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公开(公告)号：US06754008B1
公开(公告)日：2004-06-22
申请号：US09955005
申请日：2001-09-17
IPC分类号： G02B1502
摘要： Disclosed is an improved lens system for low light applications. This improved low light lens system is designed for any suitable low light application, such as the above described biological imaging application. In one embodiment, a finite conjugate lens system is disclosed. The lens system includes, in order from a camera side to an object side, a first lens group and a second lens group. The first and second lens groups are adapted so that when light is passed from the object side to the image side, a substantially sized region of collimated light is formed between the first and second lens group. Preferably, the first and second lens groups are adapted to demagnify an object at the object side.
摘要翻译： 公开了一种用于低光应用的改进的透镜系统。 这种改进的低光透镜系统被设计用于任何合适的低光应用，例如上述生物成像应用。 在一个实施例中，公开了一种有限共轭透镜系统。 透镜系统从照相机侧到物体侧依次包括第一透镜组和第二透镜组。 第一透镜组和第二透镜组被适配成使得当光从物体侧传送到像侧时，在第一和第二透镜组之间形成基本尺寸的准直光的区域。 优选地，第一透镜组和第二透镜组适于在物体侧使物体缩小。
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公开(公告)号：US09008758B2
公开(公告)日：2015-04-14
申请号：US12978270
申请日：2010-12-23
申请人： Michael D. Cable , Bradley W. Rice , David Nilson
发明人： Michael D. Cable , Bradley W. Rice , David Nilson
IPC分类号： A61B5/05 , G01N21/76 , A61B5/00 , A61B6/03 , A61B6/00 , A61B8/00 , G01N21/64 , G01T1/16 , G01T1/164 , G01T1/29 , A61B8/13 , G01N35/00
CPC分类号： G01N21/76 , A61B5/0035 , A61B5/0059 , A61B5/0077 , A61B6/032 , A61B6/037 , A61B6/4417 , A61B6/5247 , A61B8/13 , A61B8/4416 , G01N21/6456 , G01N35/0099 , G01T1/1603 , G01T1/1648 , G01T1/2985
摘要： The invention described herein provides systems and methods for multi-modal imaging with light and a second form of imaging. Light imaging involves the capture of low intensity light from a light-emitting object. A camera obtains a two-dimensional spatial distribution of the light emitted from the surface of the subject. Software operated by a computer in communication with the camera may then convert two-dimensional spatial distribution data from one or more images into a three-dimensional spatial representation. The second imaging mode may include any imaging technique that compliments light imaging. Examples include magnetic resonance imaging (MRI) and computer topography (CT). An object handling system moves the object to be imaged between the light imaging system and the second imaging system, and is configured to interface with each system.
摘要翻译： 本文描述的本发明提供了用于具有光和第二形式的成像的多模式成像的系统和方法。 光成像涉及捕获来自发光物体的低强度光。 相机获得从被摄体的表面发射的光的二维空间分布。 由与摄像机通信的计算机操作的软件然后可以将二维空间分布数据从一个或多个图像转换为三维空间表示。 第二成像模式可以包括补充光成像的任何成像技术。 实例包括磁共振成像（MRI）和计算机地形（CT）。 物体处理系统将要成像的对象移动到光成像系统和第二成像系统之间，并且被配置为与每个系统接口。
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公开(公告)号：US20110092813A1
公开(公告)日：2011-04-21
申请号：US12978270
申请日：2010-12-23
申请人： Michael D. Cable , Bradley W. Rice , David Nilson
发明人： Michael D. Cable , Bradley W. Rice , David Nilson
IPC分类号： A61B5/05
CPC分类号： G01N21/76 , A61B5/0035 , A61B5/0059 , A61B5/0077 , A61B6/032 , A61B6/037 , A61B6/4417 , A61B6/5247 , A61B8/13 , A61B8/4416 , G01N21/6456 , G01N35/0099 , G01T1/1603 , G01T1/1648 , G01T1/2985
摘要： The invention described herein provides systems and methods for multi-modal imaging with light and a second form of imaging. Light imaging involves the capture of low intensity light from a light-emitting object. A camera obtains a two-dimensional spatial distribution of the light emitted from the surface of the subject. Software operated by a computer in communication with the camera may then convert two-dimensional spatial distribution data from one or more images into a three-dimensional spatial representation. The second imaging mode may include any imaging technique that compliments light imaging. Examples include magnetic resonance imaging (MRI) and computer topography (CT). An object handling system moves the object to be imaged between the light imaging system and the second imaging system, and is configured to interface with each system.
