公开(公告)号：US4757144A

公开(公告)日：1988-07-12

申请号：US913621

申请日：1986-09-30

Applicant: Kazuhiko Okabe ,  Yukinaga Yokota ,  Kazuhito Matsutani ,  Tatuhiro Imanaka

Inventor： Kazuhiko Okabe ,  Yukinaga Yokota ,  Kazuhito Matsutani ,  Tatuhiro Imanaka

IPC: C07B61/00 ,  B01J23/00 ,  B01J23/40 ,  C07B43/04 ,  C07C67/00 ,  C07C209/00 ,  C07C209/26 ,  C07C211/09 ,  C07C211/17 ,  C07C211/22 ,  C07C213/02 ,  C07C215/12 ,  C07D295/12 ,  C07C85/08 ,  C07C87/127 ,  C07C87/14 ,  C07C87/28

CPC classification number: C07C209/26 ,  C07C211/08 ,  C07C211/12 ,  C07C211/34 ,  C07C213/08 ,  C07C215/12 ,  C07D295/13 ,  B01J23/42 ,  B01J23/44

Abstract: A tertiary amine is effectively prepared by reacting a primary or secondary amine with formaldehyde in the presence of a palladium or platinum catalyst at a hydrogen pressure of 3 to 50 kg/cm2 (gauge pressure) at a temperature of 80.degree. to 180.degree. C., by controlling the addition of formaldehyde to the starting amine.

Abstract translation: 在钯或铂催化剂的存在下，在氢压为3〜50kg / cm 2（表压）下，在80〜180℃的温度下，使伯胺或仲胺与甲醛反应，可有效制备叔胺。 ，通过控制向起始胺中加入甲醛。

公开(公告)号：US4625063A

公开(公告)日：1986-11-25

申请号：US741979

申请日：1985-06-06

Applicant: Yukinaga Yokota ,  Yuji Sawamoto ,  Hideki Taniguchi ,  Kazuhiko Okabe

Inventor： Yukinaga Yokota ,  Yuji Sawamoto ,  Hideki Taniguchi ,  Kazuhiko Okabe

IPC: B01J23/90 ,  C07B61/00 ,  C07C67/00 ,  C07C209/00 ,  C07C209/14 ,  C07C209/16 ,  C07C209/24 ,  C07C209/26 ,  C07C211/03 ,  C07C211/08 ,  C07C85/06 ,  C07C85/08

CPC classification number: C07C209/26 ,  C07C209/14 ,  C07C209/16 ,  C07C211/08

Abstract: A tertiary amine of a high purity is prepared from an alcohol or an aldehyde and a primary or second amine at a low temperature, using a catalyst of copper, nickel and an element belonging to the VIII platinum group such as platinum, palladium, ruthenium and rhodium, while removing out water formed by the reaction.

Abstract translation: 使用铜，镍和属于VIII铂族的元素如铂，钯，钌的催化剂，在低温下由醇或醛和伯或仲胺制备高纯度的叔胺， 铑，同时除去由反应形成的水。

公开(公告)号：US4540821A

公开(公告)日：1985-09-10

申请号：US228436

申请日：1981-01-26

Applicant: John M. Larkin ,  Ernest L. Yeakey ,  Lewis W. Watts, Jr.

Inventor： John M. Larkin ,  Ernest L. Yeakey ,  Lewis W. Watts, Jr.

IPC: C07C85/08

CPC classification number: C07C213/02

Abstract: A process for the manufacture of aminopolyols and polyaminopolyols by continuous reductive amination of sugars in aqueous solution is described. Syrups such as corn syrups may be used directly for this process. It has been found that the lower the mol ratio of NH.sub.3 to the sugar, with a ratio of 1 as the lower limit, the higher is the degree of nitrogen incorporation into the sugar. It is essential that the streams of ammonia and aqueous sugar solution be pumped to the reaction zone separately.

Abstract translation: 描述了通过在水溶液中连续还原胺化糖来制备氨基多元醇和多氨基多元醇的方法。 糖浆如玉米糖浆可以直接用于该过程。 已经发现，NH 3与糖的摩尔比越低，比例为1作为下限，氮掺入糖的程度越高。 必须将氨水和糖水溶液分别泵入反应区。

公开(公告)号：US4521624A

公开(公告)日：1985-06-04

申请号：US601032

申请日：1984-04-16

Applicant: Philip F. Jackisch

Inventor： Philip F. Jackisch

IPC: C07C209/26 ,  C07C211/35 ,  C07C85/00 ,  C07C85/08

CPC classification number: C07C209/26 ,  C07C2101/14

Abstract: Process for preparing cyclic amines by the reductive amination of saturated cyclic ketones. For example, cyclohexanone is reductively aminated to obtain N,N-dimethylcyclohexylamine.

