公开(公告)号：US20070176982A1

公开(公告)日：2007-08-02

申请号：US11345092

申请日：2006-02-01

申请人： David King ,  George Parish ,  James Powers ,  Lucas Barkley

发明人： David King ,  George Parish ,  James Powers ,  Lucas Barkley

IPC分类号： B41J2/175

CPC分类号： B41J2/1753 ,  B41J2/14145 ,  B41J2202/11

摘要： Inkjet printheads and actuator chips, such as an inkjet printhead actuator chip having a substrate, ink vias formed in the substrate, and columnar arrays of actuators in operational communication with the ink vias. At least one of the ink vias has at least one of a different length, width and a via to via pitch than another one of the ink vias. Imaging devices for use with the printheads are also disclosed.

摘要翻译： 喷墨打印头和致动器芯片，例如具有基板的喷墨打印头致动器芯片，形成在基板中的油墨通孔和与油墨通孔操作连通的致动器柱状阵列。 油墨通孔中的至少一个具有与另一个墨通孔不同的长度，宽度和通孔间距中的至少一个。 还公开了与打印头一起使用的成像装置。

公开(公告)号：US20070091136A1

公开(公告)日：2007-04-26

申请号：US11254456

申请日：2005-10-20

申请人： Lucas Barkley ,  David King ,  Randall Mayo ,  George Parish

发明人： Lucas Barkley ,  David King ,  Randall Mayo ,  George Parish

IPC分类号： B41J29/393

CPC分类号： B41J19/145 ,  B41J2/2132 ,  G06K15/107

摘要： Printheads configured to operate in accordance with a plurality of print modes. For example, one of the plurality of print modes can be selected in accordance with a bit of address data received by the printhead. In an exemplary embodiment, the selection of print mode can be accomplished by switching one or more actuator (e.g., heater) circuit addresses on the printhead.

摘要翻译： 打印头被配置为根据多种打印模式进行操作。 例如，可以根据由打印头接收到的地址数据的位来选择多个打印模式之一。 在示例性实施例中，可以通过切换打印头上的一个或多个致动器（例如，加热器）电路地址来实现打印模式的选择。

公开(公告)号：US20070153044A1

公开(公告)日：2007-07-05

申请号：US11323809

申请日：2005-12-30

申请人： Lucas Barkley ,  Bruce Gibson ,  Eric Hall ,  David King ,  George Parish

发明人： Lucas Barkley ,  Bruce Gibson ,  Eric Hall ,  David King ,  George Parish

IPC分类号： B41J29/38

CPC分类号： B41J2/195 ,  B41J2/04563 ,  B41J2/0458

摘要： Heater chips for use with a printing device, such as heater chips that include a first heater array, positioned substantially adjacent a first via, and a second heater array, positioned substantially adjacent a second via. The heater chip can also include a region, positioned between the first heater array and the second heater array, and a temperature sensing element operable to sense the temperature of the region, where the temperature sensing element is substantially centrally disposed with respect to the region. According to one embodiment of the invention, the temperature sensing element comprises a temperature sensing resistor.

摘要翻译： 用于与打印装置一起使用的加热器芯片，例如包括基本上邻近第一通孔定位的第一加热器阵列的加热器芯片和基本上邻近第二通孔定位的第二加热器阵列。 加热器芯片还可以包括位于第一加热器阵列和第二加热器阵列之间的区域，以及温度感测元件，其可操作以感测区域的温度，其中温度感测元件相对于该区域基本上居中设置。 根据本发明的一个实施例，温度感测元件包括温度感测电阻器。

