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1.发明授权Method for detection of gram-negative bacterial liposaccharides in biological fluids 失效检测生物体液中革兰氏阴性细菌脂肪糖的方法
公开(公告)号：US5356778A
公开(公告)日：1994-10-18
申请号：US972498
申请日：1993-02-05
IPC分类号： G01N33/53 , G01N33/569 , G01N33/577 , G01N33/579
CPC分类号： G01N33/579 , G01N33/56916 , G01N33/577 , Y10S435/81 , Y10S435/879 , Y10S436/815 , Y10S436/821
摘要： The invention relates to a method of detecting gram-negative bacterial endotoxin using antibody capture combined with amoebocyte lysate chromogenic detection. The method is highly sensitive and rapid and may be used for detection of specific endotoxin. In a particular application, picogram levels of Haemophilus influenzae type b endotoxin are detected in plasma taken from previously infected mammals. In another particular application, the method is applied to the detection and diagnosis of disease, through the detection of endotoxin from disease-causing organisms. A specific example is the diagnosis of chancroid through the detection of endotoxin from H. ducreyi.
摘要翻译： PCT No.PCT / US91 / 04864 Sec。 371日期：1993年2月5日 102（e）日期1993年2月5日PCT 1991年7月10日PCT公布。 出版物WO92 / 01228 日期1992年1月23日。本发明涉及使用抗体捕获与变形细胞裂解物显色检测结合来检测革兰氏阴性细菌内毒素的方法。 该方法灵敏度高，可快速检测特异性内毒素。 在特定应用中，从先前感染的哺乳动物的血浆中检测到流感嗜血杆菌b型内毒素的皮克水平。 在另一个具体应用中，该方法通过检测来自致病生物体的内毒素来应用于疾病的检测和诊断。 一个具体的例子是通过检测杜氏红细菌中的内毒素来诊断黄疸。
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2.发明授权Method for detection of gram-negative bacterial lipopolysaccharides in biological fluids 失效用于检测生物流体中的甘草酸性脂多糖的方法
公开(公告)号：US5198339A
公开(公告)日：1993-03-30
申请号：US553072
申请日：1990-07-13
IPC分类号： G01N33/53 , G01N33/569 , G01N33/577 , G01N33/579
CPC分类号： G01N33/579 , G01N33/56916 , G01N33/577 , Y10S435/81 , Y10S435/879 , Y10S436/815 , Y10S436/821
摘要： The invention relates to a method of detecting gram-negative bacterial endotoxin using antibody capture combined with amoebocyte lysate chromogenic detection. The method is highly sensitive and rapid and may be used for detection of specific endotoxin. In a particular application, picogram levels of Haemophilus influenzae are detected in plasma taken from previously infected mammals.
摘要翻译： 本发明涉及使用抗体捕获与变形细胞裂解物显色检测结合来检测革兰氏阴性细菌内毒素的方法。 该方法灵敏度高，可快速检测特异性内毒素。 在特定应用中，从先前感染的哺乳动物的血浆中检测到流感嗜血杆菌的皮克水平。
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公开(公告)号：US08775603B2
公开(公告)日：2014-07-08
申请号：US11744809
申请日：2007-05-04
申请人： Eric J. Hansen
发明人： Eric J. Hansen
IPC分类号： G06F15/173 , H04L29/08 , G06Q30/02
CPC分类号： H04L67/2819 , G06Q30/02 , H04L67/02 , H04L67/22 , H04L67/28
摘要： The invention is a method and system for testing variations of website content useful to optimize website visitor conversions. The invention helps website operators create content variations, and then scientifically test and measure the impact of those variations on conversion rates. The invention includes a method of using a reverse proxy server to introduce page variations on existing website content without needing to modify the existing web server. Using the reverse proxy server, the invention automatically injects values, associated with website variations, into web page tags used with web analytics platforms. The invention makes it possible to test any number of website variations and access such data from within web analytics platforms. The invention also provides a method to automatically transform web page tags of a first web analytics platform to web page tags of a second web analytics platform to easily try new third party web analytics solutions.
