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公开(公告)号：US4155909A
公开(公告)日：1979-05-22
申请号：US805689
申请日：1977-06-13
IPC分类号： A01N43/40 , C07D207/16 , C07D213/36 , C07D213/38 , C07D213/54 , C07D213/57 , C07D401/02
CPC分类号： C07D213/38 , A01N43/40 , C07D207/16 , C07D213/36 , C07D213/54 , C07D213/57
摘要： The invention relates to 2-alkyl nicotinoids and improved methods for producing them.
摘要翻译： {PG，1本发明涉及2-烷基烟碱类及其制备方法。
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公开(公告)号：US4220781A
公开(公告)日：1980-09-02
申请号：US972161
申请日：1978-12-21
IPC分类号： A01N43/40 , C07D207/16 , C07D213/36 , C07D213/38 , C07D213/54 , C07D213/57 , C07D401/04
CPC分类号： C07D213/38 , A01N43/40 , C07D207/16 , C07D213/36 , C07D213/54 , C07D213/57
摘要： The invention relates to 2-alkyl nicotinoids and improved methods for producing them.
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公开(公告)号：US5138062A
公开(公告)日：1992-08-11
申请号：US618913
申请日：1990-11-28
IPC分类号： C07D207/06 , C07D213/38 , C07D401/04
CPC分类号： C07D401/04 , C07D207/06 , C07D213/38
摘要： This invention provides a class of nicotine analogs which as therapeutic agents exhibit tranquilizing effects in mammals.Illustrative of an invention nicotine analog is 3-[N-methyl-N-(3-aminopropyl)]aminomethylpyridine ##STR1## the nicotine analogs can exist in the form of acid addition salts.
摘要翻译： 本发明提供了一类尼古丁类似物，其作为治疗剂在哺乳动物中表现出镇静作用。 尼古丁类似物的实例是3- [N-甲基-N-（3-氨基丙基）]氨基甲基吡啶，尼古丁类似物可以以酸加成盐的形式存在。
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4.发明授权
公开(公告)号：US5230802A
公开(公告)日：1993-07-27
申请号：US902426
申请日：1992-06-24
CPC分类号： B01D61/246 , B01D11/0415 , C07C69/70
摘要： This invention provides novel organic acids which exhibit utility as liquid ion exchanges suitable for use in an invention solvent extraction process. Illustrative of an invention organic acid is a compound corresponding to the formula: ##STR1## where each of R.sub.1 and R.sub.2 is a C.sub.3 -C.sub.16 branched alkyl group.
摘要翻译： 本发明提供新的有机酸，其表现出适用于本发明溶剂萃取方法中的液体离子交换的用途。 有机酸的例子是对应于下式的化合物：其中R 1和R 2各自为C 3 -C 16支链烷基。
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5.发明授权
公开(公告)号：US5080719A
公开(公告)日：1992-01-14
申请号：US100694
申请日：1987-09-24
IPC分类号： A24B3/12 , A24B15/28 , A24B15/38 , C07D241/12
CPC分类号： C07D241/12 , A24B15/281 , A24B15/38
摘要： This invention privdes novel heteroaromatic compounds, and smoking compositions which contain an invention heteroaromatic compound as a flavorant-release additive as illustrated by the following additive structure: ##STR1## Under typical cigarette smoking conditions, 2-isopropylpyrazine and acetophenone are released as pyrolysis products, and enhance the flavor and aroma of the mainstream and sidestream smoke.
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公开(公告)号：US5015741A
公开(公告)日：1991-05-14
申请号：US416523
申请日：1989-10-03
IPC分类号： C07D211/14 , C07D207/06 , C07D213/36 , C07D213/38 , C07D401/04
CPC分类号： C07D401/04 , C07D207/06 , C07D213/38
摘要： This invention provides a novel class of nicotine analogs which as therapeutic agents exhibit tranquilizing effects in mammals.Illustrative of invention nicotine analogs are 1-(3-dimethylaminopropyl)-2-(3-pyridyl)pyrrolidine: ##STR1## and (R,S)-6-(N,N-dimethyl-3-aminopropyl)nicotine: ##STR2## The nicotine analogs can exist in the form of acid addition salts.
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公开(公告)号：US4163855A
公开(公告)日：1979-08-07
申请号：US889147
申请日：1978-03-23
IPC分类号： C07D213/34 , C07D213/38 , C07D213/55 , C07D401/02
CPC分类号： C07D213/34 , C07D213/38 , C07D213/55
摘要： Novel azetidine, and particularly 2-pyridyl-azetidine, compounds are disclosed. These compounds are produced from amino-esters by a sequence comprising conversion to the sulfonamide, reduction of the ester to the alcohol, sulfonation of the resultant alcohol and cylization to the N-sulfonylazetidine. This azetidine compound may then be transformed, as desired, to various N-derivatives by substitution of hydrogen or other univalent organic groups on the secondary amine of the azetidine ring.
摘要翻译： 公开了新的氮杂环丁烷，特别是2-吡啶基 - 氮杂环丁烷化合物。 这些化合物由氨基酯通过包括转化为磺酰胺，将酯还原成醇，磺化所得醇并向N-磺酰基氮杂环丁烷烷基化的顺序由氨基酯制备。 然后可以根据需要将该氮杂环丁烷化合物通过取代氮杂环丁烷的仲胺上的氢或其它一价有机基团而转化为各种N-衍生物。
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公开(公告)号：US4163856A
公开(公告)日：1979-08-07
申请号：US889188
申请日：1978-03-23
IPC分类号： C07D213/34 , C07D213/38 , C07D213/55 , C07D401/02
CPC分类号： C07D213/38 , C07D213/34 , C07D213/55
摘要： Novel azetidine, and particularly 3-pyridyl-azetidine, compounds are disclosed. These compounds are produced from .gamma.-amino alcohols by a sequence comprising disulfonation to produce the sulfonamido-alkylsulfonate and then cyclization to the N-sulfonylazetidine. These azetidine compounds may then be transformed, as desired, to various N-derivatives by substitution of hydrogen or other univalent organic groups on the secondary amine of the azetidine ring.
摘要翻译： 公开了新的氮杂环丁烷，特别是3-吡啶基 - 氮杂环丁烷。 这些化合物由γ-氨基醇通过包含二磺化产生亚磺酰氨基 - 烷基磺酸酯的顺序产生，然后环化成N-磺酰基氮杂环丁烷。 然后可以根据需要将这些氮杂环丁烷化合物通过取代氮杂环丁烷的仲胺上的氢或其它一价有机基团而转化为各种N-衍生物。
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公开(公告)号：US4216329A
公开(公告)日：1980-08-05
申请号：US590669
申请日：1975-06-26
申请人： Henry V. Secor
发明人： Henry V. Secor
IPC分类号： C07D213/34 , C07D213/38 , C07D213/55 , C07C85/08
CPC分类号： C07D213/55 , C07D213/34 , C07D213/38
摘要： A process for the production of .gamma.-amino alcohols from .beta.-dicarbonyl compounds is disclosed. The dicarbonyls are reacted with alkoxyamines and the resultant alkoximino compounds reduced to yield .gamma.-amino alcohols. Also described are novel substituted .gamma.-amino alcohols.
摘要翻译： 公开了从β-二羰基化合物制备γ-氨基醇的方法。 二羰基与烷氧基胺反应，并将所得的烷基肟基化合物还原得到γ-氨基醇。 还描述了新的取代的γ-氨基醇。
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