公开(公告)号：US09358350B2

公开(公告)日：2016-06-07

申请号：US13568033

申请日：2012-08-06

申请人： Mahalaxmi Gita Bangera ,  Edward S. Boyden ,  Hon Wah Chin ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Robert Langer ,  Eric C. Leuthardt ,  Stephen L. Malaska ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Sharon L. Wolda ,  Lowell L. Wood, Jr.

发明人： Mahalaxmi Gita Bangera ,  Edward S. Boyden ,  Hon Wah Chin ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Robert Langer ,  Eric C. Leuthardt ,  Stephen L. Malaska ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Sharon L. Wolda ,  Lowell L. Wood, Jr.

IPC分类号： G06F19/00 ,  A61M5/00 ,  A61M31/00 ,  A61M5/42 ,  A61M5/46 ,  A61B17/34 ,  G06F17/50 ,  A61B19/00

CPC分类号： A61B34/10 ,  A61B17/3403 ,  A61B2017/3411 ,  A61B2034/108 ,  A61B2090/363 ,  A61M5/422 ,  A61M5/427 ,  A61M5/46 ,  A61M2205/13 ,  A61M2207/00 ,  A61M2210/0606 ,  B29C64/386 ,  B33Y50/02 ,  B33Y80/00 ,  G05B19/4099 ,  G05B2219/35134 ,  G05B2219/49007 ,  G06F17/5086

摘要： Systems and methods for wearable injection guides are described, which include: acquiring one or more digital images of a body region of an individual with at least one image capture device; creating a digitally rendered model of a wearable injection guide from the one or more digital images of the body region of the individual; adding one or more digitally rendered fiducials indicative of at least one treatment parameter to the digitally rendered model of the wearable injection guide; and forming the wearable injection guide from the digitally rendered model of the wearable injection guide, the formed wearable injection guide including one or more fiducials corresponding to the one or more digitally rendered fiducials on the digitally rendered model of the wearable injection guide.

摘要翻译： 描述了可穿戴式注射引导件的系统和方法，其包括：用至少一个图像捕获装置获取个体的身体区域的一个或多个数字图像; 从个体的身体区域的一个或多个数字图像创建可戴式注射引导件的数字渲染模型; 将指示至少一个治疗参数的一个或多个数字呈现的基准添加到所述可佩戴注射引导件的数字渲染模型; 以及从所述可穿戴式注射导向器的数字渲染模型形成所述可穿戴式注射导向器，所述可穿戴式注射引导件包括与所述可穿戴式注射导向器的数字渲染模型上的所述一个或多个数字呈现的基准相对应的一个或多个基准。

公开(公告)号：US20140039451A1

公开(公告)日：2014-02-06

申请号：US13567921

申请日：2012-08-06

申请人： Mahalaxmi Gita Bangera ,  Edward S. Boyden ,  Hon Wah Chin ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Robert Langer ,  Eric C. Leuthardt ,  Stephen L. Malaska ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Sharon L. Wolda ,  Lowell L. Wood, JR.

发明人： Mahalaxmi Gita Bangera ,  Edward S. Boyden ,  Hon Wah Chin ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Jordin T. Kare ,  Robert Langer ,  Eric C. Leuthardt ,  Stephen L. Malaska ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene ,  Sharon L. Wolda ,  Lowell L. Wood, JR.

IPC分类号： A61M5/42

CPC分类号： A61B34/10 ,  A61B17/3403 ,  A61B2017/3411 ,  A61B2034/108 ,  A61B2090/363 ,  A61M5/422 ,  A61M5/427 ,  A61M5/46 ,  A61M2205/13 ,  A61M2207/00 ,  A61M2210/0606 ,  B29C64/386 ,  B33Y50/02 ,  B33Y80/00 ,  G05B19/4099 ,  G05B2219/35134 ,  G05B2219/49007 ,  G06F17/5086

摘要： Wearable injection guides and manufacture and use thereof are described, which include: a rigid material formed to substantially conform in shape to a topography of a body region of an individual, the rigid material substantially impenetrable to an injection needle, and the rigid material including one or more injection needle access regions arranged in a treatment pattern.

