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公开(公告)号：US20170320027A1
公开(公告)日：2017-11-09
申请号：US15658503
申请日：2017-07-25
发明人： Martin Morrissey , Brian Pereira
CPC分类号： B01F15/0085 , B01F7/00241 , B01F13/0827 , B01F15/00487 , B01F2215/0034 , B01F2215/0073 , C12M23/14 , C12M27/02
摘要： A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.
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公开(公告)号：US20150298077A1
公开(公告)日：2015-10-22
申请号：US14440373
申请日：2013-11-05
发明人： Martin Morrissey , Brian Pereira
CPC分类号： B01F7/00241 , B01F7/162 , B01F7/1635 , B01F13/0827 , B01F13/0872 , B01F15/0085
摘要： A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The impeller assembly has a protective hood surrounding at least a portion of the moveable blades or vanes of the impeller assembly and being above at least a portion of the blades or vanes. The hood surrounds the blades or vanes and arcs over the height of the blades or vanes. The hood is shaped in a dome shape or semi-spherical shape that is around and above the impeller blades and acts as a protector for the container surface against the impeller assembly both during shipping and storage as well as when in use, particularly at lower liquid levels.
摘要翻译： 用于流体的一次性容器，例如可变形袋，具有一个或多个入口和一个或多个出口以及容器内的叶轮组件，用于引起包含或添加的一种或多种成分的混合，分散，均化和/或循环 到容器 叶轮组件具有围绕叶轮组件的可移动叶片或叶片的至少一部分并且在叶片或叶片的至少一部分上方的保护罩。 发动机罩围绕叶片或叶片并在叶片或叶片的高度上弧形。 发动机罩形成为圆顶形或半球形，其在叶轮叶片周围和上方，并且在运输和储存期间以及在使用时特别是在较低液体下作为用于容器表面抵靠叶轮组件的保护器 水平。
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公开(公告)号：US20210347156A1
公开(公告)日：2021-11-11
申请号：US17287253
申请日：2019-10-23
发明人： Brian Pereira , John Saragosa , Joseph Muldoon
摘要： A material for biocontainers comprising a film formed of two or more layers forming a body to the film, the film having an interior and exterior side, and a substrate incorporated in the body of the film wherein the substrate is formed of a fibrous material, wherein each of the at least one of the two or more layers comprises an ethylene vinyl acetate resin. A non-constrained pressure test is also disclosed.
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公开(公告)号：US20180229192A1
公开(公告)日：2018-08-16
申请号：US15954779
申请日：2018-04-17
发明人： Martin Morrissey , Brian Pereira
CPC分类号： B01F7/00241 , B01F7/162 , B01F7/1635 , B01F13/0827 , B01F13/0872 , B01F15/0085
摘要： A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The impeller assembly has a protective hood surrounding at least a portion of the moveable blades or vanes of the impeller assembly and being above at least a portion of the blades or vanes. The hood surrounds the blades or vanes and arcs over the height of the blades or vanes. The hood is shaped in a dome shape or semi-spherical shape that is around and above the impeller blades and acts as a protector for the container surface against the impeller assembly both during shipping and storage as well as when in use, particularly at lower liquid levels.
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公开(公告)号：US09975095B2
公开(公告)日：2018-05-22
申请号：US14440373
申请日：2013-11-05
发明人： Martin Morrissey , Brian Pereira
CPC分类号： B01F7/00241 , B01F7/162 , B01F7/1635 , B01F13/0827 , B01F13/0872 , B01F15/0085
摘要： A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The impeller assembly has a protective hood surrounding at least a portion of the moveable blades or vanes of the impeller assembly and being above at least a portion of the blades or vanes. The hood surrounds the blades or vanes and arcs over the height of the blades or vanes. The hood is shaped in a dome shape or semi-spherical shape that is around and above the impeller blades and acts as a protector for the container surface against the impeller assembly both during shipping and storage as well as when in use, particularly at lower liquid levels.
