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公开(公告)号：US20110288026A1
公开(公告)日：2011-11-24
申请号：US13052778
申请日：2011-03-21
申请人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
发明人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
CPC分类号： B29C67/0007 , A61F2/08 , A61K38/00 , A61K2035/126 , A61L15/32 , A61L27/18 , A61L27/24 , A61L27/26 , A61L27/34 , A61L27/3804 , A61L27/3839 , A61L27/3895 , A61L27/507 , A61L31/041 , A61L2430/30 , B29C41/006 , C07K14/78 , C12N5/0012 , C12N5/0068 , C12N2533/40 , C12N2533/54 , D01D5/0038 , D01F1/10 , D01F4/00 , Y10T428/298 , Y10T442/2525 , Y10T442/60 , Y10T442/614 , C08L67/04 , C08L89/00 , C08L89/06
摘要： The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
摘要翻译： 本发明涉及电加工胶原的形成和使用，包括用作细胞外基质，并与细胞一起用于形成工程化组织。 工程组织可以包括可以植入受体的特定器官或组织的合成制造。 电处理胶原蛋白也可以与其他分子组合，以将物质递送到电加工胶原的施用部位或植入。 将胶原或胶原/细胞悬浮液电沉积在基质上以形成组织和器官。
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公开(公告)号：US08586345B2
公开(公告)日：2013-11-19
申请号：US13052778
申请日：2011-03-21
申请人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
发明人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
CPC分类号： B29C67/0007 , A61F2/08 , A61K38/00 , A61K2035/126 , A61L15/32 , A61L27/18 , A61L27/24 , A61L27/26 , A61L27/34 , A61L27/3804 , A61L27/3839 , A61L27/3895 , A61L27/507 , A61L31/041 , A61L2430/30 , B29C41/006 , C07K14/78 , C12N5/0012 , C12N5/0068 , C12N2533/40 , C12N2533/54 , D01D5/0038 , D01F1/10 , D01F4/00 , Y10T428/298 , Y10T442/2525 , Y10T442/60 , Y10T442/614 , C08L67/04 , C08L89/00 , C08L89/06
摘要： The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
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公开(公告)号：US07615373B2
公开(公告)日：2009-11-10
申请号：US10447670
申请日：2003-05-28
申请人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
发明人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
CPC分类号： B29C67/0007 , A61F2/08 , A61K38/00 , A61K2035/126 , A61L15/32 , A61L27/18 , A61L27/24 , A61L27/26 , A61L27/34 , A61L27/3804 , A61L27/3839 , A61L27/3895 , A61L27/507 , A61L31/041 , A61L2430/30 , B29C41/006 , C07K14/78 , C12N5/0012 , C12N5/0068 , C12N2533/40 , C12N2533/54 , D01D5/0038 , D01F1/10 , D01F4/00 , Y10T428/298 , Y10T442/2525 , Y10T442/60 , Y10T442/614 , C08L67/04 , C08L89/00 , C08L89/06
摘要： The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
摘要翻译： 本发明涉及电加工胶原的形成和使用，包括用作细胞外基质，并与细胞一起用于形成工程化组织。 工程组织可以包括可以植入受体的特定器官或组织的合成制造。 电处理胶原蛋白也可以与其他分子组合，以将物质递送到电加工胶原的施用部位或植入。 将胶原或胶原/细胞悬浮液电沉积在基质上以形成组织和器官。
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