摘要翻译： 描述了可穿戴的注射引导件及其制造和使用，其包括：刚性材料，形成为基本上符合个体的身体区域的形状，基本上不能穿透到注射针的刚性材料，并且刚性材料包括一个 或更多的注射针入口区域以治疗图案排列。

公开(公告)号：US09144489B2

公开(公告)日：2015-09-29

申请号：US13495275

申请日：2012-06-13

申请人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61F2/12 ,  A61B5/07 ,  A61B5/145 ,  A61B5/1473

CPC分类号： A61F2/12 ,  A61B5/076 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/14735

摘要： Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; at least one fluid-permeable cover, the cover completely enveloping the shell; a plurality of sensor modules attached to the shell, the sensor modules oriented to detect one or more analytes in a fluid between the shell and the cover, the sensor modules positioned at a distance from each other, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules.

摘要翻译： 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 至少一个流体可透过的盖，所述盖完全包围所述壳; 多个传感器模块，其附接到所述壳体，所述传感器模块定向成检测所述壳体和所述盖子之间的流体中的一种或多种分析物，所述传感器模块彼此间隔一定距离，其中所述多个传感器模块中的每一个包括 唯一标识符; 以及可操作地附接到所述多个传感器模块的至少一个电源。

公开(公告)号：US20130338773A1

公开(公告)日：2013-12-19

申请号：US13495310

申请日：2012-06-13

申请人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61F2/12

CPC分类号： A61F2/12 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14546 ,  A61B5/14735 ,  A61B5/4312 ,  A61B5/686 ,  A61B5/6867 ,  A61B2562/046 ,  A61F2250/0001 ,  A61F2250/0002

摘要： Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.

摘要翻译： 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 从所述壳体的外表面延伸的多个突起，所述突起形成与所述壳体的外表面相邻的多个隔室; 至少一个液体可渗透的盖附接到突起，所述盖完全包围壳体和多个突起; 以及多个传感器模块，其附接到壳体并且彼此间隔一定距离，每个传感器模块被定向成检测多个隔室中的一个内的流体中的一种或多种分析物，其中多个传感器模块 包括唯一的标识符并被配置为利用从外部源发送的能量。

公开(公告)号：US20130338772A1

公开(公告)日：2013-12-19

申请号：US13495299

申请日：2012-06-13

申请人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61F2/12

CPC分类号： A61F2/12 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/14503 ,  A61B5/14507 ,  A61B5/14546 ,  A61B5/14735 ,  A61B5/4312 ,  A61B5/686 ,  A61B5/6867 ,  A61B2560/0214 ,  A61B2560/0219 ,  A61B2560/0443 ,  A61B2562/028 ,  A61B2562/06 ,  A61B2562/162 ,  A61B2562/168 ,  G01N33/528 ,  G01N33/57415

摘要： Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; a plurality of sensor modules attached to the shell, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules.

摘要翻译： 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 从所述壳体的外表面延伸的多个突起，所述突起形成与所述壳体的外表面相邻的多个隔室; 至少一个液体可渗透的盖附接到突起，所述盖完全包围壳体和多个突起; 多个传感器模块，其附接到所述壳体，所述传感器模块中的每一个被定向以检测所述多个隔室中的一个内的流体中的一种或多种分析物，其中所述多个传感器模块中的每一个包括唯一标识符; 以及可操作地附接到所述多个传感器模块的至少一个电源。

公开(公告)号：US20130338769A1

公开(公告)日：2013-12-19

申请号：US13495252

申请日：2012-06-13

申请人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61F2/12

CPC分类号： A61F2/12 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/14546 ,  A61B5/4312 ,  A61B5/686 ,  A61B5/6867 ,  A61B2560/0219 ,  A61F2250/0085 ,  A61F2250/0096

摘要： Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the plurality of sensor modules oriented to detect one or more analytes in a fluid adjacent to the shell, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.

公开(公告)号：US09144488B2

公开(公告)日：2015-09-29

申请号：US13495252

申请日：2012-06-13

申请人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61F2/12 ,  A61B5/07 ,  A61B5/00 ,  A61B5/145

CPC分类号： A61F2/12 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/14546 ,  A61B5/4312 ,  A61B5/686 ,  A61B5/6867 ,  A61B2560/0219 ,  A61F2250/0085 ,  A61F2250/0096

摘要： Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the plurality of sensor modules oriented to detect one or more analytes in a fluid adjacent to the shell, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.

