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公开(公告)号：US5145933A
公开(公告)日：1992-09-08
申请号：US665855
申请日：1991-03-07
Applicant: Bernard F. R. Grisoni , David Pocknell
Inventor： Bernard F. R. Grisoni , David Pocknell
CPC classification number: A61L26/0019 , A61L26/008 , A61L27/18 , C08L83/04 , C08G77/12 , C08G77/20 , C08G77/70
Abstract: Non-friable siloxane gels which can be used for gel dressings and in medical prostheses are made from compositions comprising (A) alkenyl-containing polydiorganosiloxanes; (B) hydrosilicon compounds having at least 3 Si-H groups; (C) SiH end-blocked polydiorganosiloxanes and (D) a catalyst. These compositions cure rapidly at room temperature having a ratio (RHAlk) of SiH:Si-Alkenyl of from 3:1 to 20:1, the percentage of silicon-bonded H atoms provided by (C) not being less than 81.36-(3.6.times.RHAlk) and having a value of from 10% to 90%.
Abstract translation: 可用于凝胶敷料和医用假体的非易碎硅氧烷凝胶由包含（A）含链烯基的聚二有机硅氧烷的组合物制成; （B）具有至少3个Si-H基团的氢硅氧烷化合物; （C）SiH封端聚二有机硅氧烷和（D）催化剂。 这些组合物在室温下快速固化，其中SiH:Si-烯基的比率（RHAlk）为3：1至20：1，由（C）提供的硅键合H原子的百分比不低于81.36-（3.6 xRHAlk），其值为10％至90％。
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公开(公告)号：US4991574A
公开(公告)日：1991-02-12
申请号：US568539
申请日：1990-08-15
Applicant: David Pocknell
Inventor： David Pocknell
CPC classification number: A61L15/26 , Y10S128/21
Abstract: A surgical dressing comprising a sheet of silicone gel having a wound-facing surface and laminated to the other surface a film of silicone elastomer.The dressing is particularly adapted to the treatment of burns.
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公开(公告)号：US5348392A
公开(公告)日：1994-09-20
申请号：US133538
申请日：1993-10-07
Applicant: Philippe L. Bouquet , David Pocknell , Werner Bruning , Martina Dittrich-Duster , Gunter Lamers
Inventor： Philippe L. Bouquet , David Pocknell , Werner Bruning , Martina Dittrich-Duster , Gunter Lamers
CPC classification number: C08J9/02 , A61C5/064 , A61C9/0026 , A61L26/0019 , A61L26/0085 , B65D81/325 , C08L83/04 , C08J2383/04
Abstract: The apparatus is adapted to be held in one hand of an operator from mixing components of a composition packaged as two or more individually stable components of substantially equal volume and viscosity each in a receptacle having a closure made of a material which can be ruptured, and to dispense the mixed composition by a manual operation. The device comprises a mixing housing, separate chambers for the receptacles, piercing means for piercing the receptacles, plunger means for expelling a component from the chamber into the mixing region, a mixing element in the mixing region, and a passageway which contains means for actuating the mixing element and through which the mixed composition may be expelled from the mixing region. The construction and arrangement is such that relative movement of approach may be caused between the piercing means and the receptacles to rupture the receptacles, and between the plunger means and the mixing housing to urge the component into the mixing region, the mixing element may be actuated to mix the components in the mixing region, and relative movement of approach may be brought about between elements of the device to discharge the mixed composition through said passageway. The device is principally intended for mixing and dispensing of silicone foam to provide foamed dressings.
