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公开(公告)号：US10226246B2
公开(公告)日：2019-03-12
申请号：US14881533
申请日：2015-10-13
发明人： Kevin D. Felder , John F. Cummings , Joseph P. Schowalter , Patrick J. Swindon , Johnny H. Alexander, III , Patrick A. Weizman , Cory G. Kimball , Edward G. Chekan , Joseph E. Young , Christopher C. Miller , Barry T. Jamison , John V. Hunt , Kent P. Baker , Cortney E. Henderson , Chester O. Baxter, III , Jerome R. Morgan , Adam R. Dunki-Jacobs , Venkataramanan Mandakolathur Vasudevan , Carl J. Shurtleff , Julia F. Serber
IPC分类号： A61B17/072 , A61B17/064 , A61B17/068 , A61B17/115 , A61B17/00 , A61B17/29 , A61B90/00
摘要： A surgical instrument includes a handle assembly having a trigger operable to fire a staple driver to staple tissue. The instrument includes a pointed rod to which an anvil may be coupled. An anvil detection feature is included to determine when the anvil is coupled to the rod. In some versions, the anvil detection feature comprises a translatable rod that inhibits a lockout feature from disengaging. In other versions, an anvil sensing tube is disposed about the pointed rod and interferes with actuation of the trigger in a first position. A recess in the tube permits trigger to actuate when the anvil sensing tube is in the second position. Alternatively, a resilient tab is coupled to the pointed rod and resists actuation of the staple driver. A trigger lockout assembly may include a spring-loaded button that “pops” out when a push rod is actuated, thereby freeing a pivotable lockout feature.
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公开(公告)号：US09717496B2
公开(公告)日：2017-08-01
申请号：US14944387
申请日：2015-11-18
发明人： Venkataramanan Mandakolathur Vasudevan , Edward G. Chekan , Kevin D. Felder , Jerome R. Morgan , Carl J. Shurtleff, IV , Johnny H. Alexander, III , John F. Cummings , Christopher C. Miller
IPC分类号： A61B17/115 , A61B17/064 , A61B17/068 , A61B17/072
CPC分类号： A61B17/068 , A61B17/115 , A61B17/1155
摘要： A surgical stapling instrument for performing a circular anastomosis comprises a stapling head assembly, an actuator handle assembly, a shaft assembly, a safety latch, and a locking member. The stapling head assembly includes an anvil that moves relative to a staple holder and a staple driver to drive staples from the staple holder into tissue and against the anvil. The actuator handle assembly has a first actuator that controls motion of the anvil and a second actuator that controls motion of the staple driver. The shaft assembly couples the stapling head assembly to the actuator handle assembly. The safety latch prevents operation of the second actuator when the gap between the anvil and staple holder is outside a predetermined range. The locking member is configured to prevent adjustment of the anvil gap after the desired staple height has been set inside the predetermined range.
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公开(公告)号：US20150196293A1
公开(公告)日：2015-07-16
申请号：US14671357
申请日：2015-03-27
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0487 , A61B17/29 , A61B2017/00349 , A61B2017/00818 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/2905 , A61B2017/2927
摘要： Devices and methods for forming and securing a tissue plication are disclosed herein. In one aspect, a tissue manipulation device is described that includes a first jaw member pivotally coupled to a distal end of an elongate shaft and having an articulating portion located distal to the proximal end of the first jaw member. The device also includes a second jaw member pivotally coupled to the first jaw member such that the jaws move in a first plane, and a fastener delivery member attached to the second jaw member. The articulating portion of the first jaw member is configured to move the first and second jaw members between a straight configuration in which a longitudinal axis of the elongate shaft is contained within the first plane and an articulated configuration in which the longitudinal axis of the elongate shaft is transverse to the first plane.
摘要翻译： 本文公开了用于形成和固定组织褶皱的装置和方法。 在一个方面，描述了一种组织操纵装置，其包括枢转地联接到细长轴的远端并且具有位于第一钳口构件的近端远端的铰接部分的第一钳口构件。 该装置还包括枢转地联接到第一钳口构件的第二钳口构件，使得钳口在第一平面中移动，以及附接到第二钳口构件的紧固件输送构件。 第一钳口构件的铰接部分构造成使第一和第二钳口构件在其中细长轴的纵向轴线被容纳在第一平面内的直线构型和铰接构型之间移动，其中细长轴的纵向轴线 横向于第一平面。
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公开(公告)号：US11154559B2
公开(公告)日：2021-10-26
申请号：US13631095
申请日：2012-09-28
IPC分类号： A61K31/56 , A61K35/413
摘要： Methods and compositions are provided for treating metabolic disorders by modulating bile acid levels. Generally, the methods and compositions can modulate bile acid levels, such as serum bile acid levels, to treat a metabolic disorder. In one embodiment, a method of modulating a bile acid level includes measuring a bile acid level and delivering a composition effective to modulate the bile acid level. A method for modulating a bile acid profile includes comparing a bile acid profile to a target profile and delivering a bile acid cocktail to increase bile acid levels. In another embodiment, a pharmaceutical composition for increasing bile acid levels includes a bile acid cocktail effective to increase bile acid levels. The composition is further useful as part of an implantable system.