摘要翻译： 本文描述的本发明提供了用于具有光和第二形式的成像的多模式成像的系统和方法。 光成像涉及捕获来自发光物体的低强度光。 相机获得从被摄体的表面发射的光的二维空间分布。 由与摄像机通信的计算机操作的软件然后可以将二维空间分布数据从一个或多个图像转换为三维空间表示。 第二成像模式可以包括补充光成像的任何成像技术。 实例包括磁共振成像（MRI）和计算机地形（CT）。 物体处理系统将要成像的对象移动到光成像系统和第二成像系统之间，并且被配置为与每个系统接口。
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公开(公告)号：US08279334B2
公开(公告)日：2012-10-02
申请号：US11871062
申请日：2007-10-11
申请人： David Nilson , Michael D. Cable , Bradley W. Rice , Kevin Kearney
发明人： David Nilson , Michael D. Cable , Bradley W. Rice , Kevin Kearney
CPC分类号： G01B11/2513 , A61B5/0059 , A61B5/0064 , A61B5/107 , A61B5/6888 , A61B2503/40 , G01B11/2518 , G01N21/6456 , G01N21/763 , G06T7/521 , H04N13/254
摘要： The present invention integrates a structured light source into an imaging system for reconstructing surface topography of an object being imaged. The structured light source includes a mechanism for transmitting a set of lines onto the object from an angle. The lines are displaced, or phase shifted relative to a stage, when they encounter an object with finite height, such as a mouse. This phase shift provides structured light information for the object. A camera captures the structured light information. Using software that employs a structured light analysis, surface topography data for the object is determined from the phase shift of the lines.
摘要翻译： 本发明将结构化光源集成到成像系统中，用于重建被成像物体的表面形貌。 结构化光源包括用于从一角度将一组线传送到物体上的机构。 当它们遇到具有有限高度的对象（例如鼠标）时，线相对于舞台移位或相移。 该相移提供了对象的结构光信息。 相机拍摄结构光信息。 使用采用结构光分析的软件，根据线的相移确定物体的表面形貌数据。
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公开(公告)号：US07589786B2
公开(公告)日：2009-09-15
申请号：US11486239
申请日：2006-07-12
申请人： David Nilson , Michael D. Cable , Bradley W. Rice
发明人： David Nilson , Michael D. Cable , Bradley W. Rice
CPC分类号： G01N21/6456 , A61B5/0059 , A61B2503/40 , G01N21/763
摘要： Systems and methods are provided for taking images of a sample. The sample is placed in an imaging box comprising a moveable stage that allows images of the sample to be taken from various positions and angles within the imaging box. The images are taken by a camera and sent to a processor. Structured light images obtained from one or more views within the imaging box may be used to build a structured light representations of the sample.
摘要翻译： 提供了用于拍摄样本图像的系统和方法。 将样品放置在包括可移动台的成像盒中，该移动台允许从成像盒内的各种位置和角度拍摄样品的图像。 图像由相机拍摄并发送到处理器。 可以使用从成像盒内的一个或多个视图获得的结构化光图像来构建样品的结构光表示。
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公开(公告)号：US07881773B2
公开(公告)日：2011-02-01
申请号：US11485920
申请日：2006-07-12
申请人： Michael D. Cable , Bradley W. Rice , David Nilson
发明人： Michael D. Cable , Bradley W. Rice , David Nilson
IPC分类号： A61B5/00
CPC分类号： G01N21/76 , A61B5/0035 , A61B5/0059 , A61B5/0077 , A61B6/032 , A61B6/037 , A61B6/4417 , A61B6/5247 , A61B8/13 , A61B8/4416 , G01N21/6456 , G01N35/0099 , G01T1/1603 , G01T1/1648 , G01T1/2985
摘要： The invention described herein provides systems and methods for multi-modal imaging with light and a second form of imaging. Light imaging involves the capture of low intensity light from a light-emitting object. A camera obtains a two-dimensional spatial distribution of the light emitted from the surface of the subject. Software operated by a computer in communication with the camera may then convert two-dimensional spatial distribution data from one or more images into a three-dimensional spatial representation. The second imaging mode may include any imaging technique that compliments light imaging. Examples include magnetic resonance imaging (MRI) and computer topography (CT). An object handling system moves the object to be imaged between the light imaging system and the second imaging system, and is configured to interface with each system.
摘要翻译： 本文描述的本发明提供了用于具有光和第二形式的成像的多模式成像的系统和方法。 光成像涉及捕获来自发光物体的低强度光。 相机获得从被摄体的表面发射的光的二维空间分布。 由与摄像机通信的计算机操作的软件然后可以将二维空间分布数据从一个或多个图像转换为三维空间表示。 第二成像模式可以包括补充光成像的任何成像技术。 实例包括磁共振成像（MRI）和计算机地形（CT）。 物体处理系统将要成像的对象移动到光成像系统和第二成像系统之间，并且被配置为与每个系统接口。
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公开(公告)号：US07190991B2
公开(公告)日：2007-03-13
申请号：US10881707
申请日：2004-06-29
申请人： Michael D. Cable , Bradley W. Rice , David Nilson
发明人： Michael D. Cable , Bradley W. Rice , David Nilson
IPC分类号： A61B5/05
CPC分类号： G01N21/76 , A61B5/0035 , A61B5/0059 , A61B5/0077 , A61B6/032 , A61B6/037 , A61B6/4417 , A61B6/5247 , A61B8/13 , A61B8/4416 , G01N21/6456 , G01N35/0099 , G01T1/1603 , G01T1/1648 , G01T1/2985
摘要： The invention described herein provides systems and methods for multi-modal imaging with light and a second form of imaging. Light imaging involves the capture of low intensity light from a light-emitting object. A camera obtains a two-dimensional spatial distribution of the light emitted from the surface of the subject. Software operated by a computer in communication with the camera may then convert two-dimensional spatial distribution data from one or more images into a three-dimensional spatial representation. The second imaging mode may include any imaging technique that compliments light imaging. Examples include magnetic resonance imaging (MRI) and computer topography (CT). An object handling system moves the object to be imaged between the light imaging system and the second imaging system, and is configured to interface with each system.