摘要翻译： 本发明是一种用于测试网站内容的变化的方法和系统，其用于优化网站访问者转换。 本发明有助于网站营运者创建内容变化，然后科学测试和衡量这些变化对转化率的影响。 本发明包括使用反向代理服务器来在现有网站内容上引入页面变体的方法，而不需要修改现有的web服务器。 使用反向代理服务器，本发明自动将与网站变体相关联的值注入到与网络分析平台一起使用的网页标签中。 本发明使得可以测试任何数量的网站变体并从网络分析平台中访问这些数据。 本发明还提供了一种自动将第一网络分析平台的网页标签转换成第二网络分析平台的网页标签以方便地尝试新的第三方网络分析解决方案的方法。
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公开(公告)号：US08338354B2
公开(公告)日：2012-12-25
申请号：US13033228
申请日：2011-02-23
CPC分类号： D06L1/00 , A47L13/00 , A47L13/26 , B01J13/0095 , B05B11/3084 , B65D83/202 , B65D83/68 , C11D3/0031 , C11D3/0047 , C11D3/3947 , C11D17/0043 , C11D17/041 , D06L1/02 , D06L1/04 , D06L4/10 , D06L4/12 , D06L4/18
摘要： A manual spray cleaner for removing dirt and stains from fabrics and carpets comprising a spray bottle having two separate chambers and a single dispensing spray outlet for dispensing controlled amounts of liquids from each of the chambers. One of the chambers has a fabric/carpet cleaning composition therein and the other chamber has an oxidizing composition that enhances the cleanability of the fabric/carpet cleaning composition. The fabric/carpet cleaning composition and the oxidizing composition are simultaneously drawn from their respective chambers and mixed together at the time that they are dispensed from the spray bottle. At least one of the oxidizing composition and the fabric/carpet cleaning composition includes a fabric/carpet protectant. The two compositions are mixed before or after they are sprayed from the bottle. The two compositions can be pressurized with an aerosol propellant or drawn from their respective chambers by a mechanical pump.
摘要翻译： 一种手动喷雾清洁器，用于从织物和地毯上除去污垢和污渍，其中包括具有两个独立室的喷雾瓶和用于从每个室分配受控量的液体的单个分配喷雾出口。 其中一个室具有织物/地毯清洁组合物，另一个室具有提高织物/地毯清洁组合物的可清洁性的氧化组合物。 织物/地毯清洁组合物和氧化组合物在从喷雾瓶分配的同时从它们各自的室同时抽出并混合在一起。 氧化组合物和织物/地毯清洁组合物中的至少一种包括织物/地毯保护剂。 两种组合物在从瓶子喷射之前或之后混合。 两种组合物可以用气溶胶推进剂加压，或者通过机械泵从它们各自的室抽出。
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公开(公告)号：US20120168971A1
公开(公告)日：2012-07-05
申请号：US13334841
申请日：2011-12-22
CPC分类号： A47L11/4088 , A47L1/09 , A47L7/0004 , A47L11/4086 , A47L13/38
摘要： A mist generating system for a cleaning implement is adapted to generate a finely atomized liquid mist for suppressing dust, allergens, and other airborne particulates. The mist generating system can be adapted to fit many cleaning implements such as vacuum cleaners, wet extraction cleaners, floor mops, and dusters to suppress airborne dust and particulates generated during operation and the cleaning process.
