公开(公告)号：US20060016156A1

公开(公告)日：2006-01-26

申请号：US11171814

申请日：2005-06-30

申请人： Edward Bush ,  Robert Nase ,  Hiroshi Togashi ,  Hubert Jansen ,  John Paproski

发明人： Edward Bush ,  Robert Nase ,  Hiroshi Togashi ,  Hubert Jansen ,  John Paproski

IPC分类号： B65B31/00 ,  B65B5/06

CPC分类号： B65B31/06 ,  A61M5/002 ,  A61M2207/00 ,  A61M2209/06 ,  B65B5/067 ,  B65D77/0446 ,  B65D81/203

摘要： A vacuum packaging system for transporting a plurality of medical containers including a tray that supports the medical containers and an air impervious flexible film defining an internal cavity. The air impervious flexible film completely surrounds the tray and the medical containers. The internal cavity is evacuated to a predetermined vacuum level below atmospheric pressure. A method for packaging the plurality of medical containers for transportation in the tray includes inserting the medical containers into the tray, inserting the tray filled with medical containers into the internal cavity, evacuating the internal cavity to a predetermined vacuum pressure and sealing the flexible film such that the predetermined vacuum pressure is generally maintained in the internal cavity.

摘要翻译： 一种用于运输多个医疗容器的真空包装系统，包括支撑医疗容器的托盘和限定内腔的不透气的柔性膜。 不透气的柔性膜完全包围托盘和医疗容器。 将内腔抽真空至低于大气压的预定真空度。 用于将多个用于在托盘中运输的医疗容器进行包装的方法包括将医疗容器插入托盘，将填充有医疗容器的托盘插入内腔中，将内腔排空到预定的真空压力并将柔性膜密封 预定的真空压力通常保持在内腔中。

公开(公告)号：US07428807B2

公开(公告)日：2008-09-30

申请号：US11680710

申请日：2007-03-01

申请人： Edward Vander Bush ,  Robert Nase ,  Hiroshi Togashi ,  Hubert Jansen ,  John Paproski

发明人： Edward Vander Bush ,  Robert Nase ,  Hiroshi Togashi ,  Hubert Jansen ,  John Paproski

IPC分类号： B65B55/02 ,  B65B31/04 ,  B65B21/24 ,  B65B53/00

CPC分类号： B65B31/06 ,  A61M5/002 ,  A61M2207/00 ,  A61M2209/06 ,  B65B5/067 ,  B65D77/0446 ,  B65D81/203

摘要： A vacuum packaging system for transporting a plurality of medical containers including a tray that supports the medical containers and an air impervious flexible film defining an internal cavity. The air impervious flexible film completely surrounds the tray and the medical containers. The internal cavity is evacuated to a predetermined vacuum level below atmospheric pressure. A method for packaging the plurality of medical containers for transportation in the tray includes inserting the medical containers into the tray, inserting the tray filled with medical containers into the internal cavity, evacuating the internal cavity to a predetermined vacuum pressure and sealing the flexible film such that the predetermined vacuum pressure is generally maintained in the internal cavity.

摘要翻译： 一种用于运输多个医疗容器的真空包装系统，包括支撑医疗容器的托盘和限定内腔的不透气的柔性膜。 不透气的柔性膜完全包围托盘和医疗容器。 将内腔抽真空至低于大气压的预定真空度。 用于将多个用于在托盘中运输的医疗容器进行包装的方法包括将医疗容器插入托盘，将填充有医疗容器的托盘插入内腔中，将内腔排空到预定的真空压力并将柔性膜密封 预定的真空压力通常保持在内腔中。

公开(公告)号：US20070157564A1

公开(公告)日：2007-07-12

申请号：US11680710

申请日：2007-03-01

申请人： Edward Vander Bush ,  Robert Nase ,  Hiroshi Togashi ,  Hubert Jansen ,  John Paproski

发明人： Edward Vander Bush ,  Robert Nase ,  Hiroshi Togashi ,  Hubert Jansen ,  John Paproski

IPC分类号： B65B31/00

CPC分类号： B65B31/06 ,  A61M5/002 ,  A61M2207/00 ,  A61M2209/06 ,  B65B5/067 ,  B65D77/0446 ,  B65D81/203

摘要： A vacuum packaging system for transporting a plurality of medical containers including a tray that supports the medical containers and an air impervious flexible film defining an internal cavity. The air impervious flexible film completely surrounds the tray and the medical containers. The internal cavity is evacuated to a predetermined vacuum level below atmospheric pressure. A method for packaging the plurality of medical containers for transportation in the tray includes inserting the medical containers into the tray, inserting the tray filled with medical containers into the internal cavity, evacuating the internal cavity to a predetermined vacuum pressure and sealing the flexible film such that the predetermined vacuum pressure is generally maintained in the internal cavity.

