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1.发明授权Long lasting glucagon-like peptide 2 (glp-2) for the treatment of gastrointestinal diseases and disorders 失效持久的胰高血糖素样肽2（glp-2）用于治疗胃肠道疾病和病症公开(公告)号：US07112567B2
公开(公告)日：2006-09-26
申请号：US10203808
申请日：2002-02-15
申请人： Dominique P. Bridon , Nissab Boudjellab , Roger Léger , Martin Robitaille , Karen Thibaudeau , Julie Carette
发明人： Dominique P. Bridon , Nissab Boudjellab , Roger Léger , Martin Robitaille , Karen Thibaudeau , Julie Carette
IPC分类号： A61K38/00
CPC分类号： C07K14/605 , A61K38/26 , A61K38/38 , A61K47/643 , C07K2319/00 , A61K2300/00
摘要： This invention relates to glucagon-like peptide 2 (GLP-2) derivatives. In particular this invention relates to GLP-2 peptide derivatives having an extended in vivo half-life, for the treatment or prevention of gastrointestinal disorders or diseases such as inflammatory bowel disease and other gastrointestinal functions, from any segment of the gastrointestinal tract, from the oesophagus to the anus.
摘要翻译： 本发明涉及胰高血糖素样肽2（GLP-2）衍生物。 特别地，本发明涉及具有延长的体内半衰期的GLP-2肽衍生物，用于治疗或预防来自胃肠道的任何部分的胃肠道疾病或诸如炎性肠病和其它胃肠功能的疾病 食道到肛门。
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2.发明申请LONG LASTING GLUCAGON-LIKE PEPTIDE 2 (GLP-2) FOR THE TREATMENT OF GASTROINTESTINAL DISEASES AND DISORDERS 审中-公开用于治疗胃肠疾病和疾病的长效GLUCAGON-like肽2（GLP-2）公开(公告)号：US20090312259A1
公开(公告)日：2009-12-17
申请号：US12505506
申请日：2009-07-19
申请人： Dominique P. Bridon , Nissab Boudjellab , Roger Leger , Martin Robitaille , Karen Thibaudeau , Julie Carette
发明人： Dominique P. Bridon , Nissab Boudjellab , Roger Leger , Martin Robitaille , Karen Thibaudeau , Julie Carette
IPC分类号： A61K38/16 , C07K14/00 , C07K14/765
CPC分类号： C07K14/605 , A61K38/26 , A61K38/38 , A61K47/643 , C07K2319/00 , A61K2300/00
摘要： This invention relates to glucagon-like peptide 2 (GLP-2) derivatives. In particular, this invention relates to GLP-2 peptide derivatives having an extended in vivo half-life, for the treatment or prevention of gastrointestinal disorders or diseases such as inflammatory bowel disease and other gastrointestinal functions, from any segment of the gastrointestinal tract, from the oesophagus to the anus.
摘要翻译： 本发明涉及胰高血糖素样肽2（GLP-2）衍生物。 特别地，本发明涉及具有延长的体内半衰期的GLP-2肽衍生物，用于治疗或预防胃肠道疾病或疾病如炎性肠病和其他胃肠功能，从胃肠道的任何部分，从 食道到肛门。
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3.发明授权Long lasting glucagon-like peptide 2 (GLP-2) for the treatment of gastrointestinal diseases and disorders 失效持久的胰高血糖素样肽2（GLP-2）用于治疗胃肠道疾病和病症公开(公告)号：US07737251B2
公开(公告)日：2010-06-15
申请号：US11318323
申请日：2005-12-23
申请人： Dominique P. Bridon , Nissab Boudjellab , Roger Leger , Martin Robitaille , Karen Thibaudeau , Julie Carette
发明人： Dominique P. Bridon , Nissab Boudjellab , Roger Leger , Martin Robitaille , Karen Thibaudeau , Julie Carette
CPC分类号： C07K14/605 , A61K38/26 , A61K38/38 , A61K47/643 , C07K2319/00 , A61K2300/00
摘要： This invention relates to glucagon-like peptide 2 (GLP-2) derivatives. In particular, this invention relates to GLP-2 peptide derivatives having an extended in vivo half-life, for the treatment or prevention of gastrointestinal disorders or diseases such as inflammatory bowel disease and other gastrointestinal functions, from any segment of the gastrointestinal tract, from the oesophagus to the anus.
