公开(公告)号：US20120143071A1

公开(公告)日：2012-06-07

申请号：US13156489

申请日：2011-06-09

申请人： Bernard F. Hete ,  Eric J. Ayers ,  Eric W. Starr

发明人： Bernard F. Hete ,  Eric J. Ayers ,  Eric W. Starr

IPC分类号： A61B5/02

CPC分类号： A61B5/02416 ,  A61B5/7257 ,  A61B2503/40

摘要： A noninvasive photoplethysmographic sensor system for mobile animals such as small rodents, namely rats and mice is useful such as in a laboratory research environment. The noninvasive photoplethysmographic sensor for mobile animals such as small rodents utilizes multiple FFT's in the processing of the phtotoplethysmograophic signal, where each FFT has a different time record of the signals such as a number of points, or a zero padded FFTs. The noninvasive photoplethysmographic sensor for mobile animals provides actigraphy measurements for the animal.

摘要翻译： 用于诸如小鼠和小鼠之类的移动动物的无创光电体积描记传感器系统是有用的，例如在实验室研究环境中。 用于诸如小型啮齿动物的移动动物的非侵入性光电容积描记传感器在处理噬菌体同位素信号时利用多个FFT，其中每个FFT具有诸如点数或零填充FFT之类的信号的不同时间记录。 用于移动动物的无创光电体积描记传感器为动物提供了动态测量。

公开(公告)号：US20100160751A1

公开(公告)日：2010-06-24

申请号：US12704024

申请日：2010-02-11

申请人： Bernard F. Hete ,  Eric W. Starr ,  Eric J. Ayers

发明人： Bernard F. Hete ,  Eric W. Starr ,  Eric J. Ayers

IPC分类号： A61B5/1455

CPC分类号： G01N33/4925 ,  A61B5/14557

摘要： A blood oxygenation monitoring device may comprise an extracorporeal pulse simulation system including one at least partially transparent blood holding element with a photoplethysmographic sensor coupled to the element and adapted to measure particular gas content of the blood. The system includes a pulse simulation mechanism configured to simulate pulsatile behavior of the blood within the element relative to the photoplethysmographic sensors. The blood holding element may be a reservoir, wherein the pulse simulation mechanism includes a magnetic stirrer and stir bar within the reservoir. The blood holding member may be flexible tubing having blood flow there through, wherein the pulse simulation mechanism is a peristaltic pump coupled to the tubing. The monitoring device can rapidly and accurately form oxygen dissociation curves. The monitoring device can be utilized in conjunction with a heart lung bypass machine or other extra corporeal circuit devices or can be a calibration tool for sensors.

摘要翻译： 血氧监测装置可以包括体外脉冲模拟系统，其包括一个至少部分透明的血液保持元件，其具有耦合到该元件的光电容积传感器传感器，并且适于测量血液的特定气体含量。 该系统包括脉冲模拟机构，其被配置为模拟元件内相对于光电容积传感器的血液的脉动行为。 血液保持元件可以是储存器，其中脉冲模拟机构包括储存器内的磁力搅拌器和搅拌棒。 血液保持构件可以是具有血液流过的柔性管，其中脉冲模拟机构是联接到管道的蠕动泵。 监测装置可以快速准确地形成氧解离曲线。 监测装置可以与心脏肺旁路机或其他额外的物理电路装置结合使用，或者可以是用于传感器的校准工具。

公开(公告)号：US20090099425A1

公开(公告)日：2009-04-16

申请号：US12249044

申请日：2008-10-10

申请人： Eric W. Starr ,  Bernard F. Hete ,  Eric J. Ayers

发明人： Eric W. Starr ,  Bernard F. Hete ,  Eric J. Ayers

IPC分类号： A61B5/1455 ,  A61B5/0205 ,  A61B5/022

CPC分类号： A61B5/02255 ,  A61B5/14552 ,  A61B2503/40

摘要： An integrated tail mounted blood pressure monitor and pulse oximeter system includes a tail blood flow occlusion member configured to selectively occlude blood flow through the tail; a sensor coupled to the tail blood flow occlusion member detecting a degree of operation thereof; Light sources coupled to the tail closer to the distal end of the tail than the tail blood flow occlusion member, and selectively directing light of two different wavelengths into the tail; a light receiver coupled to the tail and selectively receiving a signal associated with light directed into the tail from the light sources; and a controller configured to selectively determine blood pressure parameters from the data and pulse oximeter parameters from the data.