摘要翻译： 一种用于运输多个医疗容器的真空包装系统，包括支撑医疗容器的托盘和限定内腔的不透气的柔性膜。 不透气的柔性膜完全包围托盘和医疗容器。 将内腔抽真空至低于大气压的预定真空度。 用于将多个用于在托盘中运输的医疗容器进行包装的方法包括将医疗容器插入托盘，将填充有医疗容器的托盘插入内腔中，将内腔排空到预定的真空压力并将柔性膜密封 预定的真空压力通常保持在内腔中。

公开(公告)号：US5447699A

公开(公告)日：1995-09-05

申请号：US154049

申请日：1993-11-17

申请人： Charles Papciak ,  James Gerhart ,  John Paproski ,  Kathleen A. Parker ,  Paul Norton ,  Robert Nase ,  Bernard Lahendro

发明人： Charles Papciak ,  James Gerhart ,  John Paproski ,  Kathleen A. Parker ,  Paul Norton ,  Robert Nase ,  Bernard Lahendro

IPC分类号： A61L2/26 ,  B01L1/02 ,  B65B55/02 ,  A61L2/20 ,  B65B55/10

CPC分类号： B01L1/02 ,  A61L2/26 ,  B65B55/027

摘要： The present invention relates to a combination container for holding sterilized elements and a sterilizable transfer port for transferring the sterilized elements into an isolation system having a wall. The container includes a flexible bag defining a cavity containing a plurality of the sterilized elements. The container also includes a collar which has an interior surface defining a bore extending through the collar. The bag is secured to the collar with the opening in registry with the bore. A removable seal is movable between a first position where the seal initially extends across the bore to prevent elements from being removed from the cavity and to maintain the sterility of the elements and a second position where the seal is moved from the first position to access the cavity such that the elements are removable from the cavity through the opening and the bore. A transfer port extends through the wall of the isolation system and includes a first end, a second end and a conduit extending between the first and second ends. The collar is in releasable complementary, sealed engagement with the transfer port. A first door is movable between a first position closing the first end of the transfer port to prevent the elements from being moved into the isolation system and support against pressure from a treatment medium and a second position opening the first end of the transfer port to allow the elements to be moved into the isolation system or clean sterile area.

摘要翻译： 本发明涉及一种用于容纳灭菌元件的组合容器和用于将灭菌的元件转移到具有壁的隔离系统中的可杀菌转移口。 容器包括限定包含多个灭菌元件的空腔的柔性袋。 容器还包括具有限定延伸穿过套环的孔的内表面的套环。 袋子被固定到套环上，开口与孔对准。 可拆卸的密封件可以在第一位置和第二位置之间移动，其中密封件首先延伸穿过孔，以防止元件从腔体移除并且保持元件的无菌性，以及第二位置，其中密封件从第一位置移动到接近 空腔使得元件可通过开口和孔从空腔移除。 传送端口延伸穿过隔离系统的壁并且包括在第一端和第二端之间延伸的第一端，第二端和导管。 套环与输送口具有可释放的互补，密封接合。 第一门可在关闭传送端口的第一端的第一位置之间移动，以防止元件移动到隔离系统中，并抵抗来自处理介质的压力和第二位置，打开传送端口的第一端以允许 要移入隔离系统的元素或清洁的无菌区域。

公开(公告)号：US20070208296A1

公开(公告)日：2007-09-06

申请号：US11747773

申请日：2007-05-11

申请人： John Paproski ,  Paul Norton

发明人： John Paproski ,  Paul Norton

IPC分类号： A61M37/00 ,  A61M5/00

CPC分类号： A61J1/2096 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2017 ,  A61J1/2051 ,  A61J1/2055 ,  A61J1/2075 ,  A61J1/2082 ,  A61J1/2086 ,  A61M2005/3104

摘要： A tip cap for a syringe that limits contact between the syringe and a needle tip, wherein the needle tip penetrates the tip cap to one of dispense medication out of the syringe and draw medication into of the syringe. The syringe includes a luer cone extending from a barrel of the syringe. The tip cap includes a penetration wall and a generally cylindrical sleeve extending generally perpendicularly from the penetration wall adjacent a periphery of the penetration wall. The cylindrical sleeve includes a radially, inwardly extending locating shoulder on an inner surface that is positioned a predetermined distance from the penetration wall. The locating shoulder engages an end of the luer cone in an operating position. The penetration wall, cylindrical sleeve and luer cone define a receiving space within which the needle tip is positionable.