Abstract translation: 该装置适于被保持在操作者的一只手中，将组合物的组分混合成两个或多个单独稳定的组分，其基本上相同的体积和粘度各自在具有由可破裂的材料制成的封闭件的容器中;以及 通过手动操作分配混合组合物。 该装置包括混合壳体，用于容器的独立室，用于刺穿容器的刺穿装置，用于将组件从腔室排出到混合区域中的柱塞装置，混合区域中的混合元件，以及包含用于致动 混合组分可以从混合区域排出。 该结构和布置使得在穿孔装置和容器之间可能引起接近的相对运动来破裂容器，并且在柱塞装置和混合壳体之间推动组件进入混合区域，可以致动混合元件 以混合混合区域中的组分，并且可能在装置的元件之间进行相对运动，以通过所述通道排出混合组合物。 该装置主要用于混合和分配硅氧烷泡沫以提供泡沫敷料。
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公开(公告)号：US4719243A
公开(公告)日：1988-01-12
申请号：US928939
申请日：1986-11-10
Applicant: David Pocknell
Inventor： David Pocknell
CPC classification number: C08J9/14 , C08J2383/04 , Y10S528/901
Abstract: The specification is directed to polysiloxane foams. There are disclosed compositions capable of curing at room temperature which comprise a hydroxypolysiloxane, an alkylhydrogen polysiloxane, a tin compound as catalyst and finely divided filler. According to the invention storage stability of these foam forming polysiloxane compositions is improved by use as filler of silica which has been pretreated to render is hydrophobic. The subject compositions may comprise two components which do not require individual mixing prior to mixing together of the components. The compositions may be packaged in any convenient manner. The compositions may be used for a variety of purposes, for example to provide medical dressings.
Abstract translation: 该说明书涉及聚硅氧烷泡沫体。 公开了能够在室温下固化的组合物，其包含羟基聚硅氧烷，烷基氢聚硅氧烷，锡化合物作为催化剂和细分散的填料。 根据本发明，这些泡沫形成聚硅氧烷组合物的储存稳定性通过用作预处理以形成疏水性的二氧化硅填料而得到改善。 主题组合物可以包括两种组分，其在将组分混合在一起之前不需要单独混合。 组合物可以以任何方便的方式包装。 组合物可用于各种目的，例如用于提供医用敷料。
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Patent Agency Ranking
公开(公告)号：US4660553A
公开(公告)日：1987-04-28
申请号：US735246
申请日：1985-06-21
Applicant: Clifford Naylor , David Pocknell
Inventor： Clifford Naylor , David Pocknell
CPC classification number: A61L15/425 , A61L15/26
Abstract: A medical-surgical dressing comprising a reinforced sheet of silicone elastomer foam having a thickness not exceeding 10 millimeters, one of the surfaces of the sheet having a surface layer of open cell foam and the other surface having a substantially non-cellular surface skin. The dressing may be manufactured by a process comprising depositing a liquid foamable silicone composition on an absorbent surface, allowing the composition to foam and set to an elastomer and thereafter separating the foam sheet from the substrate.The dressings are useful e.g. for the treatment of wounds, burns and as liners for plaster casts.
Abstract translation: 一种医用外科敷料，其包括厚度不超过10毫米的硅氧烷弹性体泡沫增强片，片的表面之一具有开孔泡沫的表面层，另一表面具有基本上非细胞表面的皮肤。 敷料可以通过包括在吸收剂表面上沉积液体可发泡聚硅氧烷组合物的方法制造，使组合物发泡并固化成弹性体，然后将泡沫片材与基底分离。 敷料是有用的，例如 用于治疗伤口，烧伤和石膏铸造的衬垫。
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公开(公告)号：US5153231A
公开(公告)日：1992-10-06
申请号：US849855
申请日：1992-03-12
Applicant: Philippe L. Bouquet , David Pocknell
Inventor： Philippe L. Bouquet , David Pocknell
IPC: A61C9/00 , A61L26/00 , B65D81/32 , C08J9/02 , C08K5/06 , C08K5/5419 , C08L83/04 , C08L83/05 , C08L83/06 , C08L83/07
CPC classification number: C08J9/02 , A61C5/064 , A61C9/0026 , A61L26/0019 , A61L26/0085 , B65D81/325 , C08L83/04 , C08J2383/04
Abstract: A multi-component foamable silicone composition is described and claimed which is capable of curing quickly at 20.degree. C. to provide a low density foamed mass. The composition comprises (A) one or more polydiorganosiloxanes having not less than three alkyl-hydrogensiloxane units per molecule, (B) one or more polydiorganosiloxanes having not less than two alkenyl-siloxane units (C) a liquid alcohol, (D) a fluorinated silicone foam stabilizing material and (E) a platinum catalyst for promoting reaction between the components. The composition may be packaged as two or more individually stable parts of substantially equal volume and viscosity each in a receptacle of material which is adapted to be opened by rupture so as to release the components for admixture. The composition is intended for use in forming a foam medical dressing by dispensing onto a surface e.g. an open wound and allowing the composition to cure at room temperature.