Abstract translation: 通过饱和环酮的还原胺化制备环胺的方法。 例如，将环己酮还原胺化得到N，N-二甲基环己胺。

公开(公告)号：US4404404A

公开(公告)日：1983-09-13

申请号：US328641

申请日：1981-12-09

Applicant: Harold E. Swift ,  Robert A. Innes ,  Anatoli Onopchenko

Inventor： Harold E. Swift ,  Robert A. Innes ,  Anatoli Onopchenko

IPC: B01J23/78 ,  B01J31/28 ,  C07C85/06 ,  C07C85/08

CPC classification number: B01J31/26 ,  B01J23/78 ,  B01J31/04 ,  B01J31/28 ,  B01J2231/4283 ,  B01J2531/847 ,  B01J31/2234

Abstract: A process for producing aliphatic amines which comprises reacting an aliphatic alcohol or an aliphatic aldehyde with an aminating agent selected from the group consisting of ammonia, a primary amine and a secondary amine in the liquid phase in the presence of an unsupported catalyst consisting essentially of (1) copper oxide or copper hydroxide and (2) a Group II A metal oxide or hydroxide. In a preferred embodiment the catalyst system also contains an organo nickel compound.

Abstract translation: 一种制备脂族胺的方法，其包括使脂族醇或脂族醛与在液相中的氨，胺和仲胺的胺化剂在无载体催化剂存在下反应，所述催化剂基本上由（ 1）氧化铜或氢氧化铜和（2）IIA族金属氧化物或氢氧化物。 在优选的实施方案中，催化剂体系还含有有机镍化合物。

公开(公告)号：US4299985A

公开(公告)日：1981-11-10

申请号：US217287

申请日：1980-12-16

Applicant: John F. Knifton ,  Philip H. Moss

Inventor： John F. Knifton ,  Philip H. Moss

IPC: C07C45/50 ,  C07C209/60 ,  C07C85/08

CPC classification number: C07C209/60 ,  C07C45/50

Abstract: This invention concerns the synthesis of linear alkyl primary amines from a-olefins via an oxoamination process comprising (a) hydrogen and carbon monoxide addition to olefinic substrates to obtain aldehyde-containing compounds in the presence of ligand-stabilized platinum(II) halide catalysts with Group IVB metal halide cocatalysts, and (b) reductive amination of said aldehydic intermediates in the presence of oxide-supported, nickel catalysts.

Abstract translation: 本发明涉及通过氧化沉淀法合成来自α-烯烃的直链烷基伯胺，该方法包括（a）在配体稳定的铂（II）卤化物催化剂存在下将氢和一氧化碳加入烯属底物以获得含醛化合物， IVB族金属卤化物助催化剂，和（b）在氧化物负载的镍催化剂存在下还原胺化所述醛中间体。

公开(公告)号：US4248801A

公开(公告)日：1981-02-03

申请号：US54457

申请日：1979-07-03

Applicant: Susumu Tomidokoro ,  Michito Sato ,  Daini Saika

Inventor： Susumu Tomidokoro ,  Michito Sato ,  Daini Saika

IPC: C07B61/00 ,  B01J23/00 ,  B01J29/00 ,  C07C67/00 ,  C07C209/00 ,  C07C209/48 ,  C07C209/60 ,  C07C209/68 ,  C07C209/70 ,  C07C211/03 ,  C07C85/08 ,  C07C85/20 ,  C07C85/24

CPC classification number: C07C209/70 ,  C07C209/48 ,  C07C209/68

Abstract: Tertiary monomethylamines having long chain alkyl groups are advantageously prepared from unsaturated aliphatic nitriles under a low pressure at a high yield by the steps of:(a) reducing the nitriles with hydrogen in the presence of a nickel hydrogenation catalyst at 200.degree. through 230.degree. C. and under a hydrogen pressure of 0 through 10 kg/cm.sup.2 G, while the formed ammonia is removed;(b) reacting the resultant amines with a hydroxymethylation agent in the presence of the nickel catalyst at 150.degree. through 180.degree. C., while hydrogen is passed through the reaction zone under 0.3 through 7 kg/cm.sup.2 G and the formed water is removed, and;(c) reducing the resultant tertiary amines with hydrogen in the presence of the nickel catalyst at 175.degree. through 210.degree. C. and under a hydrogen pressure of 5 through 10 kg/cm.sup.2 G.

