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公开(公告)号:US09744507B2
公开(公告)日:2017-08-29
申请号:US14440376
申请日:2013-11-05
发明人: Martin Morrissey , Brian Pereira
CPC分类号: B01F15/0085 , B01F7/00241 , B01F13/0827 , B01F15/00487 , B01F2215/0034 , B01F2215/0073 , C12M23/14 , C12M27/02
摘要: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.
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公开(公告)号:US09482351B2
公开(公告)日:2016-11-01
申请号:US13972301
申请日:2013-08-21
IPC分类号: A61M5/00 , F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , F16K3/26 , F16K17/40 , F16K15/18 , F16L37/107
CPC分类号: F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要: The present invention relates to a process for the sterile transfer of fluids, be they liquids or gases. It uses a presterilized device comprised of a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to a downstream component such as a filter, pipeline, sample bag and the like. The plunger has corresponding first and second ends. The first end of the plunger when it the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components. The device is attached to an upstream component and the face and the first end of the plunger are steam sterilized in place.
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公开(公告)号:US20130334450A1
公开(公告)日:2013-12-19
申请号:US13972301
申请日:2013-08-21
IPC分类号: F16K5/00
CPC分类号: F16K5/00 , A61M39/10 , A61M39/16 , A61M39/18 , A61M39/22 , A61M2039/1027 , A61M2039/222 , F16K3/265 , F16K13/04 , F16K15/18 , F16L37/107
摘要: The present invention relates to a process for the sterile transfer of fluids, be they liquids or gases. It uses a presterilized device comprised of a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger. The body has a first and a second end. The first end contains a face designed to be attached to the upstream component. The second end is connected to a downstream component such as a filter, pipeline, sample bag and the like. The plunger has corresponding first and second ends. The first end of the plunger when it the closed position is in alignment with the face of the body which combined form a steamable surface and a sterile barrier against the environment to the rest of the interior of the body, the plunger and downstream components. The device is attached to an upstream component and the face and the first end of the plunger are steam sterilized in place.
摘要翻译: 本发明涉及一种无菌转移流体(无论是液体还是气体)的方法。 它使用由具有通过其内部的至少一部分形成的孔的主体构成的预灭菌装置。 孔内包含一个可移动的柱塞。 身体有第一和第二端。 第一端包含设计成连接到上游部件的面。 第二端连接到诸如过滤器,管道,样品袋等的下游部件。 柱塞具有相应的第一和第二端。 柱塞在其关闭位置时的第一端与主体的表面对齐,该表面组合形成一个可蒸汽表面,并且一个无菌隔离物抵抗环境的内部其余部分,柱塞和下游部件。 该装置连接到上游部件,柱塞的表面和第一端被蒸汽灭菌就位。
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公开(公告)号:US20200182387A1
公开(公告)日:2020-06-11
申请号:US16315045
申请日:2017-05-23
发明人: Martin Morrissey
IPC分类号: F16L33/22
摘要: A clamp device for a barb member having a barbed region for disposing within an end of a flexible tube having an outer surface. The clamp device includes a flexible member including a body having a plurality of finger members compressible between a first resting position and a second clamping position; at least one of the flexible finger members having a radially inwardly extending tooth; the body having a through bore and an outer surface comprising threads; the flexible member being slidable over the barbed region and the outer surface of the flexible tube; a compression member having a body having a through bore and an inner surface including threads; the compression member being slidable over the flexible member; wherein upon threadingly engaging the compression member with the flexible member, the compression member compresses the finger member against the barb member.
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公开(公告)号:US09993785B2
公开(公告)日:2018-06-12
申请号:US15791869
申请日:2017-10-24
发明人: Martin Morrissey , Brian Pereira
CPC分类号: B01F15/0085 , B01F7/00241 , B01F13/0827 , B01F15/00487 , B01F2215/0034 , B01F2215/0073 , C12M23/14 , C12M27/02
摘要: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.
