Novel immunocytostaining methods for enhanced dye ratio discrimination in rare event detection
    1.
    发明申请
    Novel immunocytostaining methods for enhanced dye ratio discrimination in rare event detection 有权
    用于在罕见事件检测中增强染料比率鉴别的新型免疫细胞染色方法

    公开(公告)号:US20070166770A1

    公开(公告)日:2007-07-19

    申请号:US11333731

    申请日:2006-01-17

    IPC分类号: G01N33/567

    摘要: A method is provided for preparing a sample containing potential cells of interest and of using a laser of a laser based system for novel excitation and emission collection, and data usage including use of obtained data for direct and ratio based measurements. The prepared sample is configured to emit signals having spectral characteristics sufficient to permit filtering to differentiate and eliminate most false positives from true positives among acquired imaging events, in an imaging system employing a laser spot having a range of diameters from 1 to 20 μm or greater and which excites the fluorescence in a conventional or novel manner. These filtered events may be subsequently imaged and confirmed with another higher resolution device such as a fluorescent microscope in a short amount of time.

    摘要翻译: 提供了一种制备包含潜在感兴趣的细胞的样品并使用基于激光的系统的激光进行新颖的激发和发射采集以及数据使用的方法,包括使用获得的数据进行直接和基于比率的测量。 所制备的样品被配置为发射具有足够的光谱特性的信号,以在使用具有1至20μm或更大直径范围的激光光斑的成像系统中进行滤光以区分并消除所获得的成像事件之间的真阳性的大多数假阳性 并以常规或新颖的方式激发荧光。 这些过滤的事件可以随后在较短的时间内用另一种较高分辨率的装置例如荧光显微镜进行成像和证实。

    Method of scanning and light collection for a rare cell detector
    2.
    发明申请
    Method of scanning and light collection for a rare cell detector 有权
    稀有细胞检测器的扫描和光采集方法

    公开(公告)号:US20060132878A1

    公开(公告)日:2006-06-22

    申请号:US11017440

    申请日:2004-12-20

    IPC分类号: G02B26/08

    摘要: An apparatus images a surface. An imager stage has a planar surface for supporting a sample. A fiber optic bundle has a first end of parallel first fiber ends that are arranged to define an input aperture for viewing the sample on the imager stage. A distal bundle end is arranged to define an output aperture disposed away from the imager stage. A scanning radiation source scans a radiation beam along a path that is perpendicular to the sample on the imager stage. The input aperture of the fiber optic bundle receives a light signal that is produced by the radiation source scan of the imager stage sample. The light signal is transmitted to the bundle output aperture. A photodetector detects the light signal at the distal bundle end, and a processor processes the detected light.

    摘要翻译: 装置对表面进行成像。 成像器台具有用于支撑样品的平坦表面。 光纤束具有平行的第一光纤端的第一端,其布置成限定用于观察成像器台上的样品的输入孔。 远侧束端布置成限定远离成像器台布置的输出孔。 扫描辐射源沿着与成像器台上的样品垂直的路径扫描辐射束。 光纤束的输入孔径接收由成像器台样品的辐射源扫描产生的光信号。 光信号被传输到束输出孔径。 光电检测器检测远侧束端处的光信号,并且处理器处理检测到的光。

    Time-multiplexed scanning light source for multi-probe, multi-laser fluorescence detection systems
    3.
    发明申请
    Time-multiplexed scanning light source for multi-probe, multi-laser fluorescence detection systems 有权
    多探头多激光荧光检测系统的多路复用扫描光源

    公开(公告)号:US20060132778A1

    公开(公告)日:2006-06-22

    申请号:US11018759

    申请日:2004-12-21

    IPC分类号: G01N21/64 G01J3/30

    摘要: An apparatus images a surface. An imager stage linearly translates the surface in a first direction. A light path has a first end defining an input aperture perpendicular to the first direction and parallel to the surface, and a second end defining an output aperture. A plurality of radiation beams linearly scan and interact in time-multiplexed alternating turns with the surface below the input aperture to produce a time-multiplexed light signal that is collected by the input aperture and transmitted by the light path to the output aperture. A photodetector arrangement detects the light signal at the output aperture. A processor processes the detected time-multiplexed light.