Abstract translation: 具有长链烷基的三级单甲胺有利地由低不饱和脂族腈以高产率由以下步骤制备：（a）在镍加氢催化剂存在下，在200℃至230℃下，用氢还原腈 并在0至10kg / cm2G的氢气压力下，同时除去形成的氨; （b）使所得胺与羟甲基化试剂在镍催化剂存在下，在150℃至180℃下反应，同时使氢气在0.3至7kg / cm2G范围内通过反应区，除去形成的水， ; （c）在镍催化剂存在下，在175℃〜210℃，5〜10kg / cm2G的氢气压力下，用氢还原所得的叔胺。

公开(公告)号：US4215073A

公开(公告)日：1980-07-29

申请号：US43949

申请日：1979-05-30

Applicant: Boy Cornils ,  Werner Konkol ,  Gerhard Diekhaus ,  Ernst Wiebus

Inventor： Boy Cornils ,  Werner Konkol ,  Gerhard Diekhaus ,  Ernst Wiebus

IPC: B01J23/00 ,  C07C67/00 ,  C07C209/00 ,  C07C209/26 ,  C07C211/09 ,  C07C211/19 ,  C07C211/36 ,  C07C85/08

CPC classification number: C07C209/26 ,  C07C2103/68

Abstract: A two-step process for the production of aliphatic or cycloaliphatic diamines having 4 to 18 carbon atoms is disclosed wherein in the first step an aliphatic or cycloaliphatic dialdehyde is reacted with a monoamine olefin at atmospheric pressure at a temperature up to 100.degree. C. to form the corresponding diazomethyne and in the second step the diazomethyne is reacted at 60.degree. to 200.degree. C. and 50 to 300 bar with a mixture of ammonia and hydrogen in the presence of a hydrogenation catalyst to form the corresponding diamine and release of monoamine.

Abstract translation: 公开了用于制备具有4至18个碳原子的脂肪族或脂环族二胺的两步法，其中在第一步中，将脂族或脂环族二醛与单胺烯烃在大气压下在高达100℃的温度下反应至 形成相应的重氮甲炔，并且在第二步中，在氢化催化剂存在下，使用氨和氢气的混合物，在60至200℃和50至300巴之间使重氮甲炔反应形成相应的二胺和单胺的释放。

公开(公告)号：US4210602A

公开(公告)日：1980-07-01

申请号：US14673

申请日：1979-02-23

Applicant: Manfred Bergfeld ,  Hans G. Zengel

Inventor： Manfred Bergfeld ,  Hans G. Zengel

IPC: C07B61/00 ,  B01J21/18 ,  B01J23/00 ,  B01J23/44 ,  B01J27/00 ,  B01J27/04 ,  B01J27/045 ,  B01J35/10 ,  C07C20060101 ,  C07C67/00 ,  C07C209/00 ,  C07C209/26 ,  C07C209/38 ,  C07C209/40 ,  C07C209/54 ,  C07C211/53 ,  C07C211/54 ,  C07C85/08 ,  C07C85/11

CPC classification number: C07C209/26

Abstract: An improved process for the preparation of asymmetrical N-phenyl-N'-substituted para-phenylene diamines by the reductive alkylation of para-nitroso-diphenylhydroxylamine with an aldehyde or a ketone in the presence of hydrogen and a hydrogenation catalyst is disclosed. The improvement comprises utilizing as the hydrogenation catalyst (1) one member selected the group consisting of palladium and platinum sulfide, in an amount less than 1%, by weight, based on the weight of para-nitroso-diphenylhydroxylamine, and (2) activated carbon with a specific surface area of at least 700 square meters per gram and an ash content of less than 7.5%, by weight.

Abstract translation: 公开了通过在氢气和氢化催化剂的存在下用醛或酮还原烷基化对 - 亚硝基 - 二苯基羟胺来制备不对称N-苯基-N'-取代的对亚苯基二胺的改进方法。 改进之处在于，以对位亚硝基 - 二苯基羟胺的重量为基准，以1重量％的量使用一种选自钯和铂硫化物的氢化催化剂（1）和（2）活化的 碳比表面积至少为700平方米/克，灰分含量小于7.5重量％。

公开(公告)号：US4052456A

公开(公告)日：1977-10-04

申请号：US763967

申请日：1977-01-31

Applicant: Edward T. Marquis ,  Lewis W. Watts, Jr.

Inventor： Edward T. Marquis ,  Lewis W. Watts, Jr.

IPC: C07C85/08

CPC classification number: B01J23/30

Abstract: Covers a method of preparing diaminodiphenylmethanes and higher homologues thereof which comprises the step of condensing aniline and formaldehyde in the presence of an aluminum silicide catalyst.