公开(公告)号：US20240238127A1

公开(公告)日：2024-07-18

申请号：US18315950

申请日：2023-05-11

申请人： Darwin Precisions Corporation

发明人： Chi-Ying LU

IPC分类号： A61F13/00 ,  A61N1/04

CPC分类号： A61F13/00034 ,  A61F13/00012 ,  A61F13/00029 ,  A61F13/00991 ,  A61N1/0468

摘要： A wound dressing is provided in some embodiments of the present disclosure. The wound dressing includes a porous substrate and a functional layer disposed on the porous substrate. The functional layer is charged or has conductivity. A method of manufacturing a wound dressing is further provided in some embodiments of the present disclosure.

公开(公告)号：US20240189613A1

公开(公告)日：2024-06-13

申请号：US18486722

申请日：2023-10-13

申请人： Drexel University

发明人： Peter C. Friedman ,  Vandana Miller ,  Gregory Fridman ,  Abraham Lin ,  Alexander Fridman

IPC分类号： A61N1/44 ,  A61N1/04 ,  A61N1/08

CPC分类号： A61N1/44 ,  A61N1/08 ,  A61N1/0468

摘要： A method for treating a wart on skin of a patient includes guiding non-thermal, atmospheric pressure plasma over areas of the tissue having the wart for a length of time effective to give rise to an at least partial amelioration of the wart.

公开(公告)号：US20230270996A1

公开(公告)日：2023-08-31

申请号：US18303991

申请日：2023-04-20

申请人： The Feinstein Institutes for Medical Research

发明人： Jared M. HUSTON ,  Jason R. FRITZ ,  Seema G. AMIN ,  Christopher J. CZURA ,  Kevin J. TRACEY

IPC分类号： A61N1/04 ,  A61N1/36 ,  A61N7/00 ,  A61H23/00

CPC分类号： A61N1/0468 ,  A61N1/36034 ,  A61N7/00 ,  A61H23/00 ,  A61N2007/0017 ,  A61H2201/10

摘要： Disclosed are apparatuses and methods for reducing or limiting bleeding (e.g., blood loss and/or bleeding time) in an animal by trigeminal stimulation. The apparatuses and methods may activate one or more branches of the trigeminal nerve. This activation may be invasive or non-invasive.

公开(公告)号：US20190240475A1

公开(公告)日：2019-08-08

申请号：US16267635

申请日：2019-02-05

申请人： Adlore, Inc.

发明人： Daryl Lawson ,  Christopher Brian Arena

IPC分类号： A61N1/04 ,  A61F7/00 ,  A61N1/36 ,  A61B5/053 ,  A61B5/145 ,  A61B5/01

CPC分类号： A61N1/0468 ,  A61B5/01 ,  A61B5/0531 ,  A61B5/14507 ,  A61B5/14539 ,  A61F7/007 ,  A61F2007/0043 ,  A61F2007/0045 ,  A61F2007/0075 ,  A61N1/0484 ,  A61N1/36031

摘要： Disclosed are methods, devices, and systems for treatment of an abnormal wound healing response. The methods, devices, and systems can be used to treat solid ulcerated tissue, such as diabetic foot ulcers (DFUs), arthritic tissue, muscle soreness, joint pain, varicose veins, obesity, and peripheral artery disease. Additionally, the methods, devices, and systems can promote the healing of xenograft, allograft, autograft, or engineered tissue following reconstruction surgery. The methods, devices, and systems include the ability to determine an optimal set of pulse parameters that are specific to wound healing. In embodiments, the methods, devices, and systems include components for guiding the user on electrode placement based on anatomical or electrical measurements, delivering a custom series of electric pulses, applying heat, and using feedback from physiologic measurements to control the device.

