公开(公告)号：US20240156358A1

公开(公告)日：2024-05-16

申请号：US18495691

申请日：2023-10-26

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Paul B. Benni ,  Antonio Albanese ,  Anusha Alathur Rangarajan ,  Andres S. Aguirre ,  Brennan Michael Schneider

IPC: A61B5/0205 ,  A61B5/00 ,  A61B5/021 ,  A61B5/026

CPC classification number: A61B5/0205 ,  A61B5/0075 ,  A61B5/026 ,  A61B5/7246 ,  A61B5/021

Abstract: A method for providing autoregulation function information is provided. The method includes: a) continuously sensing a tissue region with a tissue oximeter during a period of time, the sensing producing first signals representative of at least one tissue oxygenation parameter; b) continuously measuring a blood pressure level during the period of time using a blood pressure sensing device, the measuring producing second signals representative of the blood pressure level of the subject; c) evaluating the at least one tissue oxygenation parameter using the first signals and the blood pressure level using the second signals, relative to one another; d) producing a recent profile of autoregulation data using the first and second signals from a recent portion of the period of time; e) producing a historical profile of autoregulation data using the first and second signals from a historical portion of the period of time.

公开(公告)号：US20240081721A1

公开(公告)日：2024-03-14

申请号：US18513075

申请日：2023-11-17

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Paul B. Benni ,  Zhongping Jian ,  Antonio Albanese ,  Andres S. Aguirre ,  Brennan Michael Schneider ,  Anusha Alathur Rangarajan

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/145 ,  A61B5/1455

CPC classification number: A61B5/4064 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/14546 ,  A61B5/14552 ,  A61B5/14553 ,  A61B5/7239 ,  A61B5/725 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/742 ,  A61B5/021

Abstract: A method and apparatus for determining a subject's autoregulation function state is provided. The method includes: continuously sensing a tissue region of a subject with a tissue oximeter to produce first signals representative of at least one tissue oxygenation parameter during a period of time; continuously measuring a blood pressure level of the subject during the period of time to produce second signals representative of the subject's blood pressure during the period of time; determining a presence of a confounding factor that affects the sensed tissue oxygenation parameter in a manner independent of an autoregulation function of the subject, the determination using the first signals; using the first and second signals to determine an autoregulation function state of the subject when the absence of the confounding factor is determined. The method may include determining an at least one of an LLA or a ULA of a subject's autoregulation function state.

公开(公告)号：US20220400965A1

公开(公告)日：2022-12-22

申请号：US17821886

申请日：2022-08-24

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Brennan Michael Schneider ,  Zhongping Jian ,  Feras Al Hatib ,  Sai Prasad Buddi

IPC: A61B5/021 ,  A61B5/00

Abstract: A hemodynamic monitoring system monitors arterial blood pressure of a patient and provides a warning to medical personnel of a predicted future hypotension event of the patient. Waveform analysis is performed on sensed hemodynamic data representative of an arterial pressure waveform of the patient to determine a plurality of hypotension profiling parameters predictive of a future hypotension event for the patient. A set of transformed hypotension profiling parameters is generated based on the hypotension profiling parameters and mean and standard deviation values of the hypotension profiling parameters at a standard mean arterial pressure (MAP) threshold for hypotension and an adjusted MAP threshold for hypotension. A risk score representing a probability of a future hypotension event for the patient is determined based on the set of transformed hypotension profiling parameters. A sensory alarm is invoked to produce a sensory signal in response to the risk score satisfying a predetermined risk criterion.

公开(公告)号：US20220395236A1

公开(公告)日：2022-12-15

申请号：US17821902

申请日：2022-08-24

Applicant: Edwards Lifesciences Corporation

Inventor： Sai Prasad Buddi ,  Brennan Michael Schneider ,  Zhongping Jian ,  Feras Al Hatib

IPC: A61B5/00 ,  A61B5/0215

Abstract: A hemodynamic monitoring system monitors arterial blood pressure of a patient and provides a warning to medical personnel of a predicted future hypotension event of the patient. Sensed hemodynamic data representative of an arterial pressure waveform of the patient are received by a hemodynamic monitor. The received hemodynamic data is offset, based on a difference between a standard mean arterial pressure (MAP) threshold for hypotension and an adjusted MAP threshold for hypotension, to produce adjusted hemodynamic data. Waveform analysis of the adjusted hemodynamic data is performed, and a risk score representing a probability of a future hypotension event for the patient is determined based on the waveform analysis. A sensory alarm is invoked to produce a sensory signal in response to the risk score satisfying a predetermined risk criterion.