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10 条记录 (耗时 0.009 秒)

    Certain pyridyl formamidine derivatives
    4.
    发明授权
    Certain pyridyl formamidine derivatives 失效
    某些吡啶衍生物衍生物

    公开(公告)号：US3557128A

    公开(公告)日：1971-01-19

    申请号：US3557128D

    申请日：1968-03-04

    申请人： EGYT GYOGYSZERVEGYESZETI GYAR

    发明人： PALLOS LASZLO ,  BENKO PAL

    IPC分类号： C07D213/74 ,  C07D31/46

    CPC分类号： C07D213/74

    摘要： THE N-ASRYL OR N-PYRIDYL N'',N''-MONO OR DISUBSTITUTED FORMAMIDINES OF THIS INVENTION ARE PREPARED BY REACTING THE APPROPRIATE N-ARYL OR N-PYRIDYL FORMANIDINE IN THE PRESENCE OF AN ALKYL HALIDE. THE N-ARYL OR N-PRIDY-N'', N''-SUBSTITUTED FORMAMIDINES PRODUCED BY THIS PROCESS HAVE ANTHELMINTIC, ASCARACIDAL AND HERBICIDAL PROPERTIES.

    New formamidine derivatives and process for the preparation thereof
    5.
    发明授权
    New formamidine derivatives and process for the preparation thereof 失效
    新型马来酸衍生物及其制备方法

    公开(公告)号：US3621061A

    公开(公告)日：1971-11-16

    申请号：US3621061D

    申请日：1969-04-11

    申请人： EGYT GYOGYSZERVEGYESZETI GYAR

    发明人： BENKO PAL ,  BUDAI ZOLTAN ,  PALLOS LASZLO

    IPC分类号： C07D213/74

    CPC分类号： C07D213/74

    摘要： Compounds of the general formula I and their acid addition salts

    WHEREIN R stands for a member selected from the group consisting of unsubstituted phenyl, substituted phenyl, and naphthyl radicals, wherein the substituent of the phenyl group is selected from the group consisting of halogen, lower alkyl, lower alkoxy, trihalomethyl, nitro group, and a combination thereof, wherein the halogen substituent may be one or two halogen atoms. These compounds have antimicrobial effect.

    Indazole-3-carboxylic amides
    8.
    发明授权
    Indazole-3-carboxylic amides 失效
    吲哚-3-羧酰胺

    公开(公告)号：US3705175A

    公开(公告)日：1972-12-05

    申请号：US3705175D

    申请日：1970-03-26

    申请人： EGYT GYOGYSZERVEGYESZETI GYAR

    发明人： MAGDANYI LASZLO ,  GELLERI ANDRAS ,  PALLOS LASZLO ,  ERDELYI LUJZA ,  GOROG PETER

    IPC分类号： C07D231/56 ,  C07D487/14 ,  C07D49/18

    CPC分类号： C07D231/56 ,  C07D487/14 ,  Y10S514/91

    摘要： INDAZOLE-3-CARBOXYLIC AMIDES OF THE GENERAL FORMULA

    1-Q,3-(R1-N(-R2)-CO-),5,6-DI(CH3-O-)-1H-INDAZOLE

    WHEREIN R1 AND R2 REPRESENT INDEPENDENTLY HYDROGEN, STRAIGHT CHAINED OR BRANCHED ALKYL OF UP TO 16 CARBON ATOMS, CYCLOALKYL, NAPHTHYL, PHENYL OR ARALKYL GROUP, WHERE THE PHENYL AND ARALKYL GROUPS MAY BE SUBSTITUTED WITH ONE OR TWO LOWER ALKYL, ALKOXY, TRIFLUOROMETHYL OR HALO SUBSTITUENT, FURTHER R1 AND R2 MAY FORM TOGETHER WITH THE ADJACENT NITROGEN ATOM AND OPTIONALLY WITH A FURTHER NITROGEN ATOM A 5 OR 6 MEMBERED HETEROCYCLIC RADICAL, Q REPRESENTS HYDROGEN, ALKALI METAL OR AN ACYL GROUP OF 1 TO 4 CARBON ATOMS HAVE BEEN PREPARED. THE NEW COMPOUNDS POSSESS VALUABLE PHARMACOLOGICAL ACTIVITIES, FIRST ALL THEY ARE POTENT ANTI-INFLAMMATORY AND ANALGESIC AGENTS.

    3-Amino-as-triazino{8 6,5-c{9 quinoline and its 1-oxide, and a process for the preparation thereof
    9.
    发明授权
    3-Amino-as-triazino{8 6,5-c{9 quinoline and its 1-oxide, and a process for the preparation thereof 失效
    3-氨基 - 三嗪嗪{8 6，5-c {9喹啉及其1-氧化物及其制备方法

    公开(公告)号：US3873542A

    公开(公告)日：1975-03-25

    申请号：US35617573

    申请日：1973-05-01

    申请人： EGYT GYOGYSZERVEGYESZETI GYAR

    发明人： BERENYI NEE POLDERMANN EDIT ,  PALLOS LASZLO ,  PETOCZ LUJZA E ,  GOROG PETER ,  BUDAI ZOLTAN ,  KISZELLY ENIKO ,  BENKO PAL

    IPC分类号： C07D215/18 ,  A61K31/53 ,  A61P29/00 ,  A61P31/04 ,  C07D215/42 ,  C07D471/04 ,  C07D57/34

    CPC分类号： C07D471/04 ,  C07D215/42

    摘要： 3-Amino-as-triazino(6,5-c)quinoline or its 1-oxide can be prepared as follows: 4-chloro-3-nitroquinoline is reacted with guanidine, the formed 4-guanidino-3-nitroquinoline is subjected to ring closure in an alkaline medium, and, if desired, the 1oxide group of the thus-obtained 3-amino-as-triazino(6,5-c)quinoline-1-oxide is split off under reductive conditions, the obtained 3-amino-1,2-dihydro-as-triazino(6,5-c)quinoline is oxidized into 3-amino-as-triazino(6,5-c)quinoline, and, if desired, any compound obtained by the above process is converted into its salt. The compounds of the invention are novel and possess valuable anti-inflammatory and antimicrobial activities.

    摘要翻译： 3-氨基 - 三嗪并[6,5-c]喹啉或其1-氧化物可如下制备：将4-氯-3-硝基喹啉与胍反应，将形成的4-胍基-3-硝基喹啉 在碱性介质中闭环，如果需要，由此得到的3-氨基 - 三嗪[6,5-c] - 喹啉-1-氧化物的1-氧化物在还原条件下分离， 得到的3-氨基-1,2-二氢 - 三嗪并[6,5-c]喹啉被氧化为3-氨基 - 三嗪并[6,5-c]喹啉，如果需要， 将上述方法转化为其盐。