Gel deodorant compositions having reduced skin irritation
    1.
    发明授权
    Gel deodorant compositions having reduced skin irritation 失效
    具有降低皮肤刺激性的凝胶除臭剂组合物

    公开(公告)号:US06174521B1

    公开(公告)日:2001-01-16

    申请号:US09071100

    申请日:1998-05-01

    IPC分类号: A61K732

    摘要: Disclosed are gel deodorant compositions comprising (a) from about 0.001% to about 50% by weight of a deodorant active, fragrance, or combination thereof; (b) from about 0.01% to about 20% by weight of a gellant; (c) from about 5% to about 90% by weight of a polymeric alcohol having at least one free hydroxyl group and also having from about 2 to about 80 alkoxylate radicals wherein the alkoxylate radical contains from about 2 to about 6 carbon atoms; (d) from about 5% to about 89% by weight of a nonpolymeric alcohol having at least two free hydroxyl groups, and also having from about 4 to about 20 carbon atoms, wherein the weight ratio of the polymeric to nonpolymeric alcohol is from about 18:1 to about 1:5; (e) from zero percent to about 10% by weight of glycerin; and (f) from about 0.01% to about 89% by weight of water. Also disclosed is a method of controlling malodor associated with perspiration by topical application of any deodorant composition containing a select combination of triclosan and triclocarban. All of these compositions remain clear or translucent over extended periods of time, and provide little or no skin irritation in addition to improved cosmetic benefits such as dry feel, ease of application, emolliency, fragrance longevity, and no powdery residue.

    摘要翻译: 公开了凝胶除臭剂组合物,其包含(a)约0.001重量%至约50重量%的除臭剂活性物质,香料或其组合; (b)约0.01重量%至约20重量%的胶凝剂; (c)约5%至约90%重量的具有至少一个游离羟基并且还具有约2至约80个烷氧基化物基团的聚合醇,其中烷氧基化物基团含有约2至约6个碳原子; (d)约5%至约89%重量的具有至少两个游离羟基的非聚合醇,并且还具有约4-约20个碳原子,其中聚合物与非聚合醇的重量比为约 18:1〜1:5; (e)甘油的0至10重量%; 和(f)约0.01%至约89%重量的水。 还公开了通过局部施用含有三氯生和三氯沙坦的选择性组合的任何除臭剂组合物来控制与出汗相关的恶臭的方法。 所有这些组合物在延长的时间段内保持透明或半透明,并且除了改善的美观效果,例如干燥感觉,易于使用,润肤性,香味长寿命,并且没有粉末残留物之外,提供很少或没有皮肤刺激。

    Antiperspirant composition containing 1,2-hexanediol
    2.
    发明授权
    Antiperspirant composition containing 1,2-hexanediol 失效
    含有1,2-己二醇的止汗组合物

    公开(公告)号:US5968489A

    公开(公告)日:1999-10-19

    申请号:US71178

    申请日:1998-05-01

    CPC分类号: A61Q15/00 A61K8/345 A61K8/892

    摘要: The present invention is directed to antiperspirant compositions which comprise from about 0.1% to about 99.9% by weight of solubilized or solid antiperspirant active and from about 0.1% to about 99.9% by weight of a carrier which comprises 1,2-hexanediol, preferably in combination with a volatile silicone liquid carrier and dimethiconol as a coupling agent. The 1,2-hexanediol carrier is a highly effective coupling agent and is milder to the skin when applied topically to the axilla or other areas of the skin as compared to many other polyol-containing carriers. Preferred are antiperspirant compositions containing solubilized antiperspirant active.

    摘要翻译: 本发明涉及止汗组合物,其包含约0.1重量%至约99.9重量%的增溶或固体止汗活性剂和约0.1重量%至约99.9重量%的载体,其包含1,2-己二醇,优选在 与挥发性硅氧烷液体载体和聚二甲基硅氧烷醇作为偶联剂组合。 与许多其它含多元醇的载体相比,1,2-己二醇载体是高度有效的偶联剂,并且当局部施用于腋窝或皮肤的其它区域时对皮肤温和。 优选的是含有增溶止汗活性物质的止汗组合物。

    Anhydrous gel deodorant compositions
    3.
    发明授权
    Anhydrous gel deodorant compositions 失效
    无水凝胶除臭剂组合物

