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公开(公告)号:US20090092635A1
公开(公告)日:2009-04-09
申请号:US12192257
申请日:2008-08-15
申请人: David Kirkwood Clarke , Farooq Nasar , Rong Xu , Shakuntala Devi Megati , Michael Albin Egan , Amara Gbellu Luckay
发明人: David Kirkwood Clarke , Farooq Nasar , Rong Xu , Shakuntala Devi Megati , Michael Albin Egan , Amara Gbellu Luckay
IPC分类号: A61K39/12 , A61K39/165 , A61P37/04 , A61P31/12
CPC分类号: A61K39/12 , A61K2039/5254 , A61K2039/5256 , A61K2039/545 , C12N2740/16234 , C12N2760/18734 , C12N2760/18743 , C12N2760/20234 , C12N2760/20243 , Y02A50/412 , Y02A50/466
摘要: The present invention is directed to a method for generating an antigen-specific immune response in a subject in general and in particular to administering a priming dose of an immunogenic composition of a recombinant mumps virus (rMuV) that encodes an antigen followed by administering a boosting dose of recombinant vesicular stomatitis virus (rVSV) encoding an antigen.
摘要翻译: 本发明涉及在一般的受试者中产生抗原特异性免疫应答的方法,特别是给予起始剂量的编码抗原的重组腮腺炎病毒(rMuV)的免疫原性组合物,然后施用加强 剂量的编码抗原的重组水泡性口炎病毒(rVSV)。
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公开(公告)号:US20140056938A1
公开(公告)日:2014-02-27
申请号:US13923527
申请日:2013-06-21
申请人: Scott C. Weaver , Farooq Nasar , Rodion V. Gorchakov , Hilda Guzman , Naomi Forrester , Gustavo Palacios , Ian W. Lipkin , Robert B. Tesh
发明人: Scott C. Weaver , Farooq Nasar , Rodion V. Gorchakov , Hilda Guzman , Naomi Forrester , Gustavo Palacios , Ian W. Lipkin , Robert B. Tesh
IPC分类号: C12N15/86
CPC分类号: C12N15/86 , C12N7/00 , C12N2770/36121
摘要: Embodiments are directed compositions related to Eilat virus and uses thereof.
摘要翻译: 实施方案涉及与埃拉特病毒有关的组合物及其用途。
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公开(公告)号:US09422529B2
公开(公告)日:2016-08-23
申请号:US14525820
申请日:2014-10-28
申请人: Farooq Nasar , Jesse Erasmus , Scott C. Weaver
发明人: Farooq Nasar , Jesse Erasmus , Scott C. Weaver
IPC分类号: C12N7/00 , G01N33/569 , A61K39/12
CPC分类号: C12N7/00 , A61K39/12 , C12N2770/36121 , C12N2770/36134 , G01N33/56983 , G01N2333/181 , G01N2469/20
摘要: Embodiments are directed compositions related to Eilat virus and uses thereof. Certain aspects are directed to the detection of non-Eilat entities using a chimeric Eilat alphavirus as a capture agent.
摘要翻译: 实施方案涉及与埃拉特病毒有关的组合物及其用途。 某些方面涉及使用嵌合的埃拉特甲病毒作为捕获剂检测非埃拉特实体。
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公开(公告)号:US20150175975A1
公开(公告)日:2015-06-25
申请号:US14525820
申请日:2014-10-28
申请人: Farooq Nasar , Jesse Erasmus , Scott C. Weaver
发明人: Farooq Nasar , Jesse Erasmus , Scott C. Weaver
IPC分类号: C12N7/00 , G01N33/569 , A61K39/12
CPC分类号: C12N7/00 , A61K39/12 , C12N2770/36121 , C12N2770/36134 , G01N33/56983 , G01N2333/181 , G01N2469/20
摘要: Embodiments are directed compositions related to Eilat virus and uses thereof. Certain aspects are directed to the detection of non-Eilat entities using a chimeric Eilat alphavirus as a capture agent.
摘要翻译: 实施方案涉及与埃拉特病毒有关的组合物及其用途。 某些方面涉及使用嵌合的埃拉特甲病毒作为捕获剂检测非埃拉特实体。
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公开(公告)号:US20140227765A1
公开(公告)日:2014-08-14
申请号:US14086533
申请日:2013-11-21
申请人: Farooq Nasar , Rodion V. Gorchakov , Andrew D. Haddow , Robert B. Tesh , Hilda Guzman , Scott C. Weaver
发明人: Farooq Nasar , Rodion V. Gorchakov , Andrew D. Haddow , Robert B. Tesh , Hilda Guzman , Scott C. Weaver
IPC分类号: C12N15/74
CPC分类号: C12N15/86 , C07K14/005 , C12N2770/00021 , C12N2770/00043
摘要: Certain embodiments are directed to Negevirus and their polynucleotides and polypeptides.
摘要翻译: 某些实施方案涉及神经病毒及其多核苷酸和多肽。
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6.
公开(公告)号:US09388428B2
公开(公告)日:2016-07-12
申请号:US14086533
申请日:2013-11-21
申请人: Farooq Nasar , Rodion V. Gorchakov , Andrew D. Haddow , Robert B. Tesh , Hilda Guzman , Scott C. Weaver
发明人: Farooq Nasar , Rodion V. Gorchakov , Andrew D. Haddow , Robert B. Tesh , Hilda Guzman , Scott C. Weaver
IPC分类号: C12N15/86 , C07K14/005
CPC分类号: C12N15/86 , C07K14/005 , C12N2770/00021 , C12N2770/00043
摘要: Certain embodiments are directed to Negevirus and their polynucleotides and polypeptides.
摘要翻译: 某些实施方案涉及神经病毒及其多核苷酸和多肽。
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