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公开(公告)号：US12245940B2
公开(公告)日：2025-03-11
申请号：US17521571
申请日：2021-11-08
Applicant: Edwards Lifesciences Corporation
Inventor： David M. Taylor , Tri D. Tran , Sean Chow , David L. Hauser , Pui Tong Ho , Alexander H. Cooper
IPC: A61F2/24
Abstract: Certain aspects of the disclosure concern a device for repairing or replacing a native heart valve. The device can include a frame including a first set of struts intersecting with a second set of struts at a plurality of strut connection points. The frame can be radially expandable from a radially collapsed state to a radially expanded state. The device can include at least one expansion feature including a screw head and a screw shaft connected to the screw head. The screw shaft can extend through a first strut connection point and a second strut connection point. The device can further include a plurality of penetrating members extending from a first end of the frame. Rotating the screw shaft in a first direction can radially expand the frame from the radially collapsed state to the radially expanded state.
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公开(公告)号：US20230346548A1
公开(公告)日：2023-11-02
申请号：US18206213
申请日：2023-06-06
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Netanel Benichou , Stanton J. Rowe , Sean Chow
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2220/0075 , A61F2250/0059
Abstract: Prosthetic heart valves are described. A prosthetic heart valve can include a radially collapsible and expandable frame with a plurality of struts arranged to form a plurality of circumferentially extending rows of closed cells. A prosthetic heart valve can further include a leaflet structure with a plurality of leaflet sections joined to form commissures. The frame includes a plurality of pairs of posts, the posts of each pair spaced apart from each other to define an opening. Each commissure extends radially outwardly through the opening of a respective pair of posts. The pairs of posts have respective lower ends that are axially spaced from a lower end of the frame. An uppermost row of closed cells is formed partly by an uppermost row of circumferentially extending struts interconnecting adjacent posts. A lowermost row of closed cells includes a greater number of closed cells than the uppermost row of closed cells.
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公开(公告)号：US11660188B2
公开(公告)日：2023-05-30
申请号：US17706253
申请日：2022-03-28
Applicant: Edwards Lifesciences Corporation
Inventor： Netanel Benichou , Stanton J. Rowe , Sean Chow
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2220/0075 , A61F2250/0059
Abstract: Prosthetic heart valves are described. Prosthetic heart valves can include radially expandable and compressible inner and outer metal frames. The inner frame can be disposed within a lumen of the outer frame and can be coupled to the outer frame. An outflow end of the inner frame can be coupled to and/or located at an outflow end of the outer frame. An end portion of the inner frame can be spaced radially inwardly from an inner surface of the outer frame, such that a radial gap exists between the inner surface of the outer frame and an outer surface of the inner frame. Prosthetic heart valves can further include a plurality of leaflets disposed within and supported by the inner frame, such as by commissure posts of the inner frame.
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公开(公告)号：US11596515B2
公开(公告)日：2023-03-07
申请号：US17705131
申请日：2022-03-25
Applicant: Edwards Lifesciences Corporation
Inventor： Netanel Benichou , Stanton J. Rowe , Sean Chow
IPC: A61F2/24
Abstract: Prosthetic heart valves are described. Prosthetic heart valves can include radially expandable and compressible inner and outer metal frames. The inner frame can be disposed within a lumen of the outer frame and can be coupled to the outer frame. An outflow end of the inner frame can be coupled to and/or located at an outflow end of the outer frame. An end portion of the inner frame can be spaced radially inwardly from an inner surface of the outer frame, such that a radial gap exists between the inner surface of the outer frame and an outer surface of the inner frame. Prosthetic heart valves can further include a plurality of leaflets disposed within and supported by the inner frame, such as by commissure posts of the inner frame.
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公开(公告)号：US20220061990A1
公开(公告)日：2022-03-03
申请号：US17521571
申请日：2021-11-08
Applicant: Edwards Lifesciences Corporation
Inventor： David M. Taylor , Tri D. Tran , Sean Chow , David L. Hauser , Pui Tong Ho , Alexander H. Cooper
IPC: A61F2/24
Abstract: Certain aspects of the disclosure concern a device for repairing or replacing a native heart valve. The device can include a frame including a first set of struts intersecting with a second set of struts at a plurality of strut connection points. The frame can be radially expandable from a radially collapsed state to a radially expanded state. The device can include at least one expansion feature including a screw head and a screw shaft connected to the screw head. The screw shaft can extend through a first strut connection point and a second strut connection point. The device can further include a plurality of penetrating members extending from a first end of the frame. Rotating the screw shaft in a first direction can radially expand the frame from the radially collapsed state to the radially expanded state.
