公开(公告)号：US12006504B2

公开(公告)日：2024-06-11

申请号：US17669945

申请日：2022-02-11

Applicant: DSM IP Assets B.V. ,  DOW AgroSciences LLC

Inventor： Terence A. Walsh ,  Daniel Gachotte ,  Ann Owens Merlo ,  Paul G. Roessler ,  James George Metz ,  Scott Bevan ,  Jerry M. Kuner

IPC: C12N15/82 ,  C12P7/6427 ,  C12N9/10 ,  C12N9/12

CPC classification number: C12N15/8247 ,  C12P7/6427 ,  C12N9/1029 ,  C12N9/1288

Abstract: The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed).

公开(公告)号：US10669554B2

公开(公告)日：2020-06-02

申请号：US15825107

申请日：2017-11-29

Applicant: Dow AgroSciences LLC ,  DSM IP ASSETS B.V.

Inventor： Terence A. Walsh ,  Daniel Gachotte ,  Ann Owens Merlo ,  Paul Gordon Roessler ,  James Metz ,  Scott Bevan ,  Jerry Kuner

IPC: C12N15/82 ,  C12P7/64 ,  C12N9/10 ,  C12N9/12

Abstract: The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed).

公开(公告)号：US20190010510A1

公开(公告)日：2019-01-10

申请号：US16139534

申请日：2018-09-24

Applicant: DSM IP Assets B.V. ,  Dow AgroSciences LLC

Inventor： Terence A WALSH ,  Daniel Gachotte ,  Ann Owens Merlo ,  Paul G. Roessler ,  James Metz ,  Scott Bevan ,  Jerry Kuner

IPC: C12N15/82 ,  C12P7/64 ,  C12N9/10 ,  C12N9/12

Abstract: The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed).

公开(公告)号：US10793612B2

公开(公告)日：2020-10-06

申请号：US14415115

申请日：2013-07-16

Applicant: Dow AgroSciences LLC

Inventor： Donald J. Merlo ,  Ignacio Larrinua ,  Scott Bevan

IPC: C07K14/415 ,  C12N15/63 ,  C12N15/82

Abstract: This disclosure concerns methods for the design of synthetic nucleic acid sequences that encode polypeptide amino acid repeat regions. This disclosure also concerns the use of such sequences to express a polypeptide of interest that comprises amino acid repeat regions, and organisms comprising such sequences.

公开(公告)号：US11168332B2

公开(公告)日：2021-11-09

申请号：US16890740

申请日：2020-06-02

Applicant: Dow AgroSciences LLC ,  DSM IP ASSETS B.V.

Inventor： Terence A. Walsh ,  Daniel Gachotte ,  Ann Owens Merlo ,  Paul Gordon Roessler ,  James Metz ,  Scott Bevan ,  Jerry Kuner

IPC: C12N15/82 ,  C12P7/64 ,  C12N9/10 ,  C12N9/12

Abstract: The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed).

公开(公告)号：US20180310512A9

公开(公告)日：2018-11-01

申请号：US14726285

申请日：2015-05-29

Applicant: Dow AgroSciences LLC ,  DSM IP ASSETS B.V.

Inventor： Terence A. Walsh ,  Daniel Gachotte ,  Ann Owens Merlo ,  Dayakar Reddy Pareddy ,  James Metz ,  Scott Bevan ,  Jerry Kuner

IPC: A01H5/10 ,  A61K31/202 ,  C12N15/82 ,  C12N9/12 ,  C12N9/10 ,  A23L1/20

CPC classification number: C12N15/8247 ,  A01H5/10 ,  A23L11/07 ,  A23V2002/00 ,  A61K31/202 ,  C12N9/1029 ,  C12N9/1288 ,  C12P7/6427 ,  C12P7/6472 ,  C12Y203/01085

Abstract: The invention provides recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms as well as products obtained from such organisms.

公开(公告)号：US20180073036A1

公开(公告)日：2018-03-15

申请号：US15825107

申请日：2017-11-29

Applicant: Dow AgroSciences LLC ,  DSM IP ASSETS B.V.

Inventor： Terence A. Walsh ,  Daniel Gachotte ,  Ann Owens Merlo ,  Dayakar Reddy Pareddy ,  James Metz ,  Scott Bevan ,  Jerry Kuner

IPC: C12N15/82 ,  C12P7/64 ,  C12N9/10 ,  C12N9/12

Abstract: The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed),

公开(公告)号：US11046968B2

公开(公告)日：2021-06-29

申请号：US16006485

申请日：2018-06-12

Applicant: Dow AgroSciences LLC ,  DSM IP Assets B.V.

Inventor： Terence A. Walsh ,  Daniel J. Gachotte ,  Cory M. Larsen ,  Scott Bevan ,  P. Ann Owens-Merlo ,  James G. Metz ,  Ross Zirkle

IPC: C12N15/82 ,  A23D9/00 ,  C12N9/12 ,  A23K20/158 ,  C11B1/00 ,  C11B1/04 ,  C11B1/10 ,  C12N9/10

Abstract: This disclosure concerns recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The disclosure also concerns methods of making and using such organisms as well as products obtained from such organisms.

公开(公告)号：US20180282711A1

公开(公告)日：2018-10-04

申请号：US16006485

申请日：2018-06-12

Applicant: Dow AgroSciences LLC ,  DSM IP Assets B.V.

Inventor： Terence A. Walsh ,  Daniel J. Gachotte ,  Cory M. Larsen ,  Scott Bevan ,  P. Ann Owens-Merlo ,  James G. Metz ,  Ross Zirkle

IPC: C12N9/10 ,  C12N15/82 ,  C12N9/12 ,  C11B1/04 ,  C11B1/00 ,  A23K20/158 ,  A23D9/00 ,  C11B1/10

Abstract: This disclosure concerns recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The disclosure also concerns methods of making and using such organisms as well as products obtained from such organisms.

公开(公告)号：US09994828B2

公开(公告)日：2018-06-12

申请号：US14555326

申请日：2014-11-26

Applicant: Dow AgroSciences LLC ,  DSM IP Assets B.V.

Inventor： Terence A. Walsh ,  Daniel J. Gachotte ,  Cory M. Larsen ,  Scott Bevan ,  P. Ann Owens-Merlo ,  James G. Metz ,  Ross Zirkle

IPC: C12N9/10 ,  C12N15/82 ,  A23D9/00 ,  C11B1/00 ,  C11B1/04 ,  C11B1/10 ,  A23K20/158 ,  C12N9/12

CPC classification number: C12N9/1029 ,  A23D9/00 ,  A23K20/158 ,  C11B1/00 ,  C11B1/04 ,  C11B1/10 ,  C12N9/1288 ,  C12N15/82 ,  C12N15/8247 ,  C12Y203/01085

Abstract: This disclosure concerns recombinant host organisms genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins that allow for and/or improve the production of PUFAs in the host organism. The disclosure also concerns methods of making and using such organisms as well as products obtained from such organisms.