-
公开(公告)号:US08349858B2
公开(公告)日:2013-01-08
申请号:US12663727
申请日:2008-06-18
申请人: Deen Tulshian , William B. Geiss , Gregory S. Martin , Van-Duc Le , James C. Haber, Jr. , Julius J. Matasi , Michael F. Czarniecki , Stephanie Nicole Cooke
发明人: Deen Tulshian , William B. Geiss , Gregory S. Martin , Van-Duc Le , James C. Haber, Jr. , Julius J. Matasi , Michael F. Czarniecki , Stephanie Nicole Cooke
IPC分类号: A01N43/54 , A61K31/505 , C07D239/00 , C07D487/00
CPC分类号: C07D487/14
摘要: The present invention relates to Polycyclic Guanine Derivatives, compositions comprising the Polycyclic Guanine Derivatives and methods of using the Polycyclic Guanine Derivatives to treat pain or an inflammatory disease.
摘要翻译: 本发明涉及多环鸟嘌呤衍生物,包含多环鸟嘌呤衍生物的组合物和使用多环鸟嘌呤衍生物治疗疼痛或炎性疾病的方法。
-
公开(公告)号:US20110065738A1
公开(公告)日:2011-03-17
申请号:US12663727
申请日:2008-06-18
申请人: Deen Tulshian , William B. Geiss , Gregory S. Martin , Van-Duc Le , James C. Haber, JR. , Julius J. Matasi , Michael F. Czarniecki , Stephanie Nicole Cooke
发明人: Deen Tulshian , William B. Geiss , Gregory S. Martin , Van-Duc Le , James C. Haber, JR. , Julius J. Matasi , Michael F. Czarniecki , Stephanie Nicole Cooke
IPC分类号: A61K31/522 , C07D473/18 , A61P29/00 , A61P11/06 , A61P9/00
CPC分类号: C07D487/14
摘要: The present invention relates to Polycyclic Guanine Derivatives, compositions comprising the Polycyclic Guanine Derivatives and methods of using the Polycyclic Guanine Derivatives to treat pain or an inflammatory disease.
摘要翻译: 本发明涉及多环鸟嘌呤衍生物,包含多环鸟嘌呤衍生物的组合物和使用多环鸟嘌呤衍生物治疗疼痛或炎性疾病的方法。
-
公开(公告)号:US5806662A
公开(公告)日:1998-09-15
申请号:US696169
申请日:1996-08-13
申请人: Gregory S. Martin
发明人: Gregory S. Martin
摘要: An endless metal belt (26) for transporting shells (S) through a press (10) which converts the shells into can ends includes a plurality of shell-carrying apertures (32) and a plurality of drive holes (34). The belt is mounted about a pair of spaced-apart cylindrical drums (22,24), at least one of which is rotatably driven. The drive holes are engaged by drive pins (46) extending outwardly from the drive drum (22). Rotation of the drive drum causes the pins to engage the drive holes and advance the belt with the drum. Each drive hole has a hub (58) which is shaped to conform generally to a tapered and contoured edge (48) of a drive pin. At least a portion of the hub protrudes out of the planar surface (56) of the belt, and the pin edge and the lower surface (62) of the hub are mutually shaped to define rolling contact therebetween with no contact between the pin edge and the inner edge (54) of the drive hole.
摘要翻译: 用于通过将壳体转换成罐端部的压力机(10)输送壳体(S)的无端金属带(26)包括多个壳体承载孔(32)和多个驱动孔(34)。 带安装在一对间隔开的圆柱形鼓(22,24)周围,其中至少一个是可旋转地驱动的。 驱动孔通过从驱动滚筒(22)向外延伸的驱动销(46)啮合。 驱动鼓的旋转导致销接合驱动孔并且使带与鼓一起前进。 每个驱动孔具有轮毂(58),轮毂(58)的形状大体上与驱动销的锥形轮廓边缘(48)一致。 轮毂的至少一部分从带的平面表面(56)突出,并且轮毂的销边缘和下表面(62)相互成形,从而在它们之间形成滚动接触,而不会在销边缘和 驱动孔的内边缘(54)。
-
公开(公告)号:US5876171A
公开(公告)日:1999-03-02
申请号:US853421
申请日:1997-05-09
CPC分类号: B21D51/38
摘要: A conversion press (20) which is readily reconfigurable to process shells of different sizes includes an endless belt (68) having a single lane of apertures (86) formed therein for transporting shells (S) along a progression of end-forming tooling (60, 62) comprising seven stations (58a-g) along an end path (59) through the press. A tab-forming tooling path (100) extends from a tab stock feeder (104) to a tab-staking station (58f) adjacent the discharge end of the press, the tab-forming path oriented at an oblique angle to the end path. The tab-forming tools (94, 96) are mounted on tab bases (112, 110) which are slidably adjustable on stationary and reciprocating press members (34, 44) along the tab path toward and away from the tab-staking station. Shells are supplied to the belt by a servo-driven downstacker (120) having feed screws (126) which engage the edge (E) of a shell within a downstacker feed chute (122) and which are adjustably mounted on a downstacker platen (135) to permit their relocation to accommodate changing shell size. Reconfiguring the press to process shells of a different size from about 1 inch to about 4 inches in diameter is accomplished by changing the belt and the end tooling, adjusting the tab tooling bases to accommodate for change in end rivet location, and changing the feed chute and adjusting the downstacker feed screw positions to correspond to the new shell diameter.
摘要翻译: 易于重新配置以处理不同尺寸的壳体的转换压机(20)包括环形带(68),其具有形成在其中的单个通道(86),用于沿着端部成形工具(60)的进展传送壳体 ,62)包括通过压机的沿着端部路径(59)的七个工位(58a-g)。 突片形成工具路径(100)从突片坯料供给器(104)延伸到邻近印刷机排放端的标签桩(58f),片状物形成路径以与倾斜角度倾斜的端部路径相对。 翼片形成工具(94,96)安装在翼片基座(112,110)上,翼片基座(112,110)可沿固定和往复式按压构件(34,44)沿着突片路径可滑动地调节,朝向和远离翼片桩站。 壳体通过伺服驱动的下压器(120)提供给带,该伺服驱动的下压器(120)具有进料螺杆(126),该进料螺杆与嵌入式进料槽(122)内的壳体的边缘(E)接合,并且可调节地安装在下压板 )允许他们搬迁以适应不断变化的壳体尺寸。 重新配置压力机以处理直径约1英寸至约4英寸的不同尺寸的壳体,通过改变带子和端部工具来实现,调节接头工具基座以适应端部铆钉位置的变化,并改变进料槽 并且调节downstacker进料螺杆位置以对应于新的壳直径。
-
-
-