公开(公告)号：US20240197640A1

公开(公告)日：2024-06-20

申请号：US18474697

申请日：2023-09-26

Applicant: Duke University

Inventor： Conrad P. Hodgkinson ,  Hualing Sun ,  Victor J. Dzau

IPC: A61K9/50 ,  A61P9/00 ,  C12N5/071 ,  C12N15/113

CPC classification number: A61K9/5068 ,  A61P9/00 ,  C12N5/069 ,  C12N15/113 ,  C12N2310/141

Abstract: The present disclosure describes, in part, exosomes comprising miRNA for the reprogramming of fibroblasts and methods of using the same.

公开(公告)号：US20230313160A1

公开(公告)日：2023-10-05

申请号：US18054745

申请日：2022-11-11

Applicant: Duke University

Inventor： Conrad P. Hodgkinson ,  Hualing Sun ,  Richard Pratt ,  Victor J. Dzau

IPC: C12N9/22 ,  C12N15/86 ,  A61P9/12

CPC classification number: C12N9/22 ,  A61P9/12 ,  C12N15/86 ,  C12N2310/20 ,  C12N2750/14143

Abstract: The present disclosure describes compositions and methods for treating hypertension in a subject.