摘要翻译： 综合的尾部安装的血压监测器和脉搏血氧计系统包括构造成选择性地阻塞穿过尾部的血流的尾部血流阻塞构件; 耦合到所述尾部血流阻塞构件的传感器，其检测其操作程度; 耦合到尾部的光源比尾部血流阻塞构件更靠近尾部的远端，并且选择性地将两种不同波长的光引导到尾部中; 耦合到尾部的光接收器并且选择性地接收与从光源引导到尾部中的光相关联的信号; 以及控制器，被配置为从数据中选择性地从数据和脉搏血氧计参数确定血压参数。

公开(公告)号：US20080194932A1

公开(公告)日：2008-08-14

申请号：US11972595

申请日：2008-01-10

申请人： Eric J. Ayers ,  Bernard F. Hete ,  Eric W. Starr

发明人： Eric J. Ayers ,  Bernard F. Hete ,  Eric W. Starr

IPC分类号： A61B5/1455

CPC分类号： A61B5/14551 ,  A61B5/0205 ,  A61B5/0816 ,  A61B5/742 ,  A61B2503/40

摘要： A user interface for a pulse oximetry device that calculates physiologic parameters of a subject including at least a subject's heart rate and SpO2, is disclosed wherein the interface comprises a graphical display of at least one raw data signal of the pulse oximetry device that maintains heart and breath rate components and a display of the calculated heart rate and SpO2 of the subject. The interface may further include a user selectable data averaging function in which the interface is configured to selectively obtain and display averages of at least some of the calculated physiologic parameters over a defined period.

摘要翻译： 公开了一种脉搏血氧饱和度测量装置的用户界面，其用于计算包括至少一个对象的心率和主观心理状况的对象的生理参数，其中该界面包括图形 显示维持心脏和呼吸速率分量的脉搏血氧饱和度测量装置的至少一个原始数据信号，并显示所述对象的计算心率和计算心率和S 。 接口还可以包括用户可选择的数据平均功能，其中接口被配置为在规定的周期内选择性地获得和显示所计算的生理参数中的至少一些的平均值。

公开(公告)号：US20080132770A1

公开(公告)日：2008-06-05

申请号：US11951194

申请日：2007-12-05

申请人： Eric J. Ayers ,  Bernard F. Hete ,  Eric W. Starr

发明人： Eric J. Ayers ,  Bernard F. Hete ,  Eric W. Starr

IPC分类号： A61B5/00 ,  A61B5/08

CPC分类号： G01D1/14 ,  A61B5/1455 ,  A61B5/7264 ,  G16H40/63

摘要： A method and apparatus of obtaining research data that includes a set of physiologic parameters of a subject by utilizing a physiologic sensor which measures a plurality of physiologic parameters of a subject by obtaining signals from the sensor from which the physiologic parameters are calculated and which verifies the calculated parameters with preset criteria, comprising the steps of: Providing a plurality of distinct error classification codes for the calculated parameters, wherein each error classification code is associated with a given set of failed criteria; Recording the calculated parameters of the subject over a session period; Assigning error classification codes to calculated parameters that failed to meet the given criteria; and Recording the assigned error codes in a time integrated manner with the calculated parameters of the subject over a session period. The Error codes may be visibly displayed to the user in a variety of formats.