公开(公告)号：US20070153045A1

公开(公告)日：2007-07-05

申请号：US11324167

申请日：2005-12-30

申请人： Lucas Barkley ,  Bruce Gibson ,  Eric Hall ,  David King ,  George Parish

发明人： Lucas Barkley ,  Bruce Gibson ,  Eric Hall ,  David King ,  George Parish

IPC分类号： B41J29/38

CPC分类号： B41J2/195 ,  B41J2/04563 ,  B41J2/0458

摘要： Heater chips for use with a printing device, such as heater chips that include a first heater array, positioned substantially adjacent a first via, and a second heater array, positioned substantially adjacent a second via. The heater chip can also include a region, positioned between the first heater array and the second heater array, and a temperature sensing element operable to sense the temperature of the region, where the temperature sensing element is substantially centrally disposed with respect to the region. Additionally, the first heater array and the second heater array are operable to receive heating responsive to the temperature of the region sensed by the temperature sensing element to regulate the temperature of the region. According to one embodiment of the invention, the temperature sensing element comprises a temperature sensing resistor and the heating may occur via non-nucleating heating.

摘要翻译： 用于与打印装置一起使用的加热器芯片，例如包括基本上邻近第一通孔定位的第一加热器阵列的加热器芯片和基本上邻近第二通孔定位的第二加热器阵列。 加热器芯片还可以包括位于第一加热器阵列和第二加热器阵列之间的区域，以及温度感测元件，其可操作以感测区域的温度，其中温度感测元件相对于该区域基本上居中设置。 另外，第一加热器阵列和第二加热器阵列可操作以响应于由温度感测元件感测的区域的温度接收加热，以调节该区域的温度。 根据本发明的一个实施例，温度感测元件包括温度感测电阻器，并且加热可以通过非成核加热发生。

公开(公告)号：US20060232627A1

公开(公告)日：2006-10-19

申请号：US11095965

申请日：2005-03-31

申请人： David King ,  George Parish ,  Kristi Rowe

发明人： David King ,  George Parish ,  Kristi Rowe

IPC分类号： B41J2/14

CPC分类号： B41J2/14072

摘要： An ejector chip (e.g., a heater chip) has at least one fluid (e.g., ink) via, and an elongated actuator (e.g., a resistive heating element) between an edge of the chip and the via. The chip also has a conductive trace connected to the actuator. The chip also has a bondpad central to the length of the actuator to reduce a length of the conductive trace.

摘要翻译： 喷射器芯片（例如，加热器芯片）在芯片的边缘和通孔之间具有至少一个流体（例如墨水）通孔和细长致动器（例如，电阻加热元件）。 该芯片还具有连接到执行器的导电迹线。 该芯片还具有对致动器长度的中心的接合垫，以减少导电迹线的长度。

公开(公告)号：US10779515B1

公开(公告)日：2020-09-22

申请号：US16007159

申请日：2018-06-13

申请人： David King ,  Ray Stewart

发明人： David King ,  Ray Stewart

IPC分类号： A01K61/00 ,  A01K61/78 ,  F16B9/00 ,  A01K61/10

摘要： The present invention is an anchor for an artificial structure for attracting fish within a body of water. The structure is comprised of a base and has a central attachment post, a central column configured to secure to the attachment post, and a protective plate.

公开(公告)号：US20130202591A1

公开(公告)日：2013-08-08

申请号：US13814262

申请日：2011-08-02

申请人： Robert Horlick ,  David King ,  Peter Bowers ,  Jennifer Dalton ,  Betty Wu ,  Traci Roberts ,  Xue Zhang ,  Laurence Altobell, III

发明人： Robert Horlick ,  David King ,  Peter Bowers ,  Jennifer Dalton ,  Betty Wu ,  Traci Roberts ,  Xue Zhang ,  Laurence Altobell, III

IPC分类号： C07K16/24

CPC分类号： C07K16/244 ,  A61K2039/505 ,  C07K2317/21 ,  C07K2317/76 ,  C07K2317/92

摘要： The disclosure relates to an isolated IL-17-binding agent which comprises an immunoglobulin heavy chain polypeptide comprising SEQ ID NO: 1 and optionally an immunoglobulin light chain polypeptide comprising SEQ ID NO: 23, except that one or more specific of residues of SEQ ID NO: 1 and SEQ ID NO: 23 are replaced with a different residue. The disclosure also provides vectors, compositions, and methods of using the IL-17-binding agent to treat an IL-17-mediated disease.