    公开(公告)号:US5902572A

    公开(公告)日:1999-05-11

    申请号:US71106

    申请日:1998-05-01

    摘要: Disclosed are anhydrous gel deodorant compositions comprising from about 0.001% to about 50% by weight of deodorant active, fragrance, or combination thereof, from about 0.01% to about 20% by weight of a gellant; from about 1% to about 50% by weight of a nonpolar volatile solvent having a solubility parameter of less than 8.0 (cal/cm.sup.3).sup.0.5, a vapor pressure of from about 0.01 mm Hg to about 6 mm Hg at 25.degree. C., and a boiling point at 1 atm of less than about 250.degree. C.; from about 1% to about 15% by weight of a polar solvent having a solubility parameter of from 12.5 (cal/cm.sup.3).sup.0.5 to about 25 (cal/cm.sup.3).sup.0.5 and optionally a moderately polar solvent having a solubility parameter of from about 8.0 (cal/cm.sup.3).sup.0.5 to less than 12.5 (cal/cm.sup.3).sup.0.5, preferably 1,2-hexanediol. Other preferred embodiments include those which contain combinations of triclosan and triclocarban for improved deodorant efficacy. These compositions provide improved performance and skin feel characteristics, and are especially effective at providing deodorant application which is milder to the skin, and improved product clarity.

    摘要翻译: 公开了无水凝胶除臭剂组合物,其包含约0.001重量%至约50重量%的除臭剂活性物质,香料或其组合,约0.01重量%至约20重量%的胶凝剂; 约1%至约50%重​​量的溶解度参数小于8.0(cal / cm 3)0.5的非极性挥发性溶剂,25℃下蒸气压为约0.01mmHg至约6mm Hg, 沸点在1atm小于约250℃。 约1%至约15%重量的溶度参数为12.5(cal / cm 3)0.5至约25(cal / cm 3)0.5的极性溶剂和任选的溶度参数为约8.0的中等极性溶剂 (cal / cm 3)0.5至小于12.5(cal / cm 3)0.5,优选1,2-己二醇。 其它优选的实施方案包括含有三氯生和三氯卡班组合以提高除臭功效的实施方案。 这些组合物提供改进的性能和皮肤感觉特性,并且特别有效地提供对皮肤温和的除臭剂应用,并提高产品透明度。

    Antiperspirant gel-solid stick composition containing a modified
silicone carrier
    4.
    发明授权
    Antiperspirant gel-solid stick composition containing a modified silicone carrier 失效
    含有改性硅酮载体的止汗凝胶固体棒组合物

    公开(公告)号:US5840288A

    公开(公告)日:1998-11-24

    申请号:US771614

    申请日:1996-12-20

    摘要: Disclosed are anhydrous antiperspirant gel-solid sticks which comprise particulate antiperspirant active; a solid non-polymeric gellant that is substantially free of dibenzylidene alditol, inorganic thickening agents, organic polymeric gellants, n-acyl amino acid derivatives, or combinations thereof; an anhydrous liquid carrier containing polyalkylsiloxanes, polyalkyarylsiloxanes, polyestersiloxanes, polyethersiloxane copolymers, polyfluorosiloxanes, polyaminosiloxanes, or combinations thereof. The composition has a visible residue index of from about 11 to about 30 L-value, a product hardness of from about 500 to about 5,000 gram.multidot.force, a rheology profile defined by a ratio of an elastic modulus (G') to a viscous modulus (G") of from about 0.1 to about 100. The refractive indices of the particulate antiperspirant active, the solid non-polymeric gellant, and the anhydrous liquid carrier are not matched. The compositions preferably comprise crystalline gellant particles having an average particle size of less than about 1 .mu.m and/or a particle morphology having an aspect ratio of greater than about 2. These compositions provide improved low residue performance, efficacy and aesthetics.