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公开(公告)号：US10350099B2
公开(公告)日：2019-07-16
申请号：US13644175
申请日：2012-10-03
发明人： Thomas E. Albrecht , Mark S. Zeiner , Jason L Harris , Michael J. Stokes , Mark S. Ortiz , Kevin D. Felder , Michele D'Arcangelo , James W. Voegele
摘要： An endoluminal sleeve device for internally lining a section of the GI tract, comprises a sleeve configured for deployment inside a duodenum, the sleeve having walls of a flexible material defining a sleeve lumen, a proximal end defining a proximal lumen opening, and a distal end defining a distal lumen opening, an anchoring component having a slender transport configuration and a bulky deployed configuration, wherein the anchoring component is locatable at a distance from the proximal sleeve end and connected thereto by an elongated tether.
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公开(公告)号：US20160066906A1
公开(公告)日：2016-03-10
申请号：US14944387
申请日：2015-11-18
发明人： Venkataramanan Mandakolathur Vasudevan , Edward G. Chekan , Kevin D. Felder , Jerome R. Morgan , Carl J. Shurtleff, IV , Johnny H. Alexander, III , John F. Cummings , Christopher C. Miller
IPC分类号： A61B17/068
CPC分类号： A61B17/068 , A61B17/115 , A61B17/1155
摘要： A surgical stapling instrument for performing a circular anastomosis comprises a stapling head assembly, an actuator handle assembly, a shaft assembly, a safety latch, and a locking member. The stapling head assembly includes an anvil that moves relative to a staple holder and a staple driver to drive staples from the staple holder into tissue and against the anvil. The actuator handle assembly has a first actuator that controls motion of the anvil and a second actuator that controls motion of the staple driver. The shaft assembly couples the stapling head assembly to the actuator handle assembly. The safety latch prevents operation of the second actuator when the gap between the anvil and staple holder is outside a predetermined range. The locking member is configured to prevent adjustment of the anvil gap after the desired staple height has been set inside the predetermined range.
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公开(公告)号：US20160030038A1
公开(公告)日：2016-02-04
申请号：US14881533
申请日：2015-10-13
发明人： Kevin D. Felder , John F. Cummings , Joseph P. Schowalter , Patrick J. Swindon , Johnny H. Alexander , Patrick A. Weizman , Cory G. Kimball , Edward G. Chekan , Joseph E. Young , Christopher C. Miller , Barry T. Jamison , John V. Hunt , Kent P. Baker , Cortney E. Henderson , Chester O. Baxter, III , Jerome R. Morgan , Adam R. Dunki-Jacobs , Venkataramanan Mandakolathur Vasudevan , Carl J. Shurtleff , Julia F. Serber
IPC分类号： A61B17/064
CPC分类号： A61B17/064 , A61B17/0686 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B17/1155 , A61B2017/00876 , A61B2017/07214 , A61B2017/0725 , A61B2017/2946 , A61B2090/0811
摘要： A surgical instrument includes a handle assembly having a trigger operable to fire a staple driver to staple tissue. The instrument includes a pointed rod to which an anvil may be coupled. An anvil detection feature is included to determine when the anvil is coupled to the rod. In some versions, the anvil detection feature comprises a translatable rod that inhibits a lockout feature from disengaging. In other versions, an anvil sensing tube is disposed about the pointed rod and interferes with actuation of the trigger in a first position. A recess in the tube permits trigger to actuate when the anvil sensing tube is in the second position. Alternatively, a resilient tab is coupled to the pointed rod and resists actuation of the staple driver. A trigger lockout assembly may include a spring-loaded button that “pops” out when a push rod is actuated, thereby freeing a pivotable lockout feature.