摘要翻译： 本发明涉及胰高血糖素样肽2（GLP-2）衍生物。 特别地，本发明涉及具有延长的体内半衰期的GLP-2肽衍生物，用于治疗或预防胃肠道疾病或疾病如炎性肠病和其它胃肠功能，从胃肠道的任何部分，从 食道到肛门。
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4.发明申请Long lasting glucagon-like peptide 2 (GLP-2) for the treatment of gastrointestinal diseases and disorders 失效持久的胰高血糖素样肽2（GLP-2）用于治疗胃肠道疾病和病症公开(公告)号：US20060217304A1
公开(公告)日：2006-09-28
申请号：US11318323
申请日：2005-12-23
申请人： Dominique Bridon , Nissab Boudjellab , Roger Leger , Martin Robitaille , Karen Thibaudeau , Julie Carette
发明人： Dominique Bridon , Nissab Boudjellab , Roger Leger , Martin Robitaille , Karen Thibaudeau , Julie Carette
IPC分类号： A61K38/26 , C07K14/605
CPC分类号： C07K14/605 , A61K38/26 , A61K38/38 , A61K47/643 , C07K2319/00 , A61K2300/00
摘要： This invention relates to glucagon-like peptide 2 (GLP-2) derivatives. In particular, this invention relates to GLP-2 peptide derivatives having an extended in vivo half-life, for the treatment or prevention of gastrointestinal disorders or diseases such as inflammatory bowel disease and other gastrointestinal functions, from any segment of the gastrointestinal tract, from the oesophagus to the anus.
摘要翻译： 本发明涉及胰高血糖素样肽2（GLP-2）衍生物。 特别地，本发明涉及具有延长的体内半衰期的GLP-2肽衍生物，用于治疗或预防胃肠道疾病或疾病如炎症性肠病和其他胃肠功能，从胃肠道的任何部分，从 食道到肛门。
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公开(公告)号：US20090275506A1
公开(公告)日：2009-11-05
申请号：US12253856
申请日：2008-10-17
申请人： Peter BAKIS , Dominique P. Bridon , Julie Carette , France LeClaire , Roger Leger , Martin Robitaille
发明人： Peter BAKIS , Dominique P. Bridon , Julie Carette , France LeClaire , Roger Leger , Martin Robitaille
CPC分类号： A61K38/2242 , A61K47/62
摘要： This invention relates to long lasting natriuretic peptide (NP) derivatives. The NP derivative has a NP peptide and a reactive entity coupled to the NP peptide. The reactive entity is able to covalently bond with a functionality on a blood component. In particular, this invention relates to NP derivatives having an extended in vivo half-life, and method for the treatment of cardiovascular diseases and disorders such as acute decompensated congestive heart failure (CHF) and chronic CHF.
摘要翻译： 本发明涉及长效利钠肽（NP）衍生物。 NP衍生物具有NP肽和与NP肽偶联的反应性实体。 反应性实体能够与血液成分上的官能团共价键合。 特别地，本发明涉及具有延长的体内半衰期的NP衍生物，以及用于治疗心血管疾病和疾病如急性失代偿性充血性心力衰竭（CHF）和慢性CHF的方法。
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公开(公告)号：US20080199532A1
公开(公告)日：2008-08-21
申请号：US11926843
申请日：2007-10-29
申请人： Peter Bakis , Dominique P. Bridon , Julie Carette , France Leclaire , Roger Leger , Martin Robitaille
发明人： Peter Bakis , Dominique P. Bridon , Julie Carette , France Leclaire , Roger Leger , Martin Robitaille
IPC分类号： A61K35/14 , C07K14/00 , A61K38/16 , A61P11/00 , A61P35/00 , A61P9/00 , C07K14/76 , C07K16/00
CPC分类号： A61K38/2242 , A61K47/62
摘要： This invention relates to long lasting natriuretic peptide (NP) derivatives. The NP derivative has a NP peptide and a reactive entity coupled to the NP peptide. The reactive entity is able to covalently bond with a functionality on a blood component. In particular, this invention relates to NP derivatives having an extended in vivo half-life, and method for the treatment of cardio-vascular diseases and disorders such as acute decompensated congestive heart failure (CHF) and chronic CHF.
摘要翻译： 本发明涉及长效利钠肽（NP）衍生物。 NP衍生物具有NP肽和与NP肽偶联的反应性实体。 反应性实体能够与血液成分上的官能团共价键合。 特别地，本发明涉及具有延长的体内半衰期的NP衍生物，以及用于治疗心血管疾病和疾病如急性失代偿性充血性心力衰竭（CHF）和慢性CHF的方法。
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公开(公告)号：US20050176641A1
公开(公告)日：2005-08-11
申请号：US11040810
申请日：2005-01-21
申请人： Peter Bakis , Dominique Bridon , Julie Carette , France Leclaire , Roger Leger , Martin Robitaille
发明人： Peter Bakis , Dominique Bridon , Julie Carette , France Leclaire , Roger Leger , Martin Robitaille
CPC分类号： A61K38/2242 , A61K47/62
摘要： This invention relates to long lasting natriuretic peptide (NP) derivatives. The NP derivative has a NP peptide and a reactive entity coupled to the NP peptide. The reactive entity is able to covalently bond with a functionality on a blood component. In particular, this invention relates to NP derivatives having an extended in vivo half-life, and method for the treatment of cardiovascular diseases and disorders such as acute decompensated congestive heart failure (CHF) and chronic CHF.
摘要翻译： 本发明涉及长效利钠肽（NP）衍生物。 NP衍生物具有NP肽和与NP肽偶联的反应性实体。 反应性实体能够与血液成分上的官能团共价键合。 特别地，本发明涉及具有延长的体内半衰期的NP衍生物，以及用于治疗心血管疾病和疾病如急性失代偿性充血性心力衰竭（CHF）和慢性CHF的方法。
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