2,4-Dioxopyrrolidine and 2,4-dioxotetrahydrofan derivatives and medicines containing the same at the active ingredient
    1.
    发明授权
    2,4-Dioxopyrrolidine and 2,4-dioxotetrahydrofan derivatives and medicines containing the same at the active ingredient 有权
    2,4-二氧代吡咯烷和2,4-二氧代四氢呋喃衍生物以及含有该活性成分的药物

    公开(公告)号:US06232335B1

    公开(公告)日:2001-05-15

    申请号:US09254685

    申请日:1999-03-17

    IPC分类号: A61K31496

    CPC分类号: C07D403/10 C07D405/10

    摘要: Compounds including 1-(biphenyl-4-yl)methyl-1H-1,2,4-triazoles and 1-(biphenyl-4-yl)methyl-4H-1,2,4-triazoles each having a (2,4-dioxopyrrolidine-5-ylidene)methyl or (2,4-dioxo-tetrahydrofiuran-5-ylidene)methyl group as the substituent at the 2′-position and salts thereof are lowly toxic and highly safe and are useful as an angiotensin II antagonist. Thus, these compounds can be used in medicines, which contain these compounds as an active ingredient.

    摘要翻译: 包括1-(联苯-4-基)甲基-1H-1,2,4-三唑和1-(联苯-4-基)甲基-4H-1,2,4-三唑的化合物各自具有(2,4 - 二氧代吡咯烷-5-亚基)甲基或(2,4-二氧代 - 四氢呋喃-5-亚基)甲基在2'-位上的取代基及其盐具有低毒性和高度安全性,可用作血管紧张素II拮抗剂 。 因此,这些化合物可以用于含有这些化合物作为活性成分的药物中。

    2,4-dioxopyrrolidine and 2,4-dioxotetrahydrofuran derivatives and medicines containing the same as the active ingredient
    2.
    发明授权
    2,4-dioxopyrrolidine and 2,4-dioxotetrahydrofuran derivatives and medicines containing the same as the active ingredient 有权
    2,4-二氧代四氢呋喃衍生物和含有该活性成分的药物

    公开(公告)号:US06358984B1

    公开(公告)日:2002-03-19

    申请号:US09637613

    申请日:2000-08-11

    IPC分类号: A61K314196

    CPC分类号: C07D403/10 C07D405/10

    摘要: Compounds including 1-(biphenyl-4-yl)methyl-1H-1,2,4-triazoles and 1-(biphenyl-4-yl)methyl-4H-1,2,4-triazoles each having a (2,4-dioxopyrrolidine-5-ylidene) methyl or (2,4-dioxo-tetrahydrofuran-5-ylidene)methyl group as the substituent at the 2′-position and salts thereof are lowly toxic and highly safe and are useful as an angiotensin II antagonist. Thus, these compounds can be used in medicines, which contain these compounds as an active ingredient.

    摘要翻译: 包括1-(联苯-4-基)甲基-1H-1,2,4-三唑和1-(联苯-4-基)甲基-4H-1,2,4-三唑的化合物各自具有(2,4 - 二氧代吡咯烷-5-亚基)甲基或(2,4-二氧代 - 四氢呋喃-5-亚基)甲基作为2位的取代基及其盐具有低毒性和高度安全性,可用作血管紧张素II拮抗剂 。 因此,这些化合物可以用于含有这些化合物作为活性成分的药物中。

    Apparatus and methods for transferring workpiece in a transfer press
machine
    3.
    发明授权
    Apparatus and methods for transferring workpiece in a transfer press machine 有权
    在转印机中转印工件的设备和方法

    公开(公告)号:US6109087A

    公开(公告)日:2000-08-29

    申请号:US300259

    申请日:1999-04-27

    IPC分类号: B21D43/05 B30B13/00

    CPC分类号: B21D43/055

    摘要: Cross bars 18, to which workpiece holders 19 are attached, are provided across a press line L, together with feed beams 14 between which the cross bars are installed and which are suspended from the lift beams 13 and can move freely in the horizontal direction of the press line. A feed and transfer device 52 can move the feed beams freely in the horizontal direction of the press line. A connecting rod 56 connects the feed beams and the rack beam in a freely rotatable manner. A connecting link 60 connects a point in the vicinity of an intermediate portion of the connecting rod to a bracket 58 installed on the rack beam, in a freely rotatable manner. An operating direction changeover mechanism 61 converts the differential movement caused by the curvature of the press transfer motion, produced in the feed beams when the lift beams are raised or lowered, into a horizontal movement in the direction of the press line in synchronism with the raising or lowering of the lift beams.

