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    Medical device delivery system
    4.
    发明授权
    Medical device delivery system 有权
    医疗器械输送系统

    公开(公告)号：US07871430B2

    公开(公告)日：2011-01-18

    申请号：US10307141

    申请日：2002-11-27

    申请人： Dusan Pavcnik ,  Christopher G. Dixon ,  Jacob A. Flagle ,  Mike Garrison ,  Andrew K. Hoffa ,  Ray Leonard, II ,  Brian C. Case

    发明人： Dusan Pavcnik ,  Christopher G. Dixon ,  Jacob A. Flagle ,  Mike Garrison ,  Andrew K. Hoffa ,  Ray Leonard, II ,  Brian C. Case

    IPC分类号： A61F2/06

    CPC分类号： A61F2/2436 ,  A61F2/95 ,  A61F2002/011 ,  A61F2002/9517

    摘要： A delivery system (10) for implanting a medical device (30) such as a venous valve into the vasculature of a patient. The delivery system includes a delivery catheter (11) having a device-containing portion (15) adjacent to the distal end (14) thereof, and an inner member (16) extending through the catheter and beyond the distal end thereof, to an atraumatic distal tip portion (17) forward of the catheter distal end. The inner member extends through the medical device in the device-containing region, includes a proximal portion (18) with a sufficiently large diameter to prevent longitudinal movement of the device as the catheter is retracted during deployment, and centers the device upon release from the distal catheter end during deployment.

    摘要翻译： 一种用于将诸如静脉瓣的医疗装置（30）植入患者脉管系统的输送系统（10）。 递送系统包括具有与其远端（14）相邻的装置容纳部分（15）的输送导管（11）和延伸穿过导管并超出其远端的内部构件（16）到无创伤 远端尖端部分（17）在导管远端的前方。 内部构件在包含装置的区域中延伸通过医疗装置，包括具有足够大的直径的近端部分（18），以防止在展开期间导管缩回时装置的纵向移动， 远端导管末端部署期间。

    Artificial valve prosthesis with improved flow dynamics
    7.
    发明授权
    Artificial valve prosthesis with improved flow dynamics 有权
    具有改善流动动力学的人造瓣膜假体

    公开(公告)号：US07618447B2

    公开(公告)日：2009-11-17

    申请号：US10828716

    申请日：2004-08-30

    申请人： Brian C. Case ,  Jacob A. Flagle ,  Andrew K. Hoffa ,  Darin G. Schaeffer ,  Michael L. Garrison

    发明人： Brian C. Case ,  Jacob A. Flagle ,  Andrew K. Hoffa ,  Darin G. Schaeffer ,  Michael L. Garrison

    IPC分类号： A61F2/06 ,  A61F2/24

    CPC分类号： A61F2/2418 ,  A61F2/2475 ,  A61F2002/068 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2230/0054 ,  A61F2230/0076 ,  A61F2230/0078 ,  A61F2230/008 ,  A61F2250/0037 ,  A61F2250/0039

    摘要： An expandable venous valve having a support structure that configured to enlarge the area adjacent to the valve structure such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure. In another group of embodiments, the attachment pathway between opposing leaflets and the support frame and/or vessel wall comprises a proximal portion that places the leaflets in extended contact with one another and a distal portion forms a large angle with respect to the adjacent walls such that a large pocket is created at the base of the leaflets. In one embodiment, the attachment pathway extends distally along a pair of substantially parallel longitudinal attachment struts to create an extended leaflet contact area, then angles circumferentially and distally from the former along distal attachment struts to define the bottom edge of the leaflets.

    摘要翻译： 一种可膨胀静脉瓣，其具有支撑结构，该支撑结构被配置为扩大邻近阀结构的区域，使逆行流的流动模式以便于冲洗瓣膜区域底部的口袋的方式进行改变，以防止滞留 在静脉系统中的体液可导致血栓形成。 扩大的口袋区域可以通过在两个支撑框架部分之间的容器壁的无支撑部分中形成邻近阀结构的人造窦来形成，或者支撑框架可以包括形成邻近瓣膜的人造窦的扩张直径的中间或近端部分 结构体。 在另一组实施例中，相对的小叶与支撑框架和/或血管壁之间的附接通路包括将小叶彼此延伸接触的近端部分，并且远侧部分相对于相邻壁形成大角度， 在传单的底部创造了一个大口袋。 在一个实施例中，附接通道沿着一对基本上平行的纵向连接支柱向远侧延伸，以产生延伸的小叶接触区域，然后沿着远侧连接支柱沿着周向和远端远离成形器，以限定传单的底部边缘。