公开(公告)号：US20190192853A1

公开(公告)日：2019-06-27

申请号：US15853991

申请日：2017-12-26

申请人： Med Sapiens Co.,LTD

发明人： Hee soo KIM ,  Seung-won SEO

IPC分类号： A61N1/36 ,  A61N1/04 ,  A61N1/08

CPC分类号： A61N1/36034 ,  A61N1/0468 ,  A61N1/0484 ,  A61N1/08 ,  A61N1/36021 ,  A61N1/36071 ,  A61N1/36125

摘要： Disclosed herein is a drive device of an electrode channel for strengthening core muscles of an abdominal region, which can improve circulation of body fluid in a body cavity of the abdominal region and activate muscle membrane tissues inside/outside the abdominal cavity. The drive device includes a wearable instrument worn by a user over an abdominal region, a plurality of electrode channels formed by an electrode pair of a positive-terminal strip and a negative-terminal strip provided on the wearable instrument and contacting a body of the user, and a frequency supply unit for generating and selectively applying Russian current having a middle frequency and interference-wave current between the positive-terminal strip and the negative-terminal strip. Control is performed such that Russian current and interference-wave current are selectively applied to a positive-terminal strip of one of the plurality of electrode channels and a negative-terminal strip of another electrode channel.

公开(公告)号：US20180353365A1

公开(公告)日：2018-12-13

申请号：US16107065

申请日：2018-08-21

申请人： TRUSTEES OF BOSTON UNIVERSITY

发明人： Jason D. Harry ,  James J. Collins ,  James B. Niemi ,  Attila A. Priplata ,  Stephen J. Kleshinski

IPC分类号： A61H1/00 ,  A43B3/00 ,  A61N1/32 ,  A61N1/20 ,  A61N1/04 ,  A61H39/00 ,  A61F5/14 ,  A61F5/01 ,  A43B19/00 ,  A43B17/00 ,  A43B13/00 ,  A43B7/14 ,  A43B7/00 ,  A61N2/06

CPC分类号： A61H1/00 ,  A43B3/0005 ,  A43B7/00 ,  A43B7/1465 ,  A43B13/00 ,  A43B17/00 ,  A43B19/00 ,  A61F5/0111 ,  A61F5/14 ,  A61H39/002 ,  A61H2205/125 ,  A61N1/0456 ,  A61N1/0468 ,  A61N1/0476 ,  A61N1/0484 ,  A61N1/0492 ,  A61N1/20 ,  A61N1/32 ,  A61N2/06

摘要： A method and wearable system and for enhancing human balance and gait and preventing foot injury through neurological stimulation of the foot and the ankle. Subthreshold stimulation for neurosensory enhancement is provided via electrodes or vibrational actuators, or combination thereof, disposed in or on a wearable a platform, such as an insole, sock shoe, removable shoe insert, or applied without the support of a platform, to the skin surface of an individual. Suprathreshold stimulation for therapeutic purposes, such as improving blood flow, is also provided by the vibrational actuators. The actuators and electrodes are driven by bias signals generated by a bias signal generator that is coupled to a controller. The signal generator under the control of the controller is adapted to generate a non-deterministic random signal, a repetitive pattern or series of patterns. The controller optionally includes a communication port for interfacing with an external computer for purposes of optimizing and programming the controller. The wearable system is powered by a power source.

公开(公告)号：US09968774B1

公开(公告)日：2018-05-15

申请号：US14740956

申请日：2015-06-16

申请人： Bruce Hocking

发明人： Bruce Hocking

IPC分类号： A61N1/04

CPC分类号： A61N1/0468 ,  A61H39/002 ,  A61N1/0456 ,  A61N1/0464 ,  A61N1/205 ,  A61N1/36034

摘要： A method of using of a pair of prior art hand-held device known as the Dolphin Neurostim™ to supply minute, concentrated micro-current impulses to the perimeters of cranial sutures for the purpose of tissue diagnosis (through ohm resistance measurement), promotion pain management (through sympathetic deregulation of the Autonomic Nervous System. The micro-current stimulus (therapy) is delivered through a tiny metallic spring tip (probe) ideally suited for location (detection) of specific treatment points (which have the cellular characteristic of lowered skin resistance). The device concurrently detects, measures, and stimulates therapeutically active treatment points located beside sutures. Once detected, the device is activated to deliver a concentrated (DC) micro-current stimulus through the suture tissue to another identical device located (mirrored) on the opposing side of the suture. This unique stimulation when applied as described in this invention re-balances the autonomic and central nervous systems.

公开(公告)号：US20170339776A1

公开(公告)日：2017-11-23

申请号：US15524344

申请日：2015-11-02

申请人： Fourth State Medicine Ltd.

