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公开(公告)号：US5410412A
公开(公告)日：1995-04-25
申请号：US178035
申请日：1994-01-06
IPC分类号： G01N27/447 , G01N21/25
CPC分类号： G01N27/44721 , G01N27/44704 , G01N27/44782
摘要： An electrophoretic system is provided which allows for carrying out electrophoresis while monitoring and regulating the temperature and the electrical field gradient in the gel. In addition, photometric monitoring is provided so as to monitor the progress of the electrophoretic separation and vary conditions to change the progress as desired. A computer is employed which receives the signals from the electrophoretic and photometric apparatuses and regulates temperature and voltage to either maintain conditions, or change the conditions to vary the progress of the electrophoresis. Gel molds are provided for forming the lanes in a gel plate, as well as a light module, for reading the bands present in the gel lanes with the photometer.
摘要翻译： 提供了一种电泳系统，其允许进行电泳，同时监测和调节凝胶中的温度和电场梯度。 此外，提供光度监测以监测电泳分离的进展并改变条件以根据需要改变进展。 使用计算机，其接收来自电泳和光度测量装置的信号并调节温度和电压以维持条件，或改变条件以改变电泳进程。 提供凝胶模具用于在凝胶板中形成通道以及光模块，用于通过光度计读取凝胶通道中存在的条带。
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公开(公告)号：US5104512A
公开(公告)日：1992-04-14
申请号：US522325
申请日：1990-05-14
IPC分类号： G01N27/447
CPC分类号： G01N27/44721 , G01N27/44704 , G01N27/44782
摘要： An electrophoretic system is provided which allows for carrying out electrophoresis while monitoring and regulating the temperature and the electrical field gradient in the gel. In addition, photometric monitoring is provided so as to monitor the progress of the electrophoretic separation and vary conditions to change the progress as desired. A computer is employed which receives the signals from the electrophoretic and photometric apparatuses and regulates temperature and voltage to either maintain conditions, or change the conditions to vary the progress of the electrophoresis. Gel molds are provided for forming the lanes in a gel plate, as well as a light module, for reading the bands present in the gel lanes with the photometer.
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公开(公告)号：US5667654A
公开(公告)日：1997-09-16
申请号：US606454
申请日：1996-02-23
IPC分类号： G01N27/447 , G01N27/26
CPC分类号： G01N27/44773 , G01N27/44726
摘要： Methods are provided for assaying electrophoretically separated components of sample in a gel. Following an initial separation phase of the sample components into distinct bands within separate zones of the gel, the separated components are held stationary on the gel in a hold mode. During the hold mode, reagent required for an intended assay is applied to the zone of the gel comprising the component to be assayed. The assay is conducted during the hold-mode. A wide range of assays can be conducted on the components in the gel, without the need for a blotting step. Following completion of the assay, the hold mode is removed and, if desired, the sample components are further separated in the gel.
摘要翻译： 提供了用于测定凝胶中样品的电泳分离组分的方法。 在将样品组分初始分离到凝胶的不同区域内的不同条带之前，分离的组分在保持模式下保持在凝胶上。 在保持模式期间，将期望测定所需的试剂施加到包含要测定的组分的凝胶区域。 在保持模式期间进行测定。 可以对凝胶中的组分进行广泛的测定，而不需要印迹步骤。 完成测定后，除去保持模式，如果需要，样品组分在凝胶中进一步分离。
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4.发明授权Gel electrophoresis system including optical stage, sample applicator and sample retriever 失效凝胶电泳系统，包括光学平台，样品涂布器和样品回收器
公开(公告)号：US5275710A
公开(公告)日：1994-01-04
申请号：US837067
申请日：1992-02-14
申请人： Erich A. Gombocz , Alex T. Roth
发明人： Erich A. Gombocz , Alex T. Roth
IPC分类号： G01N27/447 , G01N27/26 , B01D57/02
CPC分类号： G01N27/44704 , G01N27/44721 , G01N27/44782
摘要： An electrophoretic system is provided which allows for carrying out electrophoresis while monitoring and regulating the temperature and the electrical field gradient in the gel. In addition, photometric monitoring, including use of an optical stage, is provided so as to monitor the progress of the electrophoretic separation and vary conditions to change the progress as desired. A computer is employed which receives the signals from the electrophoretic and photometric apparatuses and regulates temperature and voltage to either maintain conditions, or change the conditions to vary the progress of the electrophoresis and to store the separation results. A sample applicator and a sample retriever are also provided, to provide even and consistent application of sample to the gel and to allow recovery of portions of the sample without destroying or removing pieces from the gel. Gel molds are provided for forming the lanes in a gel plate, as well as a light module, for reading the bands present in the gel lanes with the photometer.
