related to the difference between the analyte value at the first time and the threshold; e.g., the closer to the threshold, the closer the two measurement times. The invention can be used with automated measurement systems, allowing the system to determine measurement times and automatically make measurements at the determined times, reducing operator interaction and operator error.

    摘要翻译： 本发明提供了可以在测量之间提供可变间隔的葡萄糖测量的方法和装置，从而允许更有效的测量，从而提高患者的安全性。 根据本发明的方法可以包括在第一时间测量诸如葡萄糖的分析物的值; 从患者状况，环境状况或其组合确定第二次; 然后在第二时间测量分析物的值（其中第二次可以表示为第一次之后的间隔，绝对时间，或在达到或检测到某些患者或环境条件或两者时指示的时间） 。 作为示例，可以从第一次的分析物值与阈值的比较确定第二次。 第一时间和第二时间之间的间隔可以与第一时间的分析物值和阈值之间的差异相关; 例如越接近阈值，两个测量时间越接近。 本发明可以与自动测量系统一起使用，允许系统确定测量时间，并在确定的时间自动进行测量，减少操作人员的交互和操作者的错误。

    Detecting Cross-contamination in Blood Measurements with a Multilumen Catheter
    9.
    发明申请
    Detecting Cross-contamination in Blood Measurements with a Multilumen Catheter 审中-公开
    用多次导管检测血液测量中的交叉污染

    公开(公告)号：US20090048535A1

    公开(公告)日：2009-02-19

    申请号：US11860545

    申请日：2007-09-25

    申请人： Mark Ries Robinson ,  Mike Borrello ,  John O'Mahony ,  Richard Thompson ,  V. Gerald Grafe

    发明人： Mark Ries Robinson ,  Mike Borrello ,  John O'Mahony ,  Richard Thompson ,  V. Gerald Grafe

    IPC分类号： A61B5/155

    CPC分类号： A61B5/150961 ,  A61B5/14532 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/155 ,  A61B5/157

    摘要： The present invention comprises methods and apparatuses that can provide accurate measurement of glucose or other analytes from a multilumen catheter in the presence of infusion of substances, including glucose. Examples of “multilumen catheters” include central venous catheters having multiple lumens, midline catheters having multiple lumens, multiple catheters configured or emplaced such that their lumens are in proximity to each other, and, in the case of indwelling analyte sensors, a catheter with a lumen for infusion and an indwelling sensor spaced apart from the infusion lumen. For blood withdrawal, anti-cross contamination controls can prevent the entrainment of blood which might be contaminated with feeding fluids or medications that are administered through other lumens within the catheter and in proximity of the blood sampling port. Cross contamination can occur under various situations, and is known to occur when the patient is connected to a ventilator. The ventilator cyclically raises the intra-thoracic pressure and diminishes blood flow rate in the central veins returning to the heart. The diminished flow can increase the chances for cross-contamination when additional lumens are introducing fluids during a draw sample.

    摘要翻译： 本发明包括在存在输入物质（包括葡萄糖）的情况下可以提供来自多腔导管的葡萄糖或其它分析物的精确测量的方法和装置。 “多腔导管”的实例包括具有多个内腔的中心静脉导管，具有多个腔的中线导管，多个导管被配置或放置成使得它们的内腔彼此靠近，并且在留置分析物传感器的情况下， 用于输注的内腔和与输液腔间隔开的留置传感器。 为了取血，反交叉污染控制可以防止可能被导管内和在血液采样端口附近通过其他管腔给药液体或药物而被污染的血液夹带。 交叉污染可以在各种情况下发生，并且已知当患者连接到通气机时发生交叉污染。 呼吸机周期性地升高胸腔内压，并减少返回心脏的中央静脉血流量。 减少的流量可以增加在抽取样品期间附加管腔引入流体时交叉污染的机会。

    Managing Cross-contamination in Blood Samples Withdrawn from a Multilumen Catheter
    10.
    发明申请
    Managing Cross-contamination in Blood Samples Withdrawn from a Multilumen Catheter 审中-公开
    管理从多次导管撤回的血液样本中的交叉污染

    公开(公告)号：US20090048576A1

    公开(公告)日：2009-02-19

    申请号：US11860544

    申请日：2007-09-25

    申请人： Mark Ries Robinson ,  Mike Borrello ,  John O'Mahony ,  Richard Thompson ,  Dave Tobler ,  V. Gerald Grafe

    发明人： Mark Ries Robinson ,  Mike Borrello ,  John O'Mahony ,  Richard Thompson ,  Dave Tobler ,  V. Gerald Grafe

    IPC分类号： A61M25/01

    CPC分类号： A61B5/150961 ,  A61B5/14532 ,  A61B5/15003 ,  A61B5/150213 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/155 ,  A61B5/157

    摘要： The present invention comprises methods and apparatuses that can provide accurate measurement of glucose or other analytes from a multilumen catheter in the presence of infusion of substances, including glucose. Examples of “multilumen catheters” include central venous catheters having multiple lumens, midline catheters having multiple lumens, multiple catheters configured or emplaced such that their lumens are in proximity to each other, and, in the case of indwelling analyte sensors, a catheter with a lumen for infusion and an indwelling sensor spaced apart from the infusion lumen. For blood withdrawal, anti-cross contamination controls can prevent the entrainment of blood which might be contaminated with feeding fluids or medications that are administered through other lumens within the catheter and in proximity of the blood sampling port. Cross contamination can occur under various situations, and is known to occur when the patient is connected to a ventilator. The ventilator cyclically raises the intra-thoracic pressure and diminishes blood flow rate in the central veins returning to the heart. The diminished flow can increase the chances for cross-contamination when additional lumens are introducing fluids during a draw sample.

    摘要翻译： 本发明包括在存在输入物质（包括葡萄糖）的情况下可以提供来自多腔导管的葡萄糖或其它分析物的精确测量的方法和装置。 “多腔导管”的实例包括具有多个腔的中心静脉导管，具有多个腔的中线导管，配置或放置多个导管，使得它们的内腔彼此靠近，并且在留置分析物传感器的情况下， 用于输注的内腔和与输液腔间隔开的留置传感器。 为了取血，反交叉污染控制可以防止可能被导管内和在血液采样端口附近通过其他管腔给药液体或药物而被污染的血液夹带。 交叉污染可以在各种情况下发生，并且已知当患者连接到通气机时发生交叉污染。 呼吸机周期性地升高胸腔内压，并减少返回心脏的中央静脉血流量。 减少的流量可以增加在抽取样品期间附加管腔引入流体时交叉污染的机会。