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    Primarily niobium stent
    5.
    发明授权
    Primarily niobium stent 失效
    主要是铌支架

    公开(公告)号：US07604703B2

    公开(公告)日：2009-10-20

    申请号：US11417856

    申请日：2006-05-03

    申请人： Torsten Scheuermann ,  Eckhard Alt

    发明人： Torsten Scheuermann ,  Eckhard Alt

    IPC分类号： C23C8/06 ,  A61F2/06 ,  C22F1/18

    CPC分类号： A61L31/18 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2310/00598 ,  A61L31/022 ,  A61L31/088

    摘要： In a process of fabricating a stent composed primarily of niobium alloyed with a trace amount of zirconium, tantalum, or titanium for hardening, the stent is annealed under vacuum in a substantially oxygen-free environment. The vacuum is preferably maintained at pressure less than 10−4 millibars, oxygen-content less than about 80 parts per million, and the annealing temperature exceeds 400° C. for at least one hour, and is preferably kept in a range from about 1100-1200° C. for several hours. This may be followed by applying a surface layer of oxide, such as iridium oxide, with a thickness of 299-300 nm to the stent.

    摘要翻译： 在制造主要由铌合金化的用于硬化的锆，钽或钛的支架的制造过程中，支架在基本上无氧的环境中在真空下退火。 真空优选保持在小于10-4毫巴的压力，含氧量小于约百万分之八十，退火温度超过400℃至少一小时，优选保持在约1100 -1200℃几个小时。 然后可以向支架施加厚度为299-300nm的氧化物表面层，例如氧化铱。

    Primarily niobium stent
    8.
    发明申请
    Primarily niobium stent 失效
    主要是铌支架

    公开(公告)号：US20060196581A1

    公开(公告)日：2006-09-07

    申请号：US11417856

    申请日：2006-05-03

    申请人： Torsten Scheuermann ,  Eckhard Alt

    发明人： Torsten Scheuermann ,  Eckhard Alt

    IPC分类号： C23C8/06

    CPC分类号： A61L31/18 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2310/00598 ,  A61L31/022 ,  A61L31/088

    摘要： In a process of fabricating a stent composed primarily of niobium alloyed with a trace amount of zirconium, tantalum, or titanium for hardening, the stent is annealed under vacuum in a substantially oxygen-free environment. The vacuum is preferably maintained at pressure less than 10−4 millibars, oxygen-content less than about 80 parts per million, and the annealing temperature exceeds 400° C. for at least one hour, and is preferably kept in a range from about 1100-1200° C. for several hours. This may be followed by applying a surface layer of oxide, such as iridium oxide, with a thickness of 299-300 nm to the stent.

    摘要翻译： 在制造主要由铌合金化的用于硬化的锆，钽或钛的支架的制造过程中，支架在基本上无氧的环境中在真空下退火。 真空优选保持在小于10 -4毫巴的压力下，含氧量小于约百万分之八十，退火温度超过400℃至少一小时，优选 保持在约1100-1200℃的范围内几个小时。 然后可以向支架施加厚度为299-300nm的氧化物表面层，例如氧化铱。

    Primarily niobium stent
    9.
    发明授权
    Primarily niobium stent 有权

    公开(公告)号：US07101391B2

    公开(公告)日：2006-09-05

    申请号：US10232774

    申请日：2002-08-31

    申请人： Torsten Scheuermann ,  Eckhard Alt

    发明人： Torsten Scheuermann ,  Eckhard Alt

    IPC分类号： A61F2/06

    CPC分类号： A61L31/18 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2310/00598 ,  A61L31/022 ,  A61L31/088

    摘要： In a process of fabricating a stent composed primarily of niobium alloyed with a trace amount of zirconium, tantalum, or titanium for hardening, the stent is annealed under vacuum in a substantially oxygen-free environment. The vacuum is preferably maintained at pressure less than 10−4 millibars, oxygen-content less than about 80 parts per million, and the annealing temperature exceeds 400° C. for at least one hour, and is preferably kept in a range from about 1100–1200° C. for several hours. This may be followed by applying a surface layer of oxide, such as iridium oxide, with a thickness of 299–300 nm to the stent.

    Surface treated bioerodible metal endoprostheses
    10.
    发明授权
    Surface treated bioerodible metal endoprostheses 失效
    表面处理的生物腐蚀性金属内假体

    公开(公告)号：US08668732B2

    公开(公告)日：2014-03-11

    申请号：US13053791

    申请日：2011-03-22

    申请人： Torsten Scheuermann ,  Jan Weber ,  Charles Deng ,  Jonathan S. Stinson ,  Steven R. Larsen ,  Dennis A. Boismier ,  Jacob D. Edick

    发明人： Torsten Scheuermann ,  Jan Weber ,  Charles Deng ,  Jonathan S. Stinson ,  Steven R. Larsen ,  Dennis A. Boismier ,  Jacob D. Edick

    IPC分类号： A61F2/82

    CPC分类号： A61L31/148 ,  A61F2/91 ,  A61F2210/0004 ,  A61L31/022 ,  A61L31/088

    摘要： An endoprosthesis includes an expandable tubular body defined by a plurality of struts. In some embodiments, the expandable tubular body includes a bioerodible metal that has at least a first surface region and a second surface region. The first and second surface regions can have different surface oxide compositions. In some embodiments, the first portion has a thermally altered microstructure and the second portion has a wrought microstructure. The thermally altered microstructure can be a cast microstructure comprising dendritic grains. The first portion forms at least a portion of an outer surface of the expandable tubular body. In some embodiments, the expandable tubular body includes iron or a bioerodible iron alloy and at least one surface of the expandable tubular body includes a substantially uniform coating of iron(III) oxide.

    摘要翻译： 内假体包括由多个支柱限定的可扩张管状体。 在一些实施例中，可扩张管状体包括具有至少第一表面区域和第二表面区域的生物浸渍金属。 第一和第二表面区域可以具有不同的表面氧化物组成。 在一些实施例中，第一部分具有热改变的微结构，第二部分具有锻造微结构。 热改变的微结构可以是包含树枝状晶粒的铸造微结构。 第一部分形成可扩张管状体的外表面的至少一部分。 在一些实施例中，可膨胀管状体包括铁或生物腐蚀性铁合金，并且可膨胀管体的至少一个表面包括基本均匀的氧化铁（III）涂层。