摘要翻译： 用于注射器的尖端帽，其限制注射器与针尖之间的接触，其中针尖将尖端帽穿过注射器中的一种分配药物并将药物吸入注射器。 注射器包括从注射器的枪管延伸的鲁尔锥体。 尖端帽包括穿透壁和大体上圆柱形的套筒，该套筒大致垂直于邻近穿透壁周边的穿透壁延伸。 圆柱形套筒包括位于距离穿透壁预定距离的内表面上的径向向内延伸的定位肩部。 定位肩部在操作位置处接合鲁尔锥体的端部。 穿透壁，圆柱形套筒和鲁尔锥体限定了针尖位于其内的容纳空间。

公开(公告)号：US20090093793A1

公开(公告)日：2009-04-09

申请号：US12244688

申请日：2008-10-02

申请人： Yossi Gross ,  Oz Cabiri ,  John Paproski ,  Moshe Barkan

发明人： Yossi Gross ,  Oz Cabiri ,  John Paproski ,  Moshe Barkan

IPC分类号： A61M5/31 ,  A61M5/315

CPC分类号： A61M5/31596 ,  A61M5/1413 ,  A61M5/14248 ,  A61M5/1452 ,  A61M5/1456 ,  A61M5/14566 ,  A61M5/158 ,  A61M5/16827 ,  A61M5/172 ,  A61M5/1723 ,  A61M5/3146 ,  A61M2005/14252 ,  A61M2005/1426 ,  A61M2005/14268 ,  A61M2005/14533 ,  A61M2005/31518 ,  A61M2205/3523 ,  A61M2205/3569 ,  F16H25/12 ,  Y10T74/18576

摘要： Apparatus is described for administering a substance to a subject. A vial contains the substance, an inner surface of the vial being shaped to define a protrusion therefrom. A stopper within the vial is slidably coupled to the vial. A first threaded element is (a) rotatable and (b) substantially immobile proximally with respect to the vial during rotation of the first threaded element. A second threaded element is threadedly coupled to the first threaded element. The protrusion impedes rotation of the second threaded element with respect to the vial. The distal end of the second threaded element remains proximal to a distal end of the stopper during rotation of the first threaded element. The first threaded element, by rotating, linearly advances the stopper and the second threaded element toward a distal end of the vial. Other embodiments are also described.

摘要翻译： 描述了用于向受试者施用物质的装置。 小瓶包含物质，小瓶的内表面成形为从其中限定突起。 小瓶内的塞子可滑动地联接到小瓶。 第一螺纹元件是（a）可旋转并且（b）在第一螺纹元件旋转期间相对于小瓶在近侧基本上不可移动。 第二螺纹元件螺纹连接到第一螺纹元件。 突起阻止第二螺纹元件相对于小瓶的旋转。 第二螺纹元件的远端在第一螺纹元件旋转期间保持靠近止动件的远端。 第一螺纹元件通过旋转线性地使塞子和第二螺纹元件朝向小瓶的远端前进。 还描述了其它实施例。

公开(公告)号：US20060184103A1

公开(公告)日：2006-08-17

申请号：US11059729

申请日：2005-02-17

申请人： John Paproski ,  Paul Norton

发明人： John Paproski ,  Paul Norton

IPC分类号： A61M37/00 ,  A61B19/00 ,  A61M5/32

CPC分类号： A61J1/2096 ,  A61J1/201 ,  A61J1/2013 ,  A61J1/2017 ,  A61J1/2051 ,  A61J1/2055 ,  A61J1/2075 ,  A61J1/2082 ,  A61J1/2086 ,  A61M2005/3104

摘要： A syringe safety device configured to form a fluid coupling between a sealed vial and a syringe having a barrel for receiving fluid and a luer cone extending from the barrel for dispensing the fluid therethrough. The luer cone has a distal end with a syringe orifice therethrough. A connector includes a vial end and a syringe end. The syringe is removably mountable to the syringe end and the vial is mountable to the vial end. A tip cap is removably mounted to the luer cone of the syringe. The tip cap and the distal end define an open receiving space therebetween. A needle is removably mounted to the connector. The needle includes a needle tip facing toward the syringe in an assembled configuration. The needle tip is positioned in the receiving space when the connector and syringe are positioned in an engaged position.

