摘要:
Novel pyrazolopyridine derivative compounds are disclosed and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors useful in the treatment of cancer and other disease states influenced by TGF beta.
摘要:
The present invention provides kinase inhibitors of Formula I: wherein W represents inter alia imidazol, oxazol, pyrazol, thiazol as triazol, which are substituted by phenyl or thienyl. The disclosed compounds inhibit p-38 kinase and are useful in the treatment of metastasis or rheumatoid arthritis.
摘要:
A system is described for determining how to execute a media campaign (e.g., an advertising campaign) in out-of-home environments (e.g., retail stores or other public places), in such a manner as to enable analysis of the impact of the campaign upon audience behavior, and some of the aspects of audience behavior (recollection of recent exposure, impact of repeat exposures over time) that can be incorporated into subsequent analysis; this can then extend into alterations to the campaign scheduling to optimize business metrics and/or to gain additional, richer information about audience behavior. Media content can be rendered on one or more devices, such as monitors, point of sale systems, and so forth. The media content can include advertisements, such as advertisements having images, video, audio, and multimedia content. Various business constraints and statistical experimental constraints can be satisfied when generating a schedule.
摘要:
A system and method to value media inventory for the display of marketing campaigns on a network of media devices. The system measures past marketing campaign performance and efficiency and assigns a campaign impact value to the advertising opportunity achieved by the execution of past campaigns. Summaries of the campaign impact of past campaigns are stored in a benchmarking archive. The system uses the data contained in the benchmarking archive in order to calculate the value of the network's media inventory, namely the capacity or availability of the network of media devices to play or display future campaigns. The value of the media inventory is used to appropriately assign media inventory to new campaigns that are to be shown on the network of media devices.
摘要:
An apparatus for enhancing the privacy of common privacy enclosures is presented. Two primary embodiments are disclosed. The first embodiment can be used in pre-existing enclosures. The second embodiment is designed where the privacy enhancing screen is incorporated directly into the privacy enclosure's door hinge.
摘要:
The present invention is directed to a compound of formula (I), or a pharmaceutically acceptable salt, solvate, hydrate or stereoisomer thereof, which is useful in treating or preventing disorders mediated by a peroxisome proliferator activated receptor (PPAR), such as syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis, and other disorders related to syndrome X and cardiovascular diseases.
摘要:
A continuous website trial allows ongoing observation of user interactions with website for an indefinite period of time that is not ascertainable at initiation of the trial. Users are randomly assigned to either a control group or one or more test groups. The control and test groups are served different sets of web pages, even though they access the same website. During the trial, the web pages for the control group are held constant over time, while the web pages for the test group(s) undergo multiple modifications at separate occasions over time. As the web pages for the test group(s) are modified, statistical data collection continues to learn how user behavior changes as a result of the modifications. The statistical data obtained from the users of the various groups may be compared and contrasted and used to gain a better understanding of customer experience with the website.
摘要:
A dynamic inventory management system and method for the identification of available inventory on a network of media devices and the optimal scheduling of campaigns, treatments, and content items on the available inventory. To optimize performance of the system, the dynamic inventory management system receives input data from a variety of sources. For example, the dynamic inventory management system receives audience metrics and campaign performance data from analytics systems, event and trigger data from event and trigger systems, and network, content, and campaign metadata from network management systems. The data received from these sources, when used in conjunction with additional rules and parameters that are received from system users, allows the dynamic inventory management system to allocate marketing campaigns, treatments, and content items to available inventory in a manner that is advantageous to both advertisers and to the network operator.
摘要:
A method for spatializing text content for enhanced visual browsing and analysis. The invention is applied to large text document corpora such as digital libraries, regulations and procedures, archived reports, and the like. The text content from these sources may be transformed to a spatial representation that preserves informational characteristics from the documents. The three-dimensional representation may then be visually browsed and analyzed in ways that avoid language processing and that reduce the analysts' effort.
摘要:
Computational and computer-implemented methodological techniques are described for analyzing and presenting data on the audience response to audio and/or visual media advertising campaigns in public places. In various embodiments, these techniques employ a mechanism that assesses audience behavior to produce audience behavior data and audience exposure to produce audience exposure data, a network of display devices that records media events as media event data in a playlog, and a component that assembles the audience behavior data, audience exposure data, and media event data to produce data identifying media events that could have impacted audience behavior and data assessing campaign effectiveness as a measure of audience exposure.