    摘要翻译: 连接工件保持器19的横杆18与进给梁14一起设置在挤压线L上,进给梁14安装有横杆,并且悬挂在提升梁13上并且可沿水平方向自由移动 新闻线。 进给和传送装置52可以在按压线的水平方向上自由移动进给梁。 连杆56以可自由旋转的方式连接进给梁和齿条梁。 连接连杆60以可自由旋转的方式将连杆的中间部附近的点与安装在齿条梁上的支架58连接。 操作方向切换机构61将提升梁上升或下降时由供给梁产生的压力传递运动的曲率引起的差动运动转换成与升高同步的沿压线方向的水平运动 或降低升降梁。

    Dental plaque collecting tool
    4.
    发明申请
    Dental plaque collecting tool 审中-公开
    牙菌斑收集工具

    公开(公告)号:US20060204927A1

    公开(公告)日:2006-09-14

    申请号:US11334489

    申请日:2006-01-19

    IPC分类号: A61C3/00

    CPC分类号: A61C3/00 A61B10/00

    摘要: A new dental plaque collecting tool comprising a handle part 1, a neck part 2, which has an upper edge with a curved face 2a comprising has a portion positioned on the lower side of an upper edge extending line of a handle part 1, and a continuing portion positioned on the upper side thereof, and a lower edge positioned on the upper side of a lower edge extending line of the handle part 1 and formed with a taper in width and a dental plaque collecting part 3 comprising an upper extending plane 3a having a width of 0.2 to 0.7 mm and an area of 2 to 10 mm2 with an angle θa of 90 to 115 degrees with respect to the handle part 1 at an end of the curved face 2a, an acute tip end, a lower edge face 3b and a convex part 3c.

    摘要翻译: 一种新的牙菌斑收集工具,其包括手柄部分1,颈部部分2,其具有具有弯曲面2a的上边缘,该上部边缘具有位于手柄部分1的上边缘延伸线的下侧的部分,以及 位于其上侧的连续部分和位于手柄部分1的下边缘延伸线的上侧的下边缘,并且形成有宽度的锥形,以及牙斑收集部分3,其包括上延伸平面3 a具有0.2至0.7mm的宽度和2至10mm 2的面积,在曲面2a的端部处的角度θa相对于把手部分1的角度θa为90至115度 尖锐尖端,下边缘面3b和凸部3c。

    Composition for caries prevention
    5.
    发明申请
    Composition for caries prevention 审中-公开
    防止龋齿的成分

    公开(公告)号:US20050089481A1

    公开(公告)日:2005-04-28

    申请号:US10957829

    申请日:2004-10-05

    摘要: To obtain a composition for caries prevention, which has effects for efficiently suppressing demineralization and promoting remineralization and stability in keeping for a long time, 0.01 to 10% by weight of sodium carboxymethylcellulose having the etherification degree of 0.7 to 1.0 is used in a composition blended with a casein phosphopeptide-amorphous calcium phosphate complex (CPP-ACP) and/or a casein phosphopeptide-amorphous calcium fluoride phosphate complex (CPP-ACFP), a sodium carboxymethylcellulose, a viscosity regulator and water.

    摘要翻译: 为了获得防止龋齿的组合物,其具有有效抑制软化并促进再矿化和长时间保持稳定性的作用,在混合组合物中使用0.01〜10重量%的醚化度为0.7〜1.0的羧甲基纤维素钠 与酪蛋白磷酸肽 - 无定形磷酸钙复合物(CPP-ACP)和/或酪蛋白磷酸肽 - 无定形磷酸氟化钙复合物(CPP-ACFP),羧甲基纤维素钠,粘度调节剂和水。

    Tooth surface treatment material and tooth surface treatment method
    6.
    发明授权
    Tooth surface treatment material and tooth surface treatment method 失效
    牙齿表面处理材料和牙齿表面处理方法

    公开(公告)号:US06770265B2

    公开(公告)日:2004-08-03

    申请号:US10209934

    申请日:2002-08-02

    IPC分类号: A61K716

    CPC分类号: A61K6/033 A61K6/0029

    摘要: A tooth surface treatment material and method to eliminate a smear layer, to deliver an inorganic component of a tooth structure in a dental cavity to the tooth structure to make a glass ionomer cement firmly adhere particularly to a dentin which includes an aqueous solution containing 2˜30% by weight of a water-soluble calcium salt and an acid which does not react with the calcium salt by ½ or less of the weight of the calcium salt and having a pH of 2 or less and an aqueous solution containing a water-soluble phosphate other than a calcium salt, or an aqueous solution containing 2˜30% by weight of a water-soluble calcium salt and an aqueous solution containing 2˜30% by weight of a water-soluble phosphate other than a calcium salt and an acid which does not react with the phosphate by ½ or less of the weight of the phosphate and having a pH of 2 or less, the acid-containing aqueous solution being first applied, and the other solution being subsequently applied onto the teeth surface.

    摘要翻译: 一种牙齿表面处理材料和消除涂抹层的方法,将牙腔中的齿结构的无机成分输送到牙齿结构,使玻璃离聚物粘结剂牢固地粘附到牙本质上,牙本质含有含2〜 30重量%的水溶性钙盐和不与钙盐反应的酸的重量为钙盐重量的1/2或更低,pH为2或更低的水和含有水溶性的水溶液 或不含钙盐的磷酸盐,或含有2〜30重量%的水溶性钙盐和含有2〜30重量%的钙盐和酸的水溶性磷酸盐的水溶液的水溶液 其不与磷酸盐反应1/2以下的磷酸盐重量且pH为2以下,首先施加含酸水溶液,并且将另一种溶液随后施加到牙齿表面上 。