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公开(公告)号：US09993785B2
公开(公告)日：2018-06-12
申请号：US15791869
申请日：2017-10-24
发明人： Martin Morrissey , Brian Pereira
CPC分类号： B01F15/0085 , B01F7/00241 , B01F13/0827 , B01F15/00487 , B01F2215/0034 , B01F2215/0073 , C12M23/14 , C12M27/02
摘要： A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.
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公开(公告)号：US09827541B1
公开(公告)日：2017-11-28
申请号：US15658503
申请日：2017-07-25
发明人： Martin Morrissey , Brian Pereira
CPC分类号： B01F15/0085 , B01F7/00241 , B01F13/0827 , B01F15/00487 , B01F2215/0034 , B01F2215/0073 , C12M23/14 , C12M27/02
摘要： A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.
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公开(公告)号：US09744507B2
公开(公告)日：2017-08-29
申请号：US14440376
申请日：2013-11-05
发明人： Martin Morrissey , Brian Pereira
CPC分类号： B01F15/0085 , B01F7/00241 , B01F13/0827 , B01F15/00487 , B01F2215/0034 , B01F2215/0073 , C12M23/14 , C12M27/02
摘要： A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.
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公开(公告)号：US09046292B2
公开(公告)日：2015-06-02
申请号：US13654595
申请日：2012-10-18
发明人： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
CPC分类号： F25D29/00 , A01N1/0263 , F25D2331/802 , F25D2400/28 , F25D2400/30 , F25D2600/06 , F25D2700/12 , Y10T29/53
摘要： The biocontainer of the present invention provides a low cost, simple solution of many of the problems encountered during shipping, freezing and thawing of biopharmaceutical materials. The present invention enables a user to monitor the temperature profile of each biopharmaceutical container during the cryogenic process, so as to ensure the integrity of materials within each biocontainer by using a pre-installed and pre-sterilized temperature sensor. In some embodiments, the sensor assembly includes a wireless transmitter and is capable of transmitting information regarding the measured reading. In other embodiments, the sensor assembly includes a processing unit, which determines whether the temperature profile is acceptable. In a further embodiment, an indicator is included, such that the processing unit may indicate whether the biopharmaceutical material has been properly frozen. In other embodiments, the sensor assembly also includes a storage element, which is capable of storing various parameters during the freezing process.
摘要翻译： 本发明的生物容器提供了在生物药物材料的运输，冷冻和解冻期间遇到的许多问题的低成本，简单的解决方案。 本发明使得用户能够在低温过程期间监测每个生物药物容器的温度曲线，以便通过使用预先安装和预灭菌的温度传感器来确保每个生物容器内的材料的完整性。 在一些实施例中，传感器组件包括无线发射器，并且能够发送关于测量读数的信息。 在其他实施例中，传感器组件包括处理单元，其确定温度分布是否可接受。 在另一实施例中，包括指示器，使得处理单元可以指示生物药物材料是否已被适当地冷冻。 在其他实施例中，传感器组件还包括存储元件，其能够在冷冻过程期间存储各种参数。
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公开(公告)号：US09027356B2
公开(公告)日：2015-05-12
申请号：US13654593
申请日：2012-10-18
发明人： Aaron Burke , Michael Felo , Brian Pereira , Elias Noukas , Dennis Wong
CPC分类号： F25D29/00 , A01N1/0263 , F25D2331/802 , F25D2400/28 , F25D2400/30 , F25D2600/06 , F25D2700/12 , Y10T29/53
摘要： The biocontainer of the present invention provides a low cost, simple solution of many of the problems encountered during shipping, freezing and thawing of biopharmaceutical materials. The present invention enables a user to monitor the temperature profile of each biopharmaceutical container during the cryogenic process, so as to ensure the integrity of materials within each biocontainer by using a pre-installed and pre-sterilized temperature sensor. In some embodiments, the sensor assembly includes a wireless transmitter and is capable of transmitting information regarding the measured reading. In other embodiments, the sensor assembly includes a processing unit, which determines whether the temperature profile is acceptable. In a further embodiment, an indicator is included, such that the processing unit may indicate whether the biopharmaceutical material has been properly frozen. In other embodiments, the sensor assembly also includes a storage element, which is capable of storing various parameters during the freezing process.
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