公开(公告)号：US08613845B2

公开(公告)日：2013-12-24

申请号：US12921293

申请日：2009-03-06

申请人： Elizabeth Jane Maxwell ,  Xuefei Zhong ,  Hong Zhang ,  David Da Yong Chen

发明人： Elizabeth Jane Maxwell ,  Xuefei Zhong ,  Hong Zhang ,  David Da Yong Chen

IPC分类号： G01N27/453 ,  H01J49/04

CPC分类号： G01N27/4473 ,  B05B5/0255 ,  G01N27/447 ,  G01N30/7266 ,  H01J49/0431 ,  H01J49/167

摘要： A complete capillary electrophoresis (CE) system that is capable of providing a continuous flow of effluent at the exit of the flow-through outlet vial is provided. A self-contained capillary electrophoresis system with a flow-through outlet vial for interfacing with mass spectrometry includes a capillary having an upstream inlet end and a downstream terminus end; an electrically conductive hollow needle having an inner wall defining an internal tapered chamber, the internal tapered chamber dimensioned and configured to slidably accept the terminus end of the capillary, the capillary longitudinally inserted into and mounted within the internal tapered chamber to a distance whereby the terminus end of the capillary abuts the inner wall of the needle at the taper; and wherein a micro-reservoir is formed between the terminus end of the capillary and the downstream exit orifice.

摘要翻译： 提供了一种完整的毛细管电泳（CE）系统，其能够在流过出口小瓶的出口处提供连续的流出物流。 具有用于与质谱联用的流通出口小瓶的独立毛细管电泳系统包括具有上游入口端和下游终端的毛细管; 导电中空针头，其具有限定内部锥形腔室的内壁，所述内部锥形腔室的尺寸和构造可滑动地接纳毛细管的末端，毛细管纵向插入并安装在内部锥形腔室内一段距离， 毛细管的端部以锥度与针头的内壁相接; 并且其中在所述毛细管的末端和所述下游出口之间形成微贮器。

公开(公告)号：US20110042216A1

公开(公告)日：2011-02-24

申请号：US12921293

申请日：2009-03-06

申请人： Elizabeth Jane Maxwell ,  Xuefei Zhong ,  Hong Zhang ,  David Da Yong Chen

发明人： Elizabeth Jane Maxwell ,  Xuefei Zhong ,  Hong Zhang ,  David Da Yong Chen

IPC分类号： G01N27/447

CPC分类号： G01N27/4473 ,  B05B5/0255 ,  G01N27/447 ,  G01N30/7266 ,  H01J49/0431 ,  H01J49/167

摘要： A complete capillary electrophoresis (CE) system that is capable of providing a continuous flow of effluent at the exit of the flow-through outlet vial is provided. A self-contained capillary electrophoresis system with a flow-through outlet vial for interfacing with mass spectrometry includes a capillary having an upstream inlet end and a downstream terminus end; an electrically conductive hollow needle having an inner wall defining an internal tapered chamber, the internal tapered chamber dimensioned and configured to slidably accept the terminus end of the capillary, the capillary longitudinally inserted into and mounted within the internal tapered chamber to a distance whereby the terminus end of the capillary abuts the inner wall of the needle at the taper; and wherein a micro-reservoir is formed between the terminus end of the capillary and the downstream exit orifice.

摘要翻译： 提供了一种完整的毛细管电泳（CE）系统，其能够在流过出口小瓶的出口处提供连续的流出物流。 具有用于与质谱联用的流通出口小瓶的独立毛细管电泳系统包括具有上游入口端和下游终端的毛细管; 导电中空针头，其具有限定内部锥形腔室的内壁，所述内部锥形腔室的尺寸和构造可滑动地接纳毛细管的末端，毛细管纵向插入并安装在内部锥形腔室内一段距离， 毛细管的端部以锥度与针头的内壁相接; 并且其中在所述毛细管的末端和所述下游出口之间形成微贮器。