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1.发明公开公开(公告)号：US20230141045A1
公开(公告)日：2023-05-11
申请号：US17884667
申请日：2022-08-10
发明人： Hong-Seok SEO , Dong Hoon SONG , Jeong Won PARK , CHUL HUH
IPC分类号： G01N21/552 , C12Q1/686
CPC分类号： G01N21/554 , C12Q1/686
摘要： Disclosed is a PCR diagnosis apparatus, which includes a transmitter including a multi-wavelength light source for outputting a first light source signal and a second light source signal having different wavelengths, and that applies the first light source signal and the second light source signal to a PCR chip including samples each including a plurality of DNAs, a code generator that generates first code signal and second code signal corresponding to the first light source signal and the second light source signal, respectively, and which are orthogonal to each other, and a receiver that performs a dot product on fluorescent data and each of the first code signal and the second code signal, wherein the fluorescent data include a first fluorescent signal and a second fluorescent signal emitted from a phosphor attached to each of the plurality of DNAs.
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公开(公告)号：US20220181838A1
公开(公告)日：2022-06-09
申请号：US17393655
申请日：2021-08-04
发明人： Dong Hoon SONG , Hong-Seok SEO , CHUL HUH
IPC分类号： H01S3/11 , H01S3/0941 , H01S3/106 , H01S3/10 , H01S3/13 , H01S3/131 , H01S3/081 , H01S3/094 , H01S3/16
摘要： A femtosecond pulse laser apparatus includes a pump light source configured to provide a pump light, a gain medium configured to obtain a gain of a laser light using the pump light, a first curved mirror and a second curved mirror, which are provided at both sides of the gain medium, an output mirror configured to transmit a portion of the laser light and reflect the other portion of the laser light to the gain medium, a mode locking portion configured to generate a femtosecond pulse of the laser light, and an acoustic wave generator configured to provide an acoustic wave into the gain medium so as to adjust self-phase modulation of the laser light.
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公开(公告)号：US20220163452A1
公开(公告)日：2022-05-26
申请号：US17618205
申请日：2020-07-14
发明人： Won Kyoung LEE , Hong-Seok SEO
IPC分类号： G01N21/65 , G01N33/483
摘要： Disclosed is a spectroscopic apparatus includes a laser irradiation device that receives an orthogonal code including a series of bits each having a first value or a second value, generates a control signal having a pulse that has a width shorter than a width of a bit section in the bit section corresponding to a bit having the first value, generates a pulsed laser beam having a pulse width shorter than the bit section using the pulse as a trigger, and irradiates an incident beam including the generated pulsed laser beam to a sample, and a detector that receives a detection signal generated from the sample and the orthogonal code, generates an orthogonal code signal of the same waveform as that of the incident beam, based on the orthogonal code, and demodulates a Raman signal, based on a correlation between the generated orthogonal code signal and the Raman signal.
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公开(公告)号：US20230408410A1
公开(公告)日：2023-12-21
申请号：US18115382
申请日：2023-02-28
发明人： Hong-Seok SEO , Dong Hoon SONG , Jeong Won PARK , CHUL HUH
IPC分类号： G01N21/64
CPC分类号： G01N21/6428 , G01N2021/6439 , G01N2201/08 , G01N2201/0612 , G01N2201/0697
摘要： Disclosed is a PCR diagnosis apparatus. This apparatus includes a PCR chip configured to store a PCR sample, a light source part configured to generate laser light to be provided to the PCR sample, an optical modulator provided between the light source part and the PCR chip and configured to selectively provide the laser light to the PCR sample according to a code, a sensor configured to detect fluorescent light generated in the PCR sample by the laser light, and a code generator connected between the optical modulator and the sensor and configured to transmit an orthogonal code to the optical modulator and the sensor.