摘要翻译： 本文描述的本发明提供了用于具有光和第二形式的成像的多模式成像的系统和方法。 光成像涉及捕获来自发光物体的低强度光。 相机获得从被摄体的表面发射的光的二维空间分布。 由与摄像机通信的计算机操作的软件然后可以将二维空间分布数据从一个或多个图像转换为三维空间表示。 第二成像模式可以包括补充光成像的任何成像技术。 实例包括磁共振成像（MRI）和计算机地形（CT）。 物体处理系统将要成像的对象移动到光成像系统和第二成像系统之间，并且被配置为与每个系统接口。
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公开(公告)号：US07298415B2
公开(公告)日：2007-11-20
申请号：US11127842
申请日：2005-05-11
申请人： David Nilson , Michael D. Cable , Bradley W. Rice , Kevin Kearney
发明人： David Nilson , Michael D. Cable , Bradley W. Rice , Kevin Kearney
CPC分类号： G01B11/2513 , A61B5/0059 , A61B5/0064 , A61B5/107 , A61B5/6888 , A61B2503/40 , G01B11/2518 , G01N21/6456 , G01N21/763 , G06T7/521 , H04N13/254
摘要： The present invention integrates a structured light source into an imaging system for reconstructing surface topography of an object being imaged. The structured light source includes a mechanism for transmitting a set of lines onto the object from an angle. The lines are displaced, or phase shifted relative to a stage, when they encounter an object with finite height, such as a mouse. This phase shift provides structured light information for the object. A camera captures the structured light information. Using software that employs a structured light analysis, surface topography data for the object is determined from the phase shift of the lines.
摘要翻译： 本发明将结构化光源集成到成像系统中，用于重建被成像物体的表面形貌。 结构化光源包括用于从一角度将一组线传送到物体上的机构。 当它们遇到具有有限高度的对象（例如鼠标）时，线相对于舞台移位或相移。 该相移提供了对象的结构光信息。 相机拍摄结构光信息。 使用采用结构光分析的软件，根据线的相移确定物体的表面形貌数据。
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公开(公告)号：US07813782B2
公开(公告)日：2010-10-12
申请号：US11485923
申请日：2006-07-12
申请人： Michael D. Cable , Bradley W. Rice , David Nilson
发明人： Michael D. Cable , Bradley W. Rice , David Nilson
IPC分类号： A61B5/00
CPC分类号： G01N21/76 , A61B5/0035 , A61B5/0059 , A61B5/0077 , A61B6/032 , A61B6/037 , A61B6/4417 , A61B6/5247 , A61B8/13 , A61B8/4416 , G01N21/6456 , G01N35/0099 , G01T1/1603 , G01T1/1648 , G01T1/2985
摘要： The invention described herein provides systems and methods for handling objects within an imaging system, such as a multi-modal imaging system. An object handling system operates to position an object to be imaged in an interior cavity of a light imaging system, and also moves the object to be imaged between the light imaging system and a second imaging system. The object handling system can include components such as a stage that supports the object, a manipulator configured to move the stage between the interior and exterior of the light imaging system and a light seal configured to interface with a light seal on an exterior wall of the light imaging system.
摘要翻译： 本文描述的本发明提供了用于处理诸如多模式成像系统的成像系统内的物体的系统和方法。 物体处理系统用于将要成像的物体定位在光成像系统的内部空腔中，并且还使待成像对象在光成像系统和第二成像系统之间移动。 物体处理系统可以包括诸如支撑物体的台架的部件，被配置为在光成像系统的内部和外部之间移动台架的机械手以及配置成与所述光成像系统的外壁上的光密封相接合的光密封件 光成像系统。
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公开(公告)号：US07595838B2
公开(公告)日：2009-09-29
申请号：US11485721
申请日：2006-07-12
申请人： David Nilson , Michael D. Cable , Bradley W. Rice
发明人： David Nilson , Michael D. Cable , Bradley W. Rice
IPC分类号： H04N5/225
CPC分类号： G01N21/6456 , A61B5/0059 , A61B2503/40 , G01N21/763
摘要： Systems and methods are provided for taking images of a sample. The sample is placed in an imaging box comprising a moveable stage that allows images of the sample to be taken from various positions and angles within the imaging box. The images are taken by a camera and sent to a processor. Structured light images obtained from one or more views within the imaging box may be used to build a structured light representations of the sample.
摘要翻译： 提供了用于拍摄样本图像的系统和方法。 将样品放置在包括可移动台的成像盒中，该移动台允许从成像盒内的各种位置和角度拍摄样品的图像。 图像由相机拍摄并发送到处理器。 可以使用从成像盒内的一个或多个视图获得的结构化光图像来构建样品的结构光表示。
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