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    Sensor for transcutaneous measurement of vascular access blood flow
    1.
    发明授权
    Sensor for transcutaneous measurement of vascular access blood flow 失效
    用于经皮测量血管通路血流量的传感器

    公开(公告)号：US06804543B2

    公开(公告)日：2004-10-12

    申请号：US10099974

    申请日：2002-03-19

    申请人： David R. Miller ,  David A. Bell ,  Douglas L. Cox ,  Songbiao Zhang

    发明人： David R. Miller ,  David A. Bell ,  Douglas L. Cox ,  Songbiao Zhang

    IPC分类号： A61B500

    CPC分类号： A61B5/14535 ,  A61B5/0261 ,  A61B5/0275 ,  A61B5/14532 ,  A61B5/14552 ,  A61B5/6843 ,  A61M1/3656 ,  A61M1/3663

    摘要： An optical sensor includes a sensing pair of complementary emitter and detector elements for measuring the bulk absorptivity (&agr;) of an area parallel to and including a hemodialysis access site, and a normalizing pair of complementary emitter and detector elements for measuring the absorptivity (&agr;o) of the tissue itself perpendicular to the access site. The pairs of emitter and detector elements define two lines at right angles to each other, and one of the pairs lies to one side of the line defined by the other of the pairs, such that the two pairs of emitter and detector elements form a “T” shape. Indicator dilution techniques are used to measure vascular access flow rates during routine hemodialysis, using the sensor.

    摘要翻译： 光学传感器包括用于测量平行于并包括血液透析进入位置的区域的体积吸收率（α）的互补发射器和检测器元件的感测对，以及用于测量吸收率（αo）的归一化互补发射器和检测器元件对， 的组织本身垂直于进入位置。 发射器和检测器元件对定义了彼此成直角的两条线，并且其中一对位于由另一对对限定的线的一侧，使得两对发射极和检测器元件形成“ T“形。 使用指示剂稀释技术在常规血液透析期间使用传感器来测量血管通路流速。

    Bladder-based cuff for measuring physiological parameters and method of measuring physiological parameter using same
    2.
    发明申请
    Bladder-based cuff for measuring physiological parameters and method of measuring physiological parameter using same 失效
    用于测量生理参数的膀胱袖带和使用其测量生理参数的方法

    公开(公告)号：US20080132796A1

    公开(公告)日：2008-06-05

    申请号：US11878342

    申请日：2007-07-24

    申请人： Perry N. Law ,  Douglas L. Cox ,  David R. Miller ,  David A. Bell

    发明人： Perry N. Law ,  Douglas L. Cox ,  David R. Miller ,  David A. Bell

    IPC分类号： A61B5/022

    CPC分类号： A61B5/02233 ,  A61B5/02241 ,  A61B5/02422

    摘要： A cuff for measuring volume and change in volume of a body appendage includes a hollow, rigid tube having an inner surface; and a bladder having an inner surface and an outer surface, the ends of the bladder being sealed to the ends of the tube to create an enclosed internal volume between the inner surface of the bladder and the inner surface of the tube and an external volume defined by the outer surface of the bladder and surrounded by the internal volume, the bladder having a normal, relaxed state, in which the internal volume is filled with a fluid and a retracted state in which the fluid is evacuated from the internal volume. Two stiffener ribs placed on the inner surface of the bladder, parallel to each other and to the lengthwise axis of the tube at diametrically opposite positions. A plurality of emitters and detectors arranged in a linear array are embedded in one of the ribs, so as to emit and detect light through the bladder. A fluid port extending through the tube and communicating with the internal volume, through which the internal volume can be filled with or emptied of the fluid.

    摘要翻译： 用于测量身体附件的体积和体积变化的袖带包括具有内表面的中空刚性管; 以及具有内表面和外表面的囊，所述囊的端部被密封到所述管的端部，以在所述囊的内表面和所述管的内表面之间产生封闭的内部容积，并且限定了外部容积 通过膀胱的外表面并被内部体积包围，气囊具有正常的松弛状态，其中内部容积填充有流体和从内部空间排出流体的缩回状态。 两个加强肋布置在囊的内表面上，在直径相对的位置处彼此平行并且与管的纵向轴线平行。 布置成线性阵列的多个发射器和检测器嵌入其中一个肋中，以便通过膀胱发射和检测光。 流体端口延伸穿过管并与内部容积连通，内部容积可以通过该容积填充或排空流体。