摘要翻译： 提供了一种电泳系统，其允许进行电泳，同时监测和调节凝胶中的温度和电场梯度。 此外，提供包括使用光学级的光度监测，以监视电泳分离的进展并改变条件以根据需要改变进展。 接收来自电泳和测光装置的信号并调节温度和电压以维持条件或改变条件以改变电泳进程并存储分离结果的计算机。 还提供样品施加器和样品回收器，以将样品均匀且一致地应用于凝胶并允许回收部分样品而不破坏或从凝胶中除去碎片。 提供凝胶模具用于在凝胶板中形成通道以及光模块，用于通过光度计读取凝胶通道中存在的条带。
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公开(公告)号：US20100223295A1
公开(公告)日：2010-09-02
申请号：US12758415
申请日：2010-04-12
CPC分类号： G06F16/284
摘要： Novel tools and techniques for generating and/or implementing an applied semantic knowledgebase. Some tools allow for data integration into coherent, semantically connected networks and for generation of sets of query-based models describing complex functional relationships as sub-networks. In an aspect, an applied semantic knowledgebase may comprise collections of SPARQL network queries describing a specific set of sub-network relationships and their applicable ranges for each element in the query.
摘要翻译： 用于生成和/或实现应用语义知识库的新工具和技术。 一些工具允许将数据集成到一致的语义连接的网络中，并且用于生成描述作为子网络的复杂功能关系的基于查询的模型的集合。 在一方面，应用的语义知识库可以包括描述特定的一组子网络关系的SPARQL网络查询的集合及其对查询中的每个元素的适用范围。
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6.发明授权System, method, software architecture, and business model for an intelligent object based information technology platform 有权基于智能对象的信息技术平台的系统，方法，软件架构和业务模型公开(公告)号：US07702639B2
公开(公告)日：2010-04-20
申请号：US11217796
申请日：2005-08-31
CPC分类号： G06F17/30286 , Y10S707/99944 , Y10S707/99945
摘要： In one aspect, the invention provides an architecture and query and processing methodology, advantageously implemented in software, for an information technology platform using Intelligent Molecular Objects or objects of a more general character. In another aspect, it provides intelligent molecular object data or other data for heterogeneous data environments with high data density and dynamic application needs. In yet another, it provides an Object State Engine for intelligent molecular object data technology. In still another, it provides an Object Translation Engine for intelligent molecular object data in heterogeneous data environments with dynamic application needs. In yet another aspect, it provides a handling device including an Intelligent Object Handler for intelligent molecular object data in heterogeneous data environments with high data density and dynamic application needs. In even still another aspect, the invention provides a data pool architecture and an Intelligent Object Pool for intelligent molecular object data in heterogeneous data environments with high data density and dynamic application needs. An architecture for an information technology platform using Intelligent Molecular Object software is provided, which addresses all steps of data processing from data acquisition through diverse sources and instrumentation to final output of diverse data analysis results.
摘要翻译： 在一个方面，本发明提供了一种有利于软件实现的用于使用智能分子对象或更一般特征的对象的信息技术平台的架构和查询和处理方法。 另一方面，它为具有高数据密度和动态应用需求的异构数据环境提供智能分子对象数据或其他数据。 另一方面，它为智能分子对象数据技术提供了一个对象状态引擎。 另一方面，它为具有动态应用需求的异构数据环境中的智能分子对象数据提供了一个对象翻译引擎。 在另一方面，它提供了一种处理装置，其包括用于具有高数据密度和动态应用需求的异构数据环境中的智能分析对象数据的智能对象处理器。 在另一方面，本发明为具有高数据密度和动态应用需求的异构数据环境中的智能分析对象数据提供数据池架构和智能对象池。 提供了一个使用智能分子对象软件的信息技术平台的体系结构，它将数据处理的所有步骤从数据采集到各种来源和仪器，到最终输出各种数据分析结果。
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公开(公告)号：US06988109B2
公开(公告)日：2006-01-17
申请号：US10010086
申请日：2001-12-06
IPC分类号： G06F17/30
CPC分类号： G06F17/30286 , Y10S707/99944 , Y10S707/99945
摘要： In one aspect, the invention provides an architecture and query and processing methodology, advantageously implemented in software, for an information technology platform using Intelligent Molecular Objects or objects of a more general character. In another aspect, it provides intelligent molecular object data or other data for heterogeneous data environments with high data density and dynamic application needs. In yet another, it provides an Object State Engine for intelligent molecular object data technology. In still another, it provides an Object Translation Engine for intelligent molecular object data in heterogeneous data environments with dynamic application needs. In yet another aspect, it provides a handling device including an Intelligent Object Handler for intelligent molecular object data in heterogeneous data environments with high data density and dynamic application needs. In even still another aspect, the invention provides a data pool architecture and an Intelligent Object Pool for intelligent molecular object data in heterogeneous data environments with high data density and dynamic application needs. An architecture for an information technology platform using Intelligent Molecular Object software is provided, which addresses all steps of data processing from data acquisition through diverse sources and instrumentation to final output of diverse data analysis results.
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