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14 条记录 (耗时 0.033 秒)

    Valve for osmotic devices
    6.
    发明授权
    Valve for osmotic devices 有权

    公开(公告)号：US06508808B1

    公开(公告)日：2003-01-21

    申请号：US09748099

    申请日：2000-12-21

    申请人： John P. Carr ,  James B. Eckenhoff

    发明人： John P. Carr ,  James B. Eckenhoff

    IPC分类号： A61K948

    CPC分类号： A61K9/0004

    摘要： An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule having a beneficial agent reservoir, an osmotic agent which expands on contact with fluid imbibed through a permeable membrane retained by the implant capsule, a delivery port, and a valve for opening and closing the delivery port. When the osmotic agent expands, a pressure is exerted against a separating member positioned between the beneficial agent reservoir and the osmotic agent. The separating member moves within the capsule, thereby forcing the valve to move a distance such that the beneficial agent can exit the reservoir through the delivery port.

    High agent loaded controlled release dispenser
    8.
    发明授权
    High agent loaded controlled release dispenser 失效
    高剂量装载控释装置

    公开(公告)号：US5462741A

    公开(公告)日：1995-10-31

    申请号：US234457

    申请日：1994-04-28

    申请人： John P. Carr ,  Steven D. Larsen ,  James B. Eckenhoff

    发明人： John P. Carr ,  Steven D. Larsen ,  James B. Eckenhoff

    IPC分类号： A61K9/00

    CPC分类号： A61K9/0004

    摘要： A fluid-activated delivery device is disclosed comprising a housing defining an internal compartment, a beneficial agent formulation in the compartment, exit means in the housing for delivering the beneficial agent formulation from the delivery device, and wherein the formulation comprises an active agent in an amount of 50 wt % or greater blended with a glyceride or a mixture of glycerides of a fatty acid.

    摘要翻译： 公开了一种流体激活的输送装置，其包括限定内部隔室的壳体，隔室中的有益剂制剂，壳体中的出口装置，用于将有益剂制剂从输送装置输送，并且其中所述制剂包含活性剂， 与甘油酯或脂肪酸的甘油酯的混合物共混的量为50重量％以上。

    Valve for osmotic devices
    10.
    发明授权
    Valve for osmotic devices 有权
    渗透装置阀

    公开(公告)号：US06682522B2

    公开(公告)日：2004-01-27

    申请号：US10310742

    申请日：2002-12-04

    申请人： John P. Carr ,  James B. Eckenhoff

    发明人： John P. Carr ,  James B. Eckenhoff

    IPC分类号： A61K948

    CPC分类号： A61K9/0004

    摘要： An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule having a beneficial agent reservoir, an osmotic agent which expands on contact with fluid imbibed through a permeable membrane retained by the implant capsule, a delivery port, and a valve for opening and closing the delivery port. When the osmotic agent expands, a pressure is exerted against a separating member positioned between the beneficial agent reservoir and the osmotic agent. The separating member moves within the capsule, thereby forcing the valve to move a distance such that the beneficial agent can exit the reservoir through the delivery port.

    摘要翻译： 用于受控输送有益药剂的渗透递送系统包括具有有益药剂储存器的植入物胶囊，渗透剂，其与通过由植入物胶囊保留的可渗透膜吸收的流体接触而扩张，输送口和用于打开的阀 并关闭送货口。 当渗透剂膨胀时，对位于有益剂储存器和渗透剂之间的分离构件施加压力。 分离构件在胶囊内移动，从而迫使阀移动一定距离，使得有益剂可以通过输送口离开储存器。