    Bladder-based cuff for measuring physiological parameters and method of measuring physiological parameter using same
    3.
    发明授权
    Bladder-based cuff for measuring physiological parameters and method of measuring physiological parameter using same 失效
    用于测量生理参数的膀胱袖带和使用其测量生理参数的方法

    公开(公告)号：US07708694B2

    公开(公告)日：2010-05-04

    申请号：US11878342

    申请日：2007-07-24

    申请人： Perry N. Law ,  Douglas L. Cox ,  David R. Miller ,  David A. Bell

    发明人： Perry N. Law ,  Douglas L. Cox ,  David R. Miller ,  David A. Bell

    IPC分类号： A61B5/00

    CPC分类号： A61B5/02233 ,  A61B5/02241 ,  A61B5/02422

    摘要： A cuff for measuring volume and change in volume of a body appendage includes a hollow, rigid tube having an inner surface; and a bladder having an inner surface and an outer surface, the ends of the bladder being sealed to the ends of the tube to create an enclosed internal volume between the inner surface of the bladder and the inner surface of the tube and an external volume defined by the outer surface of the bladder and surrounded by the internal volume, the bladder having a normal, relaxed state, in which the internal volume is filled with a fluid and a retracted state in which the fluid is evacuated from the internal volume. Two stiffener ribs placed on the inner surface of the bladder, parallel to each other and to the lengthwise axis of the tube at diametrically opposite positions. A plurality of emitters and detectors arranged in a linear array are embedded in one of the ribs, so as to emit and detect light through the bladder. A fluid port extending through the tube and communicating with the internal volume, through which the internal volume can be filled with or emptied of the fluid.

    摘要翻译： 用于测量身体附件的体积和体积变化的袖带包括具有内表面的中空刚性管; 以及具有内表面和外表面的囊，所述囊的端部被密封到所述管的端部，以在所述囊的内表面和所述管的内表面之间产生封闭的内部容积，并且限定外部容积 通过膀胱的外表面并被内部体积包围，气囊具有正常的松弛状态，其中内部容积填充有流体和从内部空间排出流体的缩回状态。 两个加强肋布置在囊的内表面上，在直径相对的位置处彼此平行并且与管的纵向轴线平行。 布置成线性阵列的多个发射器和检测器嵌入其中一个肋中，以便通过膀胱发射和检测光。 流体端口延伸穿过管并与内部容积连通，内部容积可以通过该容积填充或排空流体。

    Bladder-based cuff for measuring physiological parameters and method of measuring physiological parameters using same
    4.
    发明授权
    Bladder-based cuff for measuring physiological parameters and method of measuring physiological parameters using same 有权
    用于测量生理参数的膀胱袖带和使用其测量生理参数的方法

    公开(公告)号：US07247143B2

    公开(公告)日：2007-07-24

    申请号：US10695441

    申请日：2003-10-29

    申请人： Perry N. Law ,  Douglas L. Cox ,  David R. Miller ,  David A. Bell

    发明人： Perry N. Law ,  Douglas L. Cox ,  David R. Miller ,  David A. Bell

    IPC分类号： A61B5/02 ,  A61B17/00

    CPC分类号： A61B5/02233 ,  A61B5/02241 ,  A61B5/02422

    摘要： A cuff for measuring volume and change in volume of a body appendage includes a hollow, rigid tube having an inner surface; and a bladder having an inner surface and an outer surface, the ends of the bladder being sealed to the ends of the tube to create an enclosed internal volume between the inner surface of the bladder and the inner surface of the tube and an external volume defined by the outer surface of the bladder and surrounded by the internal volume, the bladder having a normal, relaxed state, in which the internal volume is filled with a fluid and a retracted state in which the fluid is evacuated from the internal volume. Two stiffener ribs placed on the inner surface of the bladder, parallel to each other and to the lengthwise axis of the tube at diametrically opposite positions. A plurality of emitters and detectors arranged in a linear array are embedded in one of the ribs, so as to emit and detect light through the bladder. A fluid port extending through the tube and communicating with the internal volume, through which the internal volume can be filled with or emptied of the fluid.