摘要翻译： 一种注射器安全装置，其构造成在密封小瓶和具有用于接收流体的筒体的注射器之间形成流体联接件，以及从所述筒体延伸以分配流体的鲁尔锥体。 鲁尔锥具有远端，注射器孔穿过其中。 连接器包括小瓶端和注射器端。 注射器可拆卸地安装到注射器端，并且小瓶可安装到小瓶端。 尖端帽可拆卸地安装到注射器的鲁尔锥体上。 尖端帽和远端在其间限定开放的容纳空间。 针可拆卸地安装到连接器。 该针包括在组装构型中朝向注射器的针尖。 当连接器和注射器位于接合位置时，针尖定位在容纳空间中。

公开(公告)号：US20080249477A1

公开(公告)日：2008-10-09

申请号：US12062264

申请日：2008-04-03

申请人： John Paproski ,  Paul Norton

发明人： John Paproski ,  Paul Norton

IPC分类号： A61M5/32

CPC分类号： A61M5/326 ,  A61M5/24 ,  A61M5/3271 ,  A61M2005/3267 ,  A61M2005/3268

摘要： A pen injector includes a vial cartridge and a generally tubular body that surrounds the vial cartridge. A needle shield assembly is removably mounted to a mounting end of the body and includes a hollow needle that has a tip for injecting into a patient. A needle hub at least partially surrounds the hollow needle and a slideable sleeve is slideably mounted on the needle hub. The needle hub has an outer surface which deflects the slideable sleeve as the slideable sleeve slides toward a receiving end of the needle hub and into a retracted position. The slideable sleeve bears resiliently on the outer surface of the needle hub during sliding movement of the slideable sleeve relative to the needle hub toward the retracted position such that a restoring force is generated for urging the slideable sleeve to move toward an injection end of the needle hub and into an extended position in which the tip of the needle is located completely inside of the slideable sleeve.

摘要翻译： 笔注射器包括小瓶盒和围绕小瓶盒的大致管状体。 针罩组件可拆卸地安装到主体的安装端，并且包括具有用于注射到患者体内的尖端的中空针头。 针座至少部分地围绕中空针，并且可滑动套筒可滑动地安装在针座上。 针座具有外表面，当可滑动套筒朝着针座的接收端滑动并进入缩回位置时，可滑动套筒偏转。 在可滑动套筒相对于针座朝向缩回位置的滑动运动期间，可滑动套筒弹性地承载在针座的外表面上，使得产生恢复力以促使可滑动套筒向针的注射端移动 并且进入延伸位置，其中针的尖端完全位于可滑动套筒的内部。

公开(公告)号：US20080183140A1

公开(公告)日：2008-07-31

申请号：US11947509

申请日：2007-11-29

申请人： John Paproski ,  Paul Norton

发明人： John Paproski ,  Paul Norton

IPC分类号： A61M5/24 ,  B65D85/00 ,  A61M5/50

CPC分类号： A61M5/002 ,  A61M5/008 ,  A61M5/288 ,  A61M5/3202 ,  A61M5/326 ,  A61M5/3272 ,  A61M5/344 ,  A61M5/348 ,  A61M2005/3247 ,  A61M2005/3267 ,  A61M2005/3268

摘要： The present embodiments provide for a syringe cartridge system that can be used in combination with multiple couplings and injection systems. The syringe cartridge system can be provided in a vacuum packaging assembly configuration. Alternatively, the syringe cartridge system can be provided with a coupler attached to a safety device, a hypodermic needle, or a Luer adaptor. The syringe cartridge system can also be used in combination with an automatic injector.

摘要翻译： 本实施例提供了可以与多个联接器和注射系统组合使用的注射器药筒系统。 注射器盒系统可以设置在真空包装组件配置中。 或者，注射器盒系统可以设置有连接到安全装置，皮下注射针或Luer适配器的联接器。 注射器药筒系统也可以与自动注射器组合使用。