    摘要翻译: 公开了包含颗粒止汗活性剂的无水止汗凝胶固体棒; 基本上不含二亚苄基糖醇的固体非聚合物胶凝剂,无机增稠剂,有机聚合物胶凝剂,n-酰基氨基酸衍生物或其组合; 含有聚烷基硅氧烷,聚烷基芳基硅氧烷,聚酯硅氧烷,聚醚硅氧烷共聚物,聚氟硅氧烷,聚氨基硅氧烷或其组合的无水液体载体。 该组合物具有约11至约30L值的可见残留指数,约500至约5,000克力的产品硬度,由弹性模量(G')与粘性模量 G“)为约0.1至约100.颗粒止汗剂活性物质,固体非聚合物胶凝剂和无水液体载体的折射率不匹配。 组合物优选包含平均粒径小于约1μm的结晶胶凝剂颗粒和/或具有大于约2的纵横比的颗粒形态。这些组合物提供改善的低残留性能,功效和美观性。

    Deodorant compositions containing 1,2-hexanediol
    5.
    发明授权
    Deodorant compositions containing 1,2-hexanediol 失效
    含有1,2-己二醇的除臭剂组合物

    公开(公告)号:US6013248A

    公开(公告)日:2000-01-11

    申请号:US71179

    申请日:1998-05-01

    CPC分类号: A61Q15/00 A61K8/042 A61K8/345

    摘要: The present invention is directed to deodorant compositions, and methods of using such compositions, wherein the compositions comprise from about 0.1% to about 99.9% by weight of a deodorant active, fragrance or combination thereof, and from about 0.1% to about 99.9% by weight of a carrier comprising 1,2-hexanediol. The deodorant composition preferably further comprises a suitable gellant or structurant to provide the desired product form, including a deodorant gel solid stick. The 1,2-hexanediol carrier is a highly effective coupling agent and is milder to the skin when applied topically to the axilla or other areas of the skin as compared to many other polyol-containing deodorant compositions. The present invention also relates to the use of triclosan/triclocarban combinations for improved deodorant efficacy.

    摘要翻译: 本发明涉及除臭剂组合物和使用这些组合物的方法,其中组合物包含按重量计约0.1%至约99.9%的除臭剂活性物质,香料或其组合,以及约0.1%至约99.9% 包含1,2-己二醇的载体的重量。 除臭剂组合物优选还包含合适的胶凝剂或结构剂以提供所需产品形式,包括除臭凝胶固体棒。 与许多其它含多元醇的除臭剂组合物相比,1,2-己二醇载体是高度有效的偶联剂,并且当局部应用于腋窝或皮肤的其它区域时对皮肤温和。 本发明还涉及三氯生/三氯沙坦组合在改善除臭功效方面的用途。

    Antiperspirant gel-solid stick compositions substantially free of select
polar solvents
    6.
    发明授权
    Antiperspirant gel-solid stick compositions substantially free of select polar solvents 失效
    基本上不含选择的极性溶剂的止汗凝胶固体棒组合物

    公开(公告)号:US5744130A

    公开(公告)日:1998-04-28

    申请号:US770307

    申请日:1996-12-20

    摘要: Disclosed are anhydrous antiperspirant gel-solid sticks which comprise particulate antiperspirant active; a solid non-polymeric gellant that is substantially free of dibenzylidene alditol, inorganic thickening agents, organic polymeric gellants, amides and esters of N-acyl amino acid, or combinations thereof; an anhydrous liquid carrier that is substantially free of polar, water-immiscible, organic solvents, wherein the composition has a visible residue index of from about 11 to about 30 L-value, a product hardness of from about 500 to about 5,000 gram force, a rheology profile defined by a ratio of an elastic modulus (G') to a viscous modulus (G") of from about 0.1 to about 100. The refractive indices of the particulate antiperspirant active, the solid non-polymeric gellant, and the anhydrous liquid carrier are not matched. The compositions preferably comprise crystalline gellant particles having an average particle size of less than about 1 .mu.m and/or a particle morphology having an aspect ratio of greater than about 2. These compositions provide improved low residue performance, efficacy and aesthetics.

    摘要翻译: 公开了包含颗粒止汗活性剂的无水止汗凝胶固体棒; 基本上不含二亚苄基糖醇的固体非聚合物胶凝剂,无机增稠剂,有机聚合胶凝剂,N-酰基氨基酸的酰胺和酯,或其组合; 无水液体载体,其基本上不含极性的与水不混溶的有机溶剂,其中所述组合物具有约11至约30L值的可见残留指数,约500至约5,000克力的产品硬度, 由弹性模量(G')与粘性模量(G“)的比率约为0.1至约100的流变学特征定义。粒状止汗剂活性物质,固体非聚合胶凝剂和 无水液体载体不匹配。 组合物优选包含平均粒径小于约1μm的结晶胶凝剂颗粒和/或具有大于约2的纵横比的颗粒形态。这些组合物提供改善的低残留性能,功效和美观性。