发明人： AARON KNOLL ,  THOMAS HARLE ,  PETER SHAW ,  THOMAS FRAME ,  TOM WANTOCK

IPC分类号： H05H1/34 ,  A61L2/00 ,  A61L2/14 ,  A61N1/04 ,  A61N1/44 ,  A61B18/04 ,  H05H1/24 ,  A61L2/26 ,  A61N1/32 ,  A61B18/00

CPC分类号： H05H1/34 ,  A61B18/042 ,  A61B2018/00452 ,  A61B2018/00476 ,  A61B2018/00577 ,  A61B2018/00595 ,  A61L2/0011 ,  A61L2/14 ,  A61L2/26 ,  A61L2202/11 ,  A61L2202/21 ,  A61L2202/24 ,  A61N1/0424 ,  A61N1/0468 ,  A61N1/328 ,  A61N1/44 ,  H05H1/2406 ,  H05H1/48 ,  H05H2001/3484

摘要： A plasma torch having an open end from which a plasma plume is emitted in use is disclosed. The plasma torch includes a central cathode rod, a grounded conductive tube having an open end and being arranged around the cathode and spaced therefrom to form a first cylindrical cavity open at one end; and a high voltage electrode having a dielectric barrier material at a radially inward-facing surface thereof and being arranged around the grounded conductive tube and spaced apart therefrom to form a second annular cylindrical cavity open at one end. A constant direct current (DC) electrical power plus a high voltage pulsed electrical power is provided to the cathode producing an arc discharge in the first cavity between the cathode and grounded tube to generate a central thermal plasma emitted at an open end of the first cylindrical cavity. A high voltage alternating current electrical power or pulsed electrical power is provided to the high voltage electrode producing a dielectric barrier discharge in the second annular cylindrical cavity to generate a non-thermal plasma emitted from an open end of the second cavity as a halo around the central thermal plasma.

公开(公告)号：US20170296836A1

公开(公告)日：2017-10-19

申请号：US15333862

申请日：2016-10-25

申请人： Danil V. Dobrynin ,  Alexander Fridman ,  Young I. Cho ,  Gregory Fridman ,  Gennady Friedman

发明人： Danil V. Dobrynin ,  Alexander Fridman ,  Young I. Cho ,  Gregory Fridman ,  Gennady Friedman

IPC分类号： A61N1/44 ,  A61N1/04

CPC分类号： A61N1/44 ,  A61N1/0468 ,  A61N1/0472

摘要： Disclosed herein are atmospheric pressure pin-to-hole pulsed spark discharge devices and methods for creating plasma. The devices include a conduit for fluidically communicating a gas, a plasma, or both, therethrough, portion of the conduit capable of being connected to a gas supply, and a second portion of the conduit capable of emitting a plasma; a positive electrode comprising a sharp tip; and a ground plate electrode. Disclosed are methods for treating a skin ulcer using non-thermal plasma include flowing a gas through a cold spark discharge zone simultaneously with the creation of a pulsed spark discharge to give rise to a non-thermal plasma emitted from a conduit, the non-thermal plasma comprising NO; and contacting a skin ulcer with said non-thermal plasma for sufficient time and intensity to give rise to treatment of the skin ulcer.

公开(公告)号：US20170189705A1

公开(公告)日：2017-07-06

申请号：US15307615

申请日：2015-04-10

申请人： Moxi FANG

发明人： Moxi FANG

IPC分类号： A61N1/44 ,  A61N1/04

CPC分类号： A61N1/44 ,  A61L2/02 ,  A61N1/0468 ,  A61N1/0476

摘要： Disclosed are a DNA oxidative damage repairing device and an application method thereof. The device is composed of an electrons emitting assembly, an electrons emitting electrode, a control system, a power source, a support and the like. The device emits electrons to a space in a certain range, negatively charged nano particles with certain density are formed in the space, the space is sterilized, and various hazardous substances in suspension space are eliminated. The negatively charged nano particles entering a body through a respiratory system release electrons carried by the particles, electrons lost due to oxidative damage are replenished to all parts of the body, and dormant state genes can also be repaired and activated. The two-way regulations function can play a role in broad spectrum medical treatment, so that diseases that cannot be cured through drugs easily are present are cured. The device has an obvious curative effect on diseases caused by immune function deficiencies, diseases of a respiratory system, various wounds, diseases caused by drug addiction treatment and the like. The method is combined with correct and effective using of suppressing drugs and accurate using of traditional Chinese medicine, and accordingly a novel hopeful therapeutic scheme of treating AIDS, cancers and various genetic diseases before histone codes are deciphered can be provided.