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Patent Agency Ranking
公开(公告)号：US09901446B2
公开(公告)日：2018-02-27
申请号：US14326062
申请日：2014-07-08
Applicant: Edwards Lifesciences Corporation
Inventor： Netanel Benichou , Stanton J. Rowe , Sean Chow
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2220/0075 , A61F2250/0059
Abstract: Disclosed replacement heart valves can be designed to be delivered to a native valve site while crimped on a delivery catheter. The crimped profile of the replacement valve can be minimized by, for example, separating a frame or stent structure from a leaflet structure, along the axial direction. Disclosed replacement valves can be transitioned from a delivery configuration, in which the crimped profile can be minimized, to an operating configuration. The replacement valve can be fully assembled in both the delivery and operating configurations. In some embodiments, the leaflets can be positioned outside of the stent in the delivery configuration, and positioned inside of the stent lumen in the operating configuration. Disclosed replacement valves can include a flexible sleeve coupling the leaflets to the stent and facilitating the transition to the operating configuration. Methods of implanting said replacement valves are also disclosed.
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公开(公告)号：US20180036124A1
公开(公告)日：2018-02-08
申请号：US15789526
申请日：2017-10-20
Applicant: Edwards Lifesciences Corporation
Inventor： Tri D. Tran , Ronaldo C. Cayabyab , David J. Evans , Sean Chow , Christopher Chia , Tamir S. Levi
CPC classification number: A61F2/2433 , A61F2/958 , A61F2002/485 , A61F2002/9517 , A61F2002/9586 , A61F2250/0003 , A61F2250/0021 , A61M25/1002 , A61M25/10184 , A61M2025/1013 , A61M2025/1084
Abstract: A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion. The shaft is configured such that a fluid can flow through the lumen and the openings. The inner balloon has end portions and a center portion disposed between the end portions. The inner balloon is mounted on the distal end portion of the shaft and is in fluid communication with the openings of the shaft. When the inner balloon is inflated with the fluid, the end portions expand farther radially outwardly than the center portion. The outer balloon is mounted to the shaft and disposed over the inner balloon. The outer balloon is configured to fully expand after the inner balloon at least partially expands.
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公开(公告)号：US20160158497A1
公开(公告)日：2016-06-09
申请号：US14949707
申请日：2015-11-23
Applicant: Edwards Lifesciences Corporation
Inventor： Tri D. Tran , Sean Chow , Ronaldo C. Cayabyab
CPC classification number: A61M25/0147 , A61F2/2427 , A61F2/2436 , A61M25/0071 , A61M25/0136 , A61M2025/0161
Abstract: In one representative embodiment, a steerable catheter device comprises a shaft comprising a proximal portion, a distal portion, and a pull-wire lumen that extends at least partially through the proximal and distal portions. A pull wire extends through the pull-wire lumen and has a proximal end portion and a distal end portion, wherein the distal end portion of pull wire is fixed to the distal end portion of the shaft. An adjustment mechanism is operatively connected to the proximal end portion of the pull wire and configured to increase and decrease tension in the pull wire to adjust the curvature of the distal portion of the shaft. An axially non-compressible pull-wire sleeve extends co-axially through the pull-wire lumen and over the pull wire.
Abstract translation: 在一个代表性的实施例中，可导向的导管装置包括轴，所述轴包括至少部分地延伸通过近端部分和远端部分的近端部分，远侧部分和拉线内腔。 拉线延伸穿过拉线管腔，并且具有近端部分和远端部分，其中拉线的远端部分固定到轴的远端部分。 调节机构可操作地连接到拉线的近端部分并且被配置为增加和减小拉线中的张力以调节轴的远端部分的曲率。 轴向不可压缩的拉线套筒同轴地延伸穿过拉线内腔和拉线。
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公开(公告)号：US12268593B2
公开(公告)日：2025-04-08
申请号：US17334464
申请日：2021-05-28
Applicant: Edwards Lifesciences Corporation
Inventor： Dustin P. Armer , Sean Chow , Jenny Nguyen , Emil Karapetian , Tri D. Tran
IPC: A61F2/24
Abstract: Anchor devices and methods used to secure a prosthetic valve to a native valve annulus are described. The anchor device can be a separate expandable element from the prosthetic valve that is first advanced to the annulus and deployed, after which an expandable prosthetic valve is advanced to within the annulus and deployed. The combination of the two elements can apply a clamping force to the valve leaflets which holds the prosthetic valve in place. The anchor device can have a lower or ventricular portion and an upper or atrial portion. The anchor device can include one or more leaflet clamping portions. One, two, or more upstanding vertical posts between the clamping portions can extend upward at the valve commissures and support the upper portion, which can include one or more structures for leak prevention.
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公开(公告)号：US20240099839A1
公开(公告)日：2024-03-28
申请号：US18536042
申请日：2023-12-11
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor： Tri D. Tran , Ronaldo C. Cayabyab , David J. Evans , Sean Chow , Christopher Chia , Tamir S. Levi
CPC classification number: A61F2/2433 , A61F2/958 , A61M25/10184
Abstract: A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion. The shaft is configured such that a fluid can flow through the lumen and the openings. The inner balloon has end portions and a center portion disposed between the end portions. The inner balloon is mounted on the distal end portion of the shaft and is in fluid communication with the openings of the shaft. When the inner balloon is inflated with the fluid, the end portions expand farther radially outwardly than the center portion. The outer balloon is mounted to the shaft and disposed over the inner balloon. The outer balloon is configured to fully expand after the inner balloon at least partially expands.
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