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公开(公告)号：US20230223732A1
公开(公告)日：2023-07-13
申请号：US17982652
申请日：2022-11-08
发明人： Dong Hoon SONG , Hong-Seok SEO , Soo Jun PARK , Ho-Youl JUNG , CHUL HUH
CPC分类号： H01S3/094096 , H01S3/0941 , H01S3/10023 , H01S3/1109 , H01S3/0071 , H01S3/08059 , G02B5/10
摘要： Provided are a laser device and an optical apparatus including the same. The laser device includes a pump light source configured to provide pump light, a gain medium configured to acquire a gain of seed laser light by using the pump light, a first curved mirror and a second curved mirror, which are provided at both sides of the gain medium to reflect the seed laser light into the gain medium, an output mirror configured to transmit a portion of the seed laser light reflected by the second curved mirror and reflect the other portion of the seed laser light to the gain medium, a first acoustic wave generator connected to the gain medium and configured to provide a first photoacoustic wave in the gain medium, and a second acoustic wave generator connected to the gain medium and configured to provide a second photoacoustic wave in the gain medium.
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公开(公告)号：US20170293020A1
公开(公告)日：2017-10-12
申请号：US15477133
申请日：2017-04-03
发明人： Min Hyup SONG , Bong Ki MHEEN , Hong-Seok SEO , Gyu Dong CHOI
CPC分类号： G01S7/484 , G01S7/4806 , G01S7/4811 , G01S7/4814 , G01S7/4865 , G01S17/026 , G01S17/89 , G01S17/936
摘要： Provided is a scanning device including a transmission module configured to divide a scan target into a plurality of scan areas and alternately irradiate a first laser light and a second laser light to the scan areas that are sequentially arranged, a reception module configured to receive laser lights reflected from each of the scan areas, and an image generation module configured to generate divided images of each of the scan areas by using the reflected laser lights and generate a whole image of the scan target based on the divided images and an edge component of the reflected laser lights, wherein the transmission module is configured to trigger a rising edge of a trigger signal to generate the first laser light and trigger a falling edge of the trigger signal to generate the second laser light.
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公开(公告)号：US20170264878A1
公开(公告)日：2017-09-14
申请号：US15208577
申请日：2016-07-12
发明人： Min Hyup SONG , Bong Ki MHEEN , Hong-Seok SEO , Gyu Dong CHOI
CPC分类号： H04N13/156 , G01S17/89 , H04N13/218 , H04N13/254
摘要： Provided herein is a scanning device including a transmitting module dividing a subject into a plurality of image regions and emitting laser beam onto the plurality of image regions by an interlaced method, a receiving module receiving reflected laser beam from the subject, and a signal processing module scanning a shape of the subject by a Time Of Flight (TOF) technique based on the reflected laser beam, wherein the signal processing module generates a single image with respect to the shape of the subject by overlapping subframes generated by the interlaced method.
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8.发明公开公开(公告)号：US20240060896A1
公开(公告)日：2024-02-22
申请号：US18366429
申请日：2023-08-07
发明人： Hong-Seok SEO , Dong Hoon SONG , Jeong Won PARK , Chul Huh
CPC分类号： G01N21/645 , G01N21/6428 , C12Q1/686 , C12Q2563/107 , G01N2021/6484 , G01N2201/06146 , G01N2021/6471 , G01N2021/6441 , G01N2021/6432
摘要： An apparatus for polymerase chain reaction (PCR) diagnosis for normalizing light source power and fluorescence power and an operating method thereof are disclosed.
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公开(公告)号：US20220137387A1
公开(公告)日：2022-05-05
申请号：US17460478
申请日：2021-08-30
发明人： Sang Kyun LEE , Dong Hoon SONG , Hong-Seok SEO , Chul HUH
摘要： Provided are a pulse compressor and a two-photon excited fluorescence microscope. The microscope includes a light source which generates a laser beam having a pulse, a pulse compressor which compresses the pulse of the laser beam, an objective lens which provides the laser beam to a specimen, and image sensors which receive the laser beam and obtain images of the specimen. The pulse compressor may include a grating plate, a corner cube provided on one side of the grating plate, and a retroreflector provided on the other side of the grating plate.
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公开(公告)号：US20210123807A1
公开(公告)日：2021-04-29
申请号：US17014258
申请日：2020-09-08
发明人： Won Kyoung LEE , Hong-Seok SEO
摘要： A spectroscopic apparatus includes a splitter that receives a first detected signal output from a sample to which an incident beam is irradiated, and outputs a reflected signal and a second detected signal by splitting the first detected signal, and a signal processor that receives the reflected signal and the second detected signal, and extracts a Raman signal from the second detected signal in response to the received reflected signal.
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