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    Ischemia detection systems for paced-patients using beat-type dependent baseline datasets
    1.
    发明授权
    Ischemia detection systems for paced-patients using beat-type dependent baseline datasets 有权
    使用节拍型依赖基线数据集的针对患者的缺血检测系统

    公开(公告)号：US08805498B1

    公开(公告)日：2014-08-12

    申请号：US12624515

    申请日：2009-11-24

    申请人： David R. Fischell ,  Michael Sasha John ,  David Keenan

    发明人： David R. Fischell ,  Michael Sasha John ,  David Keenan

    IPC分类号： A61N1/362

    CPC分类号： A61N1/37247 ,  A61N1/056 ,  A61N1/36592

    摘要： A device for detecting cardiac ischemia is disclosed. The device includes a processor that is configured to distinguish between two different heart beats types such as ventricularly paced beats and supraventricular beats. The processor collects separate reference data for each beat type indicative of the normal values of a cardiac feature associated with these beat types. The processor performs an ischemia test by separately comparing present values of the cardiac feature for each beat type with the reference values for the corresponding beat type.

    摘要翻译： 公开了一种用于检测心脏缺血的装置。 该装置包括处理器，其被配置为区分两种不同的心跳类型，例如心室起搏节拍和室上搏动。 处理器针对指示与这些节拍类型相关联的心脏特征的正常值的每个节拍类型收集单独的参考数据。 处理器通过将每个节拍类型的心脏特征的当前值与相应节拍类型的参考值分开比较来执行缺血测试。

    Ischemia detection systems for paced-patients having three different detection modes
    4.
    发明授权
    Ischemia detection systems for paced-patients having three different detection modes 有权
    具有三种不同检测模式的起搏患者的缺血检测系统

    公开(公告)号：US08452404B1

    公开(公告)日：2013-05-28

    申请号：US12624506

    申请日：2009-11-24

    申请人： David R. Fischell ,  Michael Sasha John ,  David Keenan

    发明人： David R. Fischell ,  Michael Sasha John ,  David Keenan

    IPC分类号： A61N1/00 ,  A61B5/0402

    CPC分类号： A61B5/04525 ,  A61B5/0031 ,  A61B5/0456 ,  A61B5/0468 ,  A61B5/0472 ,  A61B5/1112 ,  A61N1/368

    摘要： A device for detecting cardiac ischemia is disclosed. The device includes a processor that is configured to operate in three different modes according to relative frequency of different beat types. If beats of a first beat type, such as ventricularly paced beats, are predominant, the processor ignores other beat types and performs ischemia detection only on ventricularly paced beats. Conversely, if beats of a second beat type, such as sinus or atrially paced beats, are predominant, the processor ignores ventricularly paced beats and performs ischemia detection only on sinus or atrially paced beats. If there is a mixture of beat types such that neither predominates, the processor performs ischemia detection on both beat types.

    摘要翻译： 公开了一种用于检测心脏缺血的装置。 该装置包括处理器，其配置为根据不同拍子类型的相对频率在三种不同模式下操作。 如果头部节拍类型（例如心室起搏节拍）占优势，则处理器忽略其他节拍类型，仅针对心室起搏节拍进行缺血检测。 相反，如果第二节拍类型的节拍（例如窦性或高发性节拍）是主要的，则处理器忽略心室起搏节拍，并且仅对窦性或心率起搏节拍进行缺血检测。 如果没有优势的节拍类型的混合，则处理器对两种节拍类型执行缺血检测。

    Systems and methods of medical monitoring according to patient state
    5.
    发明申请
    Systems and methods of medical monitoring according to patient state 有权
    根据患者状况进行医疗监测的系统和方法

    公开(公告)号：US20070208263A1

    公开(公告)日：2007-09-06

    申请号：US11710902

    申请日：2007-02-27

    申请人： Michael Sasha John ,  David R. Fischell ,  Bruce Hopenfeld

    发明人： Michael Sasha John ,  David R. Fischell ,  Bruce Hopenfeld

    IPC分类号： A61B5/04

    CPC分类号： A61B5/0452 ,  A61B5/0031 ,  A61B5/024 ,  A61B5/7232 ,  A61B5/7264 ,  G06F19/00

    摘要： A system for the detection of cardiac events occurring in a human patient is provided. At least two electrodes are included in the system for obtaining an electrical signal from a patient's heart. An electrical signal processor is electrically coupled to the electrodes for processing the electrical signal. The systems receives data regarding the patient's state (e.g. asleep, exercising). Patient state information is stored in a patient state array, thereby enabling the system to track the patient's state over time, and to select an appropriate test for detecting a cardiac event based on both past and present data regarding the patient's state.