摘要翻译： 一种获取研究数据的方法和装置，所述研究数据包括一组生物学参数，所述研究数据通过利用生理学传感器，所述生理学传感器通过从所述传感器获得来自所述生理参数的信号来测量受试者的多个生理参数， 具有预设标准的计算参数，包括以下步骤：为所计算的参数提供多个不同的错误分类代码，其中每个错误分类代码与给定的一组失败标准相关联; 在会话期间记录受试者的计算参数; 将错误分类代码分配给不符合给定标准的计算参数; 并且以与会话期间的被摄体的计算参数以时间积分的方式记录分配的错误代码。 错误代码可能以各种格式可见地显示给用户。

公开(公告)号：US20130085354A1

公开(公告)日：2013-04-04

申请号：US13626083

申请日：2012-09-25

申请人： Bernard F. Hete ,  Eric J. Ayers

发明人： Bernard F. Hete ,  Eric J. Ayers

IPC分类号： A61B5/1455 ,  A61B5/0205

CPC分类号： A61B5/14551 ,  A61B5/0205 ,  A61B5/02405 ,  A61B5/02416 ,  A61B5/0816 ,  A61B5/7207 ,  A61B5/7253 ,  A61B5/7257 ,  A61B5/7278

摘要： Several techniques are disclosed for isolating either heart or breath rate data from a photoplethysmograph, which is a time domain signal such as from a pulse oximeter. The techniques involve the use of filtering in the frequency domain, after a Fast Fourier Transform (FFT) has been conducted on a given photoplethysmograph also references as a given set of discrete time-domain data. The filtering may be applied to an identified fundamental frequency and one or more harmonics for heart related parameters. The filter may be truncated to the frequency data set and further applied multiple times to improve roll off. After filtering, an Inverse FFT (IFFT) is used to reconstruct the time-domain signal, except with undesirable frequency content eliminated or reduced. Calculation or measurement of parameters is then conducted on this reconstructed time-domain signal.

摘要翻译： 公开了几种用于从例如来自脉搏血氧计的时间域信号的光电体积描记器中分离心脏或呼吸速率数据的技术。 在对给定的光电体积描记仪进行快速傅里叶变换（FFT）之后，技术还涉及在频域中使用滤波，也可以将参考作为一组给定的离散时域数据。 滤波可以应用于所识别的基频和用于心脏相关参数的一个或多个谐波。 滤波器可以被截断为频率数据集，并进一步应用多次以改善滚降。 滤波后，使用逆FFT（IFFT）重建时域信号，除了消除或减少不期望的频率内容。 然后对该重构的时域信号进行参数的计算或测量。

公开(公告)号：US20100145170A1

公开(公告)日：2010-06-10

申请号：US12473244

申请日：2009-05-27

申请人： Eric J. Ayers ,  Bernard F. Hete ,  Patrick W. Truitt

发明人： Eric J. Ayers ,  Bernard F. Hete ,  Patrick W. Truitt

IPC分类号： A61B5/1455

CPC分类号： A61B5/02416 ,  A61B5/02405 ,  A61B5/0816 ,  A61B5/1455 ,  A61B5/7203 ,  G16H15/00 ,  G16H40/63

摘要： A user interface for a pulse oximetry device that calculates physiologic parameters of a subject including at least a subject's heart rate and SpO2, is disclosed wherein the interface comprises a graphical display of at least one raw data signal of the pulse oximetry device that maintains heart and breath rate components and a display of the calculated heart rate and SpO2 of the subject. The interface may further include a user selectable data averaging function in which the interface is configured to selectively obtain and display averages of at least some of the calculated physiologic parameters over a defined period. The interface may further include a user selectable noise suppression function for the displayed data.

摘要翻译： 公开了一种用于计算包括至少受试者的心率和SpO2的对象的生理参数的脉搏血氧饱和度测量装置的用户界面，其中所述界面包括维持心脏的脉搏血氧仪装置的至少一个原始数据信号的图形显示， 呼吸速率组分和显示计算的心率和受试者的SpO2。 接口还可以包括用户可选择的数据平均功能，其中接口被配置为在规定的周期内选择性地获得和显示所计算的生理参数中的至少一些的平均值。 接口还可以包括用于所显示的数据的用户可选噪声抑制功能。