Abstract translation: 描述和要求保护的多组分可发泡硅氧烷组合物，其能够在20℃下快速固化以提供低密度发泡团块。 该组合物包含（A）每分子具有不少于三个烷基 - 氢硅氧烷单元的一种或多种聚二有机硅氧烷，（B）一种或多种具有不少于2个烯基 - 硅氧烷单元的聚二有机硅氧烷（C）液体醇，（D）氟化 硅氧烷泡沫稳定材料和（E）促进组分之间的反应的铂催化剂。 组合物可以作为两个或更多个单独稳定的部分包装，每个部分具有基本上相同的体积和粘度，每个在容器的容器中，其适于通过破裂而打开，以便释放用于混合的组分。 该组合物旨在用于通过分配到表面上形成泡沫医疗敷料，例如， 开放的伤口并使组合物在室温下固化。
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公开(公告)号：US4888074A
公开(公告)日：1989-12-19
申请号：US222441
申请日：1988-07-21
Applicant: David Pocknell
Inventor： David Pocknell
IPC: A61K9/00 , A61K31/565 , A61M31/00
CPC classification number: A61K9/0036 , A61K9/0039 , A61M31/002 , Y10T156/1036 , Y10T156/1062
Abstract: The specification describes and claims a method of making therapeutic rings from a curable silicone rubber based composition. The rings are capable of controlled release of the therapeutic agent in the human or animal body. The method includes the steps of:(i) extruding a first composition comprising a therapeutic agent and a first elastomer-forming silicone composition to provide a core;(ii) extruding a second composition comprising a second elastomer-forming silicone composition to provide a sheath enclosing the core;(iii) bringing together end portions of a piece of extruded core and sheath to form a ring,(iv) effecting crosslinking of the extruded core, and(v) effecting crosslinking of the extruded sheath.
Abstract translation: 本说明书描述并要求从可固化的硅橡胶基组合物制备治疗环的方法。 环能够在人或动物体内控制释放治疗剂。 该方法包括以下步骤：（i）挤出包含治疗剂和第一弹性体形成性硅氧烷组合物的第一组合物以提供核心; （ii）挤出包含第二弹性体形成性硅氧烷组合物的第二组合物，以提供包封芯的护套; （iii）将一片挤出的芯和护套的端部组合在一起形成环，（iv）实现挤出的芯的交联，和（v）实现挤出的护套的交联。
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公开(公告)号：US4791149A
公开(公告)日：1988-12-13
申请号：US929252
申请日：1986-11-10
Applicant: David Pocknell
Inventor： David Pocknell
CPC classification number: C08L83/04 , A61F13/04 , A61L26/0019 , A61L26/0061 , C08G77/12 , C08G77/20 , C08G77/70
Abstract: The specification is directed to making noncellular dressings such as gelatinous wound dressings. According to the invention medical and surgical dressings are made by use of packages which may be held in the hand, and which contain the components of two part curable polysiloxane compositions in such a manner that the component may be mixed in predetermined proportions and dispensed therefrom under the influence of propellant gas. The method avoids the need for manual mixing of such compositions during production of dressings.
Abstract translation: 本说明书旨在制造非细胞敷料，如胶状伤口敷料。 根据本发明，医疗和外科敷料通过使用可以保持在手中的包装制成，并且其包含两部分可固化聚硅氧烷组合物的组分，使得组分可以以预定比例混合并从其中分配 推进剂气体的影响。 该方法避免了在制备敷料期间手动混合这些组合物。
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公开(公告)号：US4572814A
公开(公告)日：1986-02-25
申请号：US509496
申请日：1983-06-30
Applicant: Clifford Naylor , David Pocknell
Inventor： Clifford Naylor , David Pocknell
CPC classification number: A61L15/425 , A61L15/26 , Y10S264/05 , Y10S602/90
Abstract: A medical-surgical dressing comprising a reinforced sheet of silicone elastomer foam having a thickness not exceeding 10 millimeters, one of the surfaces of the sheet having a surface layer of open cell foam and the other surface having a substantially non-cellular surface skin. The dressing may be manufactured by a process comprising depositing a liquid foamable silicone composition on an absorbent surface, allowing the composition to foam and set to an elastomer and thereafter separating the foam sheet from the substrate.The dressings are useful e.g. for the treatment of wounds, burns and as liners for plaster casts.
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