摘要翻译： 用于清洁工具的雾气发生系统适于产生用于抑制灰尘，变应原和其它空气中的微粒的细雾化液雾。 雾气发生系统可适用于诸如真空吸尘器，湿式清洗器，地板拖把和除尘器之类的许多清洁工具，以抑制在操作和清洁过程中产生的空气中的灰尘和微粒。
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公开(公告)号：US20110215113A1
公开(公告)日：2011-09-08
申请号：US13110512
申请日：2011-05-18
申请人： Eric J. Hansen , Kevin Haley , Jesse J. Williams , Herbert J. VanderBilt , Michael R. Foote , Donald J. Mahaffy
发明人： Eric J. Hansen , Kevin Haley , Jesse J. Williams , Herbert J. VanderBilt , Michael R. Foote , Donald J. Mahaffy
CPC分类号： B65D83/202 , B65D83/206 , B65D83/62 , B65D83/68 , C09K3/30 , C12N9/001 , C12N15/8247
摘要： A manual spray dispenser for dispensing a mixture of two compositions comprises a container having a first and second chamber and a single dispensing spray outlet. At least one of the chambers has a separator in the form of a pouch for physically separating the contents of the container from an interior surface of the chamber. One of the first and second chambers contains a first composition and the other contains a second composition. The dispenser further contains a dispensing system for simultaneously dispensing the first composition and the second composition, mixing the two compositions together, and dispensing a mixture of the two compositions from the container under pressure. An aerosol propellant is between the separator and the interior surface of the at least one of the first and second chambers for pressurizing the composition in the pouch for dispensing the contents thereof through the dispensing system under pressure.
摘要翻译： 用于分配两种组合物的混合物的手动喷雾分配器包括具有第一和第二室和单个分配喷雾出口的容器。 至少一个腔室具有用于将容器的内容物与室的内表面物理分离的小袋形式的分离器。 第一和第二室中的一个包含第一组合物，另一个包含第二组合物。 分配器还包含用于同时分配第一组合物和第二组合物的分配系统，将两种组合物混合在一起，并在压力下从容器中分配两种组合物的混合物。 气雾剂推进剂位于分离器和第一和第二室中的至少一个室的内表面之间，用于对袋中的组合物加压，用于在压力下通过分配系统分配其内容物。
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公开(公告)号：US20100154822A1
公开(公告)日：2010-06-24
申请号：US12641517
申请日：2009-12-18
CPC分类号： A47L13/26 , A47L13/12 , C11D17/041
摘要： A package for delivering a cleaning solution to a surface to be cleaned comprises a housing, a pocket in the housing having at least one piercing projection extending into the pocket and a passageway between the pocket and the surface to be cleaned beneath the housing. A sealed packet containing a cleaning solution can be configured to fit into the pocket and can have at least a portion of an outer surface thereof adapted to be pierced by the at least one piercing projection when the packet is placed in the pocket. The cleaning solution can be discharged from the packet when the packet is positioned in the pocket and the packet is pierced by the at least one piercing projection. The cleaning solution can then be dispensed through the passageway onto a surface to be cleaned.
摘要翻译： 用于将清洁溶液输送到要清洁的表面的包装包括壳体，壳体中的凹槽，其具有延伸到袋中的至少一个刺穿突起和在该壳体下方的待清洁表面之间的通道。 包含清洁溶液的密封包装可以构造成装配到袋中，并且当包装被放置在口袋中时，可以使其外表面的至少一部分适于被至少一个穿刺突起刺穿。 当分组被定位在口袋中并且分组被至少一个刺穿突起刺穿时，清洁溶液可以从分组中排出。 然后可以将清洁溶液通过通道分配到待清洁的表面上。
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公开(公告)号：US07021499B2
公开(公告)日：2006-04-04
申请号：US10711488
申请日：2004-09-21
IPC分类号： B67D5/60
CPC分类号： D06L1/00 , A47L13/00 , A47L13/26 , B01J13/0095 , B05B11/3084 , B65D83/202 , B65D83/68 , C11D3/0031 , C11D3/0047 , C11D3/3947 , C11D17/0043 , C11D17/041 , D06L1/02 , D06L1/04 , D06L4/10 , D06L4/12 , D06L4/18
摘要： An aerosol spray cleaner comprises two containers and a dispenser with a single dispensing spray outlet. One container has a cleaning composition and the other has an oxidizing composition. An integrally molded actuator includes a resiliently cantilevered lever connected to container valves to simultaneously open the valves to dispense the two fluids through the dispensing spray outlet. A handle extends laterally of the containers so grasp the handle and depress the actuator with a thumb.
