中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

7 records (took 0.015 seconds)

    HIGH CAPACITY COMPOSITE DEPTH FILTER MEDIA WITH LOW EXTRACTABLES
    1.
    发明申请
    HIGH CAPACITY COMPOSITE DEPTH FILTER MEDIA WITH LOW EXTRACTABLES 有权

    公开(公告)号：US20220387917A1

    公开(公告)日：2022-12-08

    申请号：US17819969

    申请日：2022-08-16

    Applicant: EMD Millipore Corporation

    Inventor： Maybelle Woo ,  David Yavorsky ,  John Amara ,  Nripen Singh ,  Kwok-Shun Cheng

    IPC: B01D39/16 ,  B01D29/66

    Abstract: A depth filtration device for the clarification of biological fluids including a composite depth filter media having a nonwoven first layer integral with a second layer containing a polyacrylonitrile (PAN) fibers, a filter aid, and a wet-strength resin. The depth filter media exhibits increased binding capacity for soluble impurities such as DNA and host cell proteins from biological/cell culture feedstreams during secondary clarification and low-level impurity clearance of harvested cell culture fluids, such as those used for the manufacture of monoclonal antibodies. The depth filter media additionally exhibits significantly lower flushing requirements, resulting in lower levels of organic, inorganic and bioburden extractables released, high dirt holding capacities and good chemical and/or radiation resistance.

    HIGH CAPACITY COMPOSITE DEPTH FILTER MEDIA WITH LOW EXTRACTABLES
    2.
    发明申请
    HIGH CAPACITY COMPOSITE DEPTH FILTER MEDIA WITH LOW EXTRACTABLES 审中-公开
    高容量复合深度过滤介质与低提取物

    公开(公告)号：US20160114272A1

    公开(公告)日：2016-04-28

    申请号：US14890774

    申请日：2014-09-02

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： Maybelle Woo ,  David Yavorksy ,  John Amara ,  Nripen Singh

    IPC: B01D39/16 ,  B01D29/66

    CPC classification number: B01D39/1623 ,  B01D29/66 ,  B01D39/163 ,  B01D2239/0407 ,  B01D2239/0654 ,  B01D2239/086

    Abstract: A depth filtration device for the clarification of biological fluids including a composite depth filter media having a nonwoven first layer integral with a second layer containing a polyaeryionitrile (PAN) fibers, a filter aid, and a wet-strength resin. The depth filter media exhibits increased creased binding capacity for soluble impurities such as DNA and host cells proteins from biological/cell culture feed-streams during secondary clarification and low-level impurity clearance of harvested cell culture fluids, such as those used for the manufacture of monoclonal antibodies. The depth filter media additionally exhibits significantly lower flushing requirements, resulting in lower levels of organic, inorganic and bioburden extractables released, high dirt holding capacities and good chemical and/or radiation resistance.

    Abstract translation: 一种用于澄清生物流体的深度过滤装置，包括具有与包含聚噻吩（PAN）纤维的第二层成一体的非织造第一层的复合深度过滤介质，助滤剂和湿强度树脂。 深度过滤介质在二次澄清过程中生物/细胞培养物料流中的可溶性杂质如DNA和宿主细胞蛋白质的增加的结合能力增加，并且收集的细胞培养液的低含量杂质清除，例如用于制造 单克隆抗体。 深度过滤介质还显示出显着降低的冲洗要求，导致释放的有机，无机和生物负载提取物水平较低，高污垢保持能力以及良好的化学和/或耐辐射性。

    High capacity composite depth filter media with low extractables
    6.
    发明授权
    High capacity composite depth filter media with low extractables 有权

    公开(公告)号：US11590439B2

    公开(公告)日：2023-02-28

    申请号：US14890774

    申请日：2014-09-02

    Applicant: EMD Millipore Corporation

    Inventor： Maybelle Woo ,  David Yavorksy ,  John Amara ,  Nripen Singh ,  Kwok-Shun Cheng

    IPC: B01D39/16 ,  B01D29/66

    Abstract: A depth filtration device for the clarification of biological fluids including a composite depth filter media having a nonwoven first layer integral with a second layer containing a polyaeryionitrile (PAN) fibers, a filter aid, and a wet-strength resin. The depth filter media exhibits increased creased binding capacity for soluble impurities such as DNA and host eel! proteins from biological/cell culture feed-streams during secondary clarification and low-level impurity clearance of harvested cell culture fluids, such as those used for the manufacture of monoclonal antibodies. The depth filter media additionally exhibits significantly lower flushing requirements, resulting in lower levels of organic, inorganic and bioburden extractables released, high dirt holding capacities and good chemical and/or radiation resistance.

    High capacity composite depth filter media with low extractables
    7.
    发明授权
    High capacity composite depth filter media with low extractables 有权

    公开(公告)号：US11439933B2

    公开(公告)日：2022-09-13

    申请号：US16720102

    申请日：2019-12-19

    Applicant: EMD Millipore Corporation

    Inventor： Maybelle Woo ,  David Yavorsky ,  John Amara ,  Nripen Singh ,  Kwok-Shun Cheng

    IPC: B01D39/16 ,  B01D29/66

    Abstract: A depth filtration device for the clarification of biological fluids including a composite depth filter media having a nonwoven first layer integral with a second layer containing a polyacrylonitrile (PAN) fibers, a filter aid, and a wet-strength resin. The depth filter media exhibits increased binding capacity for soluble impurities such as DNA and host cell proteins from biological/cell culture feedstreams during secondary clarification and low-level impurity clearance of harvested cell culture fluids, such as those used for the manufacture of monoclonal antibodies. The depth filter media additionally exhibits significantly lower flushing requirements, resulting in lower levels of organic, inorganic and bioburden extractables released, high dirt holding capacities and good chemical and/or radiation resistance.

Patent Agency Ranking