    摘要翻译： 提供了一种用于检测在人类患者中发生的心脏事件的系统。 系统中包括至少两个电极，以从患者的心脏获得电信号。 电信号处理器电耦合到电极以处理电信号。 系统接收关于患者状态的数据（例如睡眠，锻炼）。 患者状态信息被存储在患者状态阵列中，从而使得系统能够随着时间跟踪患者的状态，并且基于关于患者状态的过去和现在数据来选择用于检测心脏事件的适当测试。

    Adaptive conductive lead systems
    6.
    发明授权
    Adaptive conductive lead systems 失效
    自适应导电导线系统

    公开(公告)号：US08538552B2

    公开(公告)日：2013-09-17

    申请号：US11970781

    申请日：2008-01-08

    申请人： Michael Sasha John ,  David R. Fischell

    发明人： Michael Sasha John ,  David R. Fischell

    IPC分类号： A61N1/00

    CPC分类号： A61N1/05 ,  A61N1/086

    摘要： The invention describes fluid-based lead systems. The fluid-based leads may be used for sensing from, and stimulating of, human tissue. The fluid-based leads can be used to transfer signals between two locations. The fluid-based leads offer advantages when communicating signals along their length since the leads may be safely used in magnetic environments and offer increased elastic characteristics which are less prone to breakage. The leads can be used externally or with implantable devices, such as those used to monitor, and deliver therapy during the treatment of medical disorders such as cardiac and neurological disorders.

    摘要翻译： 本发明描述了基于流体的铅系统。 基于流体的引线可用于感测和刺激人体组织。 基于流体的引线可用于在两个位置之间传输信号。 当基于流体的导线沿着它们的长度传递信号时，提供了优点，因为引线可以安全地用于磁性环境中并提供增加的弹性特性，这些特性不容易断裂。 引线可以在外部使用，也可以使用可植入的装置，例如用于监测的药物，以及治疗诸如心脏和神经障碍等医学疾病期间的治疗。

    Alarm testing and backup for implanted medical devices with vibration alerts
    7.
    发明授权
    Alarm testing and backup for implanted medical devices with vibration alerts 有权
    具有振动警报的植入式医疗设备的报警测试和备份

    公开(公告)号：US08301231B2

    公开(公告)日：2012-10-30

    申请号：US12461877

    申请日：2009-08-27

    申请人： David R. Fischell ,  Jonathan Harwood ,  Michael Sasha John

    发明人： David R. Fischell ,  Jonathan Harwood ,  Michael Sasha John

    IPC分类号： A61B5/04

    CPC分类号： A61B5/0402 ,  A61B5/6846 ,  A61B2560/0271 ,  A61B2560/0276 ,  A61B2562/0219 ,  A61N1/37258 ,  G16H40/67

    摘要： Alarm tests are disclosed which use alarm test signals to assess alarms provided by medical devices. Especially relevant are implanted devices that monitor cardiac activity and provide notification in response to medically relevant events. Alarm tests can occur periodically, or in response to a patient, doctor, or remote party initiating the alarm test. Alarm tests can also occur during the actual alarms issued to detected medical events. Alarm tests lead to pass or fail results, which in turn may cause operations to contingently occur. Alarm test failure in the auditory, visual, or tactile modality, may cause an alternatively defined alarm signal to be used as back-up. Alarm test logs can store alarm test results, including quantification of the measured alarm signal. Rapid alarm tests are described, as are various methods of accurately measuring characteristics of the test signal in ambulatory patients, which are especially relevant to a vibration alarm.