    摘要翻译： 用于测量身体附件的体积和体积变化的袖带包括具有内表面的中空刚性管; 以及具有内表面和外表面的囊，所述囊的端部被密封到所述管的端部，以在所述囊的内表面和所述管的内表面之间产生封闭的内部容积，并且限定了外部容积 通过膀胱的外表面并被内部体积包围，气囊具有正常的松弛状态，其中内部容积填充有流体和从内部空间排出流体的缩回状态。 两个加强肋布置在囊的内表面上，在直径相对的位置处彼此平行并且与管的纵向轴线平行。 布置成线性阵列的多个发射器和检测器嵌入其中一个肋中，以便通过膀胱发射和检测光。 流体端口延伸穿过管并与内部容积连通，内部容积可以通过该容积填充或排空流体。

    Method of measuring transcutaneous access blood flow
    6.
    发明授权
    Method of measuring transcutaneous access blood flow 有权
    测量经皮血流量的方法

    公开(公告)号：US06746407B2

    公开(公告)日：2004-06-08

    申请号：US09750122

    申请日：2000-12-29

    申请人： Robert R. Steuer ,  David A. Bell ,  David R. Miller

    发明人： Robert R. Steuer ,  David A. Bell ,  David R. Miller

    IPC分类号： A61B500

    CPC分类号： A61B5/0275 ,  A61M1/3609 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3656

    摘要： Indicator dilution techniques are used to measure vascular access flow rates during routine hemodialysis. A bolus injection port is used to infuse a specific volume (Vi) of an indicator diluent, such as saline or dye, into the patient cardiovascular circuit by one of the following: 1. Needle injection of a known volume (bolus) of indicator diluent directly into the access site in the presence or absence of the hemodialysis circuit. 2. Infusion of an indicator diluent into the arterial, venous line upstream of the venous needle. 3. Turning the ultrafiltration of the dialysis delivery system from OFF to ON and OFF again over a predetermined time period. 4. In a hemodialysis circuit, turning on the hemodialysis pump and using the priming saline volume as a single saline bolus. A transdermal sensor is used to measure the percent change in a blood parameter. The sensor is positioned directly over the vascular access site a prescribed distance downstream of the injection site and upstream of the access-vein connection. The sensor employs emitter and detector elements at multiple spacings (d1, d2) for the purpose of measuring the bulk absorptivity (&agr;) of the area immediately surrounding and including the access site, and the absorptivity (&agr;o) of the tissue itself.

    摘要翻译： 指标稀释技术用于测量常规血液透析期间的血管通路流速。 推注剂注射口用于通过以下之一将特定体积（Vi）的指示剂稀释液（如盐水或染料）注入患者心血管电路：1。 在血液透析电路存在或不存在的情况下，将已知体积（推注）的指示剂稀释液针注射到进入部位。 将指示剂稀释液注入静脉针上游的静脉血管。 在预定时间内将透析递送系统的超滤从OFF切换到ON和OFF。 在血液透析回路中，打开血液透析泵并使用引发盐水体积作为单次生理盐水。用透皮传感器测量血液参数的变化百分比。 传感器直接位于血管通路的上方，位于注射部位下游和进入静脉连接上游的规定距离处。 传感器采用多个间隔（d1，d2）的发射器和检测器元件，用于测量即将包围进入位置的区域的体积吸收率（α），以及组织本身的吸收率（αo）。

    METHODS, SYSTEMS AND APPARATUS TO GENERATE MARKET SEGMENTATION DATA WITH ANONYMOUS LOCATION DATA
    9.
    发明申请
    METHODS, SYSTEMS AND APPARATUS TO GENERATE MARKET SEGMENTATION DATA WITH ANONYMOUS LOCATION DATA 有权
    使用非正常位置数据生成市场分类数据的方法，系统和设备

    公开(公告)号：US20130110634A1

    公开(公告)日：2013-05-02

    申请号：US13721321

    申请日：2012-12-20

    申请人： Laura Cochran ,  David R. Miller ,  Jeff Stevens ,  Mark Nelson

    发明人： Laura Cochran ,  David R. Miller ,  Jeff Stevens ,  Mark Nelson

    IPC分类号： G06Q30/02

    CPC分类号： G06Q30/0267 ,  G06Q30/0201 ,  G06Q30/0204 ,  G06Q30/0261 ,  H04W4/029 ,  H04W4/21

    摘要： Methods and apparatus are disclosed to generate market segmentation data with anonymous location data. A disclosed example method involves receiving geographic location information associated with a mobile phone user, associating the geographic location information with an identifier unrelated to personal information associated with the mobile phone user, identifying a home location associated with the geographic location information, and associating segmentation information with the identifier based on the home location and without referencing personal information of the mobile phone user.

    摘要翻译： 公开了用匿名位置数据产生市场分割数据的方法和装置。 所公开的示例性方法包括接收与移动电话用户相关联的地理位置信息，将地理位置信息与与移动电话用户相关联的个人信息无关的标识符相关联，识别与地理位置信息相关联的归属位置，以及将分段信息 具有基于归属位置的标识符，而不参考移动电话用户的个人信息。