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公开(公告)号：US20110288026A1
公开(公告)日：2011-11-24
申请号：US13052778
申请日：2011-03-21
申请人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
发明人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
CPC分类号： B29C67/0007 , A61F2/08 , A61K38/00 , A61K2035/126 , A61L15/32 , A61L27/18 , A61L27/24 , A61L27/26 , A61L27/34 , A61L27/3804 , A61L27/3839 , A61L27/3895 , A61L27/507 , A61L31/041 , A61L2430/30 , B29C41/006 , C07K14/78 , C12N5/0012 , C12N5/0068 , C12N2533/40 , C12N2533/54 , D01D5/0038 , D01F1/10 , D01F4/00 , Y10T428/298 , Y10T442/2525 , Y10T442/60 , Y10T442/614 , C08L67/04 , C08L89/00 , C08L89/06
摘要： The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
摘要翻译： 本发明涉及电加工胶原的形成和使用，包括用作细胞外基质，并与细胞一起用于形成工程化组织。 工程组织可以包括可以植入受体的特定器官或组织的合成制造。 电处理胶原蛋白也可以与其他分子组合，以将物质递送到电加工胶原的施用部位或植入。 将胶原或胶原/细胞悬浮液电沉积在基质上以形成组织和器官。
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公开(公告)号：US08586345B2
公开(公告)日：2013-11-19
申请号：US13052778
申请日：2011-03-21
申请人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
发明人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
CPC分类号： B29C67/0007 , A61F2/08 , A61K38/00 , A61K2035/126 , A61L15/32 , A61L27/18 , A61L27/24 , A61L27/26 , A61L27/34 , A61L27/3804 , A61L27/3839 , A61L27/3895 , A61L27/507 , A61L31/041 , A61L2430/30 , B29C41/006 , C07K14/78 , C12N5/0012 , C12N5/0068 , C12N2533/40 , C12N2533/54 , D01D5/0038 , D01F1/10 , D01F4/00 , Y10T428/298 , Y10T442/2525 , Y10T442/60 , Y10T442/614 , C08L67/04 , C08L89/00 , C08L89/06
摘要： The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
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公开(公告)号：US07615373B2
公开(公告)日：2009-11-10
申请号：US10447670
申请日：2003-05-28
申请人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
发明人： David G. Simpson , Gary L. Bowlin , Gary E. Wnek , Peter J. Stevens , Marcus E. Carr , Jamil A. Matthews , Saravanamoorthy Rajendran
CPC分类号： B29C67/0007 , A61F2/08 , A61K38/00 , A61K2035/126 , A61L15/32 , A61L27/18 , A61L27/24 , A61L27/26 , A61L27/34 , A61L27/3804 , A61L27/3839 , A61L27/3895 , A61L27/507 , A61L31/041 , A61L2430/30 , B29C41/006 , C07K14/78 , C12N5/0012 , C12N5/0068 , C12N2533/40 , C12N2533/54 , D01D5/0038 , D01F1/10 , D01F4/00 , Y10T428/298 , Y10T442/2525 , Y10T442/60 , Y10T442/614 , C08L67/04 , C08L89/00 , C08L89/06
摘要： The invention is directed to formation and use of electroprocessed collagen, including use as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or tissues which may be implanted into a recipient. The electroprocessed collagen may also be combined with other molecules in order to deliver substances to the site of application or implantation of the electroprocessed collagen. The collagen or collagen/cell suspension is electrodeposited onto a substrate to form tissues and organs.
摘要翻译： 本发明涉及电加工胶原的形成和使用，包括用作细胞外基质，并与细胞一起用于形成工程化组织。 工程组织可以包括可以植入受体的特定器官或组织的合成制造。 电处理胶原蛋白也可以与其他分子组合，以将物质递送到电加工胶原的施用部位或植入。 将胶原或胶原/细胞悬浮液电沉积在基质上以形成组织和器官。
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公开(公告)号：US20100291058A1
公开(公告)日：2010-11-18
申请号：US12758360
申请日：2010-04-12
申请人： Gary L. Bowlin , David G. Simpson , Gary E. Wnek , Marcus E. Carr, JR. , Peter J. Stevens , Gary Cadd , I. Kelman Cohen
发明人： Gary L. Bowlin , David G. Simpson , Gary E. Wnek , Marcus E. Carr, JR. , Peter J. Stevens , Gary Cadd , I. Kelman Cohen
CPC分类号： A61L24/102 , A61F2/105 , A61F2013/00314 , A61F2013/00472 , A61K38/363 , A61K38/39 , A61L24/106 , C07K14/78 , Y10T428/298 , A61K2300/00
摘要： The present invention relates to sealants for skin and other tissues. The sealants include an electroprocessed material. The sealants may contain more than one electroprocessed materials and may contain additional substances. The invention further relates to methods of making and using such sealants.
摘要翻译： 本发明涉及用于皮肤和其它组织的密封剂。 密封剂包括电加工材料。 密封剂可能含有多于一种的电处理材料，并且可能含有其他物质。 本发明还涉及制造和使用这种密封剂的方法。
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公开(公告)号：US5833642A
公开(公告)日：1998-11-10
申请号：US825834
申请日：1997-04-04
申请人： John P. McCabe , Peter J. Stevens
发明人： John P. McCabe , Peter J. Stevens
IPC分类号： A61F13/00 , A61F13/02 , A61F13/15 , A61F13/20 , A61L15/24 , A61L15/28 , A61L26/00 , A61F15/00
CPC分类号： A61L26/0023 , A61F13/00021 , A61L15/24 , A61L15/28 , A61L26/0061 , A61F13/0269 , A61F13/2005 , A61F2013/00097 , A61F2013/00102 , A61F2013/00157 , A61F2013/00217 , A61F2013/00229 , A61F2013/00251 , A61F2013/00523 , A61F2013/00727 , A61F2013/00748 , A61F2013/00859 , A61F2013/00927 , A61F2013/51147
摘要： A product suitable for absorbing wound exudate comprising a series of interconnected square or rectangular perforated bags made of a substance of maximum thickness 1 mm e.g. film, which is substantially non-adherent to a wound, wherein alginic acid or a salt thereof such as calcium alginate is housed in the bags, preferably in the form of small spheres. The film preferably comprises ethylene/methyl acrylate copolymer. Alternatively, the product comprises a string along which beads of alginic acid or alginate are threaded.
摘要翻译： 适用于吸收伤口渗出液的产品，包括由最大厚度为1mm的物质制成的一系列互连的方形或矩形穿孔袋，例如 膜，其基本上不附着于伤口，其中海藻酸或其盐如海藻酸钙被容纳在袋中，优选为小球形。 该膜优选包含乙烯/丙烯酸甲酯共聚物。 或者，产品包括一串串海藻酸或藻酸盐珠沿着该绳线。
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