-
公开(公告)号：US20120128682A1
公开(公告)日：2012-05-24
申请号：US13388645
申请日：2010-08-18
IPC分类号： A61K39/395 , C07H21/04 , C12N15/63 , A61K38/00 , A61K31/7088 , A61P3/06 , A61P33/00 , C12Q1/04 , G01N33/53 , C12Q1/68 , C07K16/12 , C12N5/10 , C07K16/18 , A01K67/027 , A61K35/14 , A61K35/16 , C07K14/775
CPC分类号： G01N33/92 , C07K14/775 , C12Q1/6876 , C12Q2600/124 , C12Q2600/158 , G01N2800/347
摘要： An isolated human Apolipoprotein L-I corresponding to a wild type human Apolipoprotein sequence is modified by a deletion at its C-terminal end.
摘要翻译： 对应于野生型人载脂蛋白序列的分离的人载脂蛋白L-1在其C末端被缺失修饰。
-
2.发明授权Apolipoprotein L-I and/or derivated polypeptide for the treatment of and/or the prevention of diseases induced by trypanosoma 有权用于治疗和/或预防由锥虫病引起的疾病的载脂蛋白L-1和/或衍生多肽公开(公告)号：US07585511B2
公开(公告)日：2009-09-08
申请号：US10523466
申请日：2003-08-04
IPC分类号： A61K39/002
CPC分类号： C12Q1/6893 , A01K2227/101 , A61K38/17 , A61K38/1709 , G01N33/92 , Y02A50/415
摘要： The present invention is related to a composition comprising apolipoprotein L-l, the use of apolipoprotein L-l or a derivated polypeptide for the diagnostic, the treatment and/or the prevention of diseases induced in mammals by Trypanosoma. Another aspect is related to a transgenic non-human mammal comprising a polynucleotide expressing the apolipoprotein L-l or a derivated polypeptide and which is tolerant or resistant to the Trypanosoma infection.
摘要翻译： 本发明涉及包含载脂蛋白L-1，载脂蛋白L-1或衍生多肽用于诊断，治疗和/或预防由锥虫病在哺乳动物中诱导的疾病的组合物的组合物。 另一方面涉及包含表达载脂蛋白L-1或衍生多肽并且对锥虫病感染具有耐受性或抗性的多核苷酸的转基因非人哺乳动物。
-
3.发明申请PHARMACEUTICAL COMPOSITION COMPRISING APOLIPOPROTEINS FOR THE TREATMENT OF HUMAN DISEASES 审中-公开包含APOLIPOPROTEIN治疗人类疾病的药物组合物公开(公告)号：US20090162333A1
公开(公告)日：2009-06-25
申请号：US12300569
申请日：2007-05-25
申请人： Etienne Pays , Benoit Vanhollebeke
发明人： Etienne Pays , Benoit Vanhollebeke
IPC分类号： A61K48/00 , A61K38/17 , A61K31/7105 , A61P35/00 , A61P25/18 , A61P29/00 , A61K31/711 , A61K35/12
CPC分类号： A61K38/17
摘要： A pharmaceutical composition has an adequate pharmaceutical carrier or diluent and an element selected from a pharmaceutical composition having an adequate pharmaceutical carrier or diluent and an element selected from: —apolipoprotein apoL-III; —a pharmaceutically active fragment of this apolipoprotein apoL-III; —a nucleotide sequence encoding this apolipoprotein apoL-III or the fragment; —a vector having the nucleotide sequence; —a cell transformed by the nucleotide sequence or the vector; —an inhibitor or activator directed against the apolipoprotein apoL-III, its fragment or its nucleotide sequence, —an anti-inhibitor or anti-activator directed against the inhibitor or activator or its encoding nucleotide sequence.
摘要翻译： 药物组合物具有足够的药物载体或稀释剂和选自具有足够的药物载体或稀释剂的药物组合物和选自以下的元素的元素：脂蛋白载体-III; - 该载脂蛋白apoL-III的药物活性片段; - 编码该载脂蛋白apoL-III或片段的核苷酸序列; 具有该核苷酸序列的载体; - 由核苷酸序列或载体转化的细胞; - 针对载脂蛋白apoL-III，其片段或其核苷酸序列的抑制剂或活化剂 - 针对抑制剂或活化剂的抗抑制剂或抗激活剂或其编码核苷酸序列。
-
4.发明授权公开(公告)号：US09119817B2
公开(公告)日：2015-09-01
申请号：US14000079
申请日：2012-02-17
申请人： Etienne Pays
发明人： Etienne Pays
CPC分类号： A61K38/1709 , A61K38/17 , Y02A50/415
摘要： A wild-type human Apolipoprotein L-I is used in a method for the prevention and/or the treatment of renal disease.
摘要翻译： 野生型人载脂蛋白L-1用于预防和/或治疗肾脏疾病的方法。
-
5.发明申请WILD-TYPE APOLIPOPROTEIN L-I FOR USE IN THE PREVENTION OF KIDNEY DISEASES 有权野生型APOLIPOPROTEIN L-I用于预防儿童疾病公开(公告)号：US20140057849A1
公开(公告)日：2014-02-27
申请号：US14000079
申请日：2012-02-17
申请人： Etienne Pays
发明人： Etienne Pays
IPC分类号： A61K38/17
CPC分类号： A61K38/1709 , A61K38/17 , Y02A50/415
摘要： A wild-type human Apolipoprotein L-I is used in a method for the prevention and/or the treatment of renal disease.
摘要翻译： 野生型人载脂蛋白L-1用于预防和/或治疗肾脏疾病的方法。
-
6.发明申请Apolipoprotein l-i and/or derivated polypeptide for the treatment of and/or the prevention of diseases induced by trypanosoma 有权用于治疗和/或预防由锥虫病引起的疾病的载脂蛋白I-1和/或衍生多肽公开(公告)号：US20060263348A1
公开(公告)日：2006-11-23
申请号：US10523466
申请日：2003-08-04
IPC分类号： A61K39/395 , A61K38/17 , C07K14/775
CPC分类号： C12Q1/6893 , A01K2227/101 , A61K38/17 , A61K38/1709 , G01N33/92 , Y02A50/415
摘要： The present invention is related to a composition comprising apolipoprotein L-1, the use of apolipoprotein L-1 or a derivated polypeptide for the diagnostic, the treatment and/or the prevention of diseases induced in mammals by Trypanosoma. Another aspect is related to a transgenic non-human mammal comprising a polynucleotide expressing the apolipoprotein L-1 or a derivated polypeptide and which is tolerant or resistant to the Trypanosoma infection.
摘要翻译： 本发明涉及包含载脂蛋白L-1，载脂蛋白L-1或衍生多肽用于诊断，治疗和/或预防由锥虫病在哺乳动物中诱导的疾病的组合物的组合物。 另一方面涉及包含表达载脂蛋白L-1或衍生多肽并且对锥虫病感染具有耐受性或抗性的多核苷酸的转基因非人哺乳动物。
-
-
-
-
-
搜索结果
6 条记录 (耗时 0.014 秒)