摘要翻译： 气雾喷雾清洁器包括两个容器和具有单个分配喷雾出口的分配器。 一个容器具有清洁组合物，另一个具有氧化组合物。 整体模制的致动器包括连接到容器阀的弹性悬臂，以同时打开阀，以通过分配喷雾出口分配两种流体。 把手伸向容器的侧面，从而抓住手柄并用拇指按压致动器。
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公开(公告)号：US06934993B1
公开(公告)日：2005-08-30
申请号：US10064322
申请日：2002-07-02
CPC分类号： A47L9/0411 , A47L5/26 , A47L5/30 , A47L9/0444 , A47L9/0477
摘要： An extraction cleaning machine has a solution dispensing system and a recovery system for applying a cleaning solution to a surface and recovering the solution from the surface, and an agitation brush assembly for agitating the surface. The agitation brush assembly can include friction-type or other dampers for reducing brush bounce, and biasing elements for maintaining a constant downward force on the brush. The brush can have multiple helical rows of tufted bristles, preferably at least four rows, or can comprise a continuous helix of bristles in a twisted-wire spindle. The brush can further have a removable fabric cover for mounting over a bristle brush for contacting a surface being cleaned. The brush assembly can function in an upright extraction cleaning machine with or without an above floor cleaning tool, a hand-held extractor, or a hand-held attachment to a canister extractor or an above floor tool in upright extractor.
摘要翻译： 提取清洗机具有溶液分配系统和用于将清洁溶液施加到表面并从表面回收溶液的回收系统，以及用于搅拌表面的搅拌刷组件。 搅拌刷组件可以包括用于减少刷子弹跳的摩擦型或其它阻尼器，以及用于在刷子上保持恒定向下的力的偏置元件。 刷子可以具有多个螺旋排的簇绒刷毛，优选至少四排，或者可以在双绞丝心轴中包括连续的刷毛螺旋。 刷子可以进一步具有可移除的织物盖，用于安装在刷毛上，用于接触待清洁的表面。 刷子组件可以在具有或不具有上层地板清洁工具，手持式提取器或手提式附件的直立提取清洁机器中起作用，其直接提取器中的罐式抽取器或上述地板工具。
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公开(公告)号：US5993826A
公开(公告)日：1999-11-30
申请号：US25363
申请日：1993-03-02
IPC分类号： A61K38/00 , A61K39/00 , A61P31/04 , C07K14/21 , C07K16/12 , C12P21/08 , A61K39/102 , A61K39/02 , C07K14/285 , C07K16/102
CPC分类号： C07K16/1203 , C07K14/212 , C07K16/1214 , C07K16/1217 , A61K2039/505 , A61K38/00 , A61K39/00
摘要： The present disclosure relates to Moraxella catarrhalis outer membrane vesicle (OMV) compositions, to selected antigenic proteins from the outer membranes of M. catarrhalis which have a variety of useful properties, and to monoclonal antibodies against these proteins. Particular "Outer Membrane Proteins" (OMPs) of the invention are characterized as having molecular weights of about 30 kD, 80 kD (also termed CopB protein) and between about 200 and 700 kD (HMWP antigen). Passive immunization with monoclonal antibodies directed against these proteins confers protection against homologous and heterologous Moraxella catarrhalis strains in animal models, and active immunization with outer membrane vesicles also enhances pulmonary clearance of distinct M. catarrhalis strains. This demonstrates both the utility of antibodies in conferring passive immunity and the usefulness of OMPs, or variants thereof, in the preparation of vaccines. Also disclosed are DNA segments encoding these OMPs, methods for preparing the antigens, or variants, through the application of recombinant DNA techniques, as well as diagnostic methods and related embodiments.
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