    Delivery systems and methods for deploying expandable intraluminal medical devices
    8.
    发明授权
    Delivery systems and methods for deploying expandable intraluminal medical devices 有权
    用于部署扩张型管腔内医疗器械的输送系统和方法

    公开(公告)号：US07909862B2

    公开(公告)日：2011-03-22

    申请号：US10804386

    申请日：2004-03-19

    申请人： Michael L. Garrison ,  Brian C. Case ,  Andrew K. Hoffa ,  Jacob A. Flagle ,  Dusan Pavcnik

    发明人： Michael L. Garrison ,  Brian C. Case ,  Andrew K. Hoffa ,  Jacob A. Flagle ,  Dusan Pavcnik

    IPC分类号： A61F2/06 ,  A61M29/00

    CPC分类号： A61F2/95 ,  A61F2/013 ,  A61F2/966 ,  A61F2002/011 ,  A61F2002/015 ,  A61F2230/0006 ,  A61F2230/005

    摘要： Methods and devices for delivering and deploying expandable intraluminal medical devices at a desired point of treatment within a body vessel are provided. A delivery device is provided, inserted into a body vessel, and navigated through the vessel to place an associated expandable intraluminal medical device at a desired point of treatment. Once the desired location is reached, an elongate member on which the expandable intraluminal medical device is disposed is spaced from a wall surface of the body vessel using an expandable wire basket, balloon, or other suitable structure. The expandable intraluminal medical device is deployed from the delivery system, which can ultimately be withdrawn from the body vessel.

    摘要翻译： 提供了用于在体内容器内的期望治疗点递送和部署可膨胀管腔内医疗装置的方法和装置。 提供输送装置，插入体内容器，并通过血管导航，将相关的可扩张的管腔内医疗装置放置在期望的治疗点。 一旦达到所需的位置，可扩张的管腔内医疗装置就位于其上的细长构件就可以使用可膨胀的丝网筐，球囊或其它合适的结构与身体容器的壁表面间隔开。 可扩展的管腔内医疗装置从输送系统部署，其最终可以从体内容器中取出。

    Implantable medical device with constrained expansion
    10.
    发明授权
    Implantable medical device with constrained expansion 有权
    植入式医疗器械具有约束扩张

    公开(公告)号：US07128759B2

    公开(公告)日：2006-10-31

    申请号：US10849639

    申请日：2004-05-19

    申请人： Thomas A. Osborne ,  Brian C. Case ,  Jacob A. Flagle ,  Andrew K. Hoffa ,  Michael L. Garrison

    发明人： Thomas A. Osborne ,  Brian C. Case ,  Jacob A. Flagle ,  Andrew K. Hoffa ,  Michael L. Garrison

    IPC分类号： A61F2/06

    CPC分类号： A61F2/2418 ,  A61F2/2475 ,  A61F2220/0008 ,  A61F2220/0016 ,  A61F2220/0075 ,  A61F2230/0026 ,  A61F2230/0095

    摘要： Medical devices for implantation in a body vessel are provided. A medical device according to the invention comprises a support structure and one or more graft members comprising a valve portion and a constraining portion. The support structure has a first, unexpanded configuration and a second, expanded configuration. The constraining portion is adapted to substantially prevent the support structure from achieving the second, expanded configuration. The valve portion is adapted to permit fluid flow through a body vessel in a first direction and substantially prevent fluid flow through the vessel in a second, opposite direction.

    摘要翻译： 提供用于植入体内的医疗装置。 根据本发明的医疗装置包括支撑结构和包括阀部分和约束部分的一个或多个移植部件。 支撑结构具有第一，未膨胀的构造和第二扩展构型。 约束部分适于基本上防止支撑结构实现第二扩张构型。 阀部分适于允许流体沿第一方向流过身体容器，并且基本上防止流体沿第二相反方向流过血管。