公开(公告)号：US20080262326A1

公开(公告)日：2008-10-23

申请号：US12106781

申请日：2008-04-21

申请人： Bernard F. Hete ,  Eric J. Ayers

发明人： Bernard F. Hete ,  Eric J. Ayers

IPC分类号： A61B5/1455

CPC分类号： A61B5/14551 ,  A61B5/02416 ,  A61B5/0816

摘要： A signal processing method of processing a physiologic signal, such as a Photoplethysmography Signal having at least some cardiac components and/or respirator components in the physiologic signal, the processing including the steps of: Identifying a potential cardiac and or respiratory components of a physiologic signal wherein the potential cardiac and or respiratory components have a series of peaks and valleys; Calculating a comparison of the durations of a peak to valley sub-component and a valley to peak sub component of the potential cardiac and or respiratory components; and Utilizing the calculated comparison to evaluate the potential cardiac and or respiratory components.

摘要翻译： 一种处理生理信号的信号处理方法，例如在生理信号中具有至少一些心脏成分和/或呼吸器成分的光电体积描记信号，所述处理包括以下步骤：识别生理信号的潜在心脏和/或呼吸成分 其中所述潜在心脏和/或呼吸成分具有一系列峰和谷; 计算潜在的心脏和/或呼吸成分的峰谷亚组分的持续时间和谷到峰次分量的比较; 并利用计算的比较来评估潜在的心脏和/或呼吸成分。

公开(公告)号：US20090275810A1

公开(公告)日：2009-11-05

申请号：US12485902

申请日：2009-06-16

申请人： Eric J. Ayers ,  Eric W. Starr

发明人： Eric J. Ayers ,  Eric W. Starr

IPC分类号： A61B5/00 ,  G08B23/00

CPC分类号： A61B5/0205 ,  A61B5/7475 ,  A61B2503/40 ,  A61B2560/0443

摘要： A portable modular kiosk based physiologic sensor system for clinical and research applications configured to simultaneously utilize multiple sensors with cross checking and cross calculation of physiologic parameters and configured for continuous monitoring of blood oxygenation and respiratory parameters.

摘要翻译： 一种用于临床和研究应用的便携式模块化基站生理传感器系统，被配置为同时利用多个传感器进行交叉检查和交叉计算生理参数，并被配置用于持续监测血氧和呼吸参数。

公开(公告)号：US20080167564A1

公开(公告)日：2008-07-10

申请号：US11972431

申请日：2008-01-10

申请人： Benard F. Hete ,  Eric J. Ayers

发明人： Benard F. Hete ,  Eric J. Ayers

IPC分类号： A61B5/024 ,  A61B5/08 ,  A61B5/00

CPC分类号： A61B5/02416 ,  A61B5/02405 ,  A61B5/0816 ,  A61B5/0823 ,  A61B5/1455 ,  A61B5/7207 ,  A61B5/7253 ,  A61B5/7257

摘要： Several techniques are disclosed for isolating either heart or breath rate data from a photoplethysmograph, which is a time domain signal such as from a pulse oximeter. The techniques involve the use of filtering in the frequency domain, after a Fast Fourier Transform (FFT) has been conducted on a given photoplethysmograph also references as a given set of discrete time-domain data. The filtering may be applied to an identified fundamental frequency and one or more harmonics for heart related parameters. The filter may be truncated to the frequency data set and further applied multiple times to improve roll off. After filtering, an Inverse FFT (IFFT) is used to reconstruct the time-domain signal, except with undesirable frequency content eliminated or reduced. Calculation or measurement of parameters is then conducted on this reconstructed time-domain signal.

摘要翻译： 公开了几种用于从例如来自脉搏血氧计的时间域信号的光电体积描记器中分离心脏或呼吸速率数据的技术。 在对给定的光电体积描记仪进行快速傅里叶变换（FFT）之后，技术还涉及在频域中使用滤波，也可以将参考作为一组给定的离散时域数据。 滤波可以应用于所识别的基频和用于心脏相关参数的一个或多个谐波。 滤波器可以被截断为频率数据集，并进一步应用多次以改善滚降。 滤波后，使用逆FFT（IFFT）重建时域信号，除了消除或减少不期望的频率内容。 然后对该重构的时域信号进行参数的计算或测量。