    摘要翻译: 装置对表面进行成像。 成像器台沿第一方向线性平移表面。 光路具有限定垂直于第一方向并平行于表面的输入孔的第一端,以及限定输出孔的第二端。 多个辐射束在时间多路复用的交替匝中线性扫描并与输入孔下方的表面相互作用,以产生由输入孔收集并由光路传输到输出孔的时间复用光信号。 光电检测器装置检测输出孔处的光信号。 处理器处理检测到的时间复用光。

    Computational moire compensation
    4.
    发明申请
    Computational moire compensation 失效
    计算莫尔补偿

    公开(公告)号:US20050046904A1

    公开(公告)日:2005-03-03

    申请号:US10646803

    申请日:2003-08-25

    IPC分类号: H04N1/405 G06T5/00 H04N1/409

    CPC分类号: H04N1/4058 H04N1/405

    摘要: The amount of moiré in halftone printed images is reduced using unique moiré intensity functions and moiré vectors in a halftoner. In various embodiments, moiré phase angle zones are determined over the full field of an image and high addressability units in the full-field moiré phase angle zones of the image are adjusted, including in an iterative manner, until they significantly reduce the moiré. A useful relationship between halftoner memory locations and moiré phase angle zones in a full field image is determined. The moiré that occurs in a halftone image is quantified and moiré compensation values obtained are then used to generate an inverse moire amount which is used to compensate for the moiré.

    摘要翻译: 半色调印刷图像中的莫尔数量通过在半色调中使用独特的莫尔强度函数和莫尔矢量来减少。 在各种实施例中,在图像的全场上确定莫尔相位角区域,并且包括以迭代方式调整图像的全场莫尔相位角区域中的高可寻址性单位,直到它们显着减少莫尔条纹。 确定全场图像中的半色调记忆位置和莫尔相位角区域之间的有用关系。 在半色调图像中发生的波纹被量化,然后使用获得的莫尔补偿值来产生用于补偿波纹的反莫尔量。

    Computational moiré compensation
    5.
    发明授权
    Computational moiré compensation 失效
    计算莫尔补偿

    公开(公告)号:US07342696B2

    公开(公告)日:2008-03-11

    申请号:US10646803

    申请日:2003-08-25

    IPC分类号: H04N1/46 G06K9/38

    CPC分类号: H04N1/4058 H04N1/405

    摘要: The amount of moiré in halftone printed images is reduced using unique moiré intensity functions and moiré vectors in a halftoner. In various embodiments, moiré phase angle zones are determined over the full field of an image and high addressability units in the full-field moiré phase angle zones of the image are adjusted, including in an iterative manner, until they significantly reduce the moiré. A useful relationship between halftoner memory locations and moiré phase angle zones in a full field image is determined. The moiré that occurs in a halftone image is quantified and moiré compensation values obtained are then used to generate an inverse moire amount which is used to compensate for the moiré.

    摘要翻译: 半色调印刷图像中的莫尔数量通过在半色调中使用独特的莫尔强度函数和莫尔矢量来减少。 在各种实施例中,在图像的全场上确定莫尔相位角区域,并且包括以迭代方式调整图像的全场莫尔相位角区域中的高可寻址性单位,直到它们显着减少莫尔条纹。 确定全场图像中的半色调记忆位置和莫尔相位角区域之间的有用关系。 在半色调图像中发生的波纹被量化,然后使用获得的莫尔补偿值来产生用于补偿波纹的反莫尔量。

    Solar cell production using non-contact patterning and direct-write metallization
    6.
    发明申请
    Solar cell production using non-contact patterning and direct-write metallization 审中-公开
    使用非接触式图案化和直接写入金属化的太阳能电池生产

    公开(公告)号:US20070169806A1

    公开(公告)日:2007-07-26

    申请号:US11336714

    申请日:2006-01-20

    IPC分类号: H01L31/00

    摘要: Photovoltaic devices (i.e., solar cells) are formed using non-contact patterning apparatus (e.g., a laser-based patterning systems) to define contact openings through a passivation layer, and direct-write metallization apparatus (e.g., an inkjet-type printing or extrusion-type deposition apparatus) to deposit metallization into the contact openings and over the passivation surface. The metallization includes two portions: a contact (e.g., silicide-producing) material is deposited into the contact openings, then a highly conductive metal is deposited on the contact material and between the contact holes. The device wafers are transported between the patterning and metallization apparatus in hard tooled registration using a conveyor mechanism. Optional sensors are utilized to align the patterning and metallization apparatus to the contact openings. An extrusion-type apparatus is used to form grid lines having a high aspect central metal line that is supported on each side by a transparent material.

    摘要翻译: 使用非接触式图案形成装置(例如,基于激光的图案形成系统)来形成光电装置(即,太阳能电池),以限定通过钝化层的接触开口,以及直接写入金属化装置(例如喷墨型印刷或 挤出型沉积设备)以将金属化沉积到接触开口中并在钝化表面上。 金属化包括两部分:将接触(例如,产生硅化物)的材料沉积到接触开口中,然后在接触材料上和接触孔之间沉积高导电性金属。 使用传送机构在硬模具配准中,在图案化和金属化装置之间输送装置晶片。 使用可选的传感器来将图案化和金属化装置对准接触开口。 使用挤出型装置形成具有高方位中心金属线的网格线,每条边由透明材料支撑。