摘要翻译： 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 以及多个传感器模块，其附接到壳体并且彼此间隔一定距离，多个传感器模块中的每一个被定向成检测与壳体相邻的流体中的一种或多种分析物，其中多个传感器模块中的每一个包括 唯一的标识符并被配置为利用从外部源发送的能量。

公开(公告)号：US08808373B2

公开(公告)日：2014-08-19

申请号：US13495310

申请日：2012-06-13

申请人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61F2/24

CPC分类号： A61F2/12 ,  A61B5/0031 ,  A61B5/14503 ,  A61B5/1451 ,  A61B5/14546 ,  A61B5/14735 ,  A61B5/4312 ,  A61B5/686 ,  A61B5/6867 ,  A61B2562/046 ,  A61F2250/0001 ,  A61F2250/0002

摘要： Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.

摘要翻译： 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 从所述壳体的外表面延伸的多个突起，所述突起形成与所述壳体的外表面相邻的多个隔室; 至少一个液体可渗透的盖附接到突起，所述盖完全包围壳体和多个突起; 以及多个传感器模块，其附接到壳体并且彼此间隔一定距离，每个传感器模块被定向成检测多个隔室中的一个内的流体中的一种或多种分析物，其中多个传感器模块 包括唯一的标识符并被配置为利用从外部源发送的能量。

公开(公告)号：US08795359B2

公开(公告)日：2014-08-05

申请号：US13495299

申请日：2012-06-13

申请人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61F2/12

CPC分类号： A61F2/12 ,  A61B5/0031 ,  A61B5/076 ,  A61B5/14503 ,  A61B5/14507 ,  A61B5/14546 ,  A61B5/14735 ,  A61B5/4312 ,  A61B5/686 ,  A61B5/6867 ,  A61B2560/0214 ,  A61B2560/0219 ,  A61B2560/0443 ,  A61B2562/028 ,  A61B2562/06 ,  A61B2562/162 ,  A61B2562/168 ,  G01N33/528 ,  G01N33/57415

摘要： Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; a plurality of projections extending from an external surface of the shell, the projections forming a plurality of compartments adjacent to the external surface of the shell; at least one fluid-permeable cover attached to the projections, the cover completely enveloping the shell and the plurality of projections; a plurality of sensor modules attached to the shell, each of the sensor modules oriented to detect one or more analytes in a fluid within one of the plurality of compartments, wherein each of the plurality of sensor modules includes a unique identifier; and at least one power source operably attached to the plurality of sensor modules.

摘要翻译： 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 从所述壳体的外表面延伸的多个突起，所述突起形成与所述壳体的外表面相邻的多个隔室; 至少一个液体可渗透的盖附接到突起，所述盖完全包围壳体和多个突起; 多个传感器模块，其附接到所述壳体，所述传感器模块中的每一个被定向以检测所述多个隔室中的一个内的流体中的一种或多种分析物，其中所述多个传感器模块中的每一个包括唯一标识符; 以及可操作地附接到所述多个传感器模块的至少一个电源。

公开(公告)号：US20130338771A1

公开(公告)日：2013-12-19

申请号：US13495288

申请日：2012-06-13

申请人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

发明人： Edward S. Boyden ,  Gregory J. Della Rocca ,  Paul Duesterhoft ,  Daniel Hawkins ,  Roderick A. Hyde ,  Robert Langer ,  Eric C. Leuthardt ,  Terence Myckatyn ,  Parag Jitendra Parikh ,  Dennis J. Rivet ,  Joshua S. Shimony ,  Michael A. Smith ,  Elizabeth A. Sweeney ,  Clarence T. Tegreene

IPC分类号： A61F2/12

CPC分类号： A61B5/686 ,  A61B5/076 ,  A61B5/4312 ,  A61B5/4848 ,  A61B5/4851 ,  A61F2/12

摘要： Breast implants including sensor modules and related methods are described herein. Breast implants include those with: a shell configured to be substantially filled with a viscous material; at least one fluid-permeable cover, the cover completely enveloping the shell; and a plurality of sensor modules attached to the shell and positioned at a distance from each other, each of the sensor modules oriented to detect one or more analytes in a fluid between the shell and the cover, wherein each of the plurality of sensor modules includes a unique identifier and is configured to utilize energy transmitted from an external source.

摘要翻译： 本文描述了包括传感器模块和相关方法的乳房植入物。 乳房植入物包括具有：壳体被构造为基本上被粘性材料填充的植入物; 至少一个流体可透过的盖，所述盖完全包围所述壳; 以及多个传感器模块，其附接到壳体并且彼此间隔一定距离，每个传感器模块被定向成检测壳体和盖子之间的流体中的一种或多种分析物，其中多个传感器模块中的每一个包括 唯一的标识符并被配置为利用从外部源发送的能量。