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    Tubular floating electrode dielectric barrier discharge for applications in sterilization and tissue bonding
    7.
    发明授权
    Tubular floating electrode dielectric barrier discharge for applications in sterilization and tissue bonding 有权
    管状浮动电极电介质阻挡放电用于消毒和组织结合

    公开(公告)号：US09339783B2

    公开(公告)日：2016-05-17

    申请号：US14322113

    申请日：2014-07-02

    Applicant: DREXEL UNIVERSITY

    Inventor： Gregory Fridman ,  Alexander Fridman ,  Alexander F. Gutsol ,  Gennady Friedman ,  David Staack

    IPC: H05F3/00 ,  B01J19/08 ,  A61L2/00 ,  A61L2/14 ,  H05H1/24

    CPC classification number: A61L2/14 ,  A61L2/0011 ,  B01J19/087 ,  H05H1/2406 ,  H05H2001/245 ,  H05H2001/2456 ,  H05H2245/122

    Abstract: Disclosed is a device and method for contacting a biological substrate. A non-thermal plasma device delivers a non-thermal plasma discharge using a dielectric conduit, an igniter electrode and a RF electrode. The dielectric conduit fluidicly communicates a gas therethrough and an igniter electrode ionizes at least a portion of the gas. The RF electrode, disposed circumferentially proximate to the exterior of the dielectric conduit, generates non-thermal plasma from the ionized gas. The non-thermal plasma is discharged from the dielectric conduit and contacts a biological substrate. The non-thermal plasma discharge may be suitable for tissue bonding and sterilization applications.

    Abstract translation: 公开了一种用于接触生物底物的装置和方法。 非热等离子体装置使用电介质导管，点火器电极和RF电极来传送非热等离子体放电。 电介质导管使气体通过其流体连通，并且点火器电极使至少一部分气体电离。 沿电介质导管的外部周向设置的RF电极从电离气体产生非热等离子体。 非热等离子体从电介质导管排出并与生物基板接触。 非热等离子体放电可适用于组织粘合和灭菌应用。

    Methods for non-thermal applications of gas plasma to living tissue
    8.
    发明授权
    Methods for non-thermal applications of gas plasma to living tissue 有权
    气体等离子体对生物体组织非热应用的方法

    公开(公告)号：US08725248B2

    公开(公告)日：2014-05-13

    申请号：US13950614

    申请日：2013-07-25

    Applicant: Drexel University

    Inventor： Alexander F. Gutsol ,  Alexander Fridman ,  Gennady Friedman ,  Gregory Fridman

    IPC: A61N1/06

    CPC classification number: A61B18/042 ,  A61N1/40 ,  H05H1/2406 ,  H05H2001/2412 ,  H05H2240/20 ,  H05H2245/122

    Abstract: Method for the non-thermal treatment of human or animal tissue with high-voltage electrical discharge plasma is disclosed. The disclosed method employs current through plasma and through tissue not for the purpose of heating the tissue, but instead to maintain the plasma proximate to the tissue being treated. Also disclosed is a method of limiting the current through plasma and through tissue to minimize tissue heating by placement of an insulator or semiconductor between an electrode and tissue resulting in generation of a high-voltage discharge similar to a dielectric barrier discharge. The disclosed non-thermal plasma treatment can be employed to promote coagulation of blood, sterilization, disinfection, re-connection of tissue, and treatment of tissue disorders without causing significant thermal tissue damage.

    Abstract translation: 公开了用高压放电等离子体对人体或动物组织进行非热处理的方法。 所公开的方法采用电流通过等离子体和通过组织而不是用于加热组织的目的，而是将血浆保持在靠近待治疗组织的位置。 还公开了一种限制通过等离子体和通过组织的电流的方法，以通过在电极和组织之间放置绝缘体或半导体来最小化组织加热，导致产生类似于电介质阻挡放电的高压放电。 所公开的非热等离子体处理可用于促进血液凝结，消毒，消毒，组织再连接，以及治疗组织疾病而不引起明显的热组织损伤。

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