专利检索 ap:("David George Allen" OR "Chuen Chan" OR "Caroline Mary Cook" OR "Richard Peter Charles Cousins" OR "Brian Cox" OR "Hazel Joan Dyke" OR "Frank Ellis" OR "Joanna Victoria Geden" OR "Heather Hobbs" OR "Suzanne Elaine Keeling" OR "Alison Judith Redgrave" OR "Stephen Swanson" OR "Caroline Whitworth" OR "David Bays") AND inv:"David Bays" 第 1 页

1.

发明授权
2-(purin-9-yl)-Tetrahydrofuran-3,4-diol derivatives 失效
标题翻译： 2-（嘌呤-9-基） - 四氢呋喃-3,4-二醇衍生物

公开(公告)号：US06534486B1

公开(公告)日：2003-03-18

申请号：US09720193

申请日：2001-02-28

申请人： David George Allen , Chuen Chan , Caroline Mary Cook , Richard Peter Charles Cousins , Brian Cox , Hazel Joan Dyke , Frank Ellis , Joanna Victoria Geden , Heather Hobbs , Suzanne Elaine Keeling , Alison Judith Redgrave , Stephen Swanson , Caroline Whitworth , David Bays

发明人： David George Allen , Chuen Chan , Caroline Mary Cook , Richard Peter Charles Cousins , Brian Cox , Hazel Joan Dyke , Frank Ellis , Joanna Victoria Geden , Heather Hobbs , Suzanne Elaine Keeling , Alison Judith Redgrave , Stephen Swanson , Caroline Whitworth , David Bays

IPC分类号： A01N4304

CPC分类号： C07H19/16 , Y10S514/826 , Y10S514/851 , Y10S514/921 , Y10S514/925

摘要： A series of 2-(Purin-9-yl)-tetrahydrofuran-3,4-diol derivatives with broad anti-inflammatory properties which inhibit leukocyte recruitment and activation and which are agonists of the adenosine 2a receptor are described.

摘要翻译： 描述了一系列具有抑制白细胞募集和活化并且是腺苷2a受体激动剂的广泛抗炎性质的2-（嘌呤-9-基） - 四氢呋喃-3,4-二醇衍生物。

2.

发明授权
Heterocyclic derivatives 失效
标题翻译：杂环衍生物

公开(公告)号：US4585781A

公开(公告)日：1986-04-29

申请号：US567005

申请日：1983-12-30

申请人： David Bays , Roger Hayes , Philip Blatcher

发明人： David Bays , Roger Hayes , Philip Blatcher

IPC分类号： C07D257/04 , C07D405/12 , C07D417/12 , C07D403/12 , A61K31/415 , A61K31/425

CPC分类号： C07D257/04 , C07D405/12 , C07D417/12

摘要： This invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts and hydrates thereof, in which R.sub.1 represents a hydrogen atom or an alkyl, alkanoyl, aroyl or trifluoroalkyl group;R.sub.2 represents a hydrogen atom or an alkyl or alkenyl group or C.sub.2-6 alkyl group substituted by a hydroxy or alkoxy group;X represents a sulphur atom or NH;Y represents an oxygen or sulphur atom or a bond;m represents 1, 2 or 3; andn represents 2, 3 or 4.The compounds show pharmacological activity as selective histamine H.sub.2 -antagonists.

摘要翻译： 本发明涉及通式（I）的化合物及其生理学上可接受的盐和水合物，其中R 1表示氢原子或烷基，烷酰基，芳酰基或三氟烷基; R2表示氢原子或被羟基或烷氧基取代的烷基或烯基或C2-6烷基; X表示硫原子或NH; Y表示氧或硫原子或键; m表示1,2或3; 并且n表示2,3或4.化合物显示作为选择性组胺H2拮抗剂的药理活性。