    摘要翻译： 公开了报警测试，其使用报警测试信号来评估由医疗设备提供的警报。 特别相关的是监测心脏活动的植入装置，并响应医疗相关事件提供通知。 报警测试可以周期性地发生，或者响应于启动报警测试的病人，医生或远程方。 在检测到的医疗事件发生的实际警报中也可能发生报警测试。 报警测试导致通过或失败结果，这反过来可能导致操作偶然发生。 在听觉，视觉或触觉模式中的报警测试失败可能导致备用定义的报警信号用作备份。 报警测试记录可以存储报警测试结果，包括测量报警信号的量化。 描述了快速报警测试，以及精确测量门诊患者测试信号特性的各种方法，这些特征与振动报警特别相关。

    System and methods for sliding-scale cardiac event detection
    9.
    发明申请
    System and methods for sliding-scale cardiac event detection 有权
    用于滑动式心脏事件检测的系统和方法

    公开(公告)号：US20080188763A1

    公开(公告)日：2008-08-07

    申请号：US12068776

    申请日：2008-02-12

    申请人： Michael Sasha John ,  David R. Fischell ,  Bruce Hopenfeld

    发明人： Michael Sasha John ,  David R. Fischell ,  Bruce Hopenfeld

    IPC分类号： A61B5/0402

    CPC分类号： A61B5/0452 ,  A61B5/0031 ,  A61B5/024 ,  A61B5/7232

    摘要： A system for the detection of cardiac events occurring in a human patient is provided. At least two electrodes are included in the system for obtaining an electrical signal from a patient's heart. An electrical signal processor is electrically coupled to the electrodes for processing the electrical signal. The system determines the presence of a cardiovascular condition by applying a sliding scale rule to heart signal feature values. When the cardiovascular condition is ischemia, the ST segment may be analyzed. A sliding scale is applied to ST segment shifts such that when the magnitudes of ST segment shifts are relatively small, a larger number of beats is required to detect ischemia compared to the case when the magnitudes of ST shifts are large.

    摘要翻译： 提供了一种用于检测在人类患者中发生的心脏事件的系统。 系统中包括至少两个电极，以从患者的心脏获得电信号。 电信号处理器电耦合到电极以处理电信号。 该系统通过将滑动比例规则应用于心脏信号特征值来确定心血管疾病的存在。 当心血管疾病缺血时，ST段可能被分析。 将滑动刻度应用于ST段移位，使得当ST段移位的幅度相对较小时，与ST移位量大的情况相比，需要较大数量的搏动来检测缺血。

    Systems and methods of medical monitoring according to patient state
    10.
    发明授权
    Systems and methods of medical monitoring according to patient state 有权
    根据患者状况进行医疗监测的系统和方法

    公开(公告)号：US08838215B2

    公开(公告)日：2014-09-16

    申请号：US11710902

    申请日：2007-02-27

    申请人： Michael Sasha John ,  David R. Fischell ,  Bruce Hopenfeld

    发明人： Michael Sasha John ,  David R. Fischell ,  Bruce Hopenfeld

    IPC分类号： A61B5/04 ,  A61B5/0452 ,  A61B5/00 ,  A61B5/024

    CPC分类号： A61B5/0452 ,  A61B5/0031 ,  A61B5/024 ,  A61B5/7232 ,  A61B5/7264 ,  G06F19/00

    摘要： A system for the detection of cardiac events occurring in a human patient. At least two electrodes are included in the system for obtaining an electrical signal from a patient's heart. An electrical signal processor is electrically coupled to the electrodes for processing the electrical signal. The system receives data regarding the patient's state (e.g. asleep, exercising). Patient state information is stored in a patient state array, thereby enabling the system to track the patient's state over time, and to select an appropriate test for detecting a cardiac event based on both past and present data regarding the patient's state.

    摘要翻译： 用于检测在人类患者中发生的心脏事件的系统。 系统中包括至少两个电极，以从患者的心脏获得电信号。 电信号处理器电耦合到电极以处理电信号。 系统接收关于患者状态的数据（例如睡眠，锻炼）。 患者状态信息被存储在患者状态阵列中，从而使得系统能够随着时间跟踪患者的状态，并且基于关于患者状态的过去和现在数据来选择用于检测心脏事件的适当测试。