摘要翻译： 本公开涉及分离的IL-17结合剂，其包含包含SEQ ID NO：1的免疫球蛋白重链多肽和任选的包含SEQ ID NO：23的免疫球蛋白轻链多肽，除了SEQ ID NO：23的一个或多个特异性残基 NO：1和SEQ ID NO：23被不同的残基取代。 本公开还提供了使用IL-17结合剂治疗IL-17介导的疾病的载体，组合物和方法。

公开(公告)号：US08475797B2

公开(公告)日：2013-07-02

申请号：US13211092

申请日：2011-08-16

申请人： Alison Witte ,  Denise Williams ,  Josphine M Cardelli ,  David King ,  David Passmore

发明人： Alison Witte ,  Denise Williams ,  Josphine M Cardelli ,  David King ,  David Passmore

IPC分类号： A61K39/395

CPC分类号： C07K16/249 ,  A61K51/1021 ,  A61K2039/505 ,  C07K16/24 ,  C07K2317/21 ,  C07K2317/55 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/74 ,  C07K2317/76

摘要： The present invention provides isolated anti-interferon alpha monoclonal antibodies, particularly human monoclonal antibodies, that inhibit the biological activity of multiple interferon (IFN) alpha subtypes but do not substantially inhibit the biological activity of IFN alpha 21 or the biological activity of either IFN beta or IFN omega. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided. The invention also provides methods for inhibiting the biological activity of IFN alpha using the antibodies of the invention, as well as methods of treating disease or disorders mediated by IFN alpha, such as autoimmune diseases, transplant rejection and graft versus host disease, by administering the antibodies of the invention.

摘要翻译： 本发明提供分离的抗干扰素α单克隆抗体，特别是人单克隆抗体，其抑制多种干扰素（IFN）α亚型的生物学活性，但基本上不抑制IFNα21的生物活性或IFNβ的生物学活性 或IFNγ。 还提供了免疫偶联物，双特异性分子和包含本发明抗体的药物组合物。 本发明还提供了使用本发明的抗体抑制IFNα的生物学活性的方法，以及通过施用本发明的抗体来治疗由IFNα介导的疾病或病症的方法，例如自身免疫疾病，移植排斥反应和移植物抗宿主病 本发明的抗体。

公开(公告)号：US08290147B2

公开(公告)日：2012-10-16

申请号：US12609888

申请日：2009-10-30

申请人： Gerardo Orlando ,  David King ,  Mark Krumpoch

发明人： Gerardo Orlando ,  David King ,  Mark Krumpoch

IPC分类号： H04L9/28

CPC分类号： H04L9/0637 ,  H03M13/09 ,  H04L9/3236 ,  H04L2209/12

摘要： Systems and methods efficiently process digests, hashes or other results by performing multiplicative functions in parallel with each other. In various embodiments, successive processing stages are provided, with each stage performing parallel multiplicative functions and also combining input terms to reduce the total number of terms that remain to be processed. By progressively combining the active terms into a smaller number of terms for subsequent processing, the time needed to process a result can be significantly reduced.

摘要翻译： 系统和方法通过彼此并行执行乘法函数来有效地处理摘要，散列或其他结果。 在各种实施例中，提供了连续的处理阶段，每个阶段执行并行乘法函数，并且还组合输入项以减少待处理的项的总数。 通过将活动术语逐渐组合成较少数量的术语以用于后续处理，可以显着减少处理结果所需的时间。

公开(公告)号：USD655752S1

公开(公告)日：2012-03-13

申请号：US29384871

申请日：2011-02-04

申请人： David King ,  David Harbinson

设计人： David King ,  David Harbinson