摘要:
A novel method for estimating the end-systolic pressure-volume relationship (ESPVR) is presented. The method provides for accurate estimation of the ESPVR from a single beat of the cardiac cycle. The method is based on normalized human time varying elastance curves [E.sub.N (t.sub.N)]. The ESPVR is estimated from one beat using PV data measured at normalized time t.sub.N and end-systole (t.sub.max) to predict intercept: ##EQU1## and slope: E.sub.max(SB) =P(t.sub.max)/[V(t.sub.max)-V.sub.0(SB) ]. The present invention provides a method for ESPVR estimation which is non-invasive and particularly applicable for bedside applications.
摘要:
A method for detecting vascular sclerosis is revealed. Firstly set a cuff on a human hand. Then inflate the cuff and later deflate the cuff. Next measure a pressure of the cuff and generate a pressure sensing signal. Process the pressure sensing signal to generate a processed signal and convert the processed signal. Then calculate a systolic pressure and a diastolic pressure according to the converted processed signal and also obtain a vasodilation constant. Thus a hardening of blood vessels is detected according to the vasodilation constant.
摘要:
The present invention relates to a device and a method for estimating central systolic blood pressure based on oscillometric signals from brachial artery by the use of a pressure cuff.
摘要:
The present invention provides transcription factors associated with the hedgehog signaling pathway that are regulated by dephosphorylation by phosphatases. Hedgehog response elements (HRE) that interact with the dephosphorylated transcription factors are also provided as well as methods for identifying compounds that are phosphatase inhibitors. Methods of treating tumors in a subject by modulating the phosphorylation of the transcription factor are also included.