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公开(公告)号:US09827541B1
公开(公告)日:2017-11-28
申请号:US15658503
申请日:2017-07-25
发明人: Martin Morrissey , Brian Pereira
CPC分类号: B01F15/0085 , B01F7/00241 , B01F13/0827 , B01F15/00487 , B01F2215/0034 , B01F2215/0073 , C12M23/14 , C12M27/02
摘要: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.
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公开(公告)号:US20220184599A1
公开(公告)日:2022-06-16
申请号:US17609008
申请日:2020-08-06
发明人: Martin Morrissey , Conor King , Philip Borozenets
摘要: An apparatus for use with an isolator, including a crown for releasably joining with a beta port of the isolator, wherein the crown includes at least one anchoring support; a spring hook on at least one end of the at least one anchoring support; a needle block including at least one through hole for having a needle positioned therein, wherein the at least one needle is joined with tubing; a yoke; and a biasing element releasably joined with the yoke and the at least one anchoring support; wherein the needle block is releasably joined to the crown.
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公开(公告)号:US20210238536A1
公开(公告)日:2021-08-05
申请号:US16330413
申请日:2017-10-23
发明人: Martin Morrissey
摘要: Containers for separating microcarriers from a cell culture fluid that offer a greater efficiency of filtration of cell culture fluids containing microcarriers relative to systems described in the art. The container may include a first compartment that may include a sterile collapsible bag, an inlet port providing a fluid path into the first compartment and an outlet port providing a fluid path exiting the first compartment; and a second compartment fluidly connected with the inlet port of the first compartment and including a plurality of independent or discrete microcarrier receiving regions defined by boundary walls which are partially or fully porous and having a porosity sufficient to retain the microcarriers inside the second compartment, while allowing the cell culture fluid to pass through the second compartment into the outlet port of the first compartment, where the cell culture fluid can be collected.
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公开(公告)号:US20180043322A1
公开(公告)日:2018-02-15
申请号:US15791869
申请日:2017-10-24
发明人: Martin Morrissey , Brian Pereira
CPC分类号: B01F15/0085 , B01F7/00241 , B01F13/0827 , B01F15/00487 , B01F2215/0034 , B01F2215/0073 , C12M23/14 , C12M27/02
摘要: A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.
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公开(公告)号:US09494259B2
公开(公告)日:2016-11-15
申请号:US14074815
申请日:2013-11-08
发明人: Martin Morrissey , Neil Schauer
CPC分类号: F16L9/00 , B01J19/0093 , B01J2219/00783 , B01J2219/00808 , B01J2219/00813 , B01J2219/00833 , B01J2219/00968 , B01L3/502707 , B01L3/502715 , B01L3/561 , B01L2200/027 , B01L2200/0689 , B01L2300/0887 , F16L9/127 , F16L9/133 , F16L9/22 , Y10T137/87153
摘要: A disposable flow path having a manifold system that provides pressure resistance for the disposable device. The disposable device is comprised of a first rigid plastic sheet and a second rigid plastic sheet. Each sheet has two major surfaces and a thickness between them. At least one sheet surface has flow channels formed in it. The flow channels extend away from a first major surface and beyond the normal plane of a second major surface of the sheet. The sheets are liquid tightly sealed to each other at their adjoining first major surfaces. When each sheet contains a flow channel, the flow channels are aligned and in register with each other. One or more fittings can be secured in the flow channel(s) at an edge of the two liquid tightly sealed sheets. Alternatively, tubing is placed in the channels before the sheets are secured to one another.
摘要翻译: 一次性流路,其具有为一次性装置提供耐压性的歧管系统。 一次性装置包括第一刚性塑料片和第二刚性塑料片。 每片具有两个主表面和它们之间的厚度。 至少一个片材表面上形成有流动通道。 流动通道远离第一主表面并超过板的第二主表面的法线平面。 片材在相邻的第一主要表面彼此液体密封。 当每个纸张包含流动通道时,流动通道对齐并彼此对准。 一个或多个配件可以固定在两个液密封片的边缘处的流动通道中。 或者,在片彼此固定之前,将管道放置在通道中。
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