摘要翻译： 一种手术器械包括具有触发器的手柄组件，该触发器可操作以将钉子驱动器射击至钉组织。 该仪器包括可连接砧座的尖杆。 包括砧检测功能以确定砧座何时与杆连接。 在一些形式中，砧座检测特征包括一个能够阻止锁定特征脱离的可平移杆。 在其他形式中，砧感知管围绕尖的杆设置并且在第一位置上干扰触发器的致动。 当砧座感测管处于第二位置时，管中的凹部允许触发器致动。 或者，弹性突舌连接到尖的杆并抵抗钉驱动器的致动。 触发器锁定组件可以包括弹簧加载的按钮，当按压推杆时“弹出”按钮，从而释放可枢转的锁定特征。
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公开(公告)号：US20140330298A1
公开(公告)日：2014-11-06
申请号：US14257245
申请日：2014-04-21
发明人： Susan G. Arshonsky , Jonathan T. Batross , William D. Dannaher , Craig T. Davis , Kristen G. Denzinger , Carl J. Draginoff, Jr. , Craig N. Faller , Kevin D. Felder , Thomas C. Gallmeyer , Jacob S. Gee , Kevin L. Houser , Michael R. Lamping , Amy L. Marcotte , Jeffrey D. Messerly , Rudolph H. Nobis , John B. Schulte , Richard C. Smith , Richard W. Timm
IPC分类号： A61B17/32
CPC分类号： A61B17/320092 , A61B17/295 , A61B2017/00115 , A61B2017/2901 , A61B2017/2902 , A61B2017/2932 , A61B2017/2937 , A61B2017/2939 , A61B2017/294 , A61B2017/2946 , A61B2017/320069 , A61B2017/32007 , A61B2017/320071 , A61B2017/320078 , A61B2017/320089 , A61B2017/320093 , A61B2017/320094 , A61B2017/320095 , A61B2090/035 , A61B2090/036 , A61B2090/0813 , A61B2090/0814
摘要： A surgical apparatus comprises a body, an ultrasonic transducer, a shaft, an acoustic waveguide, an articulation section, and an end effector. The ultrasonic transducer is operable to convert electrical power into ultrasonic vibrations. The shaft couples the end effector and the body together. The acoustic waveguide is coupled with the transducer. The end effector comprises a clamp arm and an ultrasonic blade in acoustic communication with the ultrasonic transducer. The clamp arm is configured to pivot toward and away from the ultrasonic blade. The shaft assembly comprises an inner tube configured to longitudinally translate to thereby pivot the clamp arm toward and away from the ultrasonic blade. A distal portion of the inner tube is operable to flex to thereby accommodate pivoting of the clamp arm.
摘要翻译： 手术装置包括主体，超声波换能器，轴，声波导，关节运动部分和末端执行器。 超声波换能器可操作以将电力转换成超声波振动。 轴将末端执行器和身体连接在一起。 声波导与传感器耦合。 末端执行器包括与超声换能器声学连通的夹臂和超声波刀片。 夹持臂构造成朝向和远离超声波叶片枢转。 轴组件包括构造成纵向平移的内管，从而使夹紧臂朝向和远离超声波叶片枢转。 内管的远端部分可操作以弯曲，从而容纳夹紧臂的枢转。
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公开(公告)号：US10292703B2
公开(公告)日：2019-05-21
申请号：US14880537
申请日：2015-10-12
IPC分类号： A61B17/072 , A61B17/068 , A61B90/00 , A61B17/00 , A61B17/30 , A61B17/29
摘要： Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create multiple tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a method of gastric volume reduction is disclosed that includes advancing a tissue acquisition and fixation device endoscopically into a stomach, manipulating the device to form a first fold of tissue on an interior surface of an anterior wall of the stomach, and manipulating the device to form a second fold of tissue on an interior surface of a posterior wall of the stomach, where the second fold is not attached to the first fold.
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公开(公告)号：US09993260B2
公开(公告)日：2018-06-12
申请号：US14552552
申请日：2014-11-25
发明人： Michael J. Stokes , Jacob S. Gee , Kevin D. Felder , Taylor C. Muhlenkamp , Patrick J. Scoggins , Craig N. Faller , Jeffrey D. Messerly , David J. Cagle , William B. Weisenburgh
CPC分类号： A61B17/320092 , A61B17/320068 , A61B18/1442 , A61B2017/00353 , A61B2017/2825 , A61B2017/320078 , A61B2017/320084 , A61B2018/00011 , A61B2018/00107 , A61B2018/0063 , A61B2090/0436 , A61B2090/0472 , A61N7/00
摘要： An apparatus comprises a body, a shaft assembly, an end effector, and a shield member. The shaft assembly extends distally from the body. The end effector is located at a distal end of the shaft assembly. The end effector comprises an ultrasonic blade and a clamp arm. The ultrasonic blade is configured to vibrate at an ultrasonic frequency. The clamp arm is movable toward the ultrasonic blade to compress tissue against the ultrasonic blade. The shield member is selectively movable from a first position to a second position in response to movement of the clamp arm toward the ultrasonic blade. The shield member is configured cover at least a first portion of the ultrasonic blade in the first position. The shield member is configured to uncover the